▍ Selected Publications

1272. Rational design of rigid mRNA folding architecture to enhance intracellular processing and protein production.

Yang, B., Li, B., Zhu, Y. et al.

Nat. Nanotechnol. March 2026. doi: 10.1038/s41565-025-02114-9

https://doi.org/10.1038/s41565-025-02114-9

1271. X-ray activated platinum complex induces DNA damage and enhances cancer immunotherapythrough abscopal effect.

Chen G, LiX, Huang Y, Zheng C, Fang H, Zhang Q, Liu K, Wu K, Zhu Q, Guo C, Zhu H, Dai R,He Y, Zhu Q, Zhou W, Yang Y, Li Z, Qu K, Li B, Xiao S, Tian S, Xing B, Chen X,Wang AZ, Xiong Y, Min Y..

Nat BiomedEng. 2026 Feb 9. doi: 10.1038/s41551-026-01612-y. Online ahead of print..

https://pubmed.ncbi.nlm.nih.gov/41663744/

1270. Spatiotemporaldynamics of land use transition impacts on carbon emissions in the pearl riverdelta.

Wang W,Zhang Y, Hu Y, Chen X, Mao X, Tang L, Cai J..

Sci Rep. 2026 Feb 6.doi: 10.1038/s41598-026-38176-5. Online ahead of print..

https://pubmed.ncbi.nlm.nih.gov/41651958/

1269. Gram-ScaleSynthesis of Hafnium-Rich Carbon Dots for Preclinical Computed TomographyImaging Across Various Systems.

Li S, Wu H,Deng J, Sun Q, Zhang Y, Zhang C, Pan J, Liu D, Zhang X, Zou Q, Chen X, Sun SK..

Adv Sci(Weinh). 2026 Jan 31:e17986. doi: 10.1002/advs.202517986. Onlineahead of print..

https://pubmed.ncbi.nlm.nih.gov/41619262/

1268. BODIPY-DopedNanocarrier Engineering (BONE) Improves Bone Marrow mRNA Delivery by NIR-IIBioimaging Guided Screening.

Li B, WangJ, Peng Y, Liu C, Ming Y, Yang B, He D, Lai W, Guo L, Zhao M, Chen X..

J Am ChemSoc. 2026Jan 30. doi: 10.1021/jacs.5c14271. Online ahead of print..

https://pubmed.ncbi.nlm.nih.gov/41615274/

1267. EngineeredVPg saRNA achieves cap-independent, low-immunogenic and precise encoding oftherapeutic proteins in vivo.

Feng Z, ChuL, Li Q, Zhou J, Wu P, Zhang X, Pan Y, Zou J, Chen Q, Xu Z, Yan L, Huang Y, LiX, Wang Z, Chen X..

Nat Commun. 2026 Jan 27.doi: 10.1038/s41467-026-68364-w. Online ahead of print..

https://pubmed.ncbi.nlm.nih.gov/41593087/

1266. Sarcopenicobesity increases the risk of falls in early-onset type 2 diabetes.

Chen X,Zhang Y, Zheng B, Shen X, Huang L, Zhao F, Yan S..

J EndocrinolInvest. 2026 Jan 27. doi: 10.1007/s40618-026-02814-6. Online aheadof print..

https://pubmed.ncbi.nlm.nih.gov/41591735/

1265. Tmem110regulates the conformation of TRPML1 to maintain endolysosomal homeostasis andprevent mitochondrial DNA leakage and pathological self-DNA processing.

Feng Z, PanY, Zhou J, Chu L, Li Q, Zhang X, Wu P, Xu Z, Huang Y, Zou J, Li X, Chen X, WangZ..

Nat Commun. 2026 Jan 15.doi: 10.1038/s41467-026-68382-8. Online ahead of print..

https://pubmed.ncbi.nlm.nih.gov/41540067/

1264. TargetingPeptostreptococcus anaerobius with an Iron-Based Nanozyme Reverses FerroptosisResistance and Enhances Antitumor Immunity in Colorectal Cancer.

Cao Y, WangJ, Wang H, Sun X, Fang F, Li S, Liu J, Shi C, Qi P, Zou J, Chen X, Cai K..

Adv Sci(Weinh). 2026 Jan 12:e16272. doi: 10.1002/advs.202516272. Onlineahead of print..

https://pubmed.ncbi.nlm.nih.gov/41524179/

1263. Side-ChainEngineering Guides the Design of β-Sheet Inhibitor to Anchor Protein-ProteinInteraction Interfaces.

Zhang L,Wang M, Wang B, Zhao J, Sun B, Yu Y, Han K, Wang X, Zhang J, Wei M, Deng J, LiJ, Li M, Ke Y, Jiang H, Yan H, Chen X, Peng X, Bai Y, Wang W..

Angew ChemInt Ed Engl. 2026 Jan 7:e21473. doi: 10.1002/anie.202521473. Onlineahead of print..

https://pubmed.ncbi.nlm.nih.gov/41498183/

1262. Abiohybrid chiral hydrogel enhances preclinical postoperative glioblastomatherapy by multi-pronged inhibition of tumour stemness.

Cui T, ChenS, Liu S, Niu X, Wang J, Ao R, Cai H, Huang H, Yu M, Peng S, Chen X, Lin L..

NatNanotechnol. 2026 Jan;21(1):140-155. doi:10.1038/s41565-025-02064-2. Epub 2025 Dec 26..

https://pubmed.ncbi.nlm.nih.gov/41454130/

1261. Precision-ArchitectedDrug-Stabilized Cu(5) Clusters Mediate Multimodal Therapeutic Intervention inColitis.

Sang Y,Zhang Y, Chen SY, Zang QX, Wang ZY, Chen X, Zang SQ..

ACS Nano. 2026 Jan13;20(1):300-316. doi: 10.1021/acsnano.5c12046. Epub 2025 Dec 22..

https://pubmed.ncbi.nlm.nih.gov/41429761/

1260. LeveragingCisplatin-Derived Prodrugs as Helper Lipids in LNPs to Boost the Efficacy ofCancer Chemoimmunotherapy.

Zhang X,Ning S, Fang F, Zhou C, Yang Z, Cao L, Wang K, Feng Z, Li B, Luo D, Xu X, LiuZ, Chen X, Yu Z..

ACS Nano. 2026 Jan13;20(1):1448-1461. doi: 10.1021/acsnano.5c18243. Epub 2025 Dec 22..

https://pubmed.ncbi.nlm.nih.gov/41424446/

1259. Editorial:Novel ultrasound-based strategies for precision therapeutics and visualization.

Cui X, ChenX..

Adv DrugDeliv Rev. 2026 Mar;230:115763. doi: 10.1016/j.addr.2025.115763. Epub2025 Dec 16..

https://pubmed.ncbi.nlm.nih.gov/41412345/

1258. AnUltralong-Circulating Tantalum-Based Computed Tomography Contrast Agent forVascular Imaging in Large Animals.

Shu G, LangM, Deng J, Zhang Y, Cheng R, Pan J, Wang X, Liu D, Zhang C, Chen X, Sun SK..

ACS Nano. 2026 Jan13;20(1):507-521. doi: 10.1021/acsnano.5c13773. Epub 2025 Dec 17..

https://pubmed.ncbi.nlm.nih.gov/41408730/

1257. Tumortargeted radionuclide-nanomedicine for clinical translation: From carrierinnovation to precision therapy.

Wei Z, ZhenW, Chen X, Zhang J..

J ControlRelease. 2026 Feb 10;390:114543. doi:10.1016/j.jconrel.2025.114543. Epub 2025 Dec 12..

https://pubmed.ncbi.nlm.nih.gov/41391729/

1256. Impactof Non-Alcoholic Fatty Liver Disease on the HBsAg Loss of Patients With ChronicHepatitis B Treated in Pegylated Interferon Alpha.

Li C, Lin L,Zhou P, Cai H, Liu S, Chen X, Lu A, Li B, Wang Y, Luo C, Li J, Guan Y, Xie Z..

J ViralHepat.2026 Jan;33(1):e70115. doi: 10.1111/jvh.70115..

https://pubmed.ncbi.nlm.nih.gov/41384319/

1255. AI-GuidedSERS Defines a Pan-Cancer Diagnostic Biomarker.

Zhang C,Zhao WH, Zuo D, Zhou T, Hou W, Wang L, Shi S, Yang Y, Liu Y, Sun SK, Ren L, YeZ, Liu D, Li D, Chen X, Hao J..

Adv Sci(Weinh). 2026 Feb;13(7):e16268. doi: 10.1002/advs.202516268. Epub2025 Nov 16..

https://pubmed.ncbi.nlm.nih.gov/41243246/

1254. CD169(+)Macrophage-Targeted Immunomodulator to Restore Phagocytic Function and EnhanceAntigen Presentation for LymphaticMetastasis Eradication.

Chen X, LuL, Liu Y, Liang Z, Li J, Shao Z, Tang Y, Zou J, Li S, Chen X..

Adv Sci(Weinh). 2026 Jan;13(6):e14386. doi: 10.1002/advs.202514386. Epub2025 Nov 16..

https://pubmed.ncbi.nlm.nih.gov/41243224/

1253. DualTargeting of m(7)G tRNA Modification and Histone Acetylation using Carrier-FreeNano-Epidrugs to Evoke Osteosarcoma Chemosensitization.

Qi L, ZhangW, Shi C, Feng C, Liu Z, Li Z, Fang F, Chen X..

Adv Mater. 2026Jan;38(4):e05951. doi: 10.1002/adma.202505951. Epub 2025 Oct 10..

https://pubmed.ncbi.nlm.nih.gov/41074238/

1252. NanomedicineReimagined: Translational Strategies for Precision Tumor Theranostics.

Wu Q, Yao X,Duan X, Chen X, Zhang J..

Adv Mater. 2026Feb;38(8):e10293. doi: 10.1002/adma.202510293. Epub 2025 Sep 6..

https://pubmed.ncbi.nlm.nih.gov/40913574/

1251. Proteolysis-targetingchimera (PROTAC) nanomedicines toward cancer treatment: From synthesis totherapeutic delivery.

Liu Y, ZhangX, Chen X, Zhang F..

Biomaterials.2026 Feb;325:123621. doi: 10.1016/j.biomaterials.2025.123621. Epub 2025 Aug 8..

https://pubmed.ncbi.nlm.nih.gov/40819599/

1250. Organoid-drivennanomedicine platform development.

Wang J, WangF, Jiang Y, Bai L, Chen X, Su J..

Biomaterials.2026Feb;325:123611. doi: 10.1016/j.biomaterials.2025.123611. Epub 2025 Aug 7..

https://pubmed.ncbi.nlm.nih.gov/40795706/

 

1249. Patient preferences in thebenefit-risk assessment of atopic dermatitis treatments in China: A nationwidesurvey.

YangJ, Liu Y, Li H, Ge Y, Yin C, Zhai Y, Zhao C, Qian S, Chen X, Xie S.

JAADInt.2025 Nov 27;24:306-314. doi: 10.1016/j.jdin.2025.11.011. eCollection 2026 Feb.

https://pubmed.ncbi.nlm.nih.gov/41561204/

1248. Viralglycoprotein-mimicking peptide-functionalized micelles promote drug delivery todiseased chondrocytes for osteoarthritis alleviation.

ChenX, Zhou D, Wang J, Liu H, Zhang H, Geng Z, Wang G, Shen H, Zhang Y, Li Z, WangD, Ren X, Wang X, Xu K, He C, Bai L, Wei Y, Chen X, Su J.

NatNanotechnol. 2025Dec 29. doi: 10.1038/s41565-025-02082-0. Online ahead of print.

https://pubmed.ncbi.nlm.nih.gov/41461939/

1247. Chronic Ozone Exposure andIts Role in the Development of Age-RelatedCataracts: A Comprehensive Analysis.

ZhouLX, Li JH, Zeng CY, Li XJ, Zhong SY, Wu Y, Wang XY, Chen XY, Huang YX, Xiao XJ,Zheng Y, Wang HJ, Yang P, Liu T.

EnvironHealth (Wash).2025 Aug 4;3(12):1534-1543. doi: 10.1021/envhealth.5c00086. eCollection 2025Dec 19.

https://pubmed.ncbi.nlm.nih.gov/41446765/

1246. Duet between stressgranules and glutathionylation regulates cytosolic redox state to maintainproteostasis in Arabidopsis.

ZhaoS, Xie Z, Chen X, Shi Y, Li H, Li Y, Chen C, Zhou M, Wang W.

MolPlant.2025 Dec 19:S1674-2052(25)00448-4. doi: 10.1016/j.molp.2025.12.018. Onlineahead of print.

https://pubmed.ncbi.nlm.nih.gov/41422380/

1245. Innovations inRadiotherapeutic Materials for Personalized Oncology.

MuJ, Song J, Chen X.

ACSAppl Mater Interfaces.2025 Dec 17;17(50):67399-67400. doi: 10.1021/acsami.5c22930.

https://pubmed.ncbi.nlm.nih.gov/41408731/

1244. AT-17 redefines localanesthetics by targeting mitochondrial apoptosis.

ChenX.

ActaPharm Sin B. 2025Nov;15(11):6087-6088. doi: 10.1016/j.apsb.2025.10.013. Epub 2025 Nov 10.

https://pubmed.ncbi.nlm.nih.gov/41311389/

1243. Engineering aspatiotemporal macrophage circuit via STING phase separation to override immunesuppression in pancreatic cancer.

YangX, Wang Y, Zhou J, Li S, Ye J, Sun Y, He M, Fan K, Chen Z, Tian F, Zhao B,Zhang J, Xie J, Xiao Z, Chen X, Ju S.

ProcNatl Acad Sci U S A.2025 Nov 25;122(47):e2504718122. doi: 10.1073/pnas.2504718122. Epub 2025 Nov 20.

https://pubmed.ncbi.nlm.nih.gov/41264244/

1242. Lipid NanoparticleChaperone with Redox-Adaptive Intracellular Microenvironment ModulationPotentiates the Potency of mRNA Vaccines.

YuX, Qi S, Zhang W, Li H, Cao F, Wang Y, Peng K, Lin X, Chen X, Yu G.

JAm Chem Soc.2025 Dec 3;147(48):44072-44086. doi: 10.1021/jacs.5c10972. Epub 2025 Nov 20.

https://pubmed.ncbi.nlm.nih.gov/41263704/

1241. Glycolysis-inhibiting tumorcell-derived microparticles to enhance immunogenic cell death for synergisticcancer immunotherapy.

ZhangM, Xu J, Yang Z, Ding L, Han H, Ma M, Ee PLR, Yu G, Tang W, Chen X.

Biomaterials. 2026 May;328:123832. doi:10.1016/j.biomaterials.2025.123832. Epub 2025 Nov 2.

https://pubmed.ncbi.nlm.nih.gov/41205277/

1240. Mineralized SupramolecularMicrospheres with Immunoregulating Functions for TransarterialChemoembolization Immunotherapy of Hepatocellular Carcinoma.

ZhangM, Wang Y, Tang X, Zhang W, Mao Z, Yu Y, Yang X, Yu G, Chen X.

SmallMethods. 2025Dec;9(12):e00857. doi: 10.1002/smtd.202500857. Epub 2025 Oct 24.

https://pubmed.ncbi.nlm.nih.gov/41137409/

1239. NIR-II Dual-Modal Photoacoustic andOCT/OCTA Contrast Mechanisms Imaging Microenvironment Responses forPrecision-Guiding Tumor Photothermal Theranostics.

YangL, Li J, Ling S, Du F, Liao W, Li R, Li Y, Zhou Z, Jin Z, Chen X, Zhao Q.

SmallMethods.2025 Dec;9(12):e00955. doi: 10.1002/smtd.202500955. Epub 2025 Oct 13.

https://pubmed.ncbi.nlm.nih.gov/41083813/

1238. UnveilingNovel Viral Diversity, Biogeography, and Host Networks in Wildlife ThroughHigh-Throughput Sequencing Data Mining.

WangH, Meng Y, Chen X, Cui X, Zuo Q, Han N, Liang X, Shen X, Li C, Li D, Wang F, HeL, Chen R, Lu X, You W, Wu A, Chen RA, Chen W, Ding C, Shen Y.

AdvSci (Weinh).2025 Dec;12(46):e11920. doi: 10.1002/advs.202511920. Epub 2025 Sep 23.

https://pubmed.ncbi.nlm.nih.gov/40985348/

1237. PPP1R3B SuppressesAtherosclerosis by Promoting the M2 Polarization of Macrophages ThroughGlycogen Metabolic Reprogramming.

ShenL, Yu J, Chen W, Bi Y, Yang Z, Lu C, Jiang C, Yang Y, Chen M, Zou J, Lv L, ChenX, Ji J.

AdvSci (Weinh). 2025Nov;12(41):e06345. doi: 10.1002/advs.202506345. Epub 2025 Sep 23.

https://pubmed.ncbi.nlm.nih.gov/40984828/

1236. Dual role of Glossy15 inregulating flowering by modulating gibberellins and floral organ geneexpression in maize.

YangJ, Xu G, Zhang M, Xue W, Wu J, Li Y, Song G, Wang B, Liu Y, Chen X, Kong D,Wang H.

NewPhytol. 2025Nov;248(4):2143-2159. doi: 10.1111/nph.70492. Epub 2025 Sep 21.

https://pubmed.ncbi.nlm.nih.gov/40976980/

1235. Advances inradiopharmaceuticals for cancer radiotheranostics: CCK2R targeting as aparadigm for translational innovation.

LiJ, Wen X, Reszegi RR, Kamalrhaj H, Parak WJ, Chen X, Zhang J.

CancerCommun (Lond).2025 Nov;45(11):1431-1455. doi: 10.1002/cac2.70063. Epub 2025 Sep 20.

https://pubmed.ncbi.nlm.nih.gov/40974551/

1234. Targeted ROS Scavenging forDisease Therapies Using Nanomaterials.

ZhangY, Zhang Y, Liang R, Zou J, Pei R, Chen X.

AdvMater. 2025Dec;37(50):e04435. doi: 10.1002/adma.202504435. Epub 2025 Aug 22.

https://pubmed.ncbi.nlm.nih.gov/40844075/

1233. Albumin-recruiting lipidnanoparticle potentiates the safety and efficacy of mRNA vaccines by avoidingliver accumulation.

FengY, Tai W, Huang P, Qi S, Yu X, Li M, Li M, Zhang M, Cao F, Gao X, Yang K, BaiB, Lei J, Cheng M, Li Y, Cheng G, Chen X, Yu G.

NatMater.2025 Nov;24(11):1826-1839. doi: 10.1038/s41563-025-02284-w. Epub 2025 Aug 1.

https://pubmed.ncbi.nlm.nih.gov/40750835/

1232. Spatiotemporal Nano-Regulator UnleashesAnti-Tumor Immunity by Overcoming Dendritic Cell Tolerance and T CellExhaustion in Tumor-Draining Lymph Nodes

Wang R, Li H, He S, Feng Y, Liu C, Hao K, Zhou D,Chen X, Tian H.

Adv Mater. 2025 Feb;37(5):e2412141. doi: 10.1002/adma.202412141.Epub 2024 Dec 11.

https://pubmed.ncbi.nlm.nih.gov/39663685/

1231. Mineralized Supramolecular Microspheres withImmunoregulating Functions for Transarterial Chemoembolization Immunotherapy ofHepatocellular Carcinoma

Zhang M, Wang Y, Tang X, Zhang W, Mao Z, Yu Y, YangX, Yu G, Chen X.

Small Methods. 2025 Oct 24:e00857. doi: 10.1002/smtd.202500857. Onlineahead of print.

https://pubmed.ncbi.nlm.nih.gov/41137409/

1230. Condensate nanovaccine adjuvants augmentCD8(+) T-Cell-dependent antitumor immunity through mtDNA leakage-triggeredcGAS-STING axis activation

Tang Y, Luo Z, Ma Z, Han L, Zhou Y, Liang T, Yang K,Zhao L, Chen X, Zhang P.

Signal Transduct Target Ther. 2025 Oct 21;10(1):349. doi:10.1038/s41392-025-02447-w.

https://pubmed.ncbi.nlm.nih.gov/41115902/

1229. Advanced Clinical Diagnosis of Malaria Usinga Simple Red-Emissive Smart Fluorescent Probe

Ye Y, Zhang S, Chen G, Liu Z, Chen X, Luo R, Zhang Z,Zhao X, Lian J,Yang Z, Samanta S, Yang Z, Xu K.

Anal Chem.2025 Oct 28;97(42):23555-23568. doi:10.1021/acs.analchem.5c04953. Epub 2025 Oct 16.

https://pubmed.ncbi.nlm.nih.gov/41103010/

1228. OsPIP2;1 Positively Regulates Rice Toleranceto Water Stress Under Coupling of Partial Root-Zone Drying and Nitrogen Forms

Kuang C, Han Z, Zhang X, Chen X, Gao Z, Zhu Y.

Int J Mol Sci.2025 Oct 8;26(19):9782. doi: 10.3390/ijms26199782.

https://pubmed.ncbi.nlm.nih.gov/41097046/

1227. Optimal Design of High-Critical-Current SMESMagnets: From Single to Multi-Solenoid Configurations

You H, Li H, Fu L, Shen B, Tang M, Chen X.

Materials (Basel).2025 Oct 1;18(19):4567. doi: 10.3390/ma18194567.

https://pubmed.ncbi.nlm.nih.gov/41095393/

1226. NIR-II Dual-Modal Photoacoustic and OCT/OCTAContrast Mechanisms Imaging Microenvironment Responses for Precision-GuidingTumor Photothermal Theranostics

Yang L, Li J, Ling S, Du F, Liao W, Li R, Li Y, ZhouZ, Jin Z, Chen X, Zhao Q.

Small Methods. 2025 Oct 13:e00955. doi: 10.1002/smtd.202500955. Onlineahead of print. 

https://pubmed.ncbi.nlm.nih.gov/41083813/

 

1225.Dual Targeting of m(7)G tRNA Modification andHistone Acetylation using Carrier-Free Nano-Epidrugs to Evoke OsteosarcomaChemosen sitization

Qi L, Zhang W, Shi C, Feng C, Liu Z, Li Z, Fang F,Chen X.

Adv Mater.2025 Oct 10:e05951. doi: 10.1002/adma.202505951. Onlineahead of print.

https://pubmed.ncbi.nlm.nih.gov/41074238/

1224. Programmable Bimetallic MOF NanozymeComposite with Microenvironment-Adaptive Cascade Catalysis for Wearable GlucoseBiosensing and Accelerated Diabetic Wound Healing

Yu K, Li X, Zhan S, Chai H, Cao X, Cao F, Guan J, XuQ, Gao X, Qu L, Zhang X, Zhang G, Chen X.

Anal Chem.2025 Oct 7;97(39):21668-21678. doi:10.1021/acs.analchem.5c04419. Epub 2025 Sep 26.

https://pubmed.ncbi.nlm.nih.gov/41003546/

1223. Unveiling Novel Viral Diversity,Biogeography, and Host Networks in Wildlife Through High-Throughput SequencingData Mining

Wang H, MengY, Chen X, Cui X, Zuo Q, Han N, Liang X,Shen X, Li C, Li D, Wang F, He L, Chen R, Lu X,You W, Wu A,

Chen RA, Chen W, Ding C, ShenY.

Adv Sci (Weinh).2025 Sep 23:e11920. doi: 10.1002/advs.202511920. Onlineahead of print.

https://pubmed.ncbi.nlm.nih.gov/40985348/

1222. PPP1R3B Suppresses Atherosclerosis byPromoting the M2 Polarization of Macrophages Through Glycogen MetabolicReprogramming

Shen L,Yu J, Chen W, BiY,Yang Z, Lu C, Jiang C,YangY,Chen M, Zou J, Lv L, Chen X, Ji J.

Adv Sci (Weinh). 2025 Sep 23:e06345. doi: 10.1002/advs.202506345. Onlineahead of print.

https://pubmed.ncbi.nlm.nih.gov/40984828/

1221. Dual role of Glossy15 in regulatingflowering by modulating gibberellins and floral organ gene expression in maize

Yang J, Xu G, Zhang M, Xue W, Wu J, LiY, Song G, WangB, LiuY, Chen X, Kong D, Wang H.

New Phytol.2025 Nov;248(4):2143-2159. doi: 10.1111/nph.70492. Epub2025 Sep 21.

https://pubmed.ncbi.nlm.nih.gov/40976980/

1220. Advances in radiopharmaceuticals for cancerradiotheranostics: CCK2R targeting as a paradigm for translational innovation

Li J, Wen X, Reszegi RR, Kamalrhaj H, Parak WJ, ChenX, Zhang J.

Cancer Commun (Lond).2025 Sep 20. doi: 10.1002/cac2.70063. Online ahead ofprint.

https://pubmed.ncbi.nlm.nih.gov/40974551/

1219.ResearchAdvances in AP2/ERF Transcription Factors in Rice Growth and Development

HeY, Li R, Li D, Fan X, Chen X, Zhuang C, Li J.

Plants (Basel).2025 Aug 27;14(17):2673. doi: 10.3390/plants14172673.

https://pubmed.ncbi.nlm.nih.gov/40941839/

1218. From Quantum Dots to Cancer Nanotheranostics

Chen X.

Nano Lett. 2025 Sep 24;25(38):13967-13969. doi:10.1021/acs.nanolett.5c03619. Epub 2025 Sep 9.

https://pubmed.ncbi.nlm.nih.gov/40924918/

1217. Bionic nanomedicines for microwave-triggeredcuproptosis to enhance cancer immunotherapy

Suo M, Wang Z, Zhang S,Tang W, Liang D, Chen X, NingS.

Nanoscale Horiz. 2025 Oct 20;10(11):3003-3012. doi: 10.1039/d5nh00425j.

https://pubmed.ncbi.nlm.nih.gov/40923155/

1216. Nanomedicine Reimagined:TranslationalStrategies for Precision Tumor Theranostics

Wu Q,Yao X, Duan X, Chen X, Zhang J.

Adv Mater. 2025 Sep 6:e10293. doi: 10.1002/adma.202510293. Onlineahead of print.

https://pubmed.ncbi.nlm.nih.gov/40913574/

1215. Targeted ROS Scavenging for DiseaseTherapies Using Nanomaterials

Zhang Y, Zhang Y, Liang R, Zou J, Pei R, Chen X.

Adv Mater. 2025 Aug 22:e04435. doi: 10.1002/adma.202504435. Onlineahead of print.

https://pubmed.ncbi.nlm.nih.gov/40844075/

1214. Proteolysis-targeting chimera (PROTAC)nanomedicines toward cancer treatment: From synthesis to therapeutic delivery

LiuY, Zhang X, Chen X, Zhang F.

Biomaterials.2026 Feb;325:123621. doi:10.1016/j.biomaterials.2025.123621. Epub 2025 Aug 8.

https://pubmed.ncbi.nlm.nih.gov/40819599/

1213. Author Correction: Albumin-recruiting lipidnanoparticle potentiates the safety and efficacy of mRNA vaccines by avoidingliver accumulation

Feng Y, Tai W, Huang P, Qi S,Yu X, Li M, Li M, ZhangM, Cao F, Gao X, Yang K, Bai B, Lei J, Cheng M, LiY, Cheng G, Chen X, Yu G.

Nat Mater. 2025 Nov;24(11):1862. doi: 10.1038/s41563-025-02343-2.

https://pubmed.ncbi.nlm.nih.gov/40797038/

1212. Organoid-driven nanomedicine platformdevelopment

Wang J, Wang F, Jiang Y, Bai L, Chen X, Su J.

Biomaterials. 2026 Feb;325:123611. doi:10.1016/j.biomaterials.2025.123611. Epub 2025 Aug 7.

https://pubmed.ncbi.nlm.nih.gov/40795706/

1211.Albumin-recruitinglipid nanoparticle potentiates the safety and efficacy of mRNA vaccines byavoiding liver accumulation

Feng Y, Tai W, Huang P, Qi S, Yu X, Li M, Li M, ZhangM, Cao F, Gao X, Yang K, Bai B, Lei J, Cheng M, LiY, Cheng G, Chen X, Yu G.

Nat Mater. 2025 Nov;24(11):1826-1839. doi:10.1038/s41563-025-02284-w. Epub 2025 Aug 1.

https://pubmed.ncbi.nlm.nih.gov/40750835/

1210.Trendsin the development of cellular and gene therapy in China

Liu Y, Ge C, Chen X, Lu S, Wang T.

Nat Rev Drug Discov. 2025 Sep;24(9):656-657. doi: 10.1038/d41573-025-00126-7.

https://pubmed.ncbi.nlm.nih.gov/40745209/

1209. Genetically engineered chondrocyte-mimeticnanoplatform attenuates osteoarthritis by blocking IL-1β and restoringsirtuin-3

Deng C,Yu L, Zhao X, Chen Y, Mei J, Wei J, Chen X,Lei G, Zeng C.

Sci Adv.2025 Jul 25;11(30):eadv4238. doi: 10.1126/sciadv.adv4238.Epub 2025 Jul 25.

https://pubmed.ncbi.nlm.nih.gov/40712009/

1208. The rise of China's pharmaceutical industry from2015-2024: a decade of innovation

Liu S, Hu H, Ge C, Yuan S, Jiang J, Chen X.

Nat Rev Drug Discov.2025 Oct;24(10):738-739. doi: 10.1038/d41573-025-00102-1.

https://pubmed.ncbi.nlm.nih.gov/40696202/

1207. A Mesoporous Calcium Peroxide Nanocuboidwith High Tumor Accumulation Across Biological Barriers for High Efficacy TumorTherapy

Fan Q, Wang M, Lin J, Huang Y, Yang J, Zhu J, Ren B,Sun L, Li Z, Liu A, Xiong W, Wei Z, Huang L, Yan C, Wen G, Chen Z, Chen X, ShenZ.

Adv Sci (Weinh). 2025 Oct;12(39):e10778. doi: 10.1002/advs.202510778. Epub2025 Jul 20.

https://pubmed.ncbi.nlm.nih.gov/40685683/

1206.Metal-PhenolicOuter Membrane Vesicles for Cancer Radioimmunotherapy

Zhao C, Pan Y, Cao L, TangY, Chen X, Zhao X, Rao L.

J Am Chem Soc.2025 Jul 30;147(30):26195-26207. doi:10.1021/jacs.5c02774. Epub 2025 Jul 17.

https://pubmed.ncbi.nlm.nih.gov/40676848/

1205. Establishment of an indirect ELISA forfeline coronavirus antibody detection and serotype discrimination

Lu X, Hu Y, Chen X, Shen Y.

J Virol Methods.2025 Dec;338:115224. doi: 10.1016/j.jviromet.2025.115224.Epub 2025 Jul 13.

https://pubmed.ncbi.nlm.nih.gov/40664264/

1204. Microenvironment responsive nanoplatform fortargeted removal of cholesterol and reshaping inflammatory microenvironment inatherosclerotic plaques

Shen L, Jiang C, Song J, Bi Y, Chen W, Lu C, Chen M,Lv L, Yu R, Zou J, Zhao Z, Chen X, Ji J.

J Control Release.2025 Sep 10;385:114000. doi:10.1016/j.jconrel.2025.114000. Epub 2025 Jul 6.

https://pubmed.ncbi.nlm.nih.gov/40628350/

1203.Optogeneticengineering of lipid droplet spatial organization for tumor suppression

Bai Q, Shao X, Xia Q,Yang S, GaoY, Sun K, Li J, WangX, Tian Z, Chen X, Zhao J, Diao J, Chen Q.

Trends Biotechnol.2025 Jul 1:S0167-7799(25)00217-3. doi:10.1016/j.tibtech.2025.06.002. Online ahead of print.

https://pubmed.ncbi.nlm.nih.gov/40603219/

1202.Smartultra-long-lasting sequentially triggerable and artfully implantable nozzlesystem for on-demand drug delivery for chronotherapy

Zeng Q, Gong Y, Jiao W, Xu J, Chen X, Xu R, Liu Y,Liang X, Li G, Liu J, He L, Li W, Zhang X, Chen X, Chen W.

Sci Adv. 2025 Jun 27;11(26):eadv8734. doi: 10.1126/sciadv.adv8734.Epub 2025 Jun 25.

https://pubmed.ncbi.nlm.nih.gov/40561013/

 

1201. Genistein Exudation Drives Spatial RootAllocation and Heterogeneous Microbial Communities to Enhance PhosphorusAcquisition in Soybean-Maize Intercropping

Zhang B, Jiang H, Zheng G, Zhang Z, Wang T, Chen Q,Chen X, Lu X, Liang C,Tian J.

Plant Cell Environ. 2025 Oct;48(10):7297-7312. doi: 10.1111/pce.70020. Epub2025 Jun 22.

https://pubmed.ncbi.nlm.nih.gov/40545709/

1200.High temperatures and microplastic enhancedinorganic phosphorus mineralization and phoD-harboring bacterial abundance inpaddy soil

Afzal M, Tan X, Fang ML, Jin W, Liang Q, Wang X, ChenX, Zhang X,Tan Z.

Ecotoxicol Environ Saf. 2025 Sep 1;302:118495. doi:10.1016/j.ecoenv.2025.118495. Epub 2025 Jun 17.

https://pubmed.ncbi.nlm.nih.gov/40532605/

1199. Synthetic biology-driven induction of matureTLS formation enhances antitumor immunity in colorectal cancer

Mi Z, Chen J, Zhang Z, Liu J, Lei Y,Tan H, Li W, ChenX, Rong P.

Sci Transl Med.2025 Jun 18;17(803):eado8395. doi:10.1126/scitranslmed.ado8395. Epub 2025 Jun 18.

https://pubmed.ncbi.nlm.nih.gov/40531967/

1198. The association between physical activityand lung function in adolescents: a cross-sectional NHANES study

Chen X, Ma J, Dong L, Chen Y, Chen K.

Front Med (Lausanne). 2025 Jun 3;12:1538221. doi: 10.3389/fmed.2025.1538221.eCollection 2025.

https://pubmed.ncbi.nlm.nih.gov/40529127/

1197. A nanovaccine targeting cancer stem cellsand bulk cancer cells for postoperative cancer immunotherapy

You Q, Wu G, Li H, Liu J, Cao F, Ding L, Liang F,Zhou B, Ma L, Zhu L, Wang C,YangY, Chen X.

Nat Nanotechnol. 2025 Sep;20(9):1298-1311. doi:10.1038/s41565-025-01952-x. Epub 2025 Jun 16.

https://pubmed.ncbi.nlm.nih.gov/40523938/

1196. Biomineral tablets for long-acting IL-2immunotherapy

Liu J, Chen X.

Nat Cancer.2025 Aug;6(8):1304-1306. doi: 10.1038/s43018-025-00951-0.

https://pubmed.ncbi.nlm.nih.gov/40494939/

1195. Unconventional PROTACs for Targeted ProteinDegradation in Cancer Therapy

Zhang X, Song Z, Zhang X, Zou J,Yu G, Chen X, Wang S.

Angew Chem Int Ed Engl. 2025 Jul 28;64(31):e202507702. doi:10.1002/anie.202507702. Epub 2025 Jun 18.

https://pubmed.ncbi.nlm.nih.gov/40492592/

1194. Rheumatoid arthritis and chronic obstructivepulmonary disease in US adults: a cross-sectional analysis

Mi P, Wang H, Fan G, Chen S, Chen X, Cao X, Feng H.

Front Med (Lausanne).2025 May 23;12:1577180. doi: 10.3389/fmed.2025.1577180.eCollection 2025.

https://pubmed.ncbi.nlm.nih.gov/40486196/

1193.Humaninduced pluripotent stem cell derived nanovesicles for cardiomyocyte protectionand proliferation

Wei Y, Geng X, You Q, Zhang Y, Cao F, Narayanan G,Nguyen T, Chen X, Zhang J, Ye L.

Bioact Mater. 2025 May 2;50:585-602. doi:10.1016/j.bioactmat.2025.04.017. eCollection 2025 Aug.

https://pubmed.ncbi.nlm.nih.gov/40453695/

1192.Self-AssembledFluorescent Peptide Nanoprobes for Disease Diagnosis

Wang R, Xi T, Li K, Wang C, Gao X,Yang H, Zou J, ChenX, Sun L.

Small Methods. 2025 Jun 1:e2500518. doi: 10.1002/smtd.202500518. Onlineahead of print.

https://pubmed.ncbi.nlm.nih.gov/40451981/

1191. A multi-dimensional comparative study of505(b)(2) NDAs approved by FDA and Class 2 NDAs approved by NMPA from 2017 to2023: Uncovering trends, characteristics, and regulation of modified new drugs

Fu L, Dong S, Xie R, Jia G, Zhao N, Xiang Q, Ji X,Zhao X, Chen X, Ma L, Cui Y.

Regul Toxicol Pharmacol. 2025 Nov;162:105864. doi:10.1016/j.yrtph.2025.105864. Epub 2025 May 27.

https://pubmed.ncbi.nlm.nih.gov/40441284/

1190. Patient reported outcomes in the FDAapproved drugs for systemic rheumatic diseases (2013-2024)

Xie Y, Liu Y, Qin Y, Yin G, Chen X, Xie Q.

Health Qual Life Outcomes. 2025 May 28;23(1):52. doi:10.1186/s12955-025-02386-8.

https://pubmed.ncbi.nlm.nih.gov/40437506/

1189. Self-Promoting Targeted Delivery ofEpigenetic Immunostimulants to Activate Breast Cancer Immunity via HDACsDownregulation and PD-L1 Upregulation

Chen X, Lu L, Liang Z, Yu B, Shao Z, Li J, Cen Y, LiuY, Li S, Chen X.

Angew Chem Int Ed Engl.2025 Jul 28;64(31):e202502120. doi:10.1002/anie.202502120. Epub 2025 Jun 11.

https://pubmed.ncbi.nlm.nih.gov/40423498/

1188. Nano-selenium mitigates arsenate toxicity insoybean roots by modulating phenylalanine and salicylic acid pathways

Zeeshan M, Khan AH, Salam A, Hu Y, Iqbal A, Hou R,Umar AW, Wu F, Chen X, Zhang Z.

BMC Plant Biol.2025 May 26;25(1):699. doi: 10.1186/s12870-025-06726-0.

https://pubmed.ncbi.nlm.nih.gov/40414885/

1187. Au(6)Cu(2) Clusters with High ElectronAffinity and Oxygen-Mimetic Properties for Hypoxic Tumor Radiosensitization

Zhao X, Han J, Liu J, Wang ZY, Chen X, Zang SQ.

Angew Chem Int Ed Engl.2025 Jul 21;64(30):e202504524. doi:10.1002/anie.202504524. Epub 2025 May 24.

https://pubmed.ncbi.nlm.nih.gov/40387628/

1186. An Environmentally Responsive MolecularEngineering Framework for Subcellular Drug Translocalization

Fang G, Liu D, Bai Q, Shao X, Liu Z, Yao Q, Yuan Y,Zeng K, Chen X, Chen X, Chen Q.

Adv Mater.2025 Jul;37(29):e2503220. doi: 10.1002/adma.202503220.Epub 2025 May 13.

https://pubmed.ncbi.nlm.nih.gov/40357889/

1185.Tumormicroenvironment responsive nano-PROTAC for BRD4 degradation enhanced cancerphoto[1]immunotherapy

Li Z, Ren G, Wang X, Li X, Ding L, Zhu J, Zhang Y,Zhang C, Zou J, Chen X.

Biomaterials.2025 Nov;322:123387. doi:10.1016/j.biomaterials.2025.123387. Epub 2025 May 7.

https://pubmed.ncbi.nlm.nih.gov/40344878/

1184. Interspecific Mating Is Trivial andAsymmetrical Between Two Destructive Anoplophora Beetles

Xu T, Wang W, Chen X, Ma J, Chen R, Sun X, Yang Y, LiG, Deng Y, Hao D.

Insects. 2025 Mar 27;16(4):352. doi: 10.3390/insects16040352.

https://pubmed.ncbi.nlm.nih.gov/40332794/

1183.Self-promotedtumor-targeting nanomedicine activates STING-driven antitumor immunity viaphotodynamic DNA damage and PARP inhibition

Yu B, Zhang W, Shao Z, Chen X, Cen Y, Liu Y, Chen Y,Li X, Liang Z, Li S, Chen X.

Chem Sci. 2025 May 1;16(22):9756-9765. doi: 10.1039/d5sc01953b.eCollection 2025 Jun 4.

https://pubmed.ncbi.nlm.nih.gov/40321187/

1182.BioinspiredClaw-Engaged Adhesive Microparticles Armed with γGC Alleviate UlcerativeColitis via Targeted Suppression of Macrophage Ferroptosis

Wang R, Zhu J, Zhou J, Li J, Wang M, Wu Y, Zhao D,Chen X, Chen X, Wang Y, Zou J.

Adv Sci (Weinh).2025 Aug;12(30):e2503903. doi: 10.1002/advs.202503903.Epub 2025 Apr 29.

https://pubmed.ncbi.nlm.nih.gov/40298904/

1181. Permanent Efferocytosis Prevention byTerminating MerTK Recycle on Tumor-Associated Macrophages for CancerImmunotherapy

Huang P, Liu Y, Zhao C, Wang C, Wang L, Luo M, WangW, Shan W, Liu X, Li B, Wang Z, Deng H, Chen X.

J Am Chem Soc.2025 May 7;147(18):15901-15914. doi:10.1021/jacs.5c05640. Epub 2025 Apr 28.

https://pubmed.ncbi.nlm.nih.gov/40294287/

1180. Comparison of Al 18 F-NOTA-FAPI-74 and 18F-FDG PET/CT in the Evaluation and Staging of Hepatobiliary Malignancies : ASingle-center Prospective Study

Hou G, Cheng X, Jiang Y, Yang Y, Chen B, Huang Z, LiZ, Zhou A, Chen X, Zheng R, Zhao H, Zhang J, Wang X.

Clin Nucl Med. 2025 Jul 1;50(7):612-622. doi:10.1097/RLU.0000000000005889. Epub 2025 Apr 24.

https://pubmed.ncbi.nlm.nih.gov/40279677/

1179. Ruthenium Single-Atom Nanozyme DrivenSonosensitizer with Oxygen Vacancies Enhances Electron[1]HoleSeparation Efficacy and Remodels Tumor Microenvironment forSonodynamic-AmplifiedFerroptosis

Zhu Y, Wang D, Du C, Wu T, Wei P, Zheng H, Li G,Zheng S, Su L,Yan L, Hu Y, Wang H, Lin L, Ding C, Chen X.

Adv Sci (Weinh). 2025 Jun;12(22):e2416997. doi: 10.1002/advs.202416997.Epub 2025 Apr 25.

https://pubmed.ncbi.nlm.nih.gov/40279631/

1178. Amplifying X-ray-Induced Charge TransferFacilitates Direct Sensitization of Photosensitizers in Radiotherapy

Zhang D, Chen Q, Zhang J, Xing X, Zhou Y, Ou X, DaiS, Chen Q, Liu X, Chen X, Zeng Y.

ACS Nano. 2025 May 6;19(17):16775-16793. doi:10.1021/acsnano.5c01506. Epub 2025 Apr 25.

https://pubmed.ncbi.nlm.nih.gov/40277128/

1177. Unlocking the Potential of Disulfidptosis:Nanotechnology-Driven Strategies for Advanced Cancer Therapy

Zhen W, Zhao T, Chen X, Zhang J.

Small.2025 Jun;21(23):e2500880. doi: 10.1002/smll.202500880.Epub 2025 Apr 24.

https://pubmed.ncbi.nlm.nih.gov/40269657/

1176. Nanotherapeutic Wee1 Inhibition SensitizesTumor Ferroptosis to Promote Cancer Immunotherapy and Abscopal Effect

Zhou P, Huang R, Cheng Y, Yang Y, Qian D, Ming X,Wang AZ, Chen X, Min Y.

ACS Nano.2025 May 6;19(17):16307-16326. doi:10.1021/acsnano.4c13218. Epub 2025 Apr 22.

https://pubmed.ncbi.nlm.nih.gov/40263774/

1175. Visual recombinase aided amplificationtechnology for detecting feline coronavirus

Lu X, Cao Y, Zhang P, Chen X, Irwin DM, Shen Y.

Vet J.2025 Aug;312:106356. doi: 10.1016/j.tvjl.2025.106356.Epub 2025 Apr 12.

https://pubmed.ncbi.nlm.nih.gov/40228788/

1174. PSMA-targeted radioligand therapy with[(177)Lu]Lu-LNC1011 for metastatic castration-resistant prostate cancer: apilot study

Hou L, Wang Y, Fu H, Chen L, Yu C, Chen X, Zhang J.

Eur J Nucl Med Mol Imaging.2025 Sep;52(11):4033-4043.doi:10.1007/s00259-025-07245-8. Epub 2025 Apr 10.

https://pubmed.ncbi.nlm.nih.gov/40208314/

1173. Molecular Imaging of B7-H3-TargetingBispecific T Cell-Engaging Antibody MGD009 in Glioblastoma Models

Liu P, Ding H, Jia S, Pang Y, Li C, Zhao T,Skudder-Hill L, Wang J, Chen H, Zhao X, Chen X, Zhang J.

ACS Appl Mater Interfaces. 2025 Apr 16;17(15):22384-22393. doi:10.1021/acsami.5c01451. Epub 2025 Apr 4.

https://pubmed.ncbi.nlm.nih.gov/40183579/

1172. Safety, dosimetry, and efficacy of anoptimized long-acting somatostatin analog for peptide receptor radionuclidetherapy in metastatic neuroendocrine tumors: From preclinical testing tofirst-in-human study

Guo W, Wen X, Chen Y, Zhao T, Liu J,Tao Y, Fu H, WangH, Xu W, Pang Y, Zhao L, Huang J, Xu P, Guo Z, Miao W, Zhang J, Chen X, Chen H.

Acta Pharm Sin B. 2025 Feb;15(2):707-721. doi: 10.1016/j.apsb.2024.05.022.Epub 2024 May 29.

 

1171. Role of genetic variants and DNA methylationof lipid metabolism-related genes in metabolic dysfunction-associated steatoticliver disease

Wang JJ, Chen XY, Zhang YR, Shen Y, Zhu ML, Zhang J,Zhang JJ.

Front Physiol. 2025 Mar 17;16:1562848. doi: 10.3389/fphys.2025.1562848.eCollection 2025.

https://pubmed.ncbi.nlm.nih.gov/40166716/

1170. Optothermal-Stimulated PersistentLuminescence Imaging and Therapy (OSPLIT)

Pei P, Chen Y, Chen X, Zhang F, Liu X, Wang JW.

Adv Mater.2025 May;37(21):e2500769. doi: 10.1002/adma.202500769.Epub 2025 Mar 31.

https://pubmed.ncbi.nlm.nih.gov/40159881/

1169. Emerging patterns in nanoparticle-basedtherapeutic approaches for rheumatoid arthritis: A comprehensive bibliometricand visual analysis spanning two decades

Xie S, Liao P, Mi S, Song L, Chen X.

Open Life Sci.2025 Mar 21;20(1):20251071. doi: 10.1515/biol-2025-1071.eCollection 2025.

https://pubmed.ncbi.nlm.nih.gov/40129468/

1168. Bottom-Up Selective Growth of UltralongOrganic Phosphorescence Nanocrystals with Optimized Crystal Forms for In VivoOptical Imaging

Chen J, Wei Z, Shan Y, Chen S, Wu Z, Liu S, Zhang J,Chen X, Liu B.

Adv Mater.2025 May;37(19):e2418795. doi: 10.1002/adma.202418795.Epub 2025 Mar 24.

https://pubmed.ncbi.nlm.nih.gov/40129078/

1167. Dansylated Amino Acid-Modified Long-ActingPSMA Derivatives (68)Ga/(177)Lu-LNC1011 as Prostate Cancer Theranostics

Yang H, Wang J, Wen X, Guo H, Jakobsson V, Zhao T,Zeng F, Shen H, Zhang H, Liu X, Qin Y, Li X, Xiong H, Zhou Z, Zhang J, Chen X.

J Nucl Med. 2025 May 1;66(5):739-747. doi:10.2967/jnumed.124.268959.

https://pubmed.ncbi.nlm.nih.gov/40113222/

1166. TLR4 mediates glucolipotoxicity-inducedmitochondrial dysfunction in osteoblasts by enhancing NLRP3- MAVS expressionand interaction

Shen X, Chen X, Zhong S, Zhang Y, Zhou X, Lan C, LinJ, Zheng L, Yan S.

Int Immunopharmacol. 2025 Apr 24;153:114438. doi:10.1016/j.intimp.2025.114438. Epub 2025 Mar 17.

https://pubmed.ncbi.nlm.nih.gov/40101421/

1165. Ultrasound-Activated Theranostic Materialsand Their Bioapplications

Zhu K, Wang J, Wang Z, Chen Q, Song J, Chen X.

Angew Chem Int Ed Engl. 2025 May 26;64(22):e202422278. doi:10.1002/anie.202422278. Epub 2025 Apr 3.

https://pubmed.ncbi.nlm.nih.gov/40091509/

1164. 177Lu-LNC1004 Radioligand Therapy inPatients with End-stage Metastatic Cancers: A Single-Center, Single-Arm, PhaseII Study

Fu H, Huang J, Zhao L, Chen Y, Xu W, Cai J,Yu L, PangY, Guo W, Su B, Sun L, Wu H, Zhang J, Chen X, Chen H.

Clin Cancer Res. 2025 Apr 14;31(8):1415-1426. doi:10.1158/1078-0432.CCR-24-3918.

https://pubmed.ncbi.nlm.nih.gov/40084923/

1163. Comparison of [(68)Ga]Ga-FibroblastActivation Protein Inhibitor-04 and [(18)F]FDG PET Imaging for Solitary FibrousTumor and Preliminary Application of FAP-Targeted Radiopharmaceutical Therapy

Wang R, Wang J, Xiang J, Sui H, Li L, Jia C, Peng X,Chen X, Zhu Z, Zhang J.

J Nucl Med.2025 Apr 1;66(4):585-591. doi: 10.2967/jnumed.124.268258.

https://pubmed.ncbi.nlm.nih.gov/40049742/

1162. Simultaneous Reversal of T Lymphocytes andCancer Cells Metabolism Via a Biomimetic Heavy-Atom[1]FreePhotosensitizers-Based Combination Therapies to Boost Cancer Photoimmunotherapy

Zhang Y, Wu X, Wang K,Tang Y, Lu X, Sun F,Tang H,Chen X, Ning S.

Adv Sci (Weinh). 2025 Apr;12(16):e2416143. doi: 10.1002/advs.202416143.Epub 2025 Mar 5.

https://pubmed.ncbi.nlm.nih.gov/40042072/

1161. Self-Accelerated Nanoregulators for PositiveFeedback Ferroptosis-Immunotherapy

Zhang X, Zhang X, Fan Q, Li J, Jia S, Chen X, Wang S.

Small.2025 Apr;21(14):e2408156. doi: 10.1002/smll.202408156.Epub 2025 Mar 3.

https://pubmed.ncbi.nlm.nih.gov/40026025/

1160. Genetically reprogrammed exosomes for cancerimmunotherapy

Gu W,Tian Q, Xie T, Chen X.

Mol Ther. 2025 Mar 5;33(3):837-839. doi:10.1016/j.ymthe.2025.02.009. Epub 2025 Feb 25.

https://pubmed.ncbi.nlm.nih.gov/40010337/

1159. Development of [(225)Ac]Ac-LNC1011 fortargeted alpha-radionuclide therapy of prostate cancer

Wen X, Zhao T, Yang H, Shi M, Wee XJ, Fu J, Lin M,Zhang Z, Zou M, Green D, Wu X, Chen X, Zhang J.

Eur J Nucl Med Mol Imaging. 2025 Jul;52(8):2841-2855. doi:10.1007/s00259-025-07155-9. Epub 2025 Feb 24.

https://pubmed.ncbi.nlm.nih.gov/39992401/

1158. Pyridinium Rotor Strategy toward a RobustPhotothermal Agent for STING Activation and Multimodal Image-GuidedImmunotherapy for Triple-Negative Breast Cancer

Ning S, Shang guan P, Zhu X, Ou X, Wang K, Suo M,Shen H, Lu X, Wei X, Zhang T, Chen X,Tang BZ.

J Am Chem Soc.2025 Mar 5;147(9):7433-7444. doi: 10.1021/jacs.4c15534.Epub 2025 Feb 20.

https://pubmed.ncbi.nlm.nih.gov/39977833/

1157. Remodeling tumor microenvironment usingprodrug nMOFs for synergistic cancer therapy

Dong J, Ding J, Luo S, Li R, Wang Y, Xiao B, Pei Y,Chen X, Sun W, Pei Z.

J Nanobiotechnology.2025 Feb 19;23(1):123. doi: 10.1186/s12951-025-03202-7.

https://pubmed.ncbi.nlm.nih.gov/39972341/

1156.FibroblastActivation Protein Acts as a Biomarker for Monitoring ECM Remodeling DuringAortic Aneurysm via (68)Ga-FAPI-04 PET Imaging

Hu C,Tan H, Zhang Y, Cao G, Wu C, Lin P, Qiu S, Mo F,Wang E, Li S,Yuan T, Li Z, Fu W, Cheng D, Lai H, Chen X, Wang L.

Adv Sci (Weinh).2025 Apr;12(14):e2411152. doi: 10.1002/advs.202411152.Epub 2025 Feb 14.

https://pubmed.ncbi.nlm.nih.gov/39950910/

1155.Internationalapprovals of cilta-cel: a lens on CAR T cell regulation

Ge C, Yin C, Chen X.

Nat Rev Clin Oncol.2025 Apr;22(4):233-234. doi: 10.1038/s41571-025-00996-1.

https://pubmed.ncbi.nlm.nih.gov/39915676/

1154.Contrastingcytotoxic and regulatory T cell responses underlying distinct clinical outcomesto anti-PD-1 plus lenvatinib therapy in cancer

Guo X, Nie H, Zhang W, Li J, Ge J, Xie B, Hu W, Zhu Y,Zhong N, Zhang X, Zhao X, Wang X, Sun Q, Wei K, Chen X, Ni L, Zhang T, Lu S,Zhang L, Dong C.

Cancer Cell. 2025 Feb 10;43(2):248-268.e9. doi:10.1016/j.ccell.2025.01.001. Epub 2025 Jan 30.

https://pubmed.ncbi.nlm.nih.gov/39889705/

1153. Breaking frontiers with multidisciplinarycancer research

Caldas C, Chen X, Ding L, Kather JN, Scaltriti M.

Nat Cancer. 2025 Jan;6(1):13-15. doi: 10.1038/s43018-024-00875-1.

https://pubmed.ncbi.nlm.nih.gov/39885365/

1152. CaLu(2)Sc(2)Al(2)SiO(12):Ce(3+) GreenPhosphors for High-Quality White LEDs

Chen X, Huang X.

Inorg Chem.2025 Feb 10;64(5):2518-2528. doi:10.1021/acs.inorgchem.4c05104. Epub 2025 Jan 29.

https://pubmed.ncbi.nlm.nih.gov/39879654/

1151. Disruption of midgut homeostasis bymicroplastics in Spodoptera frugiperda: Insights into inflammatory andoxidative mechanisms

Fan Z, Khan MM, Wang K, Li Y, Jin F, Peng J, Chen X,Kong W, Lv X, Chen X, Qiu B, Wang X.

J Hazard Mater. 2025 Apr 5;487:137262. doi:10.1016/j.jhazmat.2025.137262. Epub 2025 Jan 16.

https://pubmed.ncbi.nlm.nih.gov/39842122/

1150. Gastrin-Releasing Peptide Receptor TargetingPET/CT With 68 Ga-NOTA-RM26 in the Assessment of Glioma and CombinedMultiregional Biopsies

Wang R, Li Y, Li Z, Wang J, Li L, Xiang J, Jia C,Peng X, Wang Y, Ma W, Wang L, Jia W, Chen X, Li D, Zhu Z, Zhang J.

Clin Nucl Med.2025 Apr 1;50(4):316-323. doi:10.1097/RLU.0000000000005651. Epub 2025 Jan 14.

https://pubmed.ncbi.nlm.nih.gov/39806560/

1149. Preclinical and First-in-Human Study of aCompact Radionuclide Labeled Self-Assembly Nanomedicine forChemo-Radio-Theranostics of Cancer

Xiong H, Wang R, Zhang H, Zhang Q, Qin Y, Du C, ZhangX, Ye J, Shi C, Shen H, Zhu Z, Zhou Z, Chen X, Zhang J.

ACS Nano.2025 Jan 28;19(3):3953-3965. doi:10.1021/acsnano.4c18489. Epub 2025 Jan 13.

https://pubmed.ncbi.nlm.nih.gov/39806279/

1148.ASmall-Molecule Drug for the Self-Checking of Mitophagy

GaoY, Bai Q, RenY, Shao X, Zhang M, Wu L, Lewis SE,James TD, Chen X, Chen Q.

Angew Chem Int Ed Engl. 2025 Mar 3;64(10):e202421269. doi:10.1002/anie.202421269. Epub 2025 Jan 22.

https://pubmed.ncbi.nlm.nih.gov/39800659/

1147. FAP-targeted radioligand therapy with(68)Ga/(177)Lu-DOTA-2P(FAPI)(2) enhance immunogenicity and synergize with PD-L1inhibitors for improved antitumor efficacy

Chen J, Zhou Y, Pang Y, Fu K, Luo Q, Sun L, Wu H, LinQ, Su G, Chen X, Zhao L, Chen H.

J Immunother Cancer.2025 Jan 11;13(1):e010212. doi: 10.1136/jitc-2024-010212.

https://pubmed.ncbi.nlm.nih.gov/39800373/

1146. Sequential Targeting ChondroitinSulfate-Bilirubin Nanomedicine Attenuates Osteoarthritis via ReprogrammingLipid Metabolism in M1 Macrophages

Deng C, Xiao Y, Zhao X, Li H, ChenY, Ai K, Jiang T,Wei J, Chen X, Lei G, Zeng C.

Adv Sci (Weinh). 2025 Mar;12(9):e2411911. doi: 10.1002/advs.202411911.Epub 2025 Jan 10.

https://pubmed.ncbi.nlm.nih.gov/39792653/

1145. One-Pot Synthesis of Oxygen Vacancy-RichAmorphous/Crystalline Heterophase CaWO(4) Nanoparticles for EnhancedRadiodynamic-Immunotherapy

Peng S, Chen Z, Wang J, Yu M, Niu X, Cui T, Ao R, CaiH, Huang H, Lin L, Chen X, Yang H.

Adv Sci (Weinh). 2025 Feb;12(7):e2409551. doi: 10.1002/advs.202409551.Epub 2024 Dec 27.

https://pubmed.ncbi.nlm.nih.gov/39731356/

1144. STING-Activating Polymers Boost LymphaticDelivery of mRNA Vaccine to Potentiate Cancer Immunotherapy

Zhang M, Wang Y, Li B,Yang B, Zhao M, Li B, Liu J, HuY, Wu Z, Ong Y, Han X, Ding L, Zhu K, Li J, Luo M, Chen S, Peng L,

Zhang L, Chen X, Ni Q.

Adv Mater. 2025 Mar;37(10):e2412654. doi: 10.1002/adma.202412654.Epub 2024 Dec 23.

https://pubmed.ncbi.nlm.nih.gov/39713955/

1143. Metal-based smart nanosystems in cancerimmunotherapy

Luo Y, He X, Du Q, Xu L, Xu J, Wang J, Zhang W, ZhongY, Guo D, Liu Y, Chen X.

Exploration (Beijing). 2024 Mar 22;4(6):20230134. doi:10.1002/EXP.20230134. eCollection 2024 Dec.

https://pubmed.ncbi.nlm.nih.gov/39713201/

1142. X-ray-activated nanoscintillators integratedwith tumor-associated neutrophils polarization for improved radiotherapy inmetastatic colorectal cancer

Li H, Zeng J, You Q, Zhang M, Shi Y, Yang X, Gu W,Liu Y, Hu N, Wang Y, Chen X, Mu J.

Biomaterials. 2025 May;316:123031. doi:10.1016/j.biomaterials.2024.123031. Epub 2024 Dec 16.

https://pubmed.ncbi.nlm.nih.gov/39709848/

 

1148.ASmall-Molecule Drug for the Self-Checking of Mitophagy

GaoY, Bai Q, RenY, Shao X, Zhang M, Wu L, Lewis SE,James TD, Chen X, Chen Q.

Angew Chem Int Ed Engl. 2025 Mar 3;64(10):e202421269. doi:10.1002/anie.202421269. Epub 2025 Jan 22.

https://pubmed.ncbi.nlm.nih.gov/39800659/

1147. FAP-targeted radioligand therapy with(68)Ga/(177)Lu-DOTA-2P(FAPI)(2) enhance immunogenicity and synergize with PD-L1inhibitors for improved antitumor efficacy

Chen J, Zhou Y, Pang Y, Fu K, Luo Q, Sun L, Wu H, LinQ, Su G, Chen X, Zhao L, Chen H.

J Immunother Cancer.2025 Jan 11;13(1):e010212. doi: 10.1136/jitc-2024-010212.

https://pubmed.ncbi.nlm.nih.gov/39800373/

1146. Sequential Targeting ChondroitinSulfate-Bilirubin Nanomedicine Attenuates Osteoarthritis via ReprogrammingLipid Metabolism in M1 Macrophages

Deng C, Xiao Y, Zhao X, Li H, ChenY, Ai K, Jiang T,Wei J, Chen X, Lei G, Zeng C.

Adv Sci (Weinh). 2025 Mar;12(9):e2411911. doi: 10.1002/advs.202411911.Epub 2025 Jan 10.

https://pubmed.ncbi.nlm.nih.gov/39792653/

1145. One-Pot Synthesis of Oxygen Vacancy-RichAmorphous/Crystalline Heterophase CaWO(4) Nanoparticles for EnhancedRadiodynamic-Immunotherapy

Peng S, Chen Z, Wang J, Yu M, Niu X, Cui T, Ao R, CaiH, Huang H, Lin L, Chen X, Yang H.

Adv Sci (Weinh). 2025 Feb;12(7):e2409551. doi: 10.1002/advs.202409551.Epub 2024 Dec 27.

https://pubmed.ncbi.nlm.nih.gov/39731356/

1144. STING-activating Polymers Boost LymphaticDelivery of mRNA Vaccine to Potentiate Cancer Immunotherapy

Zhang M, Wang Y, Li B,Yang B, Zhao M, Li B, Liu J, HuY, Wu Z, Ong Y, Han X, Ding L, Zhu K, Li J, Luo M, Chen S, Peng L,

Zhang L, Chen X, Ni Q.

Adv Mater. 2025 Mar;37(10):e2412654. doi: 10.1002/adma.202412654.Epub 2024 Dec 23.

https://pubmed.ncbi.nlm.nih.gov/39713955/

1143. Metal-based smart nanosystems in cancerimmunotherapy

Luo Y, He X, Du Q, Xu L, Xu J, Wang J, Zhang W, ZhongY, Guo D, Liu Y, Chen X.

Exploration (Beijing). 2024 Mar 22;4(6):20230134. doi:10.1002/EXP.20230134. eCollection 2024 Dec.

https://pubmed.ncbi.nlm.nih.gov/39713201/

1142. X-ray-activated nanoscintillators integratedwith tumor-associated neutrophils polarization for improved radiotherapy inmetastatic colorectal cancer

Li H, Zeng J, You Q, Zhang M, Shi Y, Yang X, Gu W,Liu Y, Hu N, Wang Y, Chen X, Mu J.

Biomaterials. 2025 May;316:123031. doi:10.1016/j.biomaterials.2024.123031. Epub 2024 Dec 16.

https://pubmed.ncbi.nlm.nih.gov/39709848/

1141. One-Pot Synthesis of Oxygen Vacancy-RichAmorphous/Crystalline Heterophase CaWO4 Nanoparticles Immunotherapy.

Adv Sci (Weinh). 2024 Dec 27:e2409551. doi: 10.1002/advs.202409551.

Peng S, Chen Z, Wang J, Yu M, Niu X, Cui T, Ao R, CaiH, Huang H, Lin L, Chen X, Yang H.

https://pubmed.ncbi.nlm.nih.gov/39731356/

1140. STING-Activating Polymers Boost LymphaticDelivery of mRNA Vaccine to Potentiate Cancer Immunothe

Adv Mater. 2024 Dec 23:e2412654.

Zhang M, WangY, Li B, Yang B, Zhao M, Li B, Liu J, HuY, Wu Z, Ong Y, Han X, Ding L, Zhu K, Li J, Luo M, Chen S, Peng L

https://pubmed.ncbi.nlm.nih.gov/39713955/

1139. Metal-based smart nanosystems in cancerimmunotherapy.

Exploration (Beijing). 2024 Mar 22;4(6):20230134.

Luo Y, He X, Du Q, Xu L, Xu J, Wang J, Zhang W, ZhongY, Guo D, Liu Y, Chen X.

https://pubmed.ncbi.nlm.nih.gov/39713201/

1138. Cascade-Activatable Nanoprodrug SystemAugments Sonochemotherapy of Bladder Cancer.

ACS Nano. 2024 Dec 17. doi: 10.1021/acsnano.4c12967.

Hou DY, You Q, Zhang P, Li XP, Wu JC, Wang Y, You HH,Lv MY, Wu G, Liu X, Guo P, Cheng DB, Chen X, Xu W.

https://pubmed.ncbi.nlm.nih.gov/39686741/

1137. Spatiotemporal Nano-Regulator UnleashesAnti-Tumor Immunity by Overcoming Dendritic Cell Tolerance Draining LymphNodes.

Adv Mater. 2024 Dec 11:e2412141.

Wang R, Li H, He S, Feng Y, Liu C, Hao K, Zhou D,Chen X,Tian H.

https://doi.org/10.1002/adma.202412141/

1136. [18F]AlF-NOTA-pentixather PET/CT of CXCR4 inpatients with suspected primary hyperaldosteronism

Theranostics. 2024 Oct 28;14(19):7281-7291

He L, Yang Y, Cao X, Zhu X, Liu N, Chen X, Zhang J,Zhang W.

https://pubmed.ncbi.nlm.nih.gov/39659571/

1135. NIR-II Imaging for Tracking theSpatiotemporal Immune Microenvironment in Atherosclerotic Plaques.

ACS Nano. 2024 Dec 17;18(50):34171-34185

Shen L, Chen M, Su Y, Bi Y, Shu G, Chen W, Lu C, ZhaoZ, Lv L, Zou J, Chen X, Ji J.

https://pubmed.ncbi.nlm.nih.gov/39630481/

1134. Late-stage (radio)fluorination of alkylphosphonates via electrophilic activation.

Nat Commun. 2024 Nov 28;15(1):10338.

Zhang K, Feng W, Mou Z, Zhang L, Ma M, Zhao Z, Liu X,Chen X, Li Z.

https://pubmed.ncbi.nlm.nih.gov/39609392/

1133.Comparative Study of [18F]AlF-LNC1007,[18F]FDG, and [18F]AlF-NOTA-FAPI-04 PET/CT in Breast Cance Exploration andAnalytical Insight.

ACS Appl Mater Interfaces. 2024 Dec 11;16(49):67523-67531.

Gao H, Chen J, Yang Z, Zhu Z, He L, Zhang W, Chen X,Zhang J.

https://pubmed.ncbi.nlm.nih.gov/39607746/

1132. Chemical Synthesis and Multihybridization ofSmall-Sized Hollow Mesoporous Organosilica Nanoparticl

Acc Chem Res. 2024 Dec 17;57(24):3465-3477

Huang Y, Zhang C, Zhang L, Chen X, Fan W.

https://pubmed.ncbi.nlm.nih.gov/39576957/

1131. Pulmonary delivery of dual-targetednanoparticles improves tumor accumulation and cancer cell targetin interceptionin orthotopic lung tumors.

Biomaterials. 2024 Nov 8;315:122955. doi:10.1016/j.biomaterials.2024.122955.

Ge D, Ma S, Sun T, Li Y, Wei J, Wang C, Chen X, Liao Y.

https://www.sciencedirect.com/science/article/abs/pii/S0142961224004903?via%3Dihub

1130. Inflammasome-Activating Nanovaccine forCancer Immunotherapy.

Cancer Res. 2024 Nov 15;84(22):3709-3711.

Zhen W, Chen X.

https://pubmed.ncbi.nlm.nih.gov/39544085/

1129. Electrostatic Assembly of Gold Nanoclustersin Reverse Emulsion Enabling Nanoassemblies with Tunab NIR-II FluorescenceImaging.

ACS Nano. 2024 Nov 19;18(46):32126-32144.

Sun Y, Qu F, Geng R, Xiao W, Bi D, Xiong B, Liu Y,Zhu J, Chen X.

https://pubs.acs.org/doi/10.1021/acsnano.4c10973

1128. Molecular probes for tracking lipid dropletmembrane dynamics.

Nat Commun. 2024 Oct 31;15(1):9413. doi: 10.1038/s41467-024-53667-7.

Kong L, Bai Q, Li C, Wang Q, Wang Y, Shao X, Wei Y,Sun J,Yu Z, Yin J, Shi B, Fang H, Chen X, Chen Q.

https://pmc.ncbi.nlm.nih.gov/articles/PMC11528070/

1127. Omics-Enhanced Nanomedicine for CancerTherapy.

Adv Mater. 2024 Oct 30:e2409102. doi: 10.1002/adma.202409102.

Qi L, Li Z, Liu J, Chen X.

https://onlinelibrary.wiley.com/doi/epdf/10.1002/adma.202409102

1126. Head-to-Head Comparison of[68Ga]Ga-NOTA-RM26 and [18F]FDG PET/CT in Patients with Gastrointesti Study.

J Nucl Med. 2024 Oct 24:jnumed.124.267810.

Wang R, Kang W, Liu Z, Zheng Y, Sui H, Li L, Wang J,Xiang J, Peng X, Chen X, Zhu Z, Zhang J.

https://jnm.snmjournals.org/content/early/2024/10/24/jnumed.124.267810.long

1125. Pulling the Rug Out from Under:Biomechanical Microenvironment Remodeling for Induction of Hepatic S

Adv Mater. 2024 Oct 15:e2406590. doi: 10.1002/adma.202406590.

Wang H, You Q, Kang B, Jing H, Shi Z, Krizkova S,Heger Z, Adam V, Chen X, Li N.

https://onlinelibrary.wiley.com/doi/10.1002/adma.202406590

1124. [68Ga]Ga-LNC1007 versus 2-[18F]FDG in theevaluation of patients with metastatic differentiated thyroid study.

Eur J Nucl Med Mol Imaging. 2024 Oct 15. doi: 10.1007/s00259-024-06930-4.

Chen Y, Zheng S, Zang J, Shao Z,Tu D, Liu Q, Chen X,Miao W, Zhang J.

https://link.springer.com/article/10.1007/s00259-024-06930-4

1123. NIR-Actuated Botanicals/NanozymesNanofibrous Membranes for Antibiotic-Free Triple-Synergistic Ther Infections.

Adv Healthc Mater. 2024 Oct 14:e2401657. doi: 10.1002/adhm.202401657.

Dong K, Lin W, Zhu T, Sun S, Zhang C, Xu C, Cao F,Chen X.

https://onlinelibrary.wiley.com/doi/10.1002/adhm.202401657

1122. Cold Exposure Therapy SensitizesNanodrug-Mediated Radioimmunotherapy of Breast Cancer.

ACS Nano. 2024 Oct 29;18(43):29689-29703.

Qiao K, Pan Y, Zhang S, Shi G, Yang J, Zhang Z, WangK, Chen X, Ning S.

https://pubs.acs.org/doi/10.1021/acsnano.4c09021

1121. Designing nanotheranostics with machinelearning.

Nat Nanotechnol. 2024 Oct 3. doi: 10.1038/s41565-024-01753-8.

Rao L, Yuan Y, Shen X, Yu G, Chen X.

https://www.nature.com/articles/s41565-024-01753-8

1120. Polymeric nanocarrier via metabolismregulation mediates immunogenic cell death with spatiotemporal immunotherapy.

Nat Commun. 2024 Oct 4;15(1):8586.

Guo Y, Li Y, Zhang M, Ma R, Wang Y, Weng X, Zhang J,Zhang Z, Chen X, Yang W.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450208/

1119. Synthetic nanomaterials for spleen-specificmRNA delivery.

Biomaterials. 2024 Sep 28;314:122859.

Nie S, Yang B, Ma R, Zha L, Qin Y, Ou L, Chen X, LiL.

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1118. Synergistic Gas Therapy and TargetedInterventional Ablation With Size-Controllable Arsenic Sulfide (As Eliminationof Localized Cancer Pain.

Small. 2024 Oct 2:e2407197.

Tang Y, Zhang J, Yuan Y, Shen K, Luo Z, Jia L, LongX, Peng C, Xie T, Chen X, Zhang P.

https://onlinelibrary.wiley.com/doi/10.1002/smll.202407197

1117. Developing an enhanced chimeric permutedintron-exon system for circular RNA therapeutics.

Theranostics. 2024 Sep 9;14(15):5869-5882.

Wang L, Dong C, Zhang W, Ma X, Rou W, Yang K, Cui T,Qi S, Yang L, Xie J, Yu G, Wang L, Chen X, Liu Z.

https://www.thno.org/v14p5869.htm

1116. Nanozymes in Biomedical Applications:Innovations Originated From Metal-Organic Frameworks.

Adv Healthc Mater. 2024 Sep 25:e2402066.

Zhao Y, Cheng J, Li Z, Wang J, Chen X.

https://onlinelibrary.wiley.com/doi/10.1002/adhm.202402066

1115. A nanobody-guided multifunctional T cellengager promotes strong anti-tumor responses via synergistic

J Nanobiotechnology. 2024 Sep 14;22(1):561.

Xie S, Shi W, Duan S, Huang X, Liu A, Hou X, Lin X,Zhong D, Sun S, Ding Z, Yang X, Chen X, Lu X.

https://pubmed.ncbi.nlm.nih.gov/39272205/

1114. Open-Source Throttling of CD8+ T Cells inBrain with Low-Intensity Focused Ultrasound-Guided Sequent aPD-L1 forGlioblastoma Immunotherapy

Adv Mater. 2024 Sep 12:e2407235

Dong L, Zhu Y, Zhang H, Gao L, Zhang Z, Xu X, Ying L,Zhang L, Li Y, Yun Z, Zhu D, Han C, Xu T, Yang H, Ju S, Chen X, Zh

https://onlinelibrary.wiley.com/doi/10.1002/adma.202407235

1113. The Landscape of Smart Biomaterial-BasedHydrogen Therapy.

Adv Sci (Weinh). 2024 Aug 21:e2401310.

Xu M, Wu G,You Q, Chen X.

https://onlinelibrary.wiley.com/doi/10.1002/advs.202401310

1112. Carrier-Free Nanodrugs: From Bench toBedside

ACS Nano. 2024 Aug 20. doi: 10.1021/acsnano.4c09027.

Fang F, Chen X.

https://pubs.acs.org/doi/10.1021/acsnano.4c09027

1111. Disulfidoptosis as a Novel Mechanism ofNeuronal Death: Insights from Creutzfeldt-Jakob Disease.

World Neurosurg. 2024 Aug 17:S1878-8750(24)01439-6. doi:10.1016/j.wneu.2024.08.070.

Wu Q, Liu SP, Liu C, Chen X, Zhou H, Zhao H.

https://linkinghub.elsevier.com/retrieve/pii/S1878-8750(24)01439-6

1110. Development of [177Lu]Lu-LNC1010 for peptidereceptor radionuclide therapy of nasopharyngeal carcin

Eur J Nucl Med Mol Imaging. 2024 Aug 15. doi: 10.1007/s00259-024-06874-9.

Chen J, Pang Y, Liao X, Zhou Y, Luo Q, Wu H, Zuo C,Zhang J, Lin Q, Chen X, Zhao L, Chen H.

https://link.springer.com/article/10.1007/s00259-024-06874-9

1109. Lung ultrasound score evaluation of theeffect of pressure-controlled ventilation volume-guaranteed on assisted radicalgastrectomy.

World J Gastrointest Surg. 2024 Jun 27;16(6):1717-1725.

Tan J, Bao CM, Chen XY.

https://www.wjgnet.com/1948-9366/full/v16/i6/1717.htm

1108. Metal-polyphenol self-assembled nanodots forNIR-II fluorescence imaging-guided chemodynamic/photo ferroptosis.

Acta Biomater. 2024 Jul 23:S1742-7061(24)00388-X.

Zhu Y, Ding C, Fang W, Li T, Yan L,Tian Y, Huang W,Wei P, Ma J, Lin X, Huang W, Lin Y, Zou J, Chen X.

https://www.sciencedirect.com/science/article/abs/pii/S174270612400388X?via%3Dihub

1107. Targeted Radionuclide Therapy inGlioblastoma.

ACS Appl Mater Interfaces. 2024 Aug 7;16(31):40391-40410.

Zhao X, Jakobsson V,Tao Y, Zhao T, Wang J, Khong PL,Chen X, Zhang J.

https://pubmed.ncbi.nlm.nih.gov/39042829/

1106. Precise Identification of GlioblastomaMicro-Infiltration at Cellular Resolution by Raman Spectroscopy

Adv Sci (Weinh). 2024 Jul 31:e2401014.

Zhu L, Li J, Pan J, Wu N, Xu Q, Zhou QQ, Wang Q, HanD, Wang Z, Xu Q, Liu X, Guo J, Wang J, Zhang Z, Wang Y, Cai H, L

https://onlinelibrary.wiley.com/doi/10.1002/advs.202401014

1105. A Dual-Targeting, Multi-FacetedBiocompatible Nanodrug Optimizes the Microenvironment to Ameliorate

Adv Mater. 2024 Jun 24:e2405761.

Mo F, Wang C, Li S, Li Z, Xiao C, Zhang Y, Hu C, WangE, Lin P,Yuan T, Zuo Z, Fu W, Chen X, Ren L, Wang L.

https://onlinelibrary.wiley.com/doi/10.1002/adma.202405761

1104. Multifaceted Carbonized Metal-OrganicFrameworks Synergize with Immune Checkpoint Inhibitors for Pr Cancer Therapy

ACS Nano. 2024 Jun 28. doi: 10.1021/acsnano.4c04022.

Zhao C,Tang X, Chen X, Jiang Z.

https://pubs.acs.org/doi/10.1021/acsnano.4c04022

1103. Engineering of a DNA/γPNA HybridNanoreporter for ctDNA Mutation Detection via γPNA Urinalysis

Adv Sci (Weinh). 2024 Jul 3:e2310225

Xiang Z, Lu J, Ming Y, Guo W, Chen X, Sun W.

https://onlinelibrary.wiley.com/doi/10.1002/advs.202310225

1102. Antitumor efficacy and potential mechanismof FAP-targeted radioligand therapy combined with immune

Signal Transduct Target Ther. 2024 Jun 3;9(1):142.

Zhao L, Pang Y, Zhou Y, Chen J, Fu H, Guo W, Xu W,Xue X, Su G, Sun L, Wu H, Zhang J, Wang Z, Lin Q, Chen X, Chen H

https://www.nature.com/articles/s41392-024-01853-w

1101. Manipulating calcium homeostasis withnanoplatforms for enhanced cancer therapy.

Exploration (Beijing). 2023 Oct 10;4(1):20230019. doi: 10.1002/EXP.20230019.

Feng Y, Wang J, Cao J, Cao F, Chen X.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10867402/

1100. Neuroprotective effects of anti-TRAIL-ICGnanoagent and its multimodal imaging evaluation in cerebral i

Mater Today Bio. 2024 May 22;26:101094. doi: 10.1016/j.mtbio.2024.101094.

Yang Q, Ye W, Luo D, Xing J, Xiao Q, Wu H, Yao Y,Wang G, Yang L, Guo D, Wang K, He Y, Ye X, Zhang J, Jin Z, Fan Z, Wen

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11157279/

1099. Diagnostic performance and clinical impactof 18F-AlF-NOTA-octreotide in a large cohort of patients with prospectivesingle-center study.

Theranostics. 2024 May 19;14(8):3213-3220.

Hou G, Cheng X, Yang Y, Zhao D, Wang G, Zhao H, ZhengR, Wang X, Chen X, Chi Y, Zhang J.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155396/

1098. "AquaF" Building Blocks forWater-Compatible SN2 18F-Fluorination of Small-Molecule Radiotracers.

J Am Chem Soc. 2024 Jun 13. doi: 10.1021/jacs.4c05854.

Mou Z, Zhu Y, Zhang L, Ma M, Li Z, Guo Y, Zheng J,Zhao Z, Zhang K, Chen X, Li Z.

https://pubs.acs.org/doi/10.1021/jacs.4c05854

1097. Engineered Antibodies as CancerRadiotheranostics.

Adv Sci (Weinh). 2024 Jun 14:e2402361. doi: 10.1002/advs.202402361.

Wei Z, Li B, Wen X, Jakobsson V, Liu P, Chen X, ZhangJ.

https://onlinelibrary.wiley.com/doi/10.1002/advs.202402361

1096. Nanomaterial-Based Strategies forAttenuating T-Cell-Mediated Immunodepression in Stroke Patients: Ad

Int J Nanomedicine. 2024 Jun 12;19:5793-5812.

Wang Y, Liu C, Ren Y, Song J, Fan K, Gao L, Ji X,Chen X, Zhao H.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11180442/

1095. Hairpin DNA-Based Nanomaterials for TumorTargeting and Synergistic Therapy

Int J Nanomedicine. 2024 Jun 12;19:5781-5792.

Shan L, Li Y, Ma Y, Yang Y, Wang J, Peng L, Wang W,Zhao F, Li W, Chen X

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11180469/

1094. Wake biofilm up to enhance suicidal uptakeof gallium for chronic lung infection treatment.

Biomaterials. 2024 May 17;310:122619. doi:10.1016/j.biomaterials.2024.122619.

He J, Lin X, Zhang D, Hu H, Chen X, Xu F, Zhou M.

https://linkinghub.elsevier.com/retrieve/pii/S0142-9612(24)00153-4

1093. olyprodrug nanomedicine forchemiexcitation-triggered self-augmented cancer chemotherapy and gas t

Biomaterials. 2024 Sep;309:122606. doi:10.1016/j.biomaterials.2024.122606.

Wang Q, Zhang C, Zhao Y, Jin Y, Zhou S, Qin J, ZhangW, Hu Y, Chen X, Yang K.

https://linkinghub.elsevier.com/retrieve/pii/S0142-9612(24)00140-6

1092. Albumin-seeking dyes with adjustableassemblies in situ enable programmable imaging windows and ta

Theranostics. 2024 Apr 15;14(7):2675-2686

Du Y, Xu J, Han T, Jiang Z, Zhang Y, Li J, Chen X,Zhu S.

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1091. Prostate-specific membrane antigen-targetedsurgery in prostate cancer: Accurate identification, real-tim

Theranostics. 2024 Apr 22;14(7):2736-2756

Jiao J, Zhang J, Wen W, Qin W, Chen X.

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1090. Immunological nanomaterials to combat cancermetastasis.

Chem Soc Rev. 2024 May 15. doi: 10.1039/d2cs00968d

Pan Y, Cheng J, Zhu Y, Zhang J, Fan W, Chen X.

https://pubs.rsc.org/en/content/articlelanding/2024/cs/d2cs00968d

1089. Diagnostic Performance of [18F]AlF-ThretidePET/CT in Patients with Newly Diagnosed Prostate Cancer Standard

J Nucl Med. 2024 May 9:jnumed.123.266940. doi:10.2967/jnumed.123.266940.

Zang J, Yang Y, Chen S, Wang C, Chen S, Hu S, Cai H,Li X, Xu N, Chen X, Zhang J, Miao W

https://jnm.snmjournals.org/content/early/2024/05/09/jnumed.123.266940.long

1088. Carboxylesterase Activatable Molecular Probefor Personalized Treatment Guidance by Analyte-Induced

Angew Chem Int Ed Engl. 2024 May 10:e202404093. doi: 10.1002/anie.202404093

Li B, Liu H, Zhao M, Zhang X, Huang P, Chen X, Lin J

https://onlinelibrary.wiley.com/doi/10.1002/anie.202404093

1087. Partial root-zone drying combined withnitrogen treatments mitigates drought responses in rice.

Front Plant Sci. 2024 Apr 15;15:1381491.

Zhao M, Gao Z, Kuang C, Chen X.

https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2024.1381491/full

1086. A Guanidinobenzol-Rich Polymer OvercomingCascade Delivery Barriers for CRISPR-Cas9 Genome Edit

Nano Lett. 2024 Apr 29. doi: 10.1021/acs.nanolett.4c00533.

Liang S, Ma N, Li X, Yun K, Meng QF, Ma K, Yue L, RaoL, Chen X, Wang Z.

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1085. Design and Characterization of a NewFormulation for the Delivery of COVID-19-mRNA Vaccine to the Na

Vaccines (Basel). 2024 Apr 12;12(4):409.

Altay Benetti A,Tan EYZ, Chang ZW, Bae KH,Thwin MT,Muthuramalingam RPK, Liao KC, Wan Y, Ng LFP, Renia L, Liu J

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1084. Double-Layered Hollow Mesoporous CuprousOxide Nanoparticles for Double Drug Sequential Therapy o

Adv Mater. 2024 Apr 26:e2313212.

Li Z, Yang J, Ren B, Fan Q, Huang L, Guo S, Zhou R,Chen S, Feng J, Yan C, Chen X, Shen Z.

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1083. Expression of concern: Gadolinium embeddediron oxide nanoclusters as T1-T2 dual-modal MRI-visible v delivery.

Nanoscale. 2024 Apr 25. doi: 10.1039/d4nr90085e.

Wang X, Zhou Z, Wang Z, Xue Y,   Zeng Y, Gao J, Zhu L, Zhang X, Liu G, Chen X.

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1082. A mesoporous superparamagnetic iron oxidenanoparticle as a generic drug delivery system for tumor f

J Nanobiotechnology. 2024 Apr 24;22(1):204.

Yang J, Xiong W, Huang L, Li Z, Fan Q, Hu F, Duan X,Fan J, Li B, Feng J, Xu Y, Chen X, Shen Z.

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1081. Programming peptide-oligonucleotidenano-assembly for engineering of neoantigen vaccine with potent

Theranostics. 2024 Mar 17;14(6):2290-2303

Xiang Z, Lu J, Rao S, Fu C, Yao Y, Yi Y, Ming Y, SunW, Guo W, Chen X.

https://www.thno.org/v14p2290.htm

1080. Theranostics - a sure cure for cancer after100 years?

Theranostics. 2024 Mar 31;14(6):2464-2488. doi: 10.7150/thno.96675

Song Y, Zou J, Castellanos EA, Matsuura N, Ronald JA,Shuhendler A, Weber WA, Gilad AA, Müller C, Witney TH, Chen

https://www.thno.org/v14p2464.htm

1079. Spatiotemporal Concurrent PARP InhibitorSensitization based on Radiation-Responsive Nanovesicles f

Adv Healthc Mater. 2024 Apr 10:e2400908.

Kang F, Niu M, Zhou Z, Zhang M, Xiong H, Zeng F, WangJ, Chen X.

https://onlinelibrary.wiley.com/doi/10.1002/adhm.202400908

1078. A DNA origami device spatially controls CD95signalling to induce immune tolerance in rheumatoid arth

Nat. Mater. (2024). DOI:10.1038/s41563-024-01865-5

Ling Li, Jue Yin, Wen Ma, Longguang Tang, JianhuaZou, Linzi Yang,Ting Du, Yi Zhao, Lianhui Wang, Zhen Yang, Chunh

https://doi.org/10.1038/s41563-024-01865-5

1077. Carrier-Free Self-AssemblyNano-Sonosensitizers for Sonodynamic-Amplified Cuproptosis-Ferroptosis i

Adv Sci (Weinh). 2024 Apr 6:e2402516. doi: 10.1002/advs.202402516

Zhu Y, Niu X, Ding C, Lin Y, Fang W, Yan L, Cheng J,Zou J,Tian Y, Huang W, Huang W, Pan Y, Wu T, Chen X, Kang D

https://onlinelibrary.wiley.com/doi/10.1002/advs.202402516

1076. Clinical translation of a novel FAPI dimer[68Ga]Ga-LNC1013.

Eur J Nucl Med Mol Imaging. 2024 Apr 2. doi: 10.1007/s00259-024-06703-z

Tan Y, Li J, Zhao T, Zhou M, Liu K, Xiang S, Tang Y,Jakobsson V, Xu P, Chen X, Zhang J.

https://link.springer.com/article/10.1007/s00259-024-06703-z

1075. Narrow Bandgap Schottky HeterojunctionSonosensitizer with High Electron-Hole Separation Boosted S Cancer

Adv Mater. 2024 Mar 28:e2401252

Li G, Wu S, Liu J, Wang K, Chen X, Liu H.

https://onlinelibrary.wiley.com/doi/10.1002/adma.202401252

1074. Neutrophil Targeting Platform ReducesNeutrophil Extracellular Traps for Improved Traumatic Brain Injury

Adv Sci (Weinh). 2024 Mar 23:e2308719. doi: 10.1002/advs.202308719

Mu Q,Yao K, Syeda MZ, Wan J, Cheng Q, You Z, Sun R,Zhang Y, Zhang H, Lu Y, Luo Z, Li Y, Liu F, Liu H, Zou X, Zhu Y, Pe

https://pubmed.ncbi.nlm.nih.gov/38520727/

1073. Neutrophil Membrane-Camouflaged PolyprodrugNanomedicine for Inflammation Suppression in Ischem

Adv Mater. 2024 Mar 22:e2311803. doi: 10.1002/adma.202311803

Zhao Y, Li Q, Niu J, Guo E, Zhao C, Zhang J, Liu X,Wang L, Rao L, Chen X, Yang K.

https://onlinelibrary.wiley.com/doi/10.1002/adma.202311803

1072. Targeting Strategies for Site-Specific mRNADelivery

Bioconjug Chem. 2024 Mar 16. doi: 10.1021/acs.bioconjchem.4c00038

Di J, Huang P, Chen X

https://pubs.acs.org/doi/10.1021/acs.bioconjchem.4c00038

1071. Coassembly Nanomedicine Mediated byIntermolecular Interactions Between Methotrexate and Baricitin Treatment.

ACS Nano. 2024 Mar 4. doi: 10.1021/acsnano.3c12692

Xiong H, Zhang H, Qin Y, Ye J, Zeng F, Xie P, Shi C,Luo C, Xu W, Yu C, Zhou Z, Chen X

https://pubs.acs.org/doi/10.1021/acsnano.3c12692

1070. Nanomedicines for an Enhanced ImmunogenicCell Death-Based In Situ Cancer Vaccination Response

Acc Chem Res. 2024 Feb 28. doi: 10.1021/acs.accounts.3c00771

Zhao C, Wang C, Shan W, Wang Z, Chen X, Deng H.

https://pubs.acs.org/doi/10.1021/acs.accounts.3c00771

1069. Self-Adjuvanting Polyguanidine Nanovaccinesfor Cancer Immunotherapy

ACS Nano. 2024 Feb 26. doi: 10.1021/acsnano.3c11637

Zhang X, Wang K, Zhao Z, Shan X, Wang Y, Feng Z, LiB, Luo C, Chen X, Sun J

https://pubmed.ncbi.nlm.nih.gov/38407021/

1068. Advancing nanotechnology forneoantigen-based cancer theranostics

Chem Soc Rev. 2024 Feb 21. doi: 10.1039/d3cs00162h.

Zou J, Zhang Y, Pan Y, Mao Z, Chen X

https://pubmed.ncbi.nlm.nih.gov/38379286/

1067. Synthesis, preclinical, and initial clinicalevaluation of integrin αVβ3 and gastrin-releasing peptide recep[68Ga]Ga-RGD-RM26-03.

Eur J Nucl Med Mol Imaging. 2024 Feb 20. doi: 10.1007/s00259-024-06634-9.

Wen X, Wang R, Xu P, Shi M, Shang Q, Zeng X, Zeng X,Liu J, Wang X, Zhu Z, Guo Z, Chen X, Zhang J.

https://pubmed.ncbi.nlm.nih.gov/38376806/

1066. A non-metal single atom nanozyme for cuttingoff the energy and reducing the power of tumors

Angew Chem Int Ed Engl. 2024 Feb 15:e202319982.

Cheng J, Li L, Jin D, Zhang Y, Yu W, Yu J, Zou J, DaiY, Zhu Y, Liu M, Zhang M, Sun Y, Liu Y, Chen X

https://pubmed.ncbi.nlm.nih.gov/38361437/

1065. Apoptotic Vesicular Metabolism Contributesto Organelle Assembly and Safeguards Liver Homeostasis a

Gastroenterology. 2024 Feb 9:S0016-5085(24)00136-7.

Sui B, Wang R, Chen C, Kou X, Wu D, Fu Y, Lei F, WangY, Liu Y, Chen X, Xu H, Liu Y, Kang J, Liu H, Kin Kwok RT,Tang BZ Ma L, Shi S,Jin Y.

https://pubmed.ncbi.nlm.nih.gov/38342194/

1064. AcousticRobots: Smart acoustically poweredmicro-/nanoswimmers for precise biomedical applications

Adv Drug Deliv Rev. 2024 Feb 6;207:115201

Wu G, Xian W, You Q, Zhang J, Chen X

https://pubmed.ncbi.nlm.nih.gov/38331256/

1063. Redox-responsive polymer micellesco-encapsulating immune checkpoint inhibitors and chemotherapeu

Nat Commun. 2024 Feb 6;15(1):1118

Zhang Z, Xu X, Du J, Chen X, Xue Y, Zhang J, Yang X,Chen X, Xie J, Ju S.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10847518/

1062. pH/GSH dual responsive nanosystem for nitricoxide generation enhanced type I photodynamic therapy

Bioact Mater. 2024 Jan 10;34:414-421. doi:10.1016/j.bioactmat.2023.12.023.

Zou J, Li Z, Zhu Y,Tao Y, You Q, Cao F, Wu Q, Wu M,Cheng J, Zhu J, Chen X

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10825229/

1061. Development and Applications of D-Amino AcidDerivatives-based Metabolic Labeling of Bacterial Peptid

Angew Chem Int Ed Engl. 2024 Jan 29:e202319400

Zheng Y, Zhu X, Jiang M, Cao F,You Q, Chen X

https://onlinelibrary.wiley.com/doi/10.1002/anie.202319400

1060. Microalgae-Based Hydrogel for InflammatoryBowel Disease and Its Associated Anxiety and Depression

Adv Mater. 2024 Jan 26:e2312275. doi: 10.1002/adma.202312275

Zhong D, Jin K, Wang R, Chen B, Zhang J, Ren C, ChenX, Lu J, Zhou M

https://onlinelibrary.wiley.com/doi/10.1002/adma.202312275

1059. Lipodystrophy in methylmalonic acidemiaassociated with elevated FGF21 and abnormal methylmalonyl

JCI Insight. 2024 Feb 22;9(4):e174097

Manoli I, Sysol JR, Head PE, Epping MW, Gavrilova O,Crocker MK, Sloan JL, Koutsoukos SA, Wang C, KtenaYP, Mend Vernon HJ, FletcherLA, Reynolds JC,Tsokos MG, Stratakis CA,Voss SD, Chen KY, Brown RJ, Hamosh A,Berry GT, Ch

https://pubmed.ncbi.nlm.nih.gov/38271099/

1058. Mitochondria-specific near-infraredphotoactivation of peroxynitrite upconversion luminescent nanogen therapy

Acta Pharm Sin B. 2024 Jan;14(1):378-391

Yu H,Tiemuer A, Yao X, Zuo M, Wang HY, Liu Y, Chen X

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10792980/

1057. A comparison of [18F]AlF- and 68Ga-labeleddual targeting heterodimer FAPI-RGD in malignant tumor: p PET/CT imaging

Eur J Nucl Med Mol Imaging. 2024 Jan 22. doi: 10.1007/s00259-023-06587-5

Liu N, Wan Q, Wu X, Zhao T, Jakobsson V,Yuan H, ChenX, Zhang J, Zhang W

https://link.springer.com/article/10.1007/s00259-023-06587-5

1056. In Situ Reprogramming of Immune Cells UsingSynthetic Nanomaterials

Advanced materials (Deerfield Beach, Fla.). 2024, e2310168.

Nie, S., Qin,Y., Ou, L., Chen, X., & Li, L.

https://doi.org/10.1002/adma.202310168

1055. First-in-human validation of enzymolysisclearance strategy for decreasing renal radioactivity using mod

European journal of nuclear medicine and molecularimaging. 2024,10.1007/s00259-023-06584-8.

Zhang, M., Kang, F., Xing,T., Wang, J., Ma,T., Li,G., Quan, Z., Yang, W., Chen, X., & Wang, J.

https://doi.org/10.1007/s00259-023-06584-8

1054. Synergistic Glutathione Depletion and STINGActivation to Potentiate Dendritic Cell Maturation and Canc

Angewandte Chemie (International ed. in English). 2024, e202318530.

Liu, J., Zhang, Y., Yang, B., Jia,Y., Liu, R.T.,Ding, L., Shen, Z., & Chen, X.

https://doi.org/10.1002/anie.202318530

1053. Long-term Nephrotoxicity after PRRT: Myth orReality.

Theranostics. 2024, 14(2), 451–459

Baum, R. P., Fan, X., Jakobsson,V., Yu, F.,Schuchardt, C., Chen, X., & Zhang, J.

https://doi.org/10.7150/thno.92487

1052. Lower-grade gliomas surgery guided byGRPR-targeting PET/NIR dual-modality image probe: a prospect

Theranostics. 2024, 14(2), 819–829

Chen, L., Zhang, J., Chi, C., Che, W., Dong, G.,Wang, J., Du, Y., Wang, R., Zhu, Z.,Tian, J., Ji, N., Chen, X., & Li, D.

https://doi.org/10.7150/thno.91554

1051. LCP1 knockdown in monocyte-derivedmacrophages: mitigating ischemic brain injury and shaping imm

Theranostics. 2024, 14(1), 159–175

Wang, Y., Yin, Q., Yang, D., Jin, H.,Yao,Y., Song,J., Liu, C., Nie, Y., Yin, H., Wang, W., Xu, B., Xue, L., Ji, X., Chen, X.,& Zha

https://doi.org/10.7150/thno.88678

 

1050. Redox-Active Ferrocene Quencher-BasedSupramolecular Nanomedicine for NIR-II Fluorescence-Monitored ChemodynamicTherapy

Angewandte Chemie (International ed. in English), 2023, e202318155

Yu, M., Ye, Z., Liu, S., Zhu, Y., Niu, X., Wang, J.,Ao, R., Huang, H., Cai, H., Liu, Y., Chen, X., & Lin, L.

https://doi.org/10.1002/anie.202318155

1049.A Side-Effect-Free Interventional Therapy forPrecisely Eliminating Unresectable Cancer Pain.

ACS nano, 2023, 17(23), 23535–23544.

Zhang, P., Yao, S.,Tang, Y., Wan, S., Chen, X., &Ma, L.

https://doi.org/10.1021/acsnano.3c06511

1048. Rapid visualization of PD-L1 expressionlevel in glioblastoma immune microenvironment via machine learningcascade-based Raman histopathology.

Journal of advanced research, 2023, S2090-1232(23)00377-6.

Zhou, Q. Q., Guo, J., Wang, Z., Li, J., Chen, M., Xu,Q., Zhu, L., Xu, Q., Wang, Q., Pan, H., Pan, J., Zhu, Y., Song, M., Liu, X.,Wang, J., Zhang, Z., Zhang, L., Wang, Y., Cai, H., Chen, X., Lu, G.

https://doi.org/10.1016/j.jare.2023.12.002

1047. Single-arm trials for domestic oncology drugapprovals in China

Cancer biology & medicine, 2023, 20(11), 799–805.

Zhang, H., Liu, S., Ge, C., Liu, X., Liu, Y., Yin,C., Li, Y., An, J., Yan, Z., & Chen, X.

https://doi.org/10.20892/j.issn.2095-3941.2023.0360

1046. Fabrication of An ImmunostimulatorySupramolecular Nanomedicine for Potent Cancer Chemoimmunotherapy

JACS Au, 2023, 3(11), 3181–3193.

Yu, X., Qi, S., Cao, F., Yang, K., Li, H., Peng, K.,Liu, Z., Bai, B., Buljan, M., Chen, X., & Yu, G.

https://doi.org/10.1021/jacsau.3c00515

1045. Extended peptide receptor radionuclidetherapy: evaluating nephrotoxicity and therapeutic effectiveness inneuroendocrine tumor patients receiving more than four treatment cycles

European journal of nuclear medicine and molecularimaging, 2023,10.1007/s00259-023-06544-2.

Baum, R. P., Fan, X., Jakobsson,V., Schuchardt, C.,Chen, X., Yu, F., & Zhang, J.

https://doi.org/10.1007/s00259-023-06544-2

1044. Cell Death Pathway Regulation by FunctionalNanomedicines for Robust Antitumor Immunity

Advanced science (Weinheim, Baden-Wurttemberg,Germany), 2023， e2306580.

Li, Y., Guo, Y., Zhang, K., Zhu, R., Chen, X., Zhang,Z., & Yang, W.

https://doi.org/10.1002/advs.202306580

1043. Ultrathin Clay Nanoparticles-Mediated MutualReinforcement of Ferroptosis and Cancer Immunotherapy.

Advanced materials (Deerfield Beach, Fla.), 2023, e2309562.

Liu, J., Zhan, J., Zhang, Y., Huang, L., Yang, J.,Feng, J., Ding, L., Shen, Z., & Chen, X.

https://doi.org/10.1002/adma.202309562

1042. Peroxynitrite-Scavenging Organosilica Nanomedicinesfor Light-Controllable NO Release and Precision On-Demand Glaucoma Therapy.

ACS nano, 2023, 10.1021/acsnano.3c02685.

Song, M., Li, L., Liu, J., Gao, Y., Li, M., Zhou, L.,Qin, B., Xiang, A., Sun, X., Fan, W., Lei, Y., & Chen, X.

https://doi.org/10.1021/acsnano.3c02685

1041. Cellular Trafficking ofNanotechnology-Mediated mRNA Delivery

Advanced materials (Deerfield Beach, Fla.), 2023, e2307822.

Huang, P., Deng, H., Wang, C., Zhou, Y., & Chen,X.

https://doi.org/10.1002/adma.202307822

1040. Stimuli-Responsive Nanoadjuvant Rejuvenates RobustImmune Responses to Sensitize Cancer Immunotherapy.

ACS nano, 2023, 10.1021/acsnano.3c06233.

Huang, R., Zhou, P., Chen, B., Zhu, Y., Chen, X.,& Min, Y.

https://doi.org/10.1021/acsnano.3c06233

1039. Fibroblast Activation Protein-TargetedPET/CT with 18F-Fibroblast Activation Protein Inhibitor-74 for Evaluation ofGastrointestinal Cancer: Comparison with 18F-FDG PET/CT.

Journal of nuclear medicine : official publication,Society of Nuclear Medicine, 2023, jnumed.123.266329.

Xu, W., Cai, J., Peng,T., Meng,T., Pang, Y., Sun, L.,Wu, H., Zhang, J., Chen, X., & Chen, H.

https://doi.org/10.2967/jnumed.123.266329

1038. Biomimetic nanovaccine-mediated multivalentIL-15 self-transpresentation (MIST) for potent and safe cancer immunotherapy.

Nature communications, 2023, 14(1), 6748

Wang, K., Zhang, X., Ye, H., Wang, X., Fan, Z., Lu,Q., Li, S., Zhao, J., Zheng, S., He, Z., Ni, Q., Chen, X., & Sun, J.

https://doi.org/10.1038/s41467-023-42155-z

1037. A phase 1 trial to determine the maximumtolerated dose and patient-specific dosimetry of [177Lu]Lu-LNC1003 in patientswith metastatic castration-resistant prostate cancer.

European journal of nuclear medicine and molecularimaging, 2023，10.1007/s00259-023-06470-3.

Zang, J., Wang, G., Zhao,T., Liu, H., Lin, X., Yang, Y.,Shao, Z., Wang, C., Chen, H., Chen, Y., Zhu, Z., Miao, W., Chen, X., &Zhang, J.

https://doi.org/10.1007/s00259-023-06470-3

1036. Oxygen-Independent Synchronized RosGeneration and Hypoxia Prodrug Activation with Z-Scheme HeterostructureSonosensitizer.

Advanced materials (Deerfield Beach, Fla.), 2023，e2307929

Chen, Y., Zou,T., Xin, G., Liu, X., Yang, Y., Wei,L., Zhang, B., Yu, P., Ren ,Y., Feng, Y., Chen, R., Cao, F., Chen, X., &Cheng, Y.

https://doi.org/10.1002/adma.202307929

1035.An in vitro-transcribed circular RNA targetsthe mitochondrial inner membrane cardiolipin to ablate EIF4G2+/PTBP1+ pan[1]adenocarcinoma.

Nature cancer, 2023， 10.1038/s43018-023-00650-8.

Feng, Z., Zhang, X., Zhou, J., Li, Q., Chu, L., Di,G., Xu, Z., Chen, Q., Wang, M., Jiang, X., Xia, H., & Chen, X.

https://doi.org/10.1038/s43018-023-00650-8

1034. Comment on: "Development of aCLDN18.2-targeting immuno-PET probe for non-invasive imaging ingastrointestinal tumors"

Journal of pharmaceutical analysis, 2023， 13(9), 958–959.

Li, C., Chen, X., & Zhang, J.

https://doi.org/10.1016/j.jpha.2023.07.010

1033.Fibroblast Activation Protein-Targeted RadioligandTherapy with 177Lu-EB-FAPI for Metastatic Radioiodine Refractory ThyroidCancer: First-in-Human, Dose-Escalation Study.

Clinical cancer research : an official journal of theAmerican Association for Cancer Research, 2023, 10.1158/1078-0432.CCR-23-1983.

Fu, H., Huang, J., Zhao,T., Wang, H., Chen, Y., Xu,W., Pang, Y., Guo, W., Sun, L., Wu, H., Xu, P., Su, B., Zhang, J., Chen, X.,& Chen, H.

https://doi.org/10.1158/1078-0432.CCR-23-1983

1032. Engineering Clinically Relevant Probioticswith Switchable "nano-promoter" and "nano-effector" forPrecision Tumor Therapy.

Advanced materials (Deerfield Beach, Fla.), 2023, e2304257

Cao, F., Jin, L., Zhang, C., Gao, Y., Qian, Z., Wen,H., Yang, S., Ye, Z., Hong, L., Yang, H.,Tong, Z., Cheng, L., Ding, Y., Wang,W., Yu, G., Mao, Z., & Chen, X.

https://doi.org/10.1002/adma.202304257

1031. Near-infrared photodynamic and photothermalco-therapy based on organic small molecular dyes.

Journal of nanobiotechnology, 2023, 21(1), 348.

Guo, S., Gu, D., Yang,Y.,Tian, J., & Chen, X.

https://doi.org/10.1186/s12951-023-02111-x

1030.[68Ga]Ga-LNC1007 PET/CT in the evaluation ofrenal cell carcinoma: comparison with 2-[18F]FDG/[68Ga]Ga-PSMA PET/CT.

European journal of nuclear medicine and molecularimaging, 2023,

10.1007/s00259-023-06436-5. Advance onlinepublication.

Lin, R., Wang, C., Chen, S., Lin,T., Cai, H., Chen,S., Yang, Y., Zhang, J., Xu, F., Zhang, J., Chen, X., Zang, J., & Miao, W.

https://doi.org/10.1007/s00259-023-06436-5

 

1029. Tumor Microenvironment-ResponsiveNanoparticles Amplifying STING Signaling Pathway for Cancer Immunotherapy.

Advanced materials (Deerfield Beach, Fla.), 2023, e2304845. Advance online publication.

Liu, D., Liang, S., Ma, K., Meng, Q. F., Li, X., Wei,J., Zhou, M., Yun, K., Pan, Y., Rao, L., Chen, X., & Wang, Z.

https://doi.org/10.1002/adma.202304845

1028. An and Logic Gate for Magnetic ResonanceImaging-Guided Ferroptosis Therapy of Tumors.

Advanced materials (Deerfield Beach, Fla.),2023,e2305932. Advance online publication.

Fan, Q., Xiong, W., Zhou, H., Yang, J., Feng, J., Li,Z., Wu, L., Hu, F., Duan, X., Li, B., Fan, J., Xu, Y., Chen, X., & Shen, Z.

https://doi.org/10.1002/adma.202305932

1027. The Landscape of Biomimetic Nanovesicles inBrain Diseases.

Advanced materials (Deerfield Beach, Fla.), 2023, e2306583. Advance online publication.

You, Q., Liang, F., Wu, G., Cao, F., Liu, J., He, Z.,Wang, C., Zhu, L., Chen, X., &   Yang,Y.

https://doi.org/10.1002/adma.202306583

1026. Theranostics on the immunoactivity of Tcells.

Clinical and translational medicine, 2023, 13(9), e1421.

Shi, C., Zhang, X., Liu, X., Chen, X., & Zhou, Z.

https://doi.org/10.1002/ctm2.1421

1025. A Head-to-Head Comparison of 68Ga-LNC1007and 2-18F-FDG/68Ga-FAPI-02 PET/CT in Patients With Various Cancers

Clinical nuclear medicine, 48(10), 861–868.

Zang, J., Lin, R., Wen, X., Wang, C., Zhao,T.,Jakobsson,V., Yang, Y., Wu, X., Guo, Z., Chen, X., Zhang, J., & Miao, W.

https://doi.org/10.1097/RLU.0000000000004820

1024. Evaluation of FAPI PET imaging in gastriccancer: a systematic review and meta-analysis

Theranostics, 13(13), 4694–4710

Ruan, D., Zhao, L., Cai, J., Xu, W., Sun, L., Li, J.,Zhang, J., Chen, X., & Chen, H.

https://doi.org/10.7150/thno.88335

1023. Exploiting Albumin as a Versatile Carrierfor Cancer Theranostics

Accounts of chemical research, 2023, 10.1021/acs.accounts.3c00309.

Tao, Y., Jakobsson,V., Chen, X., & Zhang, J.

https://doi.org/10.1021/acs.accounts.3c00309

1022. Inhaled drug delivery: Past, present, andfuture

Nano Today 52 (2023) 101942

Ludan Yue, Xue yang Zhang, Chenchen Zhao, RongchangChen, Xiao yuan Chen, Lang Rao

https://doi.org/10.1016/j.nantod.2023.101942

1021. Anti-phagocytosis-blockingrepolarization-resistant membrane-fusogenic liposome (ARMFUL) for adoptive cellimmunotherapy.

Science advances, 2023, 9(32), eadh2413

Zheng, C., Zhong, Q., Yi, K., Kong, H., Cao, F.,Zhuo, C., Xu, Y., Shi, R., Ju, E., Song, W.,Tao, Y., Chen, X., & Li, M.

https://doi.org/10.1126/sciadv.adh2413

1020. Intestinal Villi-Inspired MathematicallyBase-Layer Engineered Microneedles (IMBEMs) for Effective Molecular Exchangeduring Biomarker Enrichment and Drug Deposition in Diversified Mucosa

ACS nano, 2023, 17(16), 15696–15712

Gong, Y.,Tong, S., Li, X., Chen, X., Liu, Y., Li, N.,Xu, J., Xu, R., Guo, Y., Xiao, F., Chen, X., & Chen, W.

https://doi.org/10.1021/acsnano.3c02944

1019. J-Aggregation Strategy Toward PotentiatedNIR-II Fluorescence Bioimaging of Molecular Fluorophores.

Advanced materials (Deerfield Beach, Fla.), 2023, e2304848.

Hu, X., Zhu, C., Sun, F., Chen, Z., Zou, J., Chen,X., & Yang, Z.

https://doi.org/10.1002/adma.202304848

1018. Preclinical assessment of IRDye800CW-labeledgastrin-releasing peptide receptor-targeting peptide for near infrared-IIimaging of brain malignancies

Bioengineering & translational medicine, 2023, 8(4), e10532.

Zhang, Y., Wang, L., Zhang, C., Zhang, J., Yuan, L.,Jin, S., Zhou, W., Guan, X., Kang, P., Zhang, C.,Tian, J., Chen, X., Li, D.,& Jia, W.

https://doi.org/10.1002/btm2.10532

1017. Preface in special theme: Functionalinorganic nanomaterials for cutting-edge theranostic applications

Advanced drug delivery reviews, 2023, 199, 114991.

Xing, B., Chen, X. S.

https://doi.org/10.1016/j.addr.2023.114991

1016. Inhalation delivery of dexamethasone withiSEND nanoparticles attenuates the COVID-19 cytokine storm in mice and nonhumanprimates.

Sci Adv. 2023 Jun 16;9(24):eadg3277.

Meng QF,Tai W,Tian M, Zhuang X, Pan Y, Lai J, Xu Y,Xu Z, Li M, Zhao G, Yu GT, Yu G, Chen R, Jin N, Li X, Cheng G, Chen X, Rao L.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266725/

1015. Progress on Physical Field-RegulatedMicro/Nanomotors for Cardiovascular and Cerebrovascular Disease Treatment

Small Methods. 2023 Jun 30:e2300426.

You Q, Shao X, Wang J, Chen X. Progress on PhysicalField-Regulated Micro/ Nanomotors for Cardiovascular and CerebrovascularDisease Treatment

https://onlinelibrary.wiley.com/doi/10.1002/smtd.202300426

1014. Injectable liposomal docosahexaenoic acidalleviates atherosclerosis progression and enhances plaque stability

J Control Release. 2023 Jul 7;360:344-364.

Chong SY, Wang X, van Bloois L, Huang C, Syeda NS,Zhang S,Ting HJ, Nair V, Lin Y, Lou CKL, Benetti AA, Yu X, Lim NJY,Tan MS, LimHY, Lim SY,Thiam CH, Looi WD, Zharkova O, Chew NWS, Ng CH, Bonney GK, MuthiahM, Chen X, Pastorin G, Richards AM, Angeli V, Storm G, Wang JW.

https://www.sciencedirect.com/science/article/abs/pii/S0168365923004182?via%3Dihub

1013. Surface Engineering of Nanoparticles towardCancer Theranostics.

Accounts of chemical research, 2023, 10.1021/acs.accounts.3c00122. Advance onlinepublication.

Huang, P., Wang, C., Deng, H., Zhou, Y., & Chen,X.

https://doi.org/10.1021/acs.accounts.3c00122

1012. Hybrid Biomimetic Membrane CoatedParticles-Mediated Bacterial Ferroptosis for Acute MRSA Pneumonia.

ACS nano, 10.1021/acsnano.3c02365. Advance online publication.

Hu, H., Hua, S. Y., Lin, X., Lu, F., Zhang, W., Zhou,L., Cui, J., Wang, R., Xia, J., Xu, F., Chen, X., & Zhou, M. (2023).

https://doi.org/10.1021/acsnano.3c02365

1011. Dual targeting PET tracer [68Ga]Ga-FAPI-RGDin patients with lung neoplasms: a pilot exploratory study.

Theranostics, 2023, 13(9), 2979–2992.

Wang, R., Jakobsson,V., Wang, J., Zhao,T., Peng, X.,Li, B., Xue, J., Liang, N., Zhu, Z., Chen, X., & Zhang, J.

https://doi.org/10.7150/thno.86007

1010. Rapid Tumor Washout of 177Lu-PSMARadioligand in Renal Cell Carcinoma.

Clinical nuclear medicine, 2023, 10.1097/RLU.0000000000004725. Advance onlinepublication.

Zhang, J., Schuchardt, C., Chen, X., & Baum, R.P.

https://doi.org/10.1097/RLU.0000000000004725

1009. Gas therapy potentiates aggregation-inducedemission luminogen-based photoimmunotherapy of poorly immunogenic tumorsthrough cGAS-STING pathway activation

Nature communications, 2023, 14(1), 2950.

Wang, K., Li, Y., Wang, X., Zhang, Z., Cao, L., Fan,X., Wan, B., Liu, F., Zhang, X., He, Z., Zhou, Y., Wang, D., Sun, J., &Chen, X.

https://www.nature.com/articles/s41467-023-38601-7

1008. Tuning the Organ Tropism of Polymersome forSpleen-Selective Nanovaccine Delivery to Boost Cancer Immunotherapy.

Advanced materials (Deerfield Beach, Fla.), e2301686.

Gu, W., An, J., Li, Y., Yang, Y., Wang, S., Shan, H.,Li, S., Li, H., Liu, G., Li, K., Yin, Y., Mu, J., & Chen, X.

https://doi.org/10.1002/adma.202301686

1007. Orchestrated strategies for developingfluorophores for NIR-II imaging.

Advanced healthcare materials, e2300537.

Feng, X., Wei, L., Liu, Y., Chen, X., & Tian, R.

https://doi.org/10.1002/adhm.202300537

 

1006. Tumor-microenvironment-responsivepoly-prodrug encapsulated semiconducting polymer nanosystem for phototherapy[1]boostedchemotherapy.

Materials horizons, 2023, 10.1039/d3mh00242j.

Zhu, J., Zhang, Y., Li, Z., Bao, X., Zhou, Y., Ma,B., Xie, Y., Yan, P., Wu, Z., Zhang, Q., Zou, J., & Chen, X.

https://doi.org/10.1039/d3mh00242j

1005. Clinical Evaluation of 68Ga-FAPI-RGD forImaging of Fibroblast Activation Protein and Integrin αvβ3 in Various CancerTypes.

Journal of nuclear medicine : official publication,Society of Nuclear Medicine, 2023, jnumed.122.265383. Advance online publication.

Zhao, L., Wen, X., Xu, W., Pang, Y., Sun, L., Wu, X.,Xu, P., Zhang, J., Guo, Z., Lin, Q., Chen, X., & Chen, H.

https://doi.org/10.2967/jnumed.122.265383

1004. Gas-Mediated Tumor Energy Remodeling forSensitizing Mild Photothermal Therapy.

Angewandte Chemie (International ed. in English), 2023, e202304312. Advance online publication.

Cheng, J., Zhu, Y., Dai, Y., Li, L., Zhang, M., Jin,D., Liu, M., Yu, J., Yu, W., Su, D., Zou, J., Chen, X., & Liu, Y.

https://doi.org/10.1002/anie.202304312

1003. Development of [177Lu]Lu-LNC1003 forradioligand therapy of prostate cancer with a moderate level of PSMAexpression.

European journal of nuclear medicine and molecularimaging, 2023,10.1007/s00259-023-06229-w. Advance online publication.

Wen, X., Xu, P., Zeng, X., Liu, J., Du, C., Zeng, X.,Cheng, X., Wang, X., Liang, Y., Zhao,T., Yang, H., Li, H., Meng, L., Fang, J.,Liu, H., Zhou, Z., Zhang, J., Zhang, X., Guo, Z., & Chen, X.

https://doi.org/10.1007/s00259-023-06229-w

1002. Ligustrazine Nanoparticle Hitchhiking onNeutrophils for Enhanced Therapy of Cerebral Ischemia-Reperfusion Injury.

Advanced science (Weinheim, Baden-Wurttemberg,Germany), 2023, e2301348.

Mu, Q., Yao, K., Syeda, M. Z., Zhang, M., Cheng, Q.,Zhang, Y., Sun, R., Lu, Y., Zhang, H., Luo, Z., Huang, H., Liu, X., Luo, C.,Zhu, X., Wu, S., Cui, L., Huang, C., Chen, X., & Tang, L.

https://doi.org/10.1002/advs.202301348

1001. Evaluation of Safety, Biodistribution, andDosimetry of a Long-Acting Radiolabeled Somatostatin Analog 177Lu-DOTA-EB-TATEWith and Without Amino Acid Infusion

Clinical nuclear medicine, 2023, 10.1097/RLU.0000000000004642. Advance onlinepublication.

Jiang, Y., Liu, Q., Wang, G., Zhang, J., Zhu, Z.,& Chen, X.

https://doi.org/10.1097/RLU.0000000000004642

1000. Activatable NIR-II Photothermal LipidNanoparticles for Improved Messenger RNA Delivery

Angewandte Chemie (International ed. in English), 2023, e202302676. Advance online publication.

Li, B., Zhao, M., Lai, W., Zhang, X., Yang, B., Chen,X., & Ni, Q.

https://doi.org/10.1002/anie.202302676

999. Engineering Single-Atom Nanozymes forCatalytic Biomedical Applications.

Small 2023, (Weinheim an der Bergstrasse, Germany), e2300750.Advance online publication.

Zhu, Y., Liao, Y., Zou, J., Cheng, J., Pan, Y., Lin,L., & Chen, X.

https://doi.org/10.1002/smll.202300750

998. Milk-derived extracellular vesicles protectintestinal barrier integrity in the gut-liver axis.

Science advances, 2023， 9(15), eade5041.

Tong, L., Zhang, S., Liu, Q., Huang, C., Hao, H.,Tan,M. S., Yu, X., Lou, C. K. L., Huang, R., Zhang, Z., Liu,T., Gong, P., Ng, C.H., Muthiah, M., Pastorin, G., Wacker, M. G., Chen, X., Storm, G., Lee, C. N.,Zhang, L.,H. Yi, Wang, J. W.

https://doi.org/10.1126/sciadv.ade5041

997. Water-Soluble Au25 Clusters withSingle-Crystal Structure for Mitochondria-Targeting Radioimmunotherapy.

ACS nano, 10.1021/acsnano.3c01068. Advance online publication.

Hua, Y., Shao, Z. H., Zhai, A., Zhang, L. J., Wang,Z. Y., Zhao, G., Xie, F., Liu, J. Q., Zhao, X., Chen, X., & Zang, S. Q.

https://doi.org/10.1021/acsnano.3c01068

996. Materials engineering strategies for cancervaccine adjuvant development.

Chemical Society reviews, 10.1039/d2cs00647b. Advance online publication.

Zhang, X., Yang, B., Ni, Q., & Chen, X.

https://doi.org/10.1039/d2cs00647b

995. Integrative network-based analysis onmultiple Gene Expression Omnibus datasets identifies novel immune molecularmarkers

implicated in non-alcoholic steatohepatitis.

Frontiers in endocrinology, 2023， 14, 1115890.

Zhang, J. J., Shen, Y., Chen, X. Y., Jiang, M. L., Yuan,F. H., Xie, S. L., Zhang, J., & Xu, F.

https://doi.org/10.3389/fendo.2023.1115890

994.Aspartate beta-hydroxylase domain containing 1as a prognostic marker associated with immune infiltration in skin cutaneous

melanoma

BMC cancer, 2023，23(1), 292.

Sun, S., Deng, M., Wen, J., Chen, X., Xu, J., Liu, Y.,Wan, H., Wang, J., Yan, L., He, Y., & Xu, Y.

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993. Artificial-enzymes-armed Bifidobacteriumlongum probiotics for alleviating intestinal inflammation and microbiotadysbiosis.

Nature nanotechnology, 2023, 10.1038/s41565-023-01346-x. Advance onlinepublication.

Cao, F., Jin, L., Gao, Y., Ding, Y., Wen, H., Qian,Z., Zhang, C., Hong, L., Yang, H., Zhang, J.,Tong, Z., Wang, W., Chen, X.,& Mao, Z.

https://doi.org/10.1038/s41565-023-01346-x

992. Iron-siRNA Nanohybrids for EnhancedChemodynamic Therapy via Ferritin Heavy Chain Downregulation.

Angewandte Chemie (International ed. in English), e202302255. Advance online publication.

Wang, J., Ding, H., Zhu, Y., Liu, Y., Yu, M., Cai,H., Ao, R., Huang, H., Gong, P., Liao, Y., Chen, Z., Lin, L., Chen, X., &Yang, H.

https://doi.org/10.1002/anie.202302255

991. Engineered Toll-like Receptor NanoagonistBinding to Extracellular Matrix Elicits Safe and Robust Antitumor Immunity.

ACS nano, 2023, 17(6), 5340–5353.

Yang, L., Lang, Y., Wu, H., Xiang, K., Wang, Y., Yu,M., Liu, Y., Yang, B., He, L., Lu, G., Ni, Q., Chen, X., & Zhang, L.

https://doi.org/10.1021/acsnano.2c08429

990. Harnessing Nanomaterials for CancerSonodynamic Immunotherapy.

Advanced materials (Deerfield Beach, Fla.), e2211130. Advance online publication.

Liang, S., Yao, J., Liu, D., Rao, L., Chen, X., &Wang, Z. (2023).

https://doi.org/10.1002/adma.202211130

989. Ferroptosis MRI for early detection ofanticancer drug-induced acute cardiac/kidney injuries.

Science advances, 9(10), eadd8539.

Zeng, F., Nijiati, S., Liu, Y., Yang, Q., Liu, X.,Zhang, Q., Chen, S., Su, A., Xiong, H., Shi, C., Cai, C., Lin, Z., Chen, X.,& Zhou, Z.

https://doi.org/10.1126/sciadv.add8539

988. In Situ Transformable Nanoplatforms withSupramolecular Crosslinking Triggered Complementary Function for EnhancedCancer Photodynamic Therapy.

Advanced materials (Deerfield Beach, Fla.), 2023, e2209944. Advance online publication.

Zhao, M., Zhuang, H., Li, B., Chen, M., & Chen,X.

https://doi.org/10.1002/adma.202209944

987. Transition Metal-based Therapies forInflammatory Diseases.

Advanced materials (Deerfield Beach, Fla.), 2023, e2212102. Advance online publication.

Song, Y., You, Q., & Chen, X.

https://doi.org/10.1002/adma.202212102

986. Exosomal STIMATE derived from type IIalveolar epithelial cells controls metabolic reprogramming of tissue-residentalveolar macrophages.

Theranostics, 13(3), 991–1009.

Feng, Z., Jing, Z., Li, Q., Chu, L., Jiang, Y.,Zhang, X., Yan, L., Liu, Y., Jiang, J., Xu, P., Chen, Q., Wang, M., Yang, H.,Zhou, G., Jiang, X., Chen, X., & Xia, H.

https://doi.org/10.7150/thno.82552

985. Ferroptosis Detection: From Approaches toApplications

Angewandte Chemie (International ed. in English), e202300379. Advance online publication.

Zeng, F., Nijiati, S.,Tang, L., Ye, J., Zhou, Z.,& Chen, X.

https://doi.org/10.1002/anie.202300379

984. Ultra-wideband-responsive photon conversionthrough co-sensitization in lanthanide nanocrystals.

Nature communications, 14(1), 827.

Jiang, Z., He, L., Yang, Z., Qiu, H., Chen, X., Yu,X., & Li, W.

https://doi.org/10.1038/s41467-023-36510-3

983. Boosting Checkpoint Immunotherapy withBiomaterials.

ACS Nano. 2023 Feb 6. doi: 10.1021/acsnano.2c11691.

Liu L, PaY, Zhao C, Huang P, Chen X, Rao L.

https://pubs.acs.org/doi/10.1021/acsnano.2c11691

982. Peptide Receptor Radionuclide Therapy inPatients With Advanced Progressive Medullary Thyroid Cancer: Efficacy, Safety,and Survival Predictors.

Clin Nucl Med. 2023 Mar 1;48(3):221-227.

Liu Q, Kulkarni HR, Zhao T, Schuchardt C, Chen X, ZhuZ, Zhang J, Baum RP.

https://journals.lww.com/nuclearmed/Abstract/2023/03000/Peptide_Receptor_Radionuclide_Therapy_in_Patients.3.aspx

981. Vesicular Antibodies: Shedding Light onAntibody Therapeutics with Cell Membrane Nanotechnology.

Adv Mater. 2023 Jan 31:e2207875.

Zhao C, Pan Y, Yu G, Zhao XZ, Chen X, Rao L.

https://onlinelibrary.wiley.com/doi/10.1002/adma.202207875

980. Boosting Ferroptosis Therapy with IridiumSingle Atom Nanocatalyst in Ultra-low Metal Content.

Adv Mater. 2023 Jan 31:e2210037.

Cheng J, Li L, Jin D, Dai Y, Zhu Y, Zou J, Liu M, YuW, Yu J, Sun Y, Chen X, Liu Y.

https://onlinelibrary.wiley.com/doi/10.1002/adma.202210037

979. Amplification of Lipid Peroxidation byRegulating Cell Membrane Unsaturation to Enhance Chemodynamic Therapy.

Angew Chem Int Ed Engl. 2023 Jan 28.

Zhu Y, Gong P, Wang J, Cheng J, Wang W, Cai H, Ao R,Huang H, Yu M, Lin L, Chen X.

https://onlinelibrary.wiley.com/doi/10.1002/anie.202218407

978. Fluorescence Imaging-IncorporatedTranscriptome Study of Glutathione Depletion-Enhanced Ferroptosis Therapy viaTargeting Gold Nanoclusters.

ACS Appl Mater Interfaces. 2023 Jan 27. doi: 10.1021/acsami.2c18289.

Zhao D, Huang X,Tian Y, Zou J, Wang F, Chen X.

https://pubs.acs.org/doi/10.1021/acsami.2c18289

977. Enhancing Catalytic Activity of a NickelSingle Atom Enzyme by Polynary Heteroatom Doping for Ferroptosis-Based TumorTherapy.

ACS Nano. 2023 Jan 16. doi: 10.1021/acsnano.2c11923.

Zhu Y, Wang W, Gong P, Zhao Y, Pan Y, Zou J, Ao R,Wang J, Cai H, Huang H, Yu M, Wang H, Lin L, Chen X, Wu Y.

https://pubs.acs.org/doi/10.1021/acsnano.2c11923

976. Tumor polyamines as guest cues attracthost-functionalized liposomes for targeting and hunting via a bio-orthogonalsupramolecular strategy

Theranostics. 2023 Jan 1;13(2):611-620.

Cheng Q, Yang Z, Quan X, Ding Y, Li J, Wang Z, Zhao Y,Chen X, Wang R.

https://www.thno.org/v13p0611.htm

 

974. Alpha-peptide receptor radionuclide therapyusing actinium-225 labeled somatostatin receptor agonists and antagonists

Front Med(Lausanne). 2022 Dec 7;9:1034315

Mengqi Shi,Vivianne Jakobsson, Lukas Greifenstein, Pek-Lan Khong, Xiao yuan Chen, RichardP Baum, Jingjing Zhang

https://www.frontiersin.org/articles/10.3389/fmed.2022.1034315/full

973. PET imaging of fibroblast activation proteinin various types of cancers by using 68Ga-FAP-2286: Comparison with 18F-FDG and68Ga-FAPI-46 in a single-center, prospective study.

J Nucl Med. 2022 Sep2:jnumed.122.264544.

Pang Y, Zhao L,Meng T, Xu W, Lin Q, Wu H, Zhang J, Chen X, Sun L, Chen H.

https://jnm.snmjournals.org/content/early/2022/09/01/jnumed.122.264544.long

972. Synergism of 64Cu-Labeled RGD with Anti-PD-L1Immunotherapy for the Long-Acting Antitumor Effect.

Bioconjug Chem. 2022 Nov16;33(11):2170-2179.

Wen X, Zeng X, LiuJ, Zhang Y, Shi C, Wu X, Zhuang R, Chen X, Zhang X, Guo Z.

https://pubs.acs.org/doi/10.1021/acs.bioconjchem.2c00408

971. Development of a multi-scene universalmultiple wavelet-FFT algorithm (MW-FFTA) for denoising motion artifacts inOCT-angiography in vivo imaging.

Opt Express. 2022 Sep26;30(20):35854-35870.

Zhang Y, Li J, LiuC, Zheng K, Zhang B, Zhou Y, Dai C, Fan S, Yao Y, Zhuang R, Guo D, Huang Z, MaoJ, Liang J, Yang H, Wang L, Liu G, Chen X, Zhao Q.

https://opg.optica.org/oe/viewmedia.cfm?uri=oe-30-20-35854&html=true

970. A Totipotent "All-In-One" PeptideSequentially Blocks Immune Checkpoint and Reverses the Immunosuppressive TumorMicroenvironment.

Adv Mater. 2022 Oct19:e2207330.

Zhang L, Jiang Z, YangX, Qian Y, Wang M, Wu S, Li L, Jia F, Wang Z, Hu Z, Zhao M,Tang X, Li G, ShangH, Chen X, Wang W.

https://onlinelibrary.wiley.com/doi/10.1002/adma.202207330

969. Near-infrared-II ratiometric fluorescenceprobes for non-invasive detection and precise navigation surgery of metastaticsentinel lymph nodes.

Theranostics. 2022 Oct9;12(16):7191-7202.

Li M, Zheng X, HanT, Ma S, Wang Y, Sun B, Xu J, Wang X, Zhang S, Zhu S, Chen X.

https://www.thno.org/v12p7191.htm

968. Synthesis, preclinical evaluation andradiation dosimetry of a dual targeting PET tracer [68Ga]Ga-FAPI-RGD.

Theranostics. 2022 Oct9;12(16):7180-7190.

Zang J, Wen X, LinR, Zeng X, Wang C, Shi M, Zeng X, Zhang J, Wu X, Zhang X, Miao W, Xu P, Guo Z,Zhang J, Chen X.

https://www.thno.org/v12p7180.htm

967. Cell Wall Destruction and Internal CascadeSynergistic Antifungal Strategy for Fungal Keratitis.

ACS Nano. 2022 Nov22;16(11):18729-18745.

Ye Y, He J, WangH, Li W, Wang Q, Luo C, Tang X, Chen X, Jin X, Yao K, Zhou M.

https://pubs.acs.org/doi/10.1021/acsnano.2c07444

966. BiomimeticYolk-Shell Nanocatalysts forActivatable Dual-Modal-Image-Guided Triple-Augmented Chemodynamic Therapy ofCancer.

ACS Nano. 2022 Nov22;16(11):19038-19052.

Pan Y, Zhu Y, XuC, Pan C, Shi Y, Zou J, Li Y, Hu X, Zhou B, Zhao C, Gao Q, Zhang J, Wu A, ChenX, Li J.

https://pubmed.ncbi.nlm.nih.gov/36315056/

965. An Integrated Polymeric mRNA Vaccine withoutInflammation Side Effects for Cellular Immunity Mediated Cancer Therapy.

Adv Mater. 2022 Nov3:e2207471

Huang P, Jiang L,Pan H, Ding L, Zhou B, Zhao M, Zou J, Li B, Qi M, Deng H, Zhou Y, Chen X.

https://onlinelibrary.wiley.com/doi/10.1002/adma.202207471

964. A single-arm, low-dose, prospective study of177Lu-EB-PSMA radioligand therapy in patients with metastaticcastration-resistant prostate cancer.

J Nucl Med. 2022 Nov3:jnumed.122.264857.

Wang G, Zang J,Jiang Y, Liu Q, Sui H, Wang R, Fan X, Zhang J, Zhu Z, Chen X.

https://pubmed.ncbi.nlm.nih.gov/36328486/

963. Development of nanotechnology-mediatedprecision radiotherapy for anti-metastasis and radioprotection.

Chem Soc Rev. 2022 Nov28;51(23):9759-9830.

Pan Y,Tang W, FanW, Zhang J, Chen X.

https://pubmed.ncbi.nlm.nih.gov/36354107/

962. Responsive Accumulation of Nanohybrids toBoost NIR-Phototheranostics for Specific Tumor Imaging and GlutathioneDepletion-Enhanced Synergistic Therapy.

Adv Sci (Weinh). 2022 Nov14;10(1):e2205208.

He L, Zheng N,Wang Q, Du J, Wang S, Cao Z, Wang Z, Chen G, Mu J, Liu S, Chen X.

https://pubmed.ncbi.nlm.nih.gov/36373690/

961. Facile Synthesis of Weakly FerromagneticOrganogadolinium Macrochelates-Based T1 -Weighted Magnetic Resonance ImagingContrast Agents.

Adv Sci (Weinh). 2022 Nov15;10(1):e2205109.

Lu Y, Liang Z,Feng J, Huang L, Guo S, Yi P, Xiong W, Chen S, Yang S, Xu Y, Li Y, Chen X, ShenZ.

https://pubmed.ncbi.nlm.nih.gov/36377432/

960. In Response to Precision Medicine: CurrentSubcellular Targeting Strategies for Cancer Therapy.

Adv Mater. 2022 Nov29:e2209529

Li Z, Zou J, ChenX.

https://pubmed.ncbi.nlm.nih.gov/36445169/

959.Targeting the activity of T cells by membranesurface redox regulation for cancer theranostics

Nat Nanotechnol. 2022 Dec 19. doi:10.1038/s41565-022-01261-7

Shi C, Zhang Q, YaoY, Zeng F, Du C, Nijiati S, Wen X, Zhang X, Yang H, Chen H, Guo Z, Zhang X, GaoJ, Guo W, Chen X, Zhou Z.Targeting the activity of T cells by

membrane surfaceredox regulation for cancer theranostics. Nat Nanotechnol. 2022 Dec 19. doi:10.1038/s41565-022-01261-7. Epub ahead of print. PMID: 36536041.

https://www.nature.com/articles/s41565-022-01261-7

958. Evolution of drug regulations and regulatoryinnovation for anticancer drugs in China.

Acta Pharm Sin B. 2022Dec;12(12):4365-4377

Liu Y, Zhang N,Xie C, Jiang Y, QinY, Zhou L, Fan Y, Ren L, Yin C, Yang H, Xie W, Zhai Q, Li G,Chen H, Chen X.

https://pubmed.ncbi.nlm.nih.gov/36561995/

957. Safety and efficacy of peptide receptorradionuclide therapy with 177Lu-DOTA-EB-TATE in patients with metastaticneuroendocrine tumors

Theranostics 2022;12(15):6437-6445.

Jiang Y, Liu Q,Wang G, Sui H, Wang R, Wang J, Zhang J, Zhu Z, Chen X.

https://www.thno.org/v12p6437.htm

956. Organic phosphorescent nanoscintillator forlow-dose X-ray-induced photodynamic therapy.

Nat Commun. 2022;13(1):5091.

Wang X, Sun W, ShiH, Ma H, Niu G, Li Y, Zhi J, Yao X, Song Z, Chen L, Li S, Yang G, Zhou Z, He Y,Qu S, Wu M, Zhao Z, Yin C, Lin C, Gao J, Li Q, Zhen X, Li L, Chen X, Liu X, AnZ, Chen H, Huang W.

https://www.nature.com/articles/s41467-022-32054-0

955. Targeting the activity of T cells by membranesurface redox regulation for cancer theranostics

Nat Nanotechnol, in press.

Shi C, Zhang Q,Zeng F, Du C, Nijiati S, Wen X, Yang H, Guo Z, Zhang X, Gao J, Chen X, Zhou Z

954. A pilot study of 68 Ga-PSMA-617 PET/CTimaging and 177Lu-EB-PSMA-617 radioligand therapy in patients with adenoidcystic carcinoma.

EJNMMI Res. 2022 Aug19;12(1):52.

Wang G, Zhou M,Zang J, Jiang Y, Chen X, Zhu Z, Chen X.

https://link.springer.com/article/10.1186/s13550-022-00922-x

953. Combined 18F-FDG and 18F-Alfatide II PET MayPredict Luminal B (HER2 Negative) Subtype and Nonluminal Subtype of InvasiveBreast Cancer.

Mol Pharm. 2022 Aug 16. doi:10.1021/acs.molpharmaceut.2c00547.

Wu J, Zhang X, JiaZ, Zhou X, Qi R, Ji H, Sun J, Sun C,Teng Z, Lu G, Chen X.

https://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.2c00547

952. Cancer Nanomedicine

Nat Rev Cancer, doi:10.1038/s41568-022-00496-9

Bhatia S, Chen X,Dobrovolskaia M, Lammers T

https://www.nature.com/articles/s41568-022-00496-9

951. Management of fluorescent organic/inorganicnanohybrids for biomedical applications in the NIR-II region

Chem Soc Rev, DOIhttps://doi.org/10.1039/D2CS00131D

Li B, Zhao M, LinJ, Huang P, Chen X

https://pubs.rsc.org/en/content/articlehtml/2022/cs/d2cs00131d

950. Microfluidics-Assisted Fluorescence Mappingof DNA Phosphorothioation

Anal Chem, 2022 Jul26;94(29):10479-10486

Huang Q, Chen X,Meng Q-F, Yue L, Jiang W, Zhao X-Z, Rao L, Chen X, S chen

https://pubs.acs.org/doi/abs/10.1021/acs.analchem.2c01752

949. Harnessing Immune Response Using ReactiveOxygen Species-Generating/Eliminating Inorganic Biomaterials for DiseaseTreatment

Adv Drug DelivRev, 2022 Jul 16;188:114456

Zhao C, Deng H,Chen X

https://www.sciencedirect.com/science/article/abs/pii/S0169409X22003465

948. Super-stable cyanine@albumin fluorophore forenhanced NIR-II bioimaging

Theranostics. 2022 May26;12(10):4536-4547

Bai L, Hu Z, HanT, Wang Y, Xu J, Jiang G, Feng X, Sun B, Liu X,Tian R, Sun H, Zhang S, Chen X,Zhu S.

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947. Nanomaterial-Mediated Ablation Therapy forCancer Stem Cells

Matter, 2022;5:1367-1390.

Pan Y, Liu L, RaoL, Chen X

https://www.sciencedirect.com/science/article/abs/pii/S2590238522000662

946. Chiral gold clusters functionalizedtwo-dimensional nanoparticle films to regulate the adhesion and differentiationof stem cells

J ColloidInterface Sci. 2022;625:831-838.

Kang X, Wang Y,Cai XL, Hua Y, Shao ZH, Chen X, Zhao X, Zang SQ.

https://www.sciencedirect.com/science/article/abs/pii/S0021979722010529

945. Cucurbituril-based Supramolecular Polymersfor Biomedical Applications

Angew Chem Int EdEngl. 2022 Jun 28. doi: 10.1002/anie.202206763.

Wang Z, Sun C, YangK, Chen X, Wang R.

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944.The Roles of Polymers in mRNA Delivery

Matter, 2022;5:1670-1699.

Huang P, Deng H,Zhou Y, Chen X

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943. Levonorgestrel-protected Au8 and Au10clusters with different antimicrobial abilities

J Mater Chem B. 2022 Jun 20. doi:10.1039/d2tb00533f.

Wang Y, Hua Y,Shao ZH, Chen X, Zhao X, Zang SQ.

https://pubs.rsc.org/en/content/articlelanding/2022/tb/d2tb00533f/unauth

942. Composition-Dependent Enzyme MimickingActivity and Radiosensitizing Effect of Bimetallic Clusters to Modulate TumorHypoxia for Enhanced

Cancer Therapy

Adv Mater. 2022:e2203734.

Hua Y, Huang JH,Shao ZH, Luo XM, Wang ZY, Liu JQ, Zhao X, Chen X, Zang SQ.

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941. PD-L1-Targeted Radionuclide Therapy Combinedwith αPD-L1 Antibody Immunotherapy Synergistically Improves the AntitumorEffect

Mol Pharm. 2022 Jun 2. doi:10.1021/acs.molpharmaceut.2c00281.

Wen X, Zeng X,Cheng X, Zeng X, Liu J, Zhang Y, Li Y, Chen H, Huang J, Guo Z, Chen X, Zhang X.

https://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.2c00281

940. Rational Design and Pharmacomodulation ofProtein-Binding Theranostic Radioligands for Targeting the FibroblastActivation Protein

J Med Chem. 2022 Jun 5. doi:10.1021/acs.jmedchem.1c02162.

Meng L, Fang J,Zhao L, Wang T, Yuan P, Zhao Z, Zhuang R, Lin Q, Chen H, Chen X, Zhang X, GuoZ.

https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.1c02162

939. A genetic engineering strategy for editingnear-infrared-II fluorophores.

Nat Commun. 2022 May23;13(1):2853.

Tian R, Feng X,Wei L, Dai D, Ma Y, Pan H, Ge S, Bai L, Ke C, Liu Y, Lang L, Zhu S, Sun H, Yu Y,Chen X.

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938. Protective Effect of PlatinumNano-antioxidant and Nitric Oxide Against Hepatic Ischemia-Reperfusion Injury

Nat Commun, 2022;13(1):2513

Mu J, Li C, Shi Y,Liu G, Zou J, Zhang D, Jiang C, Wang X, He L, Huang P, Yin Y, Chen X

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937. Reactive Oxygen Species ScavengingNanomedicine for The Treatment of Ischemic Heart Disease

Adv Mater. 2022:e2202169.

Zhang Z, Dalan R,Hu Z, Wang JW, Chew NW, Poh KK,Tan RS, Soong TW, Dai Y, Ye L, Chen X.

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936. Photoacoustic Imaging-Guided SynergisticPhotothermal/Radiotherapy Using Plasmonic Bi/Bi2O3-x Nanoparticles

Adv Funct Mater, https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.202113353

Huang X, Zha F,Zou J, Li Y, Wang F, Chen X

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935. Smart Mushroom-Inspired Imprintable andLightly Detachable (MILD) Microneedle Patterns for Effective COVID-19Vaccination and Decentralized

Information Storage

ACS Nano. 2022 Apr 22. doi:10.1021/acsnano.1c10718.

Li Q, Xu R, Fan H,Xu J, Xu Y, Cao P, Zhang Y, Liang T, Zhang Y, Chen W, Wang Z, Wang L, Chen X

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934. A nanovaccine for antigen self-presentationand immunosuppression reversal as a personalized cancer immunotherapy strategy

Nat Nanotechnol. 2022 Apr 11. doi:10.1038/s41565-022-01098-0.

Liu C, Liu X,Xiang X, Pang X, Chen S, Zhang Y, Ren E, Zhang L, Liu X, Lv P, Wang X, Luo W,Xia N, Chen X, Liu G

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933.Avoiding the self-nucleation interference: apH-regulated gold in situ growth strategy to enable ultrasensitiveimmunochromatographic diagnostics

Theranostics. 2022;12(6):2801-2810.

Duan H, Ma T,Huang X, Gao B, Zheng L, Chen X, Xiong Y, Chen X

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932. Combined Probe Strategy to Increase theEnzymatic Digestion Rate and Accelerate the Renal Radioactivity Clearance ofPeptide Radiotracers

Mol Pharm. 2022 Mar 31. doi:10.1021/acs.molpharmaceut.2c00051.

Zhang M, Ye J, XieZ, Wang Y, Ma W, Kang F, Yang W, Wang J, Chen X

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931. A paradigm of cancer immunotherapy based on2-[18F]FDG and anti-PD-L1 mAb combination to enhance the anti-tumor effect

Clin Cancer Res. 2022 Mar23:clincanres.0159.2022.

Wen X, Shi C, ZengX, Zhao L, Yao L, Liu Z, Feng L, Zhang D, Huang J, Li Y, Lin Q, Chen H, ZhuangR, Chen X, Zhang X, Guo Z.

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930.Preliminary Clinical Application ofRGD-Containing Peptides as PET Radiotracers for Imaging Tumors

Front Oncol. 2022;12:837952.

Li L, Chen X, YuJ, Yuan S.

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929. A tumor microenvironment dual responsivecontrast agent for contrary contrast-magnetic resonance imaging and specificchemotherapy of tumors

Nanoscale Horiz. 2022 Feb 25. doi:10.1039/d1nh00632k.

Lu Y, Feng J,Liang Z, Lu X, Guo S, Huang L, Xiong W, Chen S, Zhou H, Ma X, Xu Y, Qiu X, WuA, Chen X, Shen Z.

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928. A super-stable homogeneousLipiodol-hydrophilic chemodrug formulation for treatment of hepatocellularcarcinoma

Theranostics. 2022;12(4):1769-1782.

He P, Ren E, ChenB, Chen H, Cheng H, Gao X, Liang X, Liu H, Li J, Li B, Chen A, Chu C, Chen X,Mao J, Zhang Y, Liu G.

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927. Recent advances in biomaterial-boostedadoptive cell therapy

Chem Soc Rev. 2022 Feb 16. doi:10.1039/d1cs00786f.

Xue Y, Che J, JiX, Li Y, Xie J, Chen X.

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926. A "Self-Checking"pH/Viscosity-Activatable NIR-II Molecule for Real-Time Evaluation ofPhotothermal Therapy Efficacy

Angew Chem Int EdEngl. 2022 Feb 15. doi: 10.1002/anie.202200025.

Li B, Liu H, He Y,Zhao M, Ge C, Younis MR, Huang P, Chen X, Lin J.

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925. Antibody-Incorporated Nanomedicines forCancer Therapy

Adv Mater. 2022 Feb10:e2109210. doi: 10.1002/adma.202109210.

Wu SY, Wu FG, ChenX.

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924. 18F-Alfatide II for the evaluation ofaxillary lymph nodes in breast cancer patients: comparison with 18F-FDG

Eur J Nucl Med MolImaging. 2022 Feb 9. doi: 10.1007/s00259-021-05333-z.

Wu J,Tian J, ZhangY, Ji H, Sun J, Wang X, Sun C, Wang L,Teng Z, Lu G, Zhu H, Chen X.

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923. Noninvasive Dual-ModalityPhotoacoustic-Ultrasonic Imaging to Detect Mammalian Embryo Abnormalities afterPrenatal Exposure to Methylmercury Chloride (MMC): A Mouse Study

Environ HealthPerspect. 2022;130(2):27002.

Qiu Q, Huang Y,Zhang B, Huang D, Chen X, Fan Z, Lin J,Yang W, Wang K, Qu N, Li J, Li Z, HuangJ, Li S, Zhang J, Liu G, Rui G, Chen X, Zhao Q

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922. Hybrid Membrane-Decorated Prussian Blue forEffective Cancer Immunotherapy via Tumor-Associated Macrophages Polarizationand Hypoxia

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Hou L, Gongu X,Zhang JH, Yang W, Chen X

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921. Metal-free bioorthogonal click chemistry incancer theranostics

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Wu D, Yang K,Zhang Z, Feng Y, Rao L, Chen X, Yu G.

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920. Evans blue-modified radiolabeled fibroblastactivation protein inhibitor as long-acting cancer therapeutics

Theranostics.2022;12(1):422-433.

Wen X, Xu P, ShiM, Liu J, Zeng X, Zhang Y, Shi C, Li J, Guo Z, Zhang X, Khong PL, Chen X.

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919. Near-infrared probes for luminescencelifetime imaging

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Li B, Lin J, HuangP, Chen X.

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918. Coordinating the mechanism of actions offerroptosis and photothermal effect for cancer theranostics

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Zeng F,Tang L,Zhang Q, Shi C, Huang Z, Nijiati S, Chen X, Zhou Z.

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917. Biodegradable Metal-Organic Framework-GatedOrganosilica for Tumor Microenvironment-Unlocked Glutathione Depletion-EnhancedSynergistic

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916. Prostate-specific membrane antigenradioligand therapy using 177Lu-PSMA I&T and 177Lu-PSMA-617 in patientswith metastatic castration[1]resistantprostate cancer: comparison of safety, biodistribution and dosimetry

J Nucl Med. 2021 Dec9:jnumed.121.262713. doi: 10.2967/jnumed.121.262713.

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915. The Chemistry of Organic Contrast Agents inthe NIR-II Window

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Mu J, Xiao M, Shi Y,Geng X, Li H, Yin Y, Chen X.

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914. Nanomaterials targeting tumor associatedmacrophages for cancer immunotherapy

Zhao C, Pang X, YangZ, Wang S, Deng H, Chen X

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912. A multifunctional AIE gold cluster-basedtheranostic system: tumor-targeted imaging and Fenton reaction-assistedenhanced radiotherapy

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Hua Y, Wang Y,Kang X, Xu F, Han Z, Zhang C, Wang ZY, Liu JQ, Zhao X, Chen X, Zang SQ.

 

911. Multi-Responsive Bottlebrush-LikeUnimolecules Self-Assembled Nano-Riceball for Synergistic SonoChemotherapy

Small Methods. 2021;5(3):e2000416.

Shi X, Zhang Y,TianY, Xu S, Ren E, Bai S, Chen X, Chu C, Xu Z, Liu G

 

910. Repurposing ICG enables MR/PA imaging signalamplification and iron depletion for iron-overload disorders

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Lin H, Zhou Y,Wang J, Wang H, Yao T, Chen H, Zheng H, Zhang Y, Ren E, Jiang L, Chu C, Chen X,Mao J, Wang F, Liu G.

 

909. NIR-II emissive AIEgen photosensitizersenable ultrasensitive imaging-guided surgery and phototherapy to fully inhibitorthotopic hepatic tumors

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Jia R, Xu H, WangC, Su L, Jing J, Xu S, Zhou Y, Sun W, Song J, Chen X, Chen H.

 

908. Ligand Engineering of Titanium-OxoNanoclusters for Cerenkov Radiation-Reinforced Photo/Chemodynamic Tumor Therapy

ACS Appl MaterInterfaces. 2021;13(46):54727-54738.

Li J, Dai S, QinR, Shi C, Ming J, Zeng X, Wen X, Zhuang R, Chen X, Guo Z, Zhang X.

 

907. Redox-Activated Contrast-Enhanced T1-WeightedImaging Visualizes Glutathione-Mediated Biotransformation Dynamics in the Liver

ACS Nano. 2021;15:17831-17841.

Liu K, Kang B, LuoX, Yang Z, Sun C, Li A, Fan Y, Chen X, Gao J, Lin H.

 

906. Aptamer-based biosensors and application intumor theranostics

Cancer Sci. 2022;113:7-16.

Mo T, Liu X, Luo Y,Zhong L, Zhang Z, Li T, Gan L, Liu X, Li L, Wang H, Sun X, Fan D, Qian Z, Wu P,Chen X.

 

905. Intelligent Pore Switch of Hollow MesoporousOrganosilica Nanoparticles for High Contrast Magnetic Resonance Imaging andTumor-Specific

Chemotherapy

Nano Lett.2021;21(22):9551-9559.

Huang L, Feng J,Fan W,Tang W, Rong X, Liao W, Wei Z, Xu Y, Wu A, Chen X, Shen Z.

 

904. Polyprodrug Nanomedicines: An Emerging Paradigm forCancer Therapy

Adv Mater. 2021 Oct25:e2107434.

Yang K, Yang Z, YuG, Nie Z, Wang R, Chen X.

 

903. Somatostatin receptor imaging with[68Ga]Ga-DOTATATE positron emission tomography/computed tomography (PET/CT) inpatients with nasopharyngeal carcinoma

Eur J Nucl Med MolImaging. 2021 Oct 19. doi: 10.1007/s00259-021-05587-7.

Zhao L, Pang Y,Wang Y, Chen J, Zhuang Y, Zhang J, Zhao L, Sun L, Wu H, Chen X, Lin Q, Chen H.

 

902. Genetically Programmable Fusion CellularVesicles for Cancer Immunotherapy

Angew Chem Int EdEngl. 2021;60(50):26320-26326.

Meng QF, Zhao Y,Dong C, Liu L, Pan Y, Lai J, Liu Z, Yu GT, Chen X, Rao L.

 

901. Smart Chemical Engineering-based Lightweightand Miniaturized Attachable Systems for Advanced Drug Delivery and Diagnostics

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Chen W, Wang Z,Wang L, Chen X.

 

900. Radioiodinated 4-(p-Iodophenyl) ButanoicAcid-Modified Estradiol Derivative for ER Targeting SPECT Imaging

Anal Chem.2021;93(41):13998-14006.

Xu D, Lin X, ZengX, Wen X, Li J, Li Y, Huang J, Chen X, Guo Z, Zhang X.

 

899. Lung-Targeting Lysostaphin Microspheres forMethicillin-Resistant Staphylococcus aureus Pneumonia Treatment and Prevention

ACS Nano. 2021;15(10):16625-16641.

Lin X, He J, Li W,Qi Y, Hu H, Zhang D, Xu F, Chen X, Zhou M.

 

898. Manipulating Intratumoral Fenton Chemistryfor Enhanced Chemodynamic and ChemodynamicSynergized Multimodal Therapy

Adv Mater. 2021 Sep27:e2104223.

Zhou Y, Fan S,Feng L, Huang X, Chen X.

 

897. Singlet Oxygen "Afterglow" Therapywith NIR-II Fluorescent Molecules

Adv Mater. 2021 Sep13:e2103627.

Zou J, Li L, ZhuJ, Li X, Yang Z, Huang W, Chen X.

 

896. Optimization of Enzymolysis ClearanceStrategy To Enhance Renal Clearance of Radioligands

Bioconjug Chem. 2021 Sep 6. doi:10.1021/acs.bioconjchem.1c00392.

Zhang M, Ye J, XieZ, Yan Y, Wang J, Chen X.

 

895.Endogenous dual stimuli-activated NOgeneration in the conventional outflow pathway for precision glaucoma therapy

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Fan W, Song M, LiL, Niu L, Chen Y, Han B, Sun X,Yang Z, Lei Y, Chen X.

 

894.Milk-derived extracellular vesicles alleviateulcerative colitis by regulating the gut immunity and reshaping the gutmicrobiota

Theranostics. 2021;11(17):8570-8586.

Tong L, Hao H,Zhang Z, Lv Y, Liang X, Liu Q, Liu T, Gong P, Zhang L, Cao F, Pastorin G, LeeCN, Chen X, Wang JW, Yi H.

 

893. Fluorescence imaging of pathophysiologicalmicroenvironments.

Chem Soc Rev. 2021 Jul 1. doi:10.1039/d1cs00083g.

Wang S, Ren WX,Hou JT, Won M, An J, Chen X, Shu J, Kim JS.

 

892. Exquisite vesicular nanomedicine bypaclitaxel mediated co-assembly with camptothecin prodrug.

Angew Chem Int EdEngl. 2021 Jul 18. doi: 10.1002/anie.202108658.

Zhou Z, Du C,Zhang Q, Yu G, Zhang F, Chen X.

 

891. Antiangiogenesis Combined with Inhibition ofthe Hypoxia Pathway Facilitates Low-Dose, X-rayInduced Photodynamic Therapy

ACS Nano. 2021 Jun 25. doi:10.1021/acsnano.1c01063.

Jiang Z, He L, YuX, Yang Z, Wu W, Wang X, Mao R, Cui D, Chen X, Li W.

 

890. Intravital Whole-Process MonitoringThermo-Chemotherapy Via 2D Silicon Nanoplatform: A Macro Guidance and Long-TermMicroscopic Precise Imaging Strategy

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Huang D, Wang G,Mao J, Liu C, Fan Z, Zhang Y, Zhang B, Zhao Y, Dai C, He Y, Ma H, Liu G, ChenX, Zhao Q.

 

889. Mn3+-rich oxide/persistent luminescencenanoparticles achieve light-free generation of singlet oxygen and hydroxylradicals for responsive

imaging and tumor treatment

Theranostics. 2021 May25;11(15):7439-7449.

Ding D, FengY, QinR, Li S, Chen L, Jing J, Zhang C, Sun W, LiY, Chen X, Chen H.

 

888. Functional Micro-/Nanomaterials forMultiplexed Biodetection

Adv Mater. 2021 Jun17:e2004734.

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887. 68Ga-NOTA-Evans Blue PET/CT findings inlymphangioleiomyomatosis compared with 99mTC-ASC lymphoscintigraphy: aprospective study.

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Hou G, JiangY, XuW, Zhu Z, Huo L, Chen X, Li F, Xu KF, Cheng W.

 

886. Synthesis and Bioapplications of Ag2S QuantumDots with Near-Infrared Fluorescence

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Ding C, Huang Y,Shen Z, Chen X

 

885. A Fluorinated Ionic Liquid-Based Activatable19F MRI Platform Detects Biological Targets

Chem. 2020 May14;6(5):1134-1148.

Zhu X,Tang X, LinH, Shi S, Xiong H, Zhou Q, Li A, Wang Q, Chen X, Gao J.

 

884. A hypoxia responsive nanoassembly for tumorspecific oxygenation and enhanced sonodynamic therapy

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Yang K, Yue L, YuG, Rao L,Tian R, Wei J, Yang Z, Sun C, Zhang X, Xu M, Yuan Z, Chen X, Wang R.

 

883. Supramolecular Polymerization-InducedNanoassemblies for Self-Augmented Cascade Chemotherapy and Chemodynamic Therapyof Tumour

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Yang K, Yang Z, YueL, Yu G, Zhang X, Sun C, Wei J, Rao L, Chen X, Wang R.

 

882. Photodynamic-Chemodynamic Cascade Reactionsfor Efficient Drug Delivery and Enhanced Combination Therapy

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881. Extracellular vesicles as a drug deliverysystem:A systematic review of preclinical studies

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880. Beyond Photo: Xdynamic Therapies in FightingCancer.

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879. Bombesin-Tethered Reactive Oxygen Species(ROS)-Responsive Nanoparticles for Monomethyl Auristatin F (MMAF) Delivery

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878. Capturing Cytokines with Advanced Materials:A Potential Strategy to Tackle COVID-19 Cytokine Storm

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7. Meng QF,Tian R,Long H, Wu X, Lai J, Zharkova O, Wang JW, Chen X, Rao L.

 

877. Singlet Oxygen Generation in Dark-Hypoxia byCatalytic Microenvironment-Tailored Nanoreactors for NIR-IIFluorescence-Monitored

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Chen T, Hou P,Zhang Y, Ao R, Su L, Jiang Y, Zhang Y, Cai H, Wang J, Chen Q, Song J, Lin L, YangH, Chen X.

 

876. Polyphenol-Containing Nanoparticles:Synthesis, Properties, and Therapeutic Delivery

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875. Rationally Programming Nanomaterials with DNAfor Biomedical Applications

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874. Biphasic synthesis of biodegradableurchin-like mesoporous organosilica nanoparticles for enhanced cellularinternalization and precision cascaded therapy

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873. Targeted Dual Small Interfering RibonucleicAcid Delivery via Non-Viral Polymeric Vectors for Pulmonary Fibrosis Therapy

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872. Supramolecular cancer nanotheranostics.

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Zhou J, Rao L, YuG, Cook TR, Chen X, Huang F.

 

871. Pnictogen Semimetal (Sb, Bi)-BasedNanomaterials for Cancer Imaging and Therapy: A Materials Perspective

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870. A hybrid semiconducting organosilica-based O2nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy

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869. 177Lu-DOTA-EB-TATE, a Radiolabeled Analogueof Somatostatin Receptor Type 2, for the Imaging and Treatment of ThyroidCancer

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868. Stimuli-Responsive Plasmonic Assemblies andTheir Biomedical Applications.

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867. Imaging of Insulinoma by TargetingGlucagonlike Peptide-1 Receptor.

PET Clin. 2021 Feb12:S1556-8598(20)30103-6.

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866. Resection and survival data from a clinicaltrial of glioblastoma multiforme-specific IRDye800-BBN fluorescence-guidedsurgery.

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865. Supramolecular coordination complexes asdiagnostic and therapeutic agents.

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864. Reactive Oxygen Species ActivatableHeterodimeric Prodrug as Tumor-Selective Nanotheranostics.

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863. First report of 68Ga-PRGD2 PET/MRI molecularimaging of vaso-occlusion in a patient with sickle cell disease.

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862. Genetically engineered magnetic nanocages forcancer magneto-catalytic theranostics

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861.Size-Transformable Antigen-Presenting CellMimicking Nanovesicles for Effective Cancer Immunotherapy

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860. Targeted Scavenging of Extracellular ROSRelieves Suppressive Immunogenic Cell Death

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859. New Opportunities in Cancer Immunotherapy andTheranostics.

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858. Cascade Drug Release Strategy for EnhancedAnticancer Therapy

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857. Activating Macrophage-Mediated CancerImmunotherapy by Genetically Edited Nanoparticles

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856. Decoy nanoparticles protect against COVID-19by concurrently adsorbing viruses and inflammatory cytokines

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855. Reducing false negatives in COVID-19 testingby using microneedle-based oropharyngeal swabs

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854. Peptide Receptor Radionuclide Therapy ofLate-stage Neuroendocrine Tumor Patients with Multiple Cycles of177Lu-DOTA-EB-TATE

J Nucl Med. 2020 Aug21:jnumed.120.248658. doi: 10.2967/jnumed.120.248658.

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853. Targeted radionuclide therapy inpatient-derived xenografts using 177Lu-EB-RGD

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852. Recent Advances in Stimuli-ResponsivePlatforms for Cancer Immunotherapy

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851. Cell Death Mediated by Pyroptosis Pathwaywith the Help of Nanotechnology: New Prospects for Cancer Therapy

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850. The critical size of gold nanoparticles forovercoming P-gp mediated multidrug resistance

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849. Endogenous Labile Iron Pool-Mediated FreeRadical Generation for Cancer Chemodynamic Therapy

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848.Designer cell membrane nanovesicles amplifymacrophage immune responses against cancer recurrence and metastasis

Nat Commun, 2020;11(1):4909.

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847. Nanoparticle delivery in vivo: a fresh lookfrom an intravital imaging perspective

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846. Cascade Reactions Catalyzed by Planar MetalOrganic Framework Hybrid Architecture for Combined Cancer Therapy

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845. Multimodal Photoacoustic Imaging-GuidedRegression of Corneal Neovascularization: A Non-Invasive and Safe Strategy

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Chu C, Yu J, RenE, Ou S, Zhang Y, Wu Y, Wu H, Zhang Y, Zhu J, Dai Q, Wang X, Zhao Q, Li W, LiuZ, Chen X, Liu G

 

844. Theranostic multimodal gold nanoclusters

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843. Targeting Neutrophils for Enhanced CancerTheranostics

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842. Advanced biomimetic nanoreactor forspecifically killing tumor cells through multi-enzyme cascade

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Liu W, Wu J, Ji X,Ma Y, Liu L, Zong X, Yang H, Dai J, Chen X, Xue W

 

841. Zwitterionic-to-cationic charge conversionpolyprodrug nanomedicine for enhanced drug delivery

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Wang S, Zhang F, YuG, Wang Z, Jacobson O, Ma Y,Tian R, Deng H, Yang W, Chen ZY, Chen X

 

840. Dancing with reactive oxygen speciesgeneration and elimination in nanotheranostics for disease treatment

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839. Critical reviews of immunotheranostics

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838. Tuning the properties of atomically precisegold nanoclusters for biolabeling and drug delivery

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837. Engineering macrophages for cancerimmunotherapy and drug delivery

Adv Mater,2020;32(40):e2002054.

Xia Y, Rao L, YaoH, Wang Z, Ning P, Chen X

 

836. Controllable Synthesis of VersatileMesoporous Organosilica Nanoparticles as Precision Cancer Theranostics

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835. Insight into the Development of PETRadiopharmaceuticals for Oncology

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834. Ultrasmall Copper-Based Nanoparticles forReactive Oxygen Species Scavenging and Alleviation of Inflammation RelatedDiseases

Nat Commun, 2020;11(1):2788

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833. A single-step multi-level supramolecularsystem for cancer sonotheranostics

Nanoscale Horiz. 2019;4(1):190-195.

Lin H, Li S, WangJ, Chu C, Zhang Y, Pang X, Lv P, Wang X, Zhao Q, Chen J, Chen H, Liu W, Chen X,Liu G

 

832. Quantum Dot-Based Sensitization System forBoosted Photon Absorption and Enhanced Second Near-Infrared Luminescence ofLanthanide[1]DopedNanoparticle

Anal Chem, 2020; 92(8):6094-6102.

Zhang W, Chen T,Su L, Ge X, Chen X, Song J, Yang H

 

831. Early stratification of radiotherapy responseby activatable inflammation magnetic resonance imaging

Nat Commun, 2020;11(1):3032

Zhou Z, Deng H, YangW, Wang Z, Lin L, Munasinghe J, Jacobson O, Liu Y,Tang L, Ni Q, Kang F, Liu Y,Niu G, Bai R, Qian C, Song J, Chen X

 

830. 177Lu-EB-PSMA radioligand therapy withescalating doses in patients with metastatic castration-resistant prostatecancer

J Nucl Med, 2020;61(12):1772-1778.

Zang J, Liu Q, SuiH, Wang R, Jacobson O, Fan X, Zhu Z, Chen X

 

829. Gadolinium-Rose Bengal Coordinated PolymerNanodots for MR/Fluorescence ImageGuided Radiation and Photodynamic Therapy

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828. Biologically Responsive Plasmonic Assembliesfor Second Near-Infrared Window Photoacoustic Imaging-Guided Concurrent Chem[1]Immunotherapy

ACS Nano, 2020; 14(4):3991-4006.

Zhu R, Su L, DaiJ, Li ZW, Bai S, Li Q, Chen X, Song J, Yang H

 

827. [18F]- Alfatide PET imaging of integrin αvβ3for the non-invasive quantification of liver fibrosis

J Hepatol.2020;73(1):161-169.

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826.Yolk-shell nanovesicles endowglutathione-responsive concurrent drug release and T1 MRI activation for cancertheranostics

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825. Stereospecific Interactions between ChiralNanomaterials and Biological Systems

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824. Solvent-assisted self-assembly ofmetal-organic framework-based biocatalyst for cascade reactions-drivenphotodynamic therapy

J Am Chem Soc, 2020; 142(14):6822-6832.

He L, Ni Q, Mu J,Fan W, Liu L, Wang Z, Li L,Tang W, Liu Y, Cheng Y,Tang L, Yang Z, Liu Y, Zou J,Yang W, Jacobson O, Zhang F, Huang P, Chen X

 

823. X-ray-Induced Persistent LuminescencePromotes Ultrasensitive Imaging and Effective Inhibition of Orthotopic HepaticTumors

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822. Targeting Integrins with Radiolabeled RGDAnalogs for Radiotheranostics of Metastatic Radioactive Iodine Non-ResponsiveThyroid Cancer - New Avenues in Personalized Medicine

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821. Photoacoustic Imaging-Trackable MagneticMicroswimmers for Pathogenic Bacterial Infection Treatment

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820. Cell Membrane Mimicking Nanodecoys AgainstInfectious Diseases

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819. Conjugation of a Scintillator Complex andGold Nanorods for Dual-Modal Image-Guided Photothermal and X-RayInducedPhotodynamic Therapy of Tumors

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818.Endoplasmic Reticulum Targeting to AmplifyImmunogenic Cell Death for Cancer Immunotherapy

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817. A Fluorinated-Ionic-Liquid-Based Activatable19F MRI Platform Enables Detection and Imaging of Biological Targets

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816. Lymphangioleiomyomatosis revealed by68Ga-NOTA-Evans Blue PET/CT

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815. Small-sized gadolinium oxide basednanoparticles for high-efficiency theranostics of orthotopic glioblastoma

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814. A phototheranostics strategy to continuouslydeliver singlet oxygen in dark and hypoxic tumor microenvironment

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813. Ultrasound Activated Sensitizers and Applications

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812. Current clinical status and potential ofphotothermal and photodynamic cancer therapy

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811.Burst release of encapsulated annexin A5 intumours boosts cytotoxic T-cell responses by blocking the phagocytosis ofapoptotic cells

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810.Multiplexed NIR-II imaging for lymphnode-invaded cancer detection and full-process light exposure surgery

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809. Oxidative stress-driven DR5 upregulationrestores TRAIL/Apo2L sensitivity induced by iron oxide nanoparticles incolorectal cancer

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808. Cascaded Multiresponsive Self-Assembled 19FMRI Nanoprobes with Redox-Triggered Activation and NIR-Induced Amplification

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807. Combined 68Ga-NOTA-Evans BlueLymphoscintigraphy and 68Ga-NOTA-RM26 PET/CT Evaluation of Sentinel Lymph NodeMetastasis in Breast Cancer Patients

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Zang J, Liu Q, SuiH, Guo H, Peng L, Li F, Lang L, Jacobson O, Mao F, Zhu Z, Chen X

 

806. Smart Nanovesicle Mediated Immunogenic CellDeath Through Tumor Microenvironment Modulation for EffectivePhotodynamic-Immunotherapy

ACS Nano, 2020;14(1):620-631

Yang W, Zhang F,Deng H, Lin L, Wang S, Kang F, Yu G, Lau J,Tian R, Zhang M, Wang Z, He L, Ma Y,Niu G, Hu S, Chen X

 

805. Label-free Visualization of Early CancerHepatic Micrometastasis and Intraoperative Image-guided Surgery byPhotoacoustic Imaging

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804. A bi-adjuvant nanovaccine that potentiatesimmunogenicity of neoantigen for combination immunotherapy of colorectal cancer

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Ni Q, Zhang F, LiuY, Wang Z, Yu G, Liang B, Niu G, Su T, Lu G, Zhu G, Zhang L, Chen X

 

803. Ultrasound Activated Vesicle of Janus Au-MnONanoparticles for Promoted Tumor Penetration and Sono-Chemodynamic Therapy ofOrthotopic Liver Cancer

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Lin X, Liu S,Zhang X, Zhu R, Chen S, Chen X, Song J, Yang H.

 

802. Nanoscintillator-mediated X-ray inducedphotodynamic therapy for deep-seated tumors: from concept to biomedicalapplications

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Sun W, Zhou Z,Pratx G, Chen X, Chen H

 

801. Core–Shell HeterostructuredMagnetic–Plasmonic Nanoassemblies with Highly Retained Magnetic–PlasmonicActivities for Ultrasensitive Bioanalysis in Complex Matrix

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800. Supramolecular Recognition-MediatedLayer-by-Layer Self-Assembled Gold Nanoparticles for Customized Sensitivity inPaper-Based Strip Nanobiosensors

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799. DOTA-Branched Organic Frameworks as Giant andPotent Metal Chelators

J Am Chem Soc. 2020;142(1):198-206.

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798. Tale of Two Magnets: A New Design of MagneticTargeting System

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Zhou Z, Shen Z,Chen X

 

797. Dose Escalation of an Evans Blue ModifiedRadiolabeled Somatostatin Analogue 177Lu-DOTA-EBTATE in the Treatment ofMetastatic Neuroendocrine Tumors

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Liu Q, Cheng Y,Zang J, Sui Hm Wang H, Jacobson O, Zhu Z, Chen X

 

796.Aggregation-InducedEmission Gold Clustoluminogens for Enhanced Low-Dose X-ray-Induced PhotodynamicTherapy

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Angew Chem Int Ed Engl. 2019; 58: 1-8.

 

795.Three-dimensionallabel-free imaging of mammalian yolk sac vascular remodeling with opticalresolution photoacoustic microscopy

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794.AIEgensBarcodes Combined with AIEgens Nanobeads for High-sensitivity MultiplexedDetection

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Theranostics. 2019;9(24):7210-7221.

 

793.Tumourmicroenvironment-responsive semiconducting polymer-based self-assemblynanotheranostics

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Nanoscale Horiz. 2019;4(2):426-433.

 

792.AMetabolically Stable Boron-Derived Tyrosine Serves as a Theranostic Agent forPositron Emission Tomography Guided Boron Neutron Capture Therapy

LiJ, Shi Y, Zhang Z, Liu H, Lang L, Liu T, Chen X, Liu Z.

Bioconjug Chem. 2019;30(11):2870-2878.

 

791.Insitu polymerized hollow mesoporous organosilica biocatalysis nanoreactor forenhancing ROS-mediated anticancer therapy

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790.MagneticManganese Oxide Sweetgum-ball Nanospheres with Large Mesopores Regulate TumorMicroenvironments for Enhanced Tumor Nanotheranostics

FengY, Ding D, Sun W, Qiu Y, Luo L, Shi T, Meng S, Chen X, Chen H.

ACS Appl Mater Interfaces.2019;11(41):37461-37470.

 

789.Enzyme-inducedin vivo assembly of gold nanoparticles for imaging-guided synergisticchemo-photothermal therapy of tumor

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788.Integrinαvβ3-targeted radionuclide therapy combined with immune checkpoint blockadeimmunotherapy synergistically enhances anti-tumor efficacy

ChenH, Zhao L, Fu K, Lin Q, Wen X, Jacobson O, Sun L, Wu H, Zhang X, Guo Z, Lin Q,Chen X.

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787.CancerCell Membrane-Coated Nanoparticles for Personalized Therapy in Patient-DerivedXenograft Models

RaoL, Yu GT, Meng QF, Bu LL, Zan M, Ding J, Li A, Xiao H, Sun ZJ, Liu W, Chen X.

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786.Nanomaterial-BasedBlood-Brain-Barrier (BBB) Crossing Strategies

XieJ, Shen Z, Anraku Y, Kataoka K, Chen X.

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785.Cooperationof endogenous and exogenous reactive oxygen species induced by zinc peroxidenanoparticles to enhance oxidative stress-based cancer therapy

LinLS, Wang JF, Song J, Liu Y, Zhu G, Dai Y, Shen Z, Tian R, Song J, Wang Z, TangW, Yu G, Zhou Z, Yang Z, Huang T, Niu G, Yang HH, Chen ZY, Chen X.

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784.Anisotropicnanomaterials for shape-dependent physicochemical and biomedical applications

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Chem Soc Rev. 2019;48(19):5140-5176.

 

783.Polyphenol-basednanoplatform for MRI/PET dual-modality imaging guided effective combinationchemotherapy

WangJ, Sang W, Yang Z, Shen Z, Wang Z, Jacobson O, Chen Y, Wang Y, Shao M, Niu Dai Y,Chen X.

J Mater Chem B. 2019;7(37):5688-5694.

 

782.PrecisionCancer Theranostic Platform by In Situ Polymerization in PeryleneDiimide-Hybridized Hollow Mesoporous Organosilica Nanoparticles

YangZ, Fan W, Zou J, Tang W, Li L, He L, Shen Z, Wang Z, Jacobson O, Aronova MA,Rong P, Song J, Wang W, Chen X.

J Am Chem Soc.2019;141(37):14687-14698.

 

781.3-18F-fluoropropane-1-thioland 18F-PEG4-1-thiol:Versatile prosthetic groups for radiolabeling maleimidefunctionalized peptides

JacobsonO, Wang Z, Yu G, Ma Y, Chen X, Kiesewetter DO.

Bioorg Med Chem. 2019;115041:115041.

 

780.W-dopedTiO2 nanoparticles with strong absorption in the NIR-II window forphotoacoustic/CT dual-modal imaging and synergistic thermoradiotherapy oftumors

GaoK, Tu W, Yu X, Ahmad F, Zhang X, Wu W, An X, Chen X, Li W.

Theranostics. 2019;9(18):5214-5226.

 

779.Nanotechnologyand nanomaterials based no-wash electrochemical biosensors: from design toapplication

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Nanoscale. 2019; 11: 19105-19118.

 

778.Engineeringof Nanoscale Coordination Polymers with Biomolecules for Advanced Applications

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Coord Chem Rev. 2019;399:213039.

 

777.EnhancedAnti-Tumor Efficacy by Cascade of Reactive Oxygen Species Generation and DrugRelease

WangS, Yu G, Wang Z, Jacobson O, Li L-S, Yang W, Deng H, He Z, Liu Y, Chen Z-Y,Chen X.

Angew Chem Int Ed Engl.2019;58(41):14758-14763.

 

776.Codopingenhanced radioluminescence of nanoscintillators for X-ray-activated synergisticcancer therapy and prognosis using metabolomics

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ACS Nano. 2019;13(9):10419-10433.

 

775.AdvancedNanotechnology Leading the Road of Multimodal Imaging-Guided Precision SurgicalTherapy

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774.InVivo Quantitative Photoacoustic Diagnosis of Gastric and IntestinalDysfunctions with a Broad pH-Responsive Sensor

HuangW, Chen R, Peng Y, Duan F, Huang Y, Guo W, Chen X, Nie L.

ACS Nano. 2019;13(8):9561-9570.

 

773.TumorMicroenvironment-Activated Ultrasensitive Nanoprobes for Specific Detection ofIntratumoral Glutathione by Ratiometric Photoacoustic Imaging

TangL, Yu F, Tang B, Yang Z, Fan W, Zhang M, Wang Z, Jacobson O, Zhou Z, Li L, Liu Y,Kieswetter DO, Tang W, He L, Ma Y, Niu G, Zhang X, Chen X.

ACS Appl Mater Interfaces.2019;11(31):27558-27567.

 

772.HydrogenGas from Inflammation Treatment to Cancer Therapy

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ACS Nano. 2019;13:8505-8511.

 

771.Depth-ResolvedEnhanced Spectral-Domain OCT Imaging of Live Mammalian Embryos Using GoldNanoparticles as Contrast Agent

HuangY, Li M, Huang D, Qiu Q, Lin W, Liu J, Yang W, Yao Y, Yan G, Qu N, Tuchin VV,Fan S, Liu G, Zhao Q, Chen X.

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770.Fluorescenceimaging overcoming the colour barrier

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Nat Photonics. 2019;13:515-516.

 

769.Albuminchaperoned cyanine dye yields super bright NIR-II fluorophore with enhancedpharmacokinetics

TianR, Zeng Q, Zhu S, Lau J, Chandra S, Ertsey R, Hettie K, Teraphongphom T, Hu Z,Niu G, Kiesewetter DO, Sun H, Zhang X, Antaris AL, Brooks BR, Chen X.

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768.X-rayControlled Bilayer Permeability of Bionic Nanocapsules Stabilized by NucleobasePairing Interactions for Pulsatile Drug Delivery

DengH, Lin L, Wang S, Yu G, Zhou Z, Liu Y, Niu G, Song J, Chen X.

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767.ExceedinglySmall Gadolinium Oxide Nanoparticles with Remarkable Relaxivities for MagneticResonance Imaging of Tumors

ShenZ, Fan W, Yang Z, Liu Y, Bregadze VI, Mandal SK, Yung BC, Lin L, Liu T, Tang W,Shan L, Liu Y, Zhu S, Wang S, Yang W, Bryant LH, Nguyen DT, Wu A, Chen X.

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766.Insitu polymerization on nanoscale metal-organic frameworks for enhancedphysiological stability and stimulus-responsive intracellular drug delivery

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765.Synthesisof Copper Peroxide Nanodots for H2O2 Self-Supplying Chemodynamic Therapy

LinLS, Huang T, Song J, Ou XY, Wang Z, Deng H, Tian R, Liu Y, Wang JF, Liu Y, YuG, Zhou Z, Wang S, Niu G, Yang HH, Chen X.

J Am Chem Soc. 2019;141(25):9937-9945.

 

764.Sono-ImmunotherapeuticNanocapturer to Combat Multidrug-Resistant Bacterial Infections

PangX, Liu X, Cheng Y, Zhang C, Ren E, Liu C, Zhang Y, Zhu J, Chen X, Liu G.

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763.AtomicallyPrecise Gold-Levonorgestrel Nanocluster as a Radiosensitizer for EnhancedCancer Therapy

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ACS Nano. 2019;13(7):8320-8328.

 

762.68Ga-NOTA-Aca-BBN(7-14)PET imaging of GRPR in children with optic pathway glioma

ZhangJ, Tian Y, Li D, Niu G, Lang L, Li F, Liu Y, Zhu Z, Chen X.

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761.AVersatile Octapod-Shaped Hollow Porous Manganese(II) Oxide Nanoplatform forReal-Time Visualization of Cargo Delivery

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760.Nanocarbonsfor Biology and Medicine: Sensing, Imaging, and Drug Delivery

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759.Recentadvances in nanomaterial-based synergistic combination cancer immunotherapy

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758.Improvingthe theranostic potential of exendin 4 by reducing the renal radioactivitythrough brush border membrane enzyme-mediated degradation

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757.AnAlbumin-Binding T1-T2 Dual-modal MRI Contrast Agents for Improved Sensitivityand Accuracy in Tumor Imaging

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756.ACatalase-Like Metal-Organic Framework Nanohybrid for O2 -Evolving SynergisticChemoradiotherapy.

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755.Analbumin sandwich enhances in vivo circulation and stability of metabolicallylabile peptides.

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754.TheSignificant Reduction or Complete Eradication of Subcutaneous and MetastaticLesions in a Pheochromocytoma Mouse Model after Immunotherapy UsingMannan-BAM,TLR Ligands, and Anti-CD40.

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753.Recentprogress in nanoscale metal-organic frameworks for drug release and cancertherapy.

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752.Emergingblood-brain-barrier-crossing nanotechnology for brain cancer theranostics.

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751.X-ray-activatednanosystems for theranostic applications

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750.Self-assembledgreen tea polyphenol-based coordination nanomaterials to improve chemotherapyefficacy by inhibition of carbonyl reductase 1

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749.Near-Infrared-IIMolecular Dyes for Cancer Imaging and Surgery

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748.PorphyrinNanocage-Embedded Single Molecular Nanoparticle as Cancer Nanotheranostics

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747.68Ga-NOTA-EvansBlue TOF PET/MR Lymphoscintigraphy Evaluation of the Severity of Lower LimbLymphedema

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746.Ostwaldripening-mediated grafting of metal-organic frameworks on a single colloidalnanocrystal to form uniform and controllable MXF

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745.Ultra-smallquantum dots with broad-spectrum metal doping ability for trimodal molecularimaging

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744.GeneticallyEngineered Cell Membrane Nanovesicles for Oncolytic Adenovirus Delivery: AVersatile Platform for Cancer Virotherapy

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743.SemiconductingPerylene Diimide Nanostructure: Multifunctional Phototheranostic Nanoplatform

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742.GadoliniumMetallofullerene-Based Activatable Contrast Agent for Tumor SignalAmplification and Monitoring of Drug Release

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741.Metal-OrganicFramework Nanoparticle-Based Biomineralization: A New Strategy toward CancerTreatment

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740.Bioengineeringof Metal-organic Frameworks for Nanomedicine

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739.Host–GuestChemistry in Supramolecular Theranostics

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738.ARationally Designed Semiconducting Polymer Brush for NIR-II Imaging-GuidedLight-Triggered Remote Control of CRISPR/Cas9 Genome Editing

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737.Rationaldesign of a super-contrast NIR-II fluorophore affords high-performance NIR-IImolecular imaging guided microsurgery

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736.VesicularAntibodies: A Bioactive Multifunctional Combination Platform for TargetedTherapeutic Delivery and Cancer Immunotherapy

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735.Host−guestcomplexation-mediated codelivery of anticancer drug and photosensitizer forcancer photochemotherapy

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734.Tumor-SpecificDrug Release and Reactive Oxygen Species Generation for CancerChemo/Chemodynamic Combination Therapy

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733.Liposome-basedprobes for molecular imaging: from basic research to the bedside

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732.Wet/Sono-ChemicalSynthesis of Enzymatic Two-Dimensional MnO2 Nanosheets for SynergisticCatalysis-Enhanced Phototheranostics

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731.Monodisperseand uniform mesoporous silicate nanosensitizers achieve low-dose X-ray induceddeep-penetrating photodynamic therapy

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730.FunctionalT Cell Activation by Smart Nanosystems for Effective Cancer Immunotherapy

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729.Core-shellmetal-organic frameworks with fluorescence switch to trigger an enhancedphotodynamic therapy

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728.Pretherapeutic68Ga-PSMA-617 PET May Indicate the Dosimetry of 177Lu-PSMA-617 and177Lu-EB-PSMA-617 in Main Organs and Tumor Lesions

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727.InSitu Dendritic Cell Vaccine for Effective Cancer Immunotherapy

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726.Organosilica-BasedHollow Mesoporous Bilirubin Nanoparticles for Antioxidation-ActivatedSelf-Protection and Tumor-Specific DeoxygenationDriven Synergistic Therapy

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725.CT/MRI-GuidedSynergistic Radiotherapy and X-ray Inducible Photodynamic Therapy UsingTb-Doped Gd-W-Nanoscintillators

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724Structure-Relaxivity Relationships of Magnetic Nanoparticles for MagneticResonance Imaging

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723.Self-AssembledResponsive Bilayered Vesicles with Adjustable Oxidative Stress for EnhancedCancer Imaging and Therapy

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722.Genericsynthesis of small-sized hollow mesoporous organosilica nanoparticles foroxygen-independent X-ray-activated synergistic therapy

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721.Bacteria-ResponsiveNanoliposomes as Smart Sonotheranostics for Multidrug Resistant BacterialInfections

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720.Near-InfraredLight Triggered Sulfur Dioxide Gas Therapy of Cancer

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719.Alogic-gated modular nanovesicle enables programmable drug release for on-demandchemotherapy

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718.Benchto Bedside: Albumin Binders for Improved Cancer

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717.Replyto: Different radionuclides in DOTA-EB-TATE effect different uptake insomatostatin receptor positive HEK293 cells

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716.ComputedTomography and Magnetic Resonance Imaging-Guided Synergistic Radiotherapy andX-ray Inducible Photodynamic Therapy Using TbDoped Gadolinium TungstateNanoscintillators.

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715.InjectableThermosensitive Hydrogel Systems Based on Functional PEG/PCL Block Polymer forLocal Drug Delivery

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714.RatiometricPhotoacoustic Nanoprobe for Bioimaging of Cu2+

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712.Stimuli-responsivenanotheranostics for real-time monitoring drug release by photoacoustic imaging

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711.Advancesin Immunotherapy of Type I Diabetes

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710.Breakingthe depth dependence by nanotechnology-enhanced X-ray-excited deep theranostics

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707.Hybrid Nanomedicine Fabricated fromPhotosensitizerTerminated Metal–Organic Framework Nanoparticles forPhotodynamic Therapy and Hypoxia-Activated Cascade Chemotherapy

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706.Nanoformulated ABT-199 to effectively targetBcl-2 at mitochondrial membrane alleviates airway inflammation by inducingapoptosis

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705.Tumor-SpecificDrug Release and Reactive Oxygen Species Generation for CancerChemo/Chemodynamic Combination Therapy

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704.Acidity/ReducibilityDual-Responsive Hollow Mesoporous Organosilica Nanoplatforms for Tumor-SpecificSelf-Assembly and Synergistic Therapy

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703.TumorMicroenvironment-Responsive Ultrasmall Nanodrug Generators with Enhanced TumorDelivery and Penetration

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702.Fenton-Reaction-AcceleratableMagnetic Nanoparticles for Ferroptosis Therapy of Orthotopic Brain Tumors

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701.Structure-RelaxivityRelationships of Magnetic Nanoparticles for Magnetic Resonance Imaging

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700.PhotoacousticImaging: Contrast Agents and their Biomedical Applications

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699.Reprogramming Tumor-Associated Macrophages byNanoparticle-based Reactive Oxygen Species Photogeneration

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698.High-contentanalysis for mitophagy response to nanoparticles: A potential sensitivebiomarker for nanosafety assessment

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697.Anti-DiabeticEffect of Abextide, a Long-Acting Exendin-4 Analogue in Cynomolgus Monkeys

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696.HierarchicalTumor Microenvironment-Responsive Nanomedicine for Programmed Delivery ofChemotherapeutics

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695.Hybridof Near-Infrared Semiconducting Polymer Brush and pH/GSH-responsivePolyoxometalate Cluster for Enhanced Tumor-Specific Phototheranostics

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694.Adiscrete organoplatinum(II) metallacage as a multimodality theranostic platformfor cancer photochemotherapy

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693.Aptamer-basedtargeted therapy

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692.Combined68Ga-NOTA-PRGD2 and 18F-FDG PET/CT Can Discriminate Uncommon MeningiomaMimicking High-Grade Glioma

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691.BioinspiredArtificial Nanodecoys for Hepatitis B Virus

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690.Automatedradiosynthesis of [18F]FBEM, a sulfhydryl site specific labeling agent forpeptides and proteins

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689.SingleLow-Dose Injection of Evans Blue Modified PSMA-617 Radioligand TherapyEliminates Prostate-Specific Membrane Antigen Positive Tumors

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688.PETImaging of EGFR Expression Using an 18F-labeled RNA Aptamer

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687.First-in-HumanStudy of 177Lu-EB-PSMA-617 in Patients with Metastatic Castration-ResistantProstate Cancer

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686.GadoliniumMetallofullerene-Polypyrrole Nanoparticles for Activatable Dual-Modal ImagingGuided Photothermal Therapy

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685.Near-Infrared-II(NIR-II) Bioimaging via Off-Peak NIR-I Fluorescence Emission

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684.Glutathione-ResponsiveSelf-Assembled Magnetic Gold Nanowreath for Enhanced Tumor Imaging andImaging-Guided Photothermal Therapy

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683.TailoringPlatinum(IV) Amphiphiles for Self-Targeting All-in-One Assemblies as PreciseMultimodal Theranostic Nanomedicine

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682.NovelStructural Modification Based on Evans Blue Dye to Improve Pharmacokinetics ofa Somastostatin-Receptor-Based Theranostic Agent

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681.Controllableself-assembled plasmonic vesicle-based three-dimensional SERS platform forpicomolar detection of hydrophobic contaminants

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680.SupramolecularPolymer-Based Nanomedicine: High Therapeutic Performance and NegligibleLong-Term Immunotoxicity

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679.Gadolinium-encapsulatedgraphene carbon nanotheranostics for imaging-guided photodynamic therapy

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678.Repurposingcyanine NIR-I dyes for near-infrared-II (NIR-II) bioimaging

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677.68Ga-NOTA-RM26PET/CT in the Evaluation of Breast Cancer: A Pilot Prospective Study

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676.RadioligandTherapy of Prostate Cancer with a Long-lasting PSMA Targeting Agent90Y-DOTA-EB-MCG

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675.DottedCore-Shell Nanoparticles for T1-Weighted MRI of Tumors

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674.Chronicneuropathic pain reduces opioid receptor availability with associated anhedoniain rat

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673.Photo-excitableHybrid Nanocomposites for Image-guided Photo/TRAIL Synergistic Cancer Therapy

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672.Enzyme-ResponsiveNanomaterials for Theranostics

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671.SynchronousChemoradiation Nanovesicles by X-ray Triggered Cascade of Drug Release

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670.QuantumDot-Dye Conjugates for Biosensing/Imaging and Therapy

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669.“Three-in-one”Nanohybrids as Synergistic Nanoquenchers to Enhance No-Wash FluorescenceBiosensors for Ratiometric Detection of Cancer Biomarkers

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668.Responseto Single Low-dose 177Lu-DOTA-EB-TATE Treatment in Patients with AdvancedNeuroendocrine Neoplasm: A Prospective Pilot Study

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667.EvansBlue Derivative Functionalized Gold Nanorods for Photothermal Therapy EnhancedTumor Chemotherapy

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666.Safety,Pharmacokinetics and Dosimetry of a Long-Acting Radiolabeled SomatostatinAnalogue 177Lu-DOTA-EB-TATE in Patients with Advanced Metastatic NeuroendocrineTumors.

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665.Non-viraldelivery systems for CRISPR/Cas9-based genome editing: challenges andopportunities

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664.RadioiodinatedSmall Molecule Tyrosine Kinase Inhibitor for HER2 Selective SPECT Imaging

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663.Novelintrapolymerization doped manganese-eumelanin coordination nanocomposites withultrahigh relaxivity and their application in cancer theranostics

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662.Scalable,cGMP-compatible purification of extracellular vesicles carrying bioactive humanheterodimeric IL-15/lactadherin complexes

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661.Ratiometricoptical nanoprobes enable accurate molecular detection and imaging

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660.CooperativeAssembly of Magneto-nanovesicles with Tunable Wall Thickness and Permeabilityfor MRI-guided Drug Delivery

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659.ActivatableSemiconducting Theranostics: Simultaneous Generation and RatiometricPhotoacoustic Imaging of Reactive Oxygen Species In Vivo

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658.18F-AlfatideII PET/CT for Identification of Breast Cancer: A Preliminary Clinical Study

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657.PolymericNanoparticles with Glutathione-Sensitive Heterodimeric Multifunctional Prodrugfor Combined Photodynamic Therapy and Chemotherapy

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656.SmartGold Nanoparticle-Stabilized Ultrasound Microbubbles as Cancer Theranostics

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J Mater Chem B. 2018,6, 3235-3239.

 

655.RadiolabeledAngiogenesis-Targeting Croconaine Nanoparticles for Trimodality Imaging GuidedPhotothermal Therapy of Glioma

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654.SimultaneousFenton-Like Ion Delivery and Glutathione Depletion by MnO2-Based NanoagentEnhances Chemodynamic Therapy

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653.Stimuli-ResponsiveNO Release for On-Demand Gas-Sensitized Synergistic Cancer Therapy

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652.SupramolecularHybrid Material Constructed from Graphene Oxide and Pillar[6]arene-BasedHost–Guest Complex as a Ultrasound and Photoacoustic Signal Nanoamplifier

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651.First-in-humanstudy of PET and optical dual-modality image-guided surgery in glioblastomausing 68Ga-IRDye800CW-BBN

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650.OrganicSemiconducting Photoacoustic Nanodroplets for Laser-Activatable UltrasoundImaging and Combinational Cancer Therapy

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649.Whenradionuclides meet nanoparticles

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648.Apaclitaxel prodrug with bifunctional folate and albumin binding moieties forboth passive and active targeted cancer therapy

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647.Improvinglong-term subcutaneous drug delivery by regulating material-bioenvironmentinteraction

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646.Highlyefficient and stable strain-release radioiodination for thiol chemoselectivebioconjugation

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645.Desminand Vimentin Mediated Hepatic Stellate Cells Targeting Radiotracer99mTc-GlcNAc-PEI for Liver Fibrosis Imaging with SPECT

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644.HypochlorousAcid Promoted Platinum Drug Chemotherapy by Myeloperoxidase EncapsulatedTherapeutic Metal Phenolic Nanoparticles

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643.BiodegradableHollow Mesoporous Organosilica Nanotheranostics for Mild Hyperthermia-InducedBubble-Enhanced Oxygen-Sensitized Radiotherapy

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642.Preclinicalevaluation of an 18F-trifluoroborate methionine derivative for glioma imaging

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641.ArtificialMolecular Machines in Nanotheranostics

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640.Radiotheranosticsin Cancer Diagnosis and Management

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639.68Ga-BBN-RGDPET/CT for GRPR and Integrin αvβ3 Imaging in Patients with Breast Cancer

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638.PolyrotaxaneBased Supramolecular Theranostics

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637.Yolk-ShellNanostructures: Design, Synthesis, and Biomedical Applications

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636.EmergingStrategies of Cancer Therapy Based on Ferroptosis

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635.Polysaccharide-basedControlled Release Systems for Therapeutics Delivery and Tissue Engineering:from Bench to Bedside

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634.EvansBlue Attachment Enhances Somatostatin Receptor Subtype-2 Imaging andRadiotherapy

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633.GeneticallyEngineered Liposome-like Nanovesicles as Active Targeted Transport Platform

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632.MetalIon Assisted Interface Re-engineering of Ferritin Protein Nanocage for EnhancedBiofunctions and Cancer Therapy

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631.PositronEmission Tomography Using a GRPR Antagonist 68Ga-RM26 in Healthy Volunteers andProstate Cancer Patients

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630.Insitu shRNA synthesis on drug-loaded DNA-polylactide nanoparticles for thetreatment of multidrug resistant breast cancer

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629.Afacile supramolecular approach to nucleic acid-driven activatablenanotheranostics that overcome drawbacks of photodynamic therapy

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628.PETof Prostate Cancer with Ga-68 Labeled GRPR Agonist BBN7-14 and Antagonist RM26

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627.ToxicReactive Oxygen Species Enhanced Synergistic Combination Therapy bySelf-Assembled Metal-phenolic Network Nanoparticles

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626.Ceriananocrystals decorated mesoporous silica nanoparticle based ROS-scavengingtissue adhesive for highly efficient regenerative woundhealing

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625.Functional ferritin nanoparticles forbiomedical applications

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624.Supramolecular Nanomedicine Constructed fromCucurbit[8]uril-Based Amphiphilic Brush Copolymer for Cancer Therapy

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623.Reprogrammableultra-fast shape-transformation of macroporous composite hydrogel sheets

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J Mater Chem B Mater Biol Med. 2017;5(16):2883-2887.

 

622.Designand development of multifunctional polyphosphoester-based nanoparticles forultrahigh paclitaxel dual loading

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621.Albumin/VaccineNanocomplexes That Assemble In Vivo for Combination Cancer Immunotherapy

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620.AntitumorActivity of a Unique Polymer That Incorporates a Fluorescent Self-AssembledMetallacycle

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619.InhibitingMetastasis and Preventing Tumor Relapse by Triggering Host Immunity withTumor-Targeted Photodynamic Therapy Using Photosensitizer-Loaded FunctionalNanographenes

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618.2DGold Nanorings Enhance Tumor Uptake and Suppress Nanoparticle-MononuclearPhagocyte System Interaction

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617.Ceriananocrystals decorated mesoporous silica nanoparticle based ROS-scavengingtissue adhesive for highly efficient regenerative wound healing

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616.IntertwiningDNA-RNA nanocapsules loaded with tumor neoantigens as synergistic nanovaccinesfor personalized cancer immunotherapy

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615.Microneedle-arraypatches loaded with dual mineralized protein/peptide particles for type 2diabetes therapy

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614.EngineeredZn(II)-Dipicolylamine-Gold Nanorod Provides Effective Prostate Cancer Treatmentby Combining siRNA Delivery and Photothermal Therapy

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613.Blackhollow silicon oxide nanoparticles as highly efficient photothermal agents inthe second near-infrared window for in vivo cancer therapy

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612.MultifunctionalTheranostic Nanoparticles Based on Exceedingly Small Magnetic Iron OxideNanoparticles for T1-Weighted Magnetic Resonance Imaging and Chemotherapy

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611.TransformativeNanomedicine of an Amphiphilic Camptothecin Prodrug for Long Circulation andHigh Tumor Uptake in Cancer Therapy

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610.Nanotechnologyfor multimodal synergistic cancer therapy

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609.Chemotherapeuticdrug-photothermal agent co-self-assembling nanoparticles for near-infraredfluorescence and photoacoustic dual-modal imaging-guided chemo-photothermalsynergistic therapy

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608.Emergingadvances in nanotheranostics with intelligent bioresponsive systems

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607.ImprovedTumor Targeting and Longer Retention Time of NIR Fluorescent Probes UsingBioorthogonal Chemistry

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606.Peptidesand Peptide Conjugates in Medicine

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605.T1-T2Dual-Modal Magnetic Resonance Imaging: From Molecular Basis to Contrast Agents

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604.ProteinNanocages that Penetrate Airway Mucus and Tumor Tissue

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603.RationalDesign of Branched Nanoporous Gold Nanoshells with Enhanced Physico-opticalProperties for Optical Imaging and Cancer Therapy

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602.Core-SatellitePolydopamine-Gadolinium Metallofullerene Nanotheranostics for MultimodalImaging Guided Synergistic Cancer Therapy

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601.Double-LayeredPlasmonic-Magnetic Vesicles by Self-Assembly of Janus Amphiphilic Au–Fe3O4Nanoparticles

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600.Nanotechnology-Enhanced No-Wash Biosensors for In Vitro Diagnostics of Cancer

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599.Ultrasound-MediatedDiagnosis and Therapy

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598.EnhancedAfterglow Performance of Persistent Luminescence Implants for EfficientRepeatable Photodynamic Therapy

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597.MolecularImaging of Acute Cardiac Transplant Rejection: Animal Experiments and Prospects

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596.MultifunctionalMolecular Beacon Micells for Intracellular mRNA Imaging and Synergistic Therapyin Multidrug-Resistant Cancer Cells

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595.PET-guidedevaluation and optimization of internalized antibody-drug conjugates targetingerythropoietin producing hepatoma A2 receptor

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594.Quantificationof Tumor Vascular Permeability and Blood Volume by Positron Emission Tomography

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593.Long-actingrelease formulation of exendin-4 based on biomimetic mineralization for type 2diabetes therapy

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592.Nanoparticledesign strategies for enhanced anticancer therapy by exploiting tumourmicroenvironment

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591.Self-Assemblyof Semiconducting-Plasmonic Gold Nanoparticles with Enhanced Optical Propertyfor Photoacoustic Imaging and Photothermal Therapy

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590.BiocompatibleD–A Semiconducting Polymer Nanoparticle with Light-Harvesting Unit for HighlyEffective Photoacoustic Imaging Guided Photothermal Therapy

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589.Ultra-smallSemimetal Nanoparticles of Bismuth for Dual-Modal CT/Photoacoustic Imaging andSynergistic Thermoradiotherapy

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588.ActivatableSinglet Oxygen Generation from Lipid Hydroperoxide Nanoparticles for CancerTherapy

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587.Impactof Semiconducting Perylene Diimide Nanoparticle Size on Lymph Node Mapping andCancer Imaging

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586.Tumormicroenvironment-triggered supramolecular system as in situ nanotheranosticgenerator for enhanced cancer phototherapy

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585.RethinkingCancer Nanotheranostics

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584.Yolk-ShellNanostructure: An Ideal Architecture to Achieve Harmonious Integration ofMagnetic-Plasmonic Hybrid Theranostic Platform

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583.Croconainenanoparticles with enhanced tumor accumulation for multimodality cancertheranostics

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582.Reprogrammableultra-fast shape-transformation of macroporous composited hydrogel sheets

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581.RecentAdvances in High-Performance fluorescent and bioluminescent RNA Imaging Probes

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580.CurrentDetection Technologies of Circulating Tumor Cells

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579.EfficientNanovaccine Delivery in Cancer Immunotherapy

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578.Artificiallocal magnetic field inhomogeneity enhances T2 relaxivity

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577.Tri-Stimuli-ResponsiveBiodegradable Theranostics for Mild Hyperthermia Enhanced Chemotherapy

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576.Cancer-Associated,Stimuli-Driven,Turn on Theranostics for Multimodal Imaging Guided Therapy

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575.DiverseApplications of Nanomedicine

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574.AnUltrasensitive Biosensing Platform Employing Acetylcholinesterase and GoldNanoparticles

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573.Combinatoryscreening of DNA aptamers for molecular imaging of HER2 in cancer

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572.DegradableHollow Mesoporous Silicon/Carbon Nanoparticles for Photoacoustic Imaging-GuidedHighly Effective Chemo-Thermal Tumor Therapy in Vitro and in Vivo

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571.Developmentof sialic acid-coated nanoparticles for targeting cancer and efficient evasionof the immune system

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570.TAT-modifiedgold nanoparticle carrier with enhanced anticancer activity and size effect onovercoming multidrug resistance

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569.RatiometricPhotoacoustic Molecular Imaging for Methylmercury Detection in Living Subjects

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568.Engineeringphototheranostic nanoscale metal-organic frameworks for multi-modalimaging-guided cancer therapy

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567.HighlySpecific C-C Bond Cleavage Induced FRET Fluorescence for in vivo BiologicalNitric Oxide Imaging

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566.Glucose-ResponsiveSequential Generation of H2O2 and NO for Synergistic Cancer Starving-Like/GasTherapy

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565.ImprovedTumor Uptake by Optimizing Liposome Based RES Blockade Strategy

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564.AmphiphilicPolymer-Guided Plasmonic Assemblies and Their Biomedical Applications

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Bioconjugate Chem. 2017; 28(1): 105–114.

 

563.IronOxide Nanoparticles-based Contrast Agents for Magnetic Resonance Imaging

ShenZ, Wu A, Chen X.

Mol Pharm. 2017;14(5):1352-1364.

 

562.MappingSentinel Lymph Node Metastasis by Dual-probe Optical Imaging

YangX, Wang Z, Zhang F, Zhu G, Song J, Teng G, Niu G, Chen X.

Theranostics. 2017; 7(1):153-163.

 

561.Combinationof nitric oxide and drug delivery systems: tools for overcoming drug resistancein chemotherapy

KimJ, Yung BC, Kim WJ, Chen X.

J Control Release. DOI:10.1016/j.jconrel.2016.12.026.

 

560.Novelmolecular “add-on” based on Evans Blue confers superior pharmacokinetics andtransforms drugs to theranostic agents

ChenH, Jacobson O, Niu G, Weiss ID, Kiesewetter DO, Liu Y, Ma Y, Wu H, Chen X.

J Nucl Med. 2017;58(4):590-597.

 

559.ConvertingRed Blood Cells to Efficient Microreactors for Blood Detoxification

XuC, Yang X, Fu X, Niu G, Hu S, Ali I, Chen X.

Adv Mater. 2016 Nov 28. doi: 10.1002/adma.201603673.

 

558.Clinicaltranslation of a dual integrin αvβ3 and GRPR targeting PET radiotracer68Ga-NOTA-BBNRGD

ZhangJ, Niu G, Lang L, Li F, Fan X, Yan X, Yao S, Yan W, Huo L, Chen L, Li Z, Zhu Z,Chen X.

J Nucl Med. 2017;58(2):228-234.(Cover feature)

 

557. A tetraphenylethene-based highly emissivemetallacage as a component of theranostic supramolecular nanoparticles

Yu G, Cook TR, Li Y, Yan X, Wu D, Shao L Shen J, Tang G, Huang F, Chen X, StangPJ.

PNAS. 2016;113(48):13720-13725.

 

556.Enzyme-freecolorimetric determination of EV71 virus using a 3D-MnO2-PEG nanoflower and4-MBA-MA-AgNPs

Chu C, Ge S, Zhang J, Lin H, Liu G, Chen X.

Nanoscale. 2016;8(36):16168-16171.

 

555.Synergisticthermoradiotherapy based on PEGylated Cu3BiS3 ternary semiconductor nanorodswith strong absorption in the second near-infrared window

Li A, Li X, Yu X, Li W, Zhao R, An X, Cui D, Chen X, Li W.

Biomaterials. 2016;112:164-175.

 

554.HierarchicalAssembly of Bioactive Amphiphilic Molecule Pairs into Supramolecular NanofibrilSelf-Supportive Scaffolds for Stem Cell Differentiation

Wang Z, Zhang F, Wang Z, Fu X, Jin A, Yung BC, Fan J, Yang X, Niu G, Chen X.

J Am Chem Soc. 2016;138(45):15027-15034.

 

553.ReactiveOxygen Species Generating Systems Meeting Challenges of Photodynamic CancerTherapy

Zhou Z, Song J, Nie L, Chen X.

Chem Soc Rev. 2016;45(23):6597-6626.

 

552.Albumin-BindingEvans Blue Derivatives for Diagnostic Imaging and Production of Long-ActingTherapeutics

Jacobson O, Kiesewetter DO, Chen X.

Bioconjug Chem. 2016;27(10):2239–2247.

 

551.NewGeneration of Gold Nanoshell-Coated Esophageal Stent: Preparation andBiomedical Applications

Song J, Hu H, Wu K, Chen X.

ACS Appl Mater Interfaces. 2016;8(41):27523–27529.

 

550.DCE-MRI-DerivedParameters in Evaluating Abraxane-Induced Early Vascular Response and theEffectiveness of Its Synergistic Interaction with Cisplatin

Sun X, Yang L, Yan X, Sun Y, Zhao D, Ji Y, Wang K, Chen X, Shen B.

PLoS One.2016;11(9):e0162601.

 

549.Pillar[5]arene-basedamphiphilic supramolecular brush copolymers: fabrication, controllableself-assembly and application in self-imaging targeted drug delivery

Yu G, Zhao R, Wu D, Zhang F, Shao L, Zhou J, Yang J, Tang G, Chen X, Huang F.

Polymer Chem.2016;7:6178-6188.

 

548.Magneto-PlasmonicJanus Vesicles for Magnetic Field-Enhanced Photoacoustic and Magnetic ResonanceImaging of Tumor

Liu Y, Yang X, Huang Z, Huang P, Zhang Y, Deng L, Wang Z, Zhou Z, Liu Y, Kalish H,Khachab NM, Chen X, Nie Z.

Angew Chem Int Ed Engl.2016;55(49):15297-15300.

 

547.AHighly Efficient Approach to Copper-Mediated Radioiodination Approach usingUsing Aryl Boronic Acids

Zhang P, Zhuang R, Guo Z, Su X, Chen X, Zhang X.

Chem Eur J. 2016;22(47):16783-16786.

 

546.CCCCC pentadentate chelates with planar Möbius aromaticity and uniqueproperties.

Zhu C, Yang C, Wang Y, Lin G, Yang Y, Wang X, Zhu J, Chen X, Lu X, Liu G, Xia H.

Sci Adv. 2016 Aug 26;2(8):e1601031.

 

545.Overcomingthe Achilles’ heel of photodynamic therapy

Fan W, Huang P, Chen X.

Chem Soc Rev.2016;45(23):6488-6519.

 

544.Sizedependent kinetics of gold nanorods in EPR mediated tumor delivery

Tong X, Wang Z, Sun X, Song J, Jacobson O, Niu G, Kiesewetter DO, Chen X.

Theranostics. 2016; 6(12):2039-2051.

 

543.RecentAdvances in Photoacoustic Imaging for Deep-Tissue Biomedical Applications

Wang S, Lin J, Wang T, Chen X, Huang P.

Theranostics.2016;6(13):2394-2413.

 

542.Light-ResponsiveBiodegradable Nanomedicine Overcomes Multidrug Resistance via NO-EnhancedChemosensitization

Fan J, He Q, Liu Y, Zhang F, Yang X, Wang Z, Lu N, Fan W, Lin L, Niu G, He N, SongJ, Chen X.

ACS Appl Mater Interfaces. 2016 Jun8;8(22):13804-11.

 

541.Peptide-basedimaging agents for cancer detection

Sun X, LiY, Liu T, Li Z, Zhang X, Chen X.

Adv Drug Deliv Rev.2016 Jun 18.pii: S0169-409X(16)30191-0.

 

540.Temporal-spatiallytransformed synthesis and formation mechanism of gold bellflowers

 

Lin J, Zhang MG, Tang Y, Wen B, Hu H, Song J, Liu Y, Huang P, Chen X.

Nanoscale.2016 Apr14;8(14):7430-4. (Front Cover).

 

539.EGFR-targetedtherapy results in dramatic early lung tumor regression accompanied by imagingresponse and immune infiltration in EGFR mutant transgenic mouse models

Venugopalan A, Lee MJ, Niu G, Medina-Echeverz J, Tomita Y, Lizak MJ, Cultraro CM, SimpsonRM, Chen X, Trepel JB, Guha U.

Oncotarget.2016;7(34):54137-54156.

 

538.Efficientproduction and enhanced tumor delivery of engineered extracellular vesicles

Watson DC, Bayik D, Srivatsan A, Bergamaschi C, Valentin A, Niu G, Bear J, MonningerM, Sun M, Morales-Kastresana A, Jones JC, Felber BK, Chen X, Gursel I, PavlakisGN.

Biomaterials. 2016 Jul 6;105:195-205.

 

537.GoldNanoparticle Coated Carbon Nanotube Ring with Enhanced Raman Scattering andPhotothermal Conversion Property for Theranostic Applications

Song J, Wang F, Yang X, Huang P, Nie L, Lin L, Niu G, Chen J, Chen X.

J Am Chem Soc.2016 Jun8;138(22):7005-15.

 

536.Graphene-BasedNanomaterials in Bioimaging

Huang P, Lin J, Chen X.

Adv Drug Deliv Rev. 2016;105(PtB):242-254.

 

535.Self-assemblymechanisms of nanofibers from peptide amphiphiles in solution and on substratesurfaces

LiaoHS, Lin J, Liu Y, Gao Y, Horkay F, Huang P, Jin A, Chen X.

Nanoscale.2016 Aug4;8(31):14814-20.

 

534.MonitoringTumor Hypoxia Using 18F-FMISO PET and Pharmacokinetics Modeling afterPhotodynamic Therapy

TongX, Srivatsan A, Jacobson O, Wang Y, Wang Z, Yang X, Niu G, Kiesewetter DO,Zheng H, Chen X.

Sci Rep. 2016 Aug 22;6:31551.

 

533.HierarchicalTargeting Strategy for Enhanced Tumor Tissue Accumulation/Retention andCellular Internalization

WangS, Huang P, Chen X.

Adv Mater.2016Sep;28(34):7340-64.

 

532.APhotothermally Responsive Nanoprobe for Bioimaging Based on the EdmanDegradation

LiuY, Wang Z, Zhang H, Lang L, Ma Y, He Q, Lu N, Huang P, Liu Y, Gao S, Ma Q,Kiesewetter DO, Chen X

Nanoscale.2016;8(20):10553-7.

 

531.UltrasensitiveFluorescence Immunoassay for the Detection of Ochratoxin A UsingCatalase-Mediated Fluorescence Quenching of CdTe QDs

HuangX, Zhan S, Xu H, Meng X, Xiong Y, Chen X.

Nanoscale.2016 Apr28;8(17):9390-7.

 

530.Preparationof Plasmonic Vesicles from Amphiphilic Gold Nanocrystals Grafted with PolymerBrushes

SongJ, Huang P, Chen X.

Nat Protoc.2016;11(11):2287-2299.

 

529.PotentialApplications of Using 68Ga-Evans Blue PET/CT in the Evaluation of LymphaticDisorder

WangZ, Huang P, Jacobson O, Wang Z, Liu Y, Lin L, Lin J, Lu N, Zhang H, Tian R, NiuG, Liu G, Chen X.

ACS Nano. 2016;10(3):3453-60.

 

527.ProgrammedSpecific Targeting in Nanomedicine

WangS, Huang P, Chen X.

ACS Nano.2016;10(3):2991-4.

 

526.MultimodalImaging Guided Cancer Phototherapy by Versatile Biomimetic Theranostics with UVand γ Irradiation Protection

HuangP, Wang M, Hu H, Yang X, Wen B, Wang Z, Song J, Zhang G, Niu G, Wang T, HuangP, Chen X.

Adv Mater. 2016 May;28(17):3273-9.

 

525.Photoacousticmolecular imaging: from multiscale biomedical applications towards early-stagetheranostics

LiuY, Nie L, Chen X.

Trends Biotechnol. 2016;34:420-33.

 

524.DNA-inorganichybrid nanovaccine for cancer immunotherapy

ZhuG, Liu Y, Yang X, Kim Y-H, Zhang H, Jia R, Liao H-S, Jin A, Lin J, Aronova M, LeapmanR, Nie Z, Niu G, Chen X.

Nanoscale.2016;8:6684-6692.

 

523.Simplebioconjugate chemistry serves great clinical advances: Albumin as a versatileplatform for diagnosis and precision therapy

LiuZ, Chen X.

Chem Soc Rev.2016;45(5):1432-56.

 

522.Ultrahigh19F Loaded Cu1.75S Nanoprobes for Simultaneous 19F Magnetic Resonance Imagingand Photothermal Therapy

ChenH, Song M, Tang J, Hu G, Xu S, Guo Z, Li N, Cui J, Zhang X, Chen X, Wang L.

ACS Nano.2016;10(1):1355-62.

 

521.Artificialcells: from basic science to applications

XuC, Hu S, Chen X.

Mater Today.2016;19(9):516-532.

 

520.[18F]NOTA-T140Peptide for Noninvasive Visualization of CXCR4 Expression

YanX, Niu G, Wang Z, Yang X, Kiesewetter DO, Jacobson O, Shen B, Chen X.

Mol Imaging Biol. 2016;18(1):135-42.

 

519.Glucagon-likepeptide-1 receptor PET/CT with 68Ga-NOTA-exendin 4 for the localization ofinsulinoma: a prospective cohort study

LuoY, Pan Q, Yao S, Zhang J, Yu M, Wu W, Xue H, Kiesewetter DO, Zhu Z, Li F, Zhao Y,Chen X.

J Nucl Med. 2016 May;57(5):715-20.

 

518.68Ga-NOTA-exendin-4PET/CT in localization of an occult insulinoma and appearance of coexistingesophageal carcinoma

LuoY, Li N, Kiesewetter DO, Chen X, Li F.

Clin Nucl Med.2016;41:341-343.

 

517.AStable Evans Blue Derived Exendin-4 peptide for Type 2 Diabetes Treatment

LiuY, Wang G, Zhang H, Ma Y, Lang L, Jacobson O, Kiesewetter DO, Zhu L, Gao S, MaQ, Chen X.

Bioconjug Chem. 2016;27(1):54-8.

 

516.Dual-enhancedphotothermal conversion property of reduced graphene oxide-coated goldsuperparticles for light-triggered acoustic and thermal theranostics

LinL, Yang X, Niu G, Song J, Yang H-H, Chen X.

Nanoscale. 2016; 8: 2116-2122.

 

515.Chemicalconjugation of Evans blue derivative: a strategy to develop long-actingtherapeutics through albumin binding

ChenH, Wang G, Lang L, Jacobson O, Kiesewetter DO, Liu Y, Ma Y, Zhang X, Wu H, ZhuL, Niu G, Chen X.

Theranostics.2016;6(2):243-253.

 

514.Effectof Surface Properties on Liposomal siRNA Delivery

XiaY, Tian J, Chen X.

Biomaterials.2016;79:56-68.

 

513.BioconjugatedManganese Dioxide Nanoparticles Enhance Chemotherapy Response by PrimingTumor-Associated Macrophages toward M1-like Phenotype and Attenuating TumorHypoxia

SongM, Liu T, Shi C, Zhang X, Chen X.

ACS Nano. 2016;10(1):633-47.

 

512.Invivo Covalent Cross-linking of Photon-converted Rare-earth Nanostructures forTumor Localization and Theranostics

AiX, Ho CJH, Aw J, Attia ABE, Wang X, Wang Y, Chen H, Gao M, Chen X, Yeow EKL,Liu G, Olivio M, Xing B.

Nat Comm.2016;7:10432.

 

511.MolecularImaging Guided Delivery of RNAi Therapeutics for Cancer

WangJ, Mi P, Lin G,   Wang Y, Liu G, Chen X

Adv Drug Deliv Rev.2016 Sep1;104:44-60.

 

510.RGDPET: From Lesion Detection to Therapy Response Monitoring

NiuG, Chen X.

J Nucl Med.2016Apr;57(4):501-2.

 

509.Ananoparticulate pre-chemosensitizer for efficacious chemotherapy of multidrugresistant breast cancer

GuoS, Lv L, ShenY, Hu Z, He Q, Chen X.

Sci Rep. 2016;6:21459.

 

508.Invivo MR and Fluorescence Dual-modality Imaging of AtherosclerosisCharacteristics in Mice Using Profilin-1 Targeted Magnetic Nanoparticles

WangY, Su T, Chen J, Ma S, Zhang X, Li X, Chen Y, Cao L, Yang B, Liu G, Cao J, ChenX, Chen Y, Cao F.

Theranostics.2016;6(2):272-286.

 

507.68Ga-NOTA-Aca-BBN(7-14)PET/CT in Healthy Volunteers and Glioma Patients

ZhangJ, Li D, Lang L, Zhu Z, Wang L, Wu P, Niu G, Li F, Chen X

 

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