▍ Selected Publications

1246. Liu J, He L, Chen X, Xu R, Liang X, Li G,  Zeng Q, Gong Y, Jiao W, Liu Y, Xu J, Zhang X, Li W, Gan R, Dai J, Chen X, Chen W.

A trajectory-modulating endoscope-actuated microneedle-based“bullet”for precise and penetrating peptic ulcer treatment

Device, DOI: 10.1016/j.device.2026.101144

 

1245. Peng Y, Shi C, Cao Y, Shi L, Fang F, Chen X.

Breaking the Hypoxia Barrier: Supramolecular Nanoassemblies Empower Photodynamic Therapy of Tumors.

Angew Chem Int Ed Engl. 2026 May 1:e25238.

 

1244. Wu W, Zhang C, Yang Y, Gao L, Zeng Y, Luo Z, Dong X, Zhang X, Chen X.

A Bone Marrow-Targeted Nanomodulator as a Histone Lactylation Inhibitor for Reversing Immune Tolerance in Multiple Myeloma

ACS Nano 2026 Apr 21; doi: 10.1021/acsnano.5c21396.

 

1243. Zhu J, Zhou T, Tang X, Gao Y, Teng Q, Zhang Y, Lv Z, Chen X, Zou J, Shi H.

Injectable Cu2+ loaded rhein hydrogel for cross-amplifying osteosarcoma apoptosis and cuproptosis epitranscriptomically.

Biomaterials. 2026 Mar 28;332:124170. doi: 10.1016/j.biomaterials.2026.124170.

 

1242. Dai W, Wang X, Wang R, Wei Q, Qin C, Liu J, Zhou X, Jia F, Ji J, Ding J, Chen X, Jin Q.

Selective Induction of Cancer Cell Pyroptosis by Erbium Nanotuner Enhances Potent Anti-Cancer Immunity.

Adv Mater. 2026 Mar 30:e22094. doi: 10.1002/adma.202522094. 

 

1241. Xu H, Wu J, Qin J, Li Z, Guo J, Li Z, Wu Y, Tang K, Chen X, Liu Y, Zhu J.

Dual-Interface Hierarchical Assembly of Asymmetric ICG-Lipid Conjugates Enables Finite J-type Aggregation and Two-Stage NIR-II Fluorescence Enhancement.

Nano Lett. 2026 Mar 30. doi: 10.1021/acs.nanolett.5c05913. 

 

1240. Zang QX, Chen WT, Shen YY, Wang ZY, Li K, Zhao X, Sang Y, Chen X, Zang SQ.

Highly Active Cu14 Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy.

Adv Sci (Weinh). 2026 Mar 26:e17021.

 

1239. Qiu Z, Zheng X, Pan S, Zhong Y, Chen X, Wen X, Chen X, Li S, Cheng H, Chen X.

Stearic acid-modified PSMA-targeting peptide-drug conjugate for long-acting prostate cancer therapy.

Chem Sci. 2026 Mar 5. doi: 10.1039/d5sc08259e.

 

1238. Yang B, Li B, Zhu Y, Zhao M, Cheng Y, Zhao X, En-Jie DT, Wang Y, Zhang M, Tang X, Jin S, Sun Y, Zhang X, Xue B, Yan J, Wu G, Lin Z, Luo M, Yu H, Zhang L, Chen X, Ni Q.

Rational design of rigid mRNA folding architecture to enhance intracellular processing and protein production.

Nat Nanotechnol. 2026 Mar 2. doi: 10.1038/s41565-025-02114-9. 

 

1237. Li X, Zhang R, Tan J, Xiong Y, Lu G, Li K, He T, Li P, Huang W, Chen X.

Triplet π-Conjugated Oligomer Nanoparticles with High Intersystem Crossing Efficiency for 808 nm Laser-Activated Photodynamic Therapy.

ACS Nano. 2026 Mar 2. doi: 10.1021/acsnano.5c18799.

 

1236. He X, Li Y, Wang X, He Y, Li Y, Yang W, Li W, Wang K, Lin J, Chen X.

Natural killer cell-inspired dendritic mesoporous rare-earth nanoparticles potentiate X-ray-triggered reactive oxygen generation for low-dose radiotherapy-radiodynamic therapy.

Bioact Mater. 2026 Feb 17;61:464-481. 

 

1235. Zhen W, Han WK, Zhao T, Reszegi RR, Wei Z, Gu ZG, Zhang J, Chen X.

MSA-2 Loaded Three-Dimensional Metal Covalent Organic Framework for Synergistic Radiosensitization and Innate Immune Activation.

J Am Chem Soc. 2026 Feb 22. doi: 10.1021/jacs.5c19020.

 

 

1234. Chen L, Xu Y, Hu X, Pan Y, She P, Chen X, Peng Q, Li Q, Rao L.

In situ generation of dendritic cell vaccines in 3D printing scaffolds for cancer post-surgical therapy.

Natl Sci Rev. 2026 Jan 20;13(5):nwag037.

 

1233. Liu R, Li S, Gao X, Zou Q, Shu G, Zhang C, Pan J, Chen X, Sun SK.

Hypersensitive detection of single millimeter vascular emboli from adhesive in vivo.Nat Commun. 2026 Feb 10. doi: 10.1038/s41467-026-68534-w. 

1232. Chen G, Li X, Huang Y, Zheng C, Fang H, Zhang Q, Liu K, Wu K, Zhu Q, Guo C, Zhu H, Dai R, He Y, Zhu Q, Zhou W, Yang Y, Li Z, Qu K, Li B, Xiao S, Tian S, Xing B, Chen X, Wang AZ, Xiong Y, Min Y.

X-ray activated platinum complex induces DNA damage and enhances cancer immunotherapy through abscopal effect.

Nat Biomed Eng. 2026 Feb 9. doi: 10.1038/s41551-026-01612-y. 

 

1231. Li S, Wu H, Deng J, Sun Q, Zhang Y, Zhang C, Pan J, Liu D, Zhang X, Zou Q, Chen X, Sun SK.

Gram-Scale Synthesis of Hafnium-Rich Carbon Dots for Preclinical Computed Tomography Imaging Across Various Systems.

Adv Sci (Weinh). 2026 Jan 31:e17986. 

 

1230. Li B, Wang J, Peng Y, Liu C, Ming Y, Yang B, He D, Lai W, Guo L, Zhao M, Chen X.

BODIPY-Doped Nanocarrier Engineering (BONE) Improves Bone Marrow mRNA Delivery by NIR-II Bioimaging Guided Screening.

J Am Chem Soc. 2026 Jan 30. doi: 10.1021/jacs.5c14271. 

 

1229. Feng Z, Chu L, Li Q, Zhou J, Wu P, Zhang X, Pan Y, Zou J, Chen Q, Xu Z, Yan L, Huang Y, Li X, Wang Z, Chen X.

Engineered VPg saRNA achieves cap-independent, low-immunogenic and precise encoding of therapeutic proteins in vivo.

Nat Commun. 2026 Jan 27. doi: 10.1038/s41467-026-68364-w. 

 

1228. Feng Z, Pan Y, Zhou J, Chu L, Li Q, Zhang X, Wu P, Xu Z, Huang Y, Zou J, Li X, Chen X, Wang Z.

Tmem110 regulates the conformation of TRPML1 to maintain endolysosomal homeostasis and prevent mitochondrial DNA leakage and pathological self-DNA processing.

Nat Commun. 2026 Jan 15. doi: 10.1038/s41467-026-68382-8. 

 

1227. Cao Y, Wang J, Wang H, Sun X, Fang F, Li S, Liu J, Shi C, Qi P, Zou J, Chen X, Cai K.

Targeting Peptostreptococcus anaerobius with an Iron-Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer.

Adv Sci (Weinh). 2026 Jan 12:e16272. 

 

1226. Zhang L, Wang M, Wang B, Zhao J, Sun B, Yu Y, Han K, Wang X, Zhang J, Wei M, Deng J, Li J, Li M, Ke Y, Jiang H, Yan H, Chen X, Peng X, Bai Y, Wang W.

Side-Chain Engineering Guides the Design of β-Sheet Inhibitor to Anchor Protein-Protein Interaction Interfaces.

Angew Chem Int Ed Engl. 2026 Jan 7:e21473. 

1225. Chen X, Zhou D, Wang J, Liu H, Zhang H, Geng Z, Wang G, Shen H, Zhang Y, Li Z, Wang D, Ren X, Wang X, Xu K, He C, Bai L, Wei Y, Chen X, Su J.

Viral glycoprotein-mimicking peptide-functionalized micelles promote drug delivery to diseased chondrocytes for osteoarthritis alleviation.

Nat Nanotechnol. 2025 Dec 29. doi: 10.1038/s41565-025-02082-0.

 

1224. Cui T, Chen S, Liu S, Niu X, Wang J, Ao R, Cai H, Huang H, Yu M, Peng S, Chen X, Lin L.

A biohybrid chiral hydrogel enhances preclinical postoperative glioblastoma therapy by multi-pronged inhibition of tumour stemness.

Nat Nanotechnol. 2025 Dec 26. doi: 10.1038/s41565-025-02064-2.

 

1223. Sang Y, Zhang Y, Chen SY, Zang QX, Wang ZY, Chen X, Zang SQ.

recision-Architected Drug-Stabilized Cu5 Clusters Mediate Multimodal Therapeutic Intervention in Colitis.

ACS Nano. 2025 Dec 22. doi: 10.1021/acsnano.5c12046.

 

1222. Zhang X, Ning S, Fang F, Zhou C, Yang Z, Cao L, Wang K, Feng Z, Li B, Luo D, Xu X, Liu Z, Chen X, Yu Z.

Leveraging Cisplatin-Derived Prodrugs as Helper Lipids in LNPs to Boost the Efficacy of Cancer Chemoimmunotherapy.

ACS Nano. 2025 Dec 22. doi: 10.1021/acsnano.5c18243.

 

1221. Cui X, Chen X.

Editorial: Novel ultrasound-based strategies for precision therapeutics and visualization.

Adv Drug Deliv Rev. 2025 Dec 16:115763. 

 

1220. Mu J, Song J, Chen X.

Innovations in Radiotherapeutic Materials for Personalized Oncology.

ACS Appl Mater Interfaces. 2025 Dec 17;17(50):67399-67400. 

 

1219. Shu G, Lang M, Deng J, Zhang Y, Cheng R, Pan J, Wang X, Liu D, Zhang C, Chen X, Sun SK.

An Ultralong-Circulating Tantalum-Based Computed Tomography Contrast Agent for Vascular Imaging in Large Animals.

ACS Nano. 2025 Dec 17. doi: 10.1021/acsnano.5c13773.

 

1218. Wei Z, Zhen W, Chen X, Zhang J.

Tumor targeted radionuclide-nanomedicine for clinical translation: From carrier innovation to precision therapy.

J Control Release. 2025 Dec 12;390:114543. 

 

1217. Chen X.

AT-17 redefines local anesthetics by targeting mitochondrial apoptosis.

Acta Pharm Sin B. 2025 Nov;15(11):6087-6088. 

 

1216. Yang X, Wang Y, Zhou J, Li S, Ye J, Sun Y, He M, Fan K, Chen Z, Tian F, Zhao B, Zhang J, Xie J, Xiao Z, Chen X, Ju S.

Engineering a spatiotemporal macrophage circuit via STING phase separation to override immune suppression in pancreatic cancer.

Proc Natl Acad Sci U S A. 2025 Nov 25;122(47):e2504718122. 

 

1215. Yu X, Qi S, Zhang W, Li H, Cao F, Wang Y, Peng K, Lin X, Chen X, Yu G.

Lipid Nanoparticle Chaperone with Redox-Adaptive Intracellular Microenvironment Modulation Potentiates the Potency of mRNA Vaccines.

J Am Chem Soc. 2025 Nov 20. doi: 10.1021/jacs.5c10972. 

 

1214. Zhang C, Zhao WH, Zuo D, Zhou T, Hou W, Wang L, Shi S, Yang Y, Liu Y, Sun SK, Ren L, Ye Z, Liu D, Li D, Chen X, Hao J.

AI-Guided SERS Defines a Pan-Cancer Diagnostic Biomarker.

Adv Sci (Weinh). 2025 Nov 16:e16268.

 

1213. Chen X, Lu L, Liu Y, Liang Z, Li J, Shao Z, Tang Y, Zou J, Li S, Chen X.

CD169+ Macrophage-Targeted Immunomodulator to Restore Phagocytic Function and Enhance Antigen Presentation for Lymphatic Metastasis Eradication.

Adv Sci (Weinh). 2025 Nov 16:e14386.

 

1212. Zhang M, Xu J, Yang Z, Ding L, Han H, Ma M, Ee PLR, Yu G, Tang W, Chen X.

Glycolysis-inhibiting tumor cell-derived microparticles to enhance immunogenic cell death for synergistic cancer immunotherapy.

Biomaterials. 2025 Nov 2;328:123832. 

 

1211. Zhang M, Wang Y, Tang X, Zhang W, Mao Z, Yu Y, Yang X, Yu G, Chen X.

Mineralized Supramolecular Microspheres with Immunoregulating Functions for Transarterial Chemoembolization Immunotherapy of Hepatocellular Carcinoma.

Small Methods. 2025 Oct 24:e00857. 

 

1210. Tang Y, Luo Z, Ma Z, Han L, Zhou Y, Liang T, Yang K, Zhao L, Chen X, Zhang P.

Condensate nanovaccine adjuvants augment CD8+ T-Cell-dependent antitumor immunity through mtDNA leakage-triggered cGAS-STING axis activation.

Signal Transduct Target Ther. 2025 Oct 21;10(1):349. 

 

1209. Yang L, Li J, Ling S, Du F, Liao W, Li R, Li Y, Zhou Z, Jin Z, Chen X, Zhao Q.

NIR-II Dual-Modal Photoacoustic and OCT/OCTA Contrast Mechanisms Imaging Microenvironment Responses for Precision-Guiding Tumor Photothermal Theranostics.

Small Methods. 2025 Oct 13:e00955. 

 

1208. Qi L, Zhang W, Shi C, Feng C, Liu Z, Li Z, Fang F, Chen X.

Dual Targeting of m7G tRNA Modification and Histone Acetylation using Carrier-Free Nano-Epidrugs to Evoke Osteosarcoma Chemosensitization.

Adv Mater. 2025 Oct 10:e05951. 

 

1207. Programmable Bimetallic MOF Nanozyme Composite with Microenvironment-Adaptive Cascade Catalysis for Wearable Glucose Biosensing and Accelerated Diabetic Wound Healing.

Yu K, Li X, Zhan S, Chai H, Cao X, Cao F, Guan J, Xu Q, Gao X, Qu L, Zhang X, Zhang G, Chen X.

Anal Chem. 2025 Oct 7;97(39):21668-21678. 

 

1206. Shen L, Yu J, Chen W, Bi Y, Yang Z, Lu C, Jiang C, Yang Y, Chen M, Zou J, Lv L, Chen X, Ji J.

PPP1R3B Suppresses Atherosclerosis by Promoting the M2 Polarization of Macrophages Through Glycogen Metabolic Reprogramming.

Adv Sci (Weinh). 2025 Nov;12(41):e06345. 

 

1205. Li J, Wen X, Reszegi RR, Kamalrhaj H, Parak WJ, Chen X, Zhang J.

Advances in radiopharmaceuticals for cancer radiotheranostics: CCK2R targeting as a paradigm for translational innovation.

Cancer Commun (Lond). 2025 Nov;45(11):1431-1455. 

 

1204. Chen X.

From Quantum Dots to Cancer Nanotheranostics.

Nano Lett. 2025 Sep 9. doi: 10.1021/acs.nanolett.5c03619. 

 

1203. Suo M, Wang Z, Zhang S, Tang W, Liang D, Chen X, Ning S.

Bionic nanomedicines for microwave-triggered cuproptosis to enhance cancer immunotherapy.

Nanoscale Horiz. 2025 Sep 9. doi: 10.1039/d5nh00425j.

 

1202. Wu Q, Yao X, Duan X, Chen X, Zhang J.

Nanomedicine Reimagined: Translational Strategies for Precision Tumor Theranostics.

Adv Mater. 2025 Sep 6:e10293.

 

1201. Zhang Y, Zhang Y, Liang R, Zou J, Pei R, Chen X.

Targeted ROS Scavenging for Disease Therapies Using Nanomaterials

Adv Mater. 2025 Aug 22:e04435.

 

1200. Liu Y, Zhang X, Chen X, Zhang F.

Proteolysis-targeting chimera (PROTAC) nanomedicines toward cancer treatment: From synthesis to therapeutic delivery.

Biomaterials. 2025 Aug 8;325:123621. 

 

1199. Wang J, Wang F, Jiang Y, Bai L, Chen X, Su J.

Organoid-driven nanomedicine platform development.

Biomaterials. 2025 Aug 7;325:123611. 

 

1198. Feng Y, Tai W, Huang P, Qi S, Yu X, Li M, Li M, Zhang M, Cao F, Gao X, Yang K, Bai B, Lei J, Cheng M, Li Y, Cheng G, Chen X, Yu G.

Albumin-recruiting lipid nanoparticle potentiates the safety and efficacy of mRNA vaccines by avoiding liver accumulation.

Nat Mater. 2025 Aug 1. doi: 10.1038/s41563-025-02284-w. 

 

1197. Deng C, Yu L, Zhao X, Chen Y, Mei J, Wei J, Chen X, Lei G, Zeng C.

Genetically engineered chondrocyte-mimetic nanoplatform attenuates osteoarthritis by blocking IL-1β and restoring sirtuin-3.

Sci Adv. 2025 Jul 25;11(30):eadv4238. 

 

1196. Fan Q, Wang M, Lin J, Huang Y, Yang J, Zhu J, Ren B, Sun L, Li Z, Liu A, Xiong W, Wei Z, Huang L, Yan C, Wen G, Chen Z, Chen X, Shen Z.

A Mesoporous Calcium Peroxide Nanocuboid with High Tumor Accumulation Across Biological Barriers for High Efficacy Tumor Therapy.

Adv Sci (Weinh). 2025 Jul 20:e10778. doi: 10.1002/advs.202510778. 

 

1195. Zhao C, Pan Y, Cao L, Tang Y, Chen X, Zhao X, Rao L.

Metal-Phenolic Outer Membrane Vesicles for Cancer Radioimmunotherapy.

J Am Chem Soc. 2025 Jul 30;147(30):26195-26207.

 

1194. Shen L, Jiang C, Song J, Bi Y, Chen W, Lu C, Chen M, Lv L, Yu R, Zou J, Zhao Z, Chen X, Ji J.

Microenvironment responsive nanoplatform for targeted removal of cholesterol and reshaping inflammatory microenvironment in atherosclerotic plaques.

J Control Release. 2025 Sep 10;385:114000. 

 

1193. Bai Q, Shao X, Xia Q, Yang S, Gao Y, Sun K, Li J, Wang X, Tian Z, Chen X, Zhao J, Diao J, Chen Q.

Optogenetic engineering of lipid droplet spatial organization for tumor suppression.

Trends Biotechnol. 2025 Jul 1:S0167-7799(25)00217-3. 

 

1192. Zeng Q, Gong Y, Jiao W, Xu J, Chen X, Xu R, Liu Y, Liang X, Li G, Liu J, He L, Li W, Zhang X, Chen X, Chen W.

Smart ultra-long-lasting sequentially triggerable and artfully implantable nozzle system for on-demand drug delivery for chronotherapy.

Sci Adv. 2025 Jun 27;11(26):eadv8734. 

 

1191. Mi Z, Chen J, Zhang Z, Liu J, Lei Y, Tan H, Li W, Chen X, Rong P.

Synthetic biology-driven induction of mature TLS formation enhances antitumor immunity in colorectal cancer.

Sci Transl Med. 2025 Jun 18;17(803):eado8395. 

 

1190. You Q, Wu G, Li H, Liu J, Cao F, Ding L, Liang F, Zhou B, Ma L, Zhu L, Wang C, Yang Y, Chen X.

A nanovaccine targeting cancer stem cells and bulk cancer cells for postoperative cancer immunotherapy.

Nat Nanotechnol. 2025 Jun 16. doi: 10.1038/s41565-025-01952-x. 

 

1189. Liu J, Chen X.

Biomineral tablets for long-acting IL-2 immunotherapy.

Nat Cancer. 2025 Jun 10. doi: 10.1038/s43018-025-00951-0. 

 

1188. Zhang X, Song Z, Zhang X, Zou J, Yu G, Chen X, Wang S.

Unconventional PROTACs for Targeted Protein Degradation in Cancer Therapy.

Angew Chem Int Ed Engl. 2025 Jul 28;64(31):e202507702.

 

1187. Wei Y, Geng X, You Q, Zhang Y, Cao F, Narayanan G, Nguyen T, Chen X, Zhang J, Ye L.

Human induced pluripotent stem cell derived nanovesicles for cardiomyocyte protection and proliferation.

Bioact Mater. 2025 May 2;50:585-602. 

 

1186. Wang R, Xi T, Li K, Wang C, Gao X, Yang H, Zou J, Chen X, Sun L.

Self-Assembled Fluorescent Peptide Nanoprobes for Disease Diagnosis.

Small Methods. 2025 Jun 1:e2500518.

 

1185. Chen X, Lu L, Liang Z, Yu B, Shao Z, Li J, Cen Y, Liu Y, Li S, Chen X.

Self-Promoting Targeted Delivery of Epigenetic Immunostimulants to Activate Breast Cancer Immunity via HDACs Downregulation and PD-L1 Upregulation.

Angew Chem Int Ed Engl. 2025 May 27:e202502120. 

 

1184. Zhao X, Han J, Liu J, Wang ZY, Chen X, Zang SQ.

Au6Cu2 Clusters with High Electron Affinity and Oxygen-Mimetic Properties for Hypoxic Tumor Radiosensitization.

Angew Chem Int Ed Engl. 2025 May 19:e202504524. 

 

1183. Fang G, Liu D, Bai Q, Shao X, Liu Z, Yao Q, Yuan Y, Zeng K, Chen X, Chen X, Chen Q.

An Environmentally Responsive Molecular Engineering Framework for Subcellular Drug Translocalization.

Adv Mater. 2025 May 13:e2503220.

 

1182. Li Z, Ren G, Wang X, Li X, Ding L, Zhu J, Zhang Y, Zhang C, Zou J, Chen X.

Tumor microenvironment responsive nano-PROTAC for BRD4 degradation enhanced cancer photo-immunotherapy.

Biomaterials. 2025 May 7;322:123387. 

 

1181. Yu B, Zhang W, Shao Z, Chen X, Cen Y, Liu Y, Chen Y, Li X, Liang Z, Li S, Chen X.

Self-promoted tumor-targeting nanomedicine activates STING-driven antitumor immunity via photodynamic DNA damage and PARP inhibition.

Chem Sci. 2025 May 1. doi: 10.1039/d5sc01953b. 

 

1180. Wang R, Zhu J, Zhou J, Li J, Wang M, Wu Y, Zhao D, Chen X, Chen X, Wang Y, Zou J.

Bioinspired Claw-Engaged Adhesive Microparticles Armed with γGC Alleviate Ulcerative Colitis via Targeted Suppression of Macrophage Ferroptosis.

Adv Sci (Weinh). 2025 Apr 29:e2503903. doi: 10.1002/advs.202503903. 

 

1179. Huang P, Liu Y, Zhao C, Wang C, Wang L, Luo M, Wang W, Shan W, Liu X, Li B, Wang Z, Deng H, Chen X.

Permanent Efferocytosis Prevention by Terminating MerTK Recycle on Tumor-Associated Macrophages for Cancer Immunotherapy.

J Am Chem Soc. 2025 Apr 28. doi: 10.1021/jacs.5c05640. 

 

 

1178. Hou G, Cheng X, Jiang Y, Yang Y, Chen B, Huang Z, Li Z, Zhou A, Chen X, Zheng R, Zhao H, Zhang J, Wang X.

Comparison of Al18F-NOTA-FAPI-74 and 18F-FDG PET/CT in the Evaluation and Staging of Hepatobiliary Malignancies: A Single-center Prospective Study.

Clin Nucl Med. 2025 Apr 24. doi: 10.1097/RLU.0000000000005889. 

 

 

1177. Zhu Y, Wang D, Du C, Wu T, Wei P, Zheng H, Li G, Zheng S, Su L, Yan L, Hu Y, Wang H, Lin L, Ding C, Chen X.

Ruthenium Single-Atom Nanozyme Driven Sonosensitizer with Oxygen Vacancies Enhances Electron-Hole Separation Efficacy and Remodels Tumor Microenvironment for Sonodynamic-Amplified Ferroptosis.

Adv Sci (Weinh). 2025 Apr 25:e2416997. doi: 10.1002/advs.202416997.

 

1176. Zhang D, Chen Q, Zhang J, Xing X, Zhou Y, Ou X, Dai S, Chen Q, Liu X, Chen X, Zeng Y.

Amplifying X-ray-Induced Charge Transfer Facilitates Direct Sensitization of Photosensitizers in Radiotherapy.

ACS Nano. 2025 Apr 25. doi: 10.1021/acsnano.5c01506. 

 

1175. Zhen W, Zhao T, Chen X, Zhang J.

Unlocking the Potential of Disulfidptosis: Nanotechnology-Driven Strategies for Advanced Cancer Therapy.

Small. 2025 Apr 24:e2500880. doi: 10.1002/smll.202500880. 

 

1174. Zhou P, Huang R, Cheng Y, Yang Y, Qian D, Ming X, Wang AZ, Chen X, Min Y.

Nanotherapeutic Wee1 Inhibition Sensitizes Tumor Ferroptosis to Promote Cancer Immunotherapy and Abscopal Effect.

ACS Nano. 2025 Apr 22. doi: 10.1021/acsnano.4c13218. 

 

1173. Hou L, Wang Y, Fu H, Chen L, Yu C, Chen X, Zhang J.

PSMA-targeted radioligand therapy with [177Lu]Lu-LNC1011 for metastatic castration-resistant prostate cancer: a pilot study.

Eur J Nucl Med Mol Imaging. 2025 Apr 10. doi: 10.1007/s00259-025-07245-8. 

 

1172. Liu P, Ding H, Jia S, Pang Y, Li C, Zhao T, Skudder-Hill L, Wang J, Chen H, Zhao X, Chen X, Zhang J.

Molecular Imaging of B7-H3-Targeting Bispecific T Cell-Engaging Antibody MGD009 in Glioblastoma Models.

ACS Appl Mater Interfaces. 2025 Apr 4. doi: 10.1021/acsami.5c01451. 

 

1171. Guo W, Wen X, Chen Y, Zhao T, Liu J, Tao Y, Fu H, Wang H, Xu W, Pang Y, Zhao L, Huang J, Xu P, Guo Z, Miao W, Zhang J, Chen X, Chen H.

Safety, dosimetry, and efficacy of an optimized long-acting somatostatin analog for peptide receptor radionuclide therapy in metastatic neuroendocrine tumors: From preclinical testing to first-in-human study.

Acta Pharm Sin B. 2025 Feb;15(2):707-721.

 

1170. Pei P, Chen Y, Chen X, Zhang F, Liu X, Wang JW.

Optothermal-Stimulated Persistent Luminescence Imaging and Therapy (OSPLIT).

Adv Mater. 2025 Mar 31:e2500769. 

 

1169. Chen J, Wei Z, Shan Y, Chen S, Wu Z, Liu S, Zhang J, Chen X, Liu B.

Bottom-Up Selective Growth of Ultralong Organic Phosphorescence Nanocrystals with Optimized Crystal Forms for In Vivo Optical Imaging.

Adv Mater. 2025 Mar 24:e2418795. 

 

1168. Yang H, Wang J, Wen X, Guo H, Jakobsson V, Zhao T, Zeng F, Shen H, Zhang H, Liu X, Qin Y, Li X, Xiong H, Zhou Z, Zhang J, Chen X.

Dansylated Amino Acid-Modified Long-Acting PSMA Derivatives 68Ga/177Lu-LNC1011 as Prostate Cancer Theranostics.

J Nucl Med. 2025 Mar 20:jnumed.124.268959. doi: 10.2967/jnumed.124.268959.

 

1167. Zhu K, Wang J, Wang Z, Chen Q, Song J, Chen X.

Ultrasound-Activated Theranostic Materials and their Bioapplications.

Angew Chem Int Ed Engl. 2025 Mar 17:e202422278.

 

1166. Fu H, Huang J, Zhao L, Chen Y, Xu W, Cai J, Yu L, Pang Y, Guo W, Su B, Sun L, Wu H, Zhang J, Chen X, Chen H.

177Lu-LNC1004 Radioligand Therapy in Patients with End-stage Metastatic Cancers: A Single-Center, Single-Arm, Phase II Study.

Clin Cancer Res. 2025 Mar 14:OF1-OF12.

 

1165. Wang R, Wang J, Xiang J, Sui H, Li L, Jia C, Peng X, Chen X, Zhu Z, Zhang J.

Comparison of [68Ga]Ga-Fibroblast Activation Protein Inhibitor-04 and [18F]FDG PET Imaging for Solitary Fibrous Tumor and Preliminary Application of FAP-Targeted Radiopharmaceutical Therapy.

J Nucl Med. 2025 Mar 6:jnumed.124.268258. doi: 10.2967/jnumed.124.268258.

 

1164. Zhang Y, Wu X, Wang K, Tang Y, Lu X, Sun F, Tang H, Chen X, Ning S.

Simultaneous Reversal of T Lymphocytes and Cancer Cells Metabolism Via a Biomimetic Heavy-Atom-Free Photosensitizers-Based Combination Therapies to Boost Cancer Photoimmunotherapy.

Adv Sci (Weinh). 2025 Mar 5:e2416143.

 

1163. Zhang X, Zhang X, Fan Q, Li J, Jia S, Chen X, Wang S.

Self-Accelerated Nanoregulators for Positive Feedback Ferroptosis-Immunotherapy.

Small. 2025 Mar 3:e2408156.

 

1162. Gu W, Tian Q, Xie T, Chen X.

Genetically reprogrammed exosomes for cancer immunotherapy.

Mol Ther. 2025 Mar 5;33(3):837-839.

 

1161. Wen X, Zhao T, Yang H, Shi M, Wee XJ, Fu J, Lin M, Zhang Z, Zou M, Green D, Wu X, Chen X, Zhang J.

Development of [225Ac]Ac‑LNC1011 for targeted alpha-radionuclide therapy of prostate cancer.

Eur J Nucl Med Mol Imaging. 2025 Feb 24. doi: 10.1007/s00259-025-07155-9.

 

1160. Ning S, Shangguan P, Zhu X, Ou X, Wang K, Suo M, Shen H, Lu X, Wei X, Zhang T, Chen X, Tang BZ.

Pyridinium Rotor Strategy toward a Robust Photothermal Agent for STING Activation and Multimodal Image-Guided Immunotherapy for Triple-Negative Breast Cancer.

J Am Chem Soc. 2025 Mar 5;147(9):7433-7444.

 

1159. Dong J, Ding J, Luo S, Li R, Wang Y, Xiao B, Pei Y, Chen X, Sun W, Pei Z.

Remodeling tumor microenvironment using prodrug nMOFs for synergistic cancer therapy.

J Nanobiotechnology. 2025 Feb 19;23(1):123.

 

1158. Hu C, Tan H, Zhang Y, Cao G, Wu C, Lin P, Qiu S, Mo F, Wang E, Li S, Yuan T, Li Z, Fu W, Cheng D, Lai H, Chen X, Wang L.

Fibroblast Activation Protein Acts as a Biomarker for Monitoring ECM Remodeling During Aortic Aneurysm via 68Ga-FAPI-04 PET Imaging

Adv Sci (Weinh). 2025 Feb 14:e2411152.

 

1157. Caldas C, Chen X, Ding L, Kather JN, Scaltriti M.

Breaking frontiers with multidisciplinary cancer research

Nat Cancer. 2025 Jan;6(1):13-15.

 

1156. Wang R, Li Y, Li Z, Wang J, Li L, Xiang J, Jia C, Peng X, Wang Y, Ma W, Wang L, Jia W, Chen X, Li D, Zhu Z, Zhang J.

Gastrin-Releasing Peptide Receptor Targeting PET/CT With 68Ga-NOTA-RM26 in the Assessment of Glioma and Combined Multiregional Biopsies

Clin Nucl Med. 2025 Jan 14. doi: 10.1097/RLU.0000000000005651.

 

1155. Xiong H, Wang R, Zhang H, Zhang Q, Qin Y, Du C, Zhang X, Ye J, Shi C, Shen H, Zhu Z, Zhou Z, Chen X, Zhang J.

Preclinical and First-in-Human Study of a Compact Radionuclide Labeled Self-Assembly Nanomedicine for Chemo-Radio-Theranostics of Cancer

ACS Nano. 2025 Jan 13. doi: 10.1021/acsnano.4c18489.

 

1154. Gao Y, Bai Q, Ren Y, Shao X, Zhang M, Wu L, Lewis S, James T, Chen X, Chen Q.

A Small-Molecule Drug for the Self-Checking of Mitophagy

Angew Chem Int Ed Engl. 2025 Jan 12:e202421269.

 

1153. Chen J, Zhou Y, Pang Y, Fu K, Luo Q, Sun L, Wu H, Lin Q, Su G, Chen X, Zhao L, Chen H.

FAP-targeted radioligand therapy with 68Ga/177Lu-DOTA-2P(FAPI)2 enhance immunogenicity and synergize with PD-L1 inhibitors for improved antitumor efficacy

J Immunother Cancer. 2025 Jan 11;13(1):e010212.

1152. Peng S, Chen Z, Wang J, Yu M, Niu X, Cui T, Ao R, Cai H, Huang H, Lin L, Chen X, Yang H.

One-Pot Synthesis of Oxygen Vacancy-Rich Amorphous/Crystalline Heterophase CaWO4 Nanoparticles for Enhanced Radiodynamic-Immunotherapy

Adv Sci (Weinh). 2024 Dec 27:e2409551.

 

1151. Zhang M, Wang Y, Li B, Yang B, Zhao M, Li B, Liu J, Hu Y, Wu Z, Ong Y, Han X, Ding L, Zhu K, Li J, Luo M, Chen S, Peng L, Zhang L, Chen X, Ni Q.

STING-Activating Polymers Boost Lymphatic Delivery of mRNA Vaccine to Potentiate Cancer Immunotherapy

Adv Mater. 2024 Dec 23:e2412654.

 

1150. Li H, Zeng J, You Q, Zhang M, Shi Y, Yang X, Gu W, Liu Y, Hu N, Wang Y, Chen X, Mu J.

X-ray-activated nanoscintillators integrated with tumor-associated neutrophils polarization for improved radiotherapy in metastatic colorectal cancer

Biomaterials. 2025 May;316:123031.

 

1149. Hou DY, You Q, Zhang P, Li XP, Wu JC, Wang Y, You HH, Lv MY, Wu G, Liu X, Guo P, Cheng DB, Chen X, Xu W.

Cascade-Activatable Nanoprodrug System Augments Sonochemotherapy of Bladder Cancer

ACS Nano. 2024 Dec 17. doi: 10.1021/acsnano.4c12967.

 

1148. Wang R, Li H, He S, Feng Y, Liu C, Hao K, Zhou D, Chen X, Tian H.

Spatiotemporal Nano-Regulator Unleashes Anti-Tumor Immunity by Overcoming Dendritic Cell Tolerance and T Cell Exhaustion in Tumor-Draining Lymph Nodes

Adv Mater. 2024 Dec 11:e2412141.

 

1147. He L, Yang Y, Cao X, Zhu X, Liu N, Chen X, Zhang J, Zhang W.

[18F]AlF-NOTA-pentixather PET/CT of CXCR4 in patients with suspected primary hyperaldosteronism

Theranostics. 2024 Oct 28;14(19):7281-7291.

 

1146. Shen L, Chen M, Su Y, Bi Y, Shu G, Chen W, Lu C, Zhao Z, Lv L, Zou J, Chen X, Ji J.

NIR-II Imaging for Tracking the Spatiotemporal Immune Microenvironment in Atherosclerotic Plaques

ACS Nano. 2024 Dec 4. doi: 10.1021/acsnano.4c10739.

 

1145. Zhang K, Feng W, Mou Z, Zhang L, Ma M, Zhao Z, Liu X, Chen X, Li Z.

Late-stage (radio)fluorination of alkyl phosphonates via electrophilic activation

Nat Commun. 2024 Nov 28;15(1):10338.

 

1144. Gao H, Chen J, Yang Z, Zhu Z, He L, Zhang W, Chen X, Zhang J.

Comparative Study of [18F]AlF-LNC1007, [18F]FDG, and [18F]AlF-NOTA-FAPI-04 PET/CT in Breast Cancer Diagnosis: A Methodological Exploration and Analytical Insight

ACS Appl Mater Interfaces. 2024 Nov 28. doi: 10.1021/acsami.4c17912.

 

1143. Huang Y, Zhang C, Zhang L, Chen X, Fan W.

Chemical Synthesis and Multihybridization of Small-Sized Hollow Mesoporous Organosilica Nanoparticles Toward Advanced Theranostics

Acc Chem Res. 2024 Nov 22. doi: 10.1021/acs.accounts.4c00502.

 

1142. Zhen W, Chen X.

Inflammasome-Activating Nanovaccine for Cancer Immunotherapy.

Cancer Res. 2024 Nov 15;84(22):3709-3711.

 

1141. Ge D, Ma S, Sun T, Li Y, Wei J, Wang C, Chen X, Liao Y.

Pulmonary delivery of dual-targeted nanoparticles improves tumor accumulation and cancer cell targeting by restricting macrophage interception in orthotopic lung tumors.

Biomaterials. 2024 Nov 8;315:122955

 

1140. Sun Y, Qu F, Geng R, Xiao W, Bi D, Xiong B, Liu Y, Zhu J, Chen X.

Electrostatic Assembly of Gold Nanoclusters in Reverse Emulsion Enabling Nanoassemblies with Tunable Structure and Size for Enhanced NIR-II Fluorescence Imaging

ACS Nano. 2024;18(46):32126-32144.

 

1139. Dong L, Zhu Y, Zhang H, Gao L, Zhang Z, Xu X, Ying L, Zhang L, Li Y, Yun Z, Zhu D, Han C, Xu T, Yang H, Ju S, Chen X, Zhang H, Xie J.

Open-Source Throttling of CD8+ T Cells in Brain with Low-Intensity Focused Ultrasound-Guided Sequential Delivery of CXCL10, IL-2, and aPD-L1 for Glioblastoma Immunotherapy

Adv Mater. 2024 Nov;36(44):e2407235.

 

1138. Zhou QQ, Guo J, Wang Z, Li J, Chen M, Xu Q, Zhu L, Xu Q, Wang Q, Pan H, Pan J, Zhu Y, Song M, Liu X, Wang J, Zhang Z, Zhang L, Wang Y, Cai H, Chen X, Lu G.

Rapid visualization of PD-L1 expression level in glioblastoma immune microenvironment via machine learning cascade-based Raman histopathology

J Adv Res. 2024 Nov;65:257-271.

 

1137. Qiao K, Pan Y, Zhang S, Shi G, Yang J, Zhang Z, Wang K, Chen X, Ning S.

Cold Exposure Therapy Sensitizes Nanodrug-Mediated Radioimmunotherapy of Breast Cancer

ACS Nano. 2024 Oct 29;18(43):29689-29703.

 

1136. Wang R, Kang W, Liu Z, Zheng Y, Sui H, Li L, Wang J, Xiang J, Peng X, Chen X, Zhu Z, Zhang J.

Head-to-Head Comparison of [68Ga]Ga-NOTA-RM26 and [18F]FDG PET/CT in Patients with Gastrointestinal Stromal Tumors: A Prospective Study

J Nucl Med. 2024 Oct 24:jnumed.124.267810. doi: 10.2967/jnumed.124.267810.

 

1135. Wang H, You Q, Kang B, Jing H, Shi Z, Krizkova S, Heger Z, Adam V, Chen X, Li N.

Pulling the Rug Out from Under: Biomechanical Microenvironment Remodeling for Induction of Hepatic Stellate Cell Quiescence

Adv Mater. 2024;36:e2406590.

 

1134. Chen Y, Zheng S, Zang J, Shao Z, Tu D, Liu Q, Chen X, Miao W, Zhang J.

[68Ga]Ga-LNC1007 versus 2-[18F]FDG in the evaluation of patients with metastatic differentiated thyroid cancer: a head-to-head comparative study

Eur J Nucl Med Mol Imaging. 2024 Oct 15. doi: 10.1007/s00259-024-06930-4.

 

1133. Dong K, Lin W, Zhu T, Sun S, Zhang C, Xu C, Cao F, Chen X.

NIR-Actuated Botanicals/Nanozymes Nanofibrous Membranes for Antibiotic-Free Triple-Synergistic Therapy Against Polymicrobial Wound Infections

Adv Healthc Mater. 2024 Oct 14:e2401657.

 

1132. Rao L, Yuan Y, Shen X, Yu G, Chen X

Designing nanotheranostics with machine learning

Nat Nanotechnol, 2024 Oct 3. doi: 10.1038/s41565-024-01753-8.

 

1131. Guo Y, Li Y, Zhang M, Ma R, Wang Y, Weng X, Zhang J, Zhang Z, Chen X, Yang W.

Polymeric nanocarrier via metabolism regulation mediates immunogenic cell death with spatiotemporal orchestration for cancer immunotherapy

Nat Commun. 2024 Oct 4;15(1):8586.

 

1130. Nie S, Yang B, Ma R, Zha L, Qin Y, Ou L, Chen X, Li L.

Synthetic nanomaterials for spleen-specific mRNA delivery

Biomaterials. 2024 Sep 28;314:122859.

 

1129. Wang L, Dong C, Zhang W, Ma X, Rou W, Yang K, Cui T, Qi S, Yang L, Xie J, Yu G, Wang L, Chen X, Liu Z.

Developing an enhanced chimeric permuted intron-exon system for circular RNA therapeutics

Theranostics. 2024 Sep 9;14(15):5869-5882.

 

1128. Zhao Y, Cheng J, Li Z, Wang J, Chen X.

Nanozymes in Biomedical Applications: Innovations Originated From Metal-Organic Frameworks

Adv Healthc Mater. 2024 Sep 25:e2402066.

 

1127. Xie S, Shi W, Duan S, Huang X, Liu A, Hou X, Lin X, Zhong D, Sun S, Ding Z, Yang X, Chen X, Lu X.

A nanobody-guided multifunctional T cell engager promotes strong anti-tumor responses via synergistic immuno-photothermal effects

J Nanobiotechnology. 2024 Sep 14;22(1):561.

 

1126. Dong L, Zhu Y, Zhang H, Gao L, Zhang Z, Xu X, Ying L, Zhang L, Li Y, Yun Z, Zhu D, Han C, Xu T, Yang H, Ju S, Chen X, Zhang H, Xie J.

Open-Source Throttling of CD8+ T Cells in Brain with Low-Intensity Focused Ultrasound-Guided Sequential Delivery of CXCL10, IL-2, and aPD-L1 for Glioblastoma Immunotherapy

Adv Mater. 2024 Sep 12:e2407235.

 

1125. Fang F, Chen X.

Carrier-Free Nanodrugs: From Bench to Bedside

ACS Nano. 2024 Sep 3;18(35):23827-23841.

 

1124. Zhu Y, Ding C, Fang W, Li T, Yan L, Tian Y, Huang W, Wei P, Ma J, Lin X, Huang W, Lin Y, Zou J, Chen X.

Metal-polyphenol self-assembled nanodots for NIR-II fluorescence imaging-guided chemodynamic/photodynamic therapy-amplified ferroptosis

Acta Biomater. 2024 Sep 1;185:361-370.

 

1123. Xu M, Wu G, You Q, Chen X.

The Landscape of Smart Biomaterial-Based Hydrogen Therapy

Adv Sci (Weinh). 2024 Aug 21:e2401310.

 

1122. Wu Q, Liu SP, Liu C, Chen X, Zhou H, Zhao H.

Disulfidoptosis as a Novel Mechanism of Neuronal Death: Insights from Creutzfeldt-Jakob Disease

World Neurosurg. 2024 Aug 17:S1878-8750(24)01439-6.

 

1121. Tang Y, Zhang J, Yuan Y, Shen K, Luo Z, Jia L, Long X, Peng C, Xie T, Chen X, Zhang P.

Synergistic Gas Therapy and Targeted Interventional Ablation With Size-Controllable Arsenic Sulfide (As2S3) Nanoparticles for Effective Elimination of Localized Cancer Pain

Small. 2024 Oct 2:e2407197.

 

1120. He J, Lin X, Zhang D, Hu H, Chen X, Xu F, Zhou M.

Wake biofilm up to enhance suicidal uptake of gallium for chronic lung infection treatment

Biomaterials. 2024 Oct;310:122619.

 

1119. Wang Q, Zhang C, Zhao Y, Jin Y, Zhou S, Qin J, Zhang W, Hu Y, Chen X, Yang K.

Polyprodrug nanomedicine for chemiexcitation-triggered self-augmented cancer chemotherapy and gas therapy

Biomaterials. 2024 Sep;309:122606.

 

1118. Chen J, Pang Y, Liao X, Zhou Y, Luo Q, Wu H, Zuo C, Zhang J, Lin Q, Chen X, Zhao L, Chen H.

Development of [177Lu]Lu-LNC1010 for peptide receptor radionuclide therapy of nasopharyngeal carcinoma

Eur J Nucl Med Mol Imaging. 2024;52(1):247-259.

 

1117. Zhao X, Jakobsson V, Tao Y, Zhao T, Wang J, Khong PL, Chen X, Zhang J.

Targeted Radionuclide Therapy in Glioblastoma

ACS Appl Mater Interfaces. 2024 Aug 7;16(31):40391-40410.

 

1116. Mo F, Wang C, Li S, Li Z, Xiao C, Zhang Y, Hu C, Wang E, Lin P, Yuan T, Zuo Z, Fu W, Chen X, Ren L, Wang L.

A Dual-Targeting, Multi-Faceted Biocompatible Nanodrug Optimizes the Microenvironment to Ameliorate Abdominal Aortic Aneurysm

Adv Mater. 2024 Aug;36(33):e2405761.

 

1115. Wei Z, Li B, Wen X, Jakobsson V, Liu P, Chen X, Zhang J.

Engineered Antibodies as Cancer Radiotheranostics

Adv Sci (Weinh). 2024 Aug;11(30):e2402361.

 

1114. Zhu L, Li J, Pan J, Wu N, Xu Q, Zhou QQ, Wang Q, Han D, Wang Z, Xu Q, Liu X, Guo J, Wang J, Zhang Z, Wang Y, Cai H, Li Y, Pan H, Zhang L, Chen X, Lu G.

Precise Identification of Glioblastoma Micro-Infiltration at Cellular Resolution by Raman Spectroscopy

Adv Sci (Weinh). 2024 Jul 31:e2401014.

 

1113. Li B, Liu H, Zhao M, Zhang X, Huang P, Chen X, Lin J.

Carboxylesterase Activatable Molecular Probe for Personalized Treatment Guidance by Analyte-Induced Molecular Transformation

Angew Chem Int Ed Engl. 2024 Jul 29;63(31):e202404093.

 

1112. Zhu Y, Ding C, Fang W, Li T, Yan L, Tian Y, Huang W, Wei P, Ma J, Lin X, Huang W, Lin Y, Zou J, Chen X.

Metal-polyphenol self-assembled nanodots for NIR-II fluorescence imaging-guided chemodynamic/ photodynamic therapy-amplified ferroptosis

Acta Biomater. 2024 Jul 23:S1742-7061(24)00388-X.

 

1111. Zhao C, Tang X, Chen X, Jiang Z.

Multifaceted Carbonized Metal-Organic Frameworks Synergize with Immune Checkpoint Inhibitors for Precision and Augmented Cuproptosis Cancer Therapy

ACS Nano. 2024 Jul 9;18(27):17852-17868.

 

1110. Xiang Z, Lu J, Ming Y, Guo W, Chen X, Sun W.

Engineering of a DNA/γPNA Hybrid Nanoreporter for ctDNA Mutation Detection via γPNA Urinalysis

Adv Sci (Weinh). 2024 Jul 3:e2310225.

 

1109. Zhao C, Tang X, Chen X, Jiang Z.

Multifaceted Carbonized Metal-Organic Frameworks Synergize with Immune Checkpoint Inhibitors for Precision and Augmented Cuproptosis Cancer Therapy

ACS Nano. 2024 Jul 9;18(27):17852-17868.

 

1108. Mo F, Wang C, Li S, Li Z, Xiao C, Zhang Y, Hu C, Wang E, Lin P, Yuan T, Zuo Z, Fu W, Chen X, Ren L, Wang L.

A Dual-Targeting, Multi-Faceted Biocompatible Nanodrug Optimizes the Microenvironment to Ameliorate Abdominal Aortic Aneurysm

Adv Mater. 2024 Jun 24:e2405761.

 

1107. Shan L, Li Y, Ma Y, Yang Y, Wang J, Peng L, Wang W, Zhao F, Li W, Chen X.

Hairpin DNA-Based Nanomaterials for Tumor Targeting and Synergistic Therapy

Int J Nanomedicine. 2024 Jun 12;19:5781-5792.

 

1106. Wang Y, Liu C, Ren Y, Song J, Fan K, Gao L, Ji X, Chen X, Zhao H.

Nanomaterial-Based Strategies for Attenuating T-Cell-Mediated Immunodepression in Stroke Patients: Advancing Research Perspectives

Int J Nanomedicine. 2024;19:5793-5812.

 

1105. Wei Z, Li B, Wen X, Jakobsson V, Liu P, Chen X, Zhang J.

Engineered Antibodies as Cancer Radiotheranostics

Adv Sci (Weinh). 2024 Jun 14:e2402361.

 

1104. Mou Z, Zhu Y, Zhang L, Ma M, Li Z, Guo Y, Zheng J, Zhao Z, Zhang K, Chen X, Li Z.

"AquaF" Building Blocks for Water-Compatible SN2 18F-Fluorination of Small-Molecule Radiotracers

J Am Chem Soc. 2024 Jun 13. doi: 10.1021/jacs.4c05854.

 

1103. Hou G, Cheng X, Yang Y, Zhao D, Wang G, Zhao H, Zheng R, Wang X, Chen X, Chi Y, Zhang J.

Diagnostic performance and clinical impact of 18F-AlF-NOTA-octreotide in a large cohort of patients with neuroendocrine neoplasms: A prospective single-center study

Theranostics. 2024;14(8):3213-3220.

 

1102. Yang Q, Ye W, Luo D, Xing J, Xiao Q, Wu H, Yao Y, Wang G, Yang L, Guo D, Wang K, He Y, Ye X, Zhang J, Jin Z, Fan Z, Wen X, Mao J, Chen X, Zhao Q.

Neuroprotective effects of anti-TRAIL-ICG nanoagent and its multimodal imaging evaluation in cerebral ischemia-reperfusion injury

Mater Today Bio. 2024;26:101094.

 

1101. Zhao L, Pang Y, Zhou Y, Chen J, Fu H, Guo W, Xu W, Xue X, Su G, Sun L, Wu H, Zhang J, Wang Z, Lin Q, Chen X, Chen H.

Antitumor efficacy and potential mechanism of FAP-targeted radioligand therapy combined with immune checkpoint blockade

Signal Transduct Target Ther. 2024;9(1):142.

 

1100. He J, Lin X, Zhang D, Hu H, Chen X, Xu F, Zhou M.

Wake biofilm up to enhance suicidal uptake of gallium for chronic lung infection treatment

Biomaterials. 2024;310:122619.

 

1099. Wang Q, Zhang C, Zhao Y, Jin Y, Zhou S, Qin J, Zhang W, Hu Y, Chen X, Yang K.

Polyprodrug nanomedicine for chemiexcitation-triggered self-augmented cancer chemotherapy and gas therapy

Biomaterials. 2024;309:122606.

 

1098. Du Y, Xu J, Han T, Jiang Z, Zhang Y, Li J, Chen X, Zhu S.

Albumin-seeking dyes with adjustable assemblies in situ enable programmable imaging windows and targeting tumor imaging

Theranostics. 2024;14(7):2675-2686.

 

1097. Jiao J, Zhang J, Wen W, Qin W, Chen X.

Prostate-specific membrane antigen-targeted surgery in prostate cancer: Accurate identification, real-time diagnosis, and precise resection

Theranostics. 2024;14(7):2736-2756.

 

1096. Pan Y, Cheng J, Zhu Y, Zhang J, Fan W, Chen X.

Immunological nanomaterials to combat cancer metastasis

Chem Soc Rev. 2024 May 15. doi: 10.1039/d2cs00968d.

 

1095. Li B, Liu H, Zhao M, Zhang X, Huang P, Chen X, Lin J.

Carboxylesterase Activatable Molecular Probe for Personalized Treatment Guidance by Analyte-Induced Molecular Transformation

Angew Chem Int Ed Engl. 2024 May 10:e202404093.

 

1094. Zang J, Yang Y, Chen S, Wang C, Chen S, Hu S, Cai H, Li X, Xu N, Chen X, Zhang J, Miao W.

Diagnostic Performance of [18F]AlF-Thretide PET/CT in Patients with Newly Diagnosed Prostate Cancer Using Histopathology as Reference Standard

J Nucl Med. 2024 May 9:jnumed.123.266940.

 

1093. Liang S, Ma N, Li X, Yun K, Meng QF, Ma K, Yue L, Rao L, Chen X, Wang Z.

A Guanidinobenzol-Rich Polymer Overcoming Cascade Delivery Barriers for CRISPR-Cas9 Genome Editing

Nano Lett. 2024 Apr 29. doi: 10.1021/acs.nanolett.4c00533.

 

1092. Altay Benetti A, Tan EYZ, Chang ZW, Bae KH, Thwin MT, Muthuramalingam RPK, Liao KC, Wan Y, Ng LFP, Renia L, Liu J, Chen X, Yang YY, White KP, Pastorin G.

Design and Characterization of a New Formulation for the Delivery of COVID-19-mRNA Vaccine to the Nasal Mucosa

Vaccines (Basel). 2024 Apr 12;12(4):409.

 

1091. Li Z, Yang J, Ren B, Fan Q, Huang L, Guo S, Zhou R, Chen S, Feng J, Yan C, Chen X, Shen Z.

Double-Layered Hollow Mesoporous Cuprous Oxide Nanoparticles for Double Drug Sequential Therapy of Tumors

Adv Mater. 2024 Apr 26:e2313212.

 

1090. Yang J, Xiong W, Huang L, Li Z, Fan Q, Hu F, Duan X, Fan J, Li B, Feng J, Xu Y, Chen X, Shen Z.

A mesoporous superparamagnetic iron oxide nanoparticle as a generic drug delivery system for tumor ferroptosis therapy

J Nanobiotechnology. 2024;22(1):204.

 

1089. Xiang Z, Lu J, Rao S, Fu C, Yao Y, Yi Y, Ming Y, Sun W, Guo W, Chen X.

Programming peptide-oligonucleotide nano-assembly for engineering of neoantigen vaccine with potent immunogenicity

Theranostics. 2024;14(6):2290-2303.

 

1088. Song Y, Zou J, Castellanos EA, Matsuura N, Ronald JA, Shuhendler A, Weber WA, Gilad AA, Müller C, Witney TH, Chen X.

Theranostics - a sure cure for cancer after 100 years?

Theranostics. 2024;14(6):2464-2488.

 

1087. Kang F, Niu M, Zhou Z, Zhang M, Xiong H, Zeng F, Wang J, Chen X.

Spatiotemporal Concurrent PARP Inhibitor Sensitization based on Radiation-Responsive Nanovesicles for Lung Cancer Chemoradiotherapy

Adv Healthc Mater. 2024 Apr 10:e2400908.

 

1086. Li L, Yin J, Ma W, Tang L, Zou J, Yang L, Du T, Zhao Y, Wang L, Yang Z, Fan C, Chao J, Chen X

A DNA origami device spatially controls CD95 signalling to induce immune tolerance in rheumatoid arthritis

Nat Mater. 2024 Apr 9. doi: 10.1038/s41563-024-01865-5.

 

1085. Zhu Y, Niu X, Ding C, Lin Y, Fang W, Yan L, Cheng J, Zou J, Tian Y, Huang W, Huang W, Pan Y, Wu T, Chen X, Kang D.

Carrier-Free Self-Assembly Nano-Sonosensitizers for Sonodynamic-Amplified Cuproptosis-Ferroptosis in Glioblastoma Therapy

Adv Sci (Weinh). 2024 Apr 6:e2402516.

 

1084. Tan Y, Li J, Zhao T, Zhou M, Liu K, Xiang S, Tang Y, Jakobsson V, Xu P, Chen X, Zhang J.

Clinical translation of a novel FAPI dimer [68Ga]Ga-LNC1013

Eur J Nucl Med Mol Imaging. 2024 Apr 2. doi: 10.1007/s00259-024-06703-z.

 

1083. Li G, Wu S, Liu J, Wang K, Chen X, Liu H.

Narrow Bandgap Schottky Heterojunction Sonosensitizer with High Electron-Hole Separation Boosted Sonodynamic Therapy in Bladder Cancer

Adv Mater. 2024 Mar 28:e2401252.

 

1082. Luo Y, He X, Du Q, Xu L, Xu J, Wang J, Zhang W, Zhong Y, Guo D, Liu Y, Chen X

Metal-based smart nanosystems in cancer immunotherapy

Exploration 2024; 20230134

 

1081. Mu Q, Yao K, Syeda MZ, Wan J, Cheng Q, You Z, Sun R, Zhang Y, Zhang H, Lu Y, Luo Z, Li Y, Liu F, Liu H, Zou X, Zhu Y, Peng K, Huang C, Chen X, Tang L

Neutrophil Targeting Platform Reduces Neutrophil Extracellular Traps for Improved Traumatic Brain Injury and Stroke Theranostics

Adv Sci (Weinh). 2024 Mar 23:e2308719.

 

1080. Zhao Y, Li Q, Niu J, Guo E, Zhao C, Zhang J, Liu X, Wang L, Rao L, Chen X, Yang K.

Neutrophil Membrane-Camouflaged Polyprodrug Nanomedicine for Inflammation Suppression in Ischemic Stroke Therapy

Adv Mater. 2024 Mar 22:e2311803.

 

1079. Di J, Huang P, Chen X.

Targeting Strategies for Site-Specific mRNA Delivery

Bioconjug Chem. 2024 Mar 16. doi: 10.1021/acs.bioconjchem.4c00038.

 

1078. Xiong H, Zhang H, Qin Y, Ye J, Zeng F, Xie P, Shi C, Luo C, Xu W, Yu C, Zhou Z, Chen X.

Coassembly Nanomedicine Mediated by Intermolecular Interactions Between Methotrexate and Baricitinib for Improved Rheumatoid Arthritis Treatment

ACS Nano. 2024 Mar 4. doi: 10.1021/acsnano.3c12692.

 

1077. Zhao C, Wang C, Shan W, Wang Z, Chen X, Deng H.

Nanomedicines for an Enhanced Immunogenic Cell Death-Based In Situ Cancer Vaccination Response

Acc Chem Res. 2024 Feb 28. doi: 10.1021/acs.accounts.3c00771.

 

1076. Zhang X, Wang K, Zhao Z, Shan X, Wang Y, Feng Z, Li B, Luo C, Chen X, Sun J.

Self-Adjuvanting Polyguanidine Nanovaccines for Cancer Immunotherapy

ACS Nano. 2024 Mar 5;18(9):7136-7147.

 

1075. Zou J, Zhang Y, Pan Y, Mao Z, Chen X

Advancing nanotechnology for neoantigen-based cancer theranostics

Chem Soc Rev. 2024 Feb 21. doi: 10.1039/d3cs00162h.

 

1074. Wen X, Wang R, Xu P, Shi M, Shang Q, Zeng X, Zeng X, Liu J, Wang X, Zhu Z, Guo Z, Chen X, Zhang J.

Synthesis, preclinical, and initial clinical evaluation of integrin αVβ3 and gastrin-releasing peptide receptor (GRPR) dual-targeting radiotracer [68Ga]Ga-RGD-RM26-03

Eur J Nucl Med Mol Imaging. 2024 Feb 20. doi: 10.1007/s00259-024-06634-9.

 

1073. Cheng J, Li L, Jin D, Zhang Y, Yu W, Yu J, Zou J, Dai Y, Zhu Y, Liu M, Zhang M, Sun Y, Liu Y, Chen X.

A non-metal single atom nanozyme for cutting off the energy and reducing the power of tumors

Angew Chem Int Ed Engl. 2024 Feb 15:e202319982.

 

1072. Feng Y, Wang J, Cao J, Cao F, Chen X

Manipulating calcium homeostasis with nanoplatforms for enhanced cancer therapy

Exploration. 2024; 4: 20230019. https://doi.org/10.1002/EXP.20230019

 

1071. Sui B, Wang R, Chen C, Kou X, Wu D, Fu Y, Lei F, Wang Y, Liu Y, Chen X, Xu H, Liu Y, Kang J, Liu H, Kin Kwok RT, Tang BZ, Yan H, Wang M, Xiang L, Yan X, Zhang X, Ma L, Shi S, Jin Y.

Apoptotic Vesicular Metabolism Contributes to Organelle Assembly and Safeguards Liver Homeostasis and Regeneration

Gastroenterology. 2024 Feb 9:S0016-5085(24)00136-7. doi: 10.1053/j.gastro.2024.02.001.

 

1070. Wu G, Xian W, You Q, Zhang J, Chen X.

AcousticRobots: Smart acoustically powered micro-/nanoswimmers for precise biomedical applications

Adv Drug Deliv Rev. 2024 Feb 6:115201. doi: 10.1016/j.addr.2024.115201.

 

1069. Zhang Z, Xu X, Du J, Chen X, Xue Y, Zhang J, Yang X, Chen X, Xie J, Ju S.

Redox-responsive polymer micelles co-encapsulating immune checkpoint inhibitors and chemotherapeutic agents for glioblastoma therapy

Nat Commun. 2024;15(1):1118.

 

1068. Zou J, Li Z, Zhu Y, Tao Y, You Q, Cao F, Wu Q, Wu M, Cheng J, Zhu J, Chen X.

pH/GSH dual responsive nanosystem for nitric oxide generation enhanced type I photodynamic therapy

Bioact Mater. 2024;34:414-421.

 

1067. Zheng Y, Zhu X, Jiang M, Cao F, You Q, Chen X.

Development and Applications of D-Amino Acid Derivatives-based Metabolic Labeling of Bacterial Peptidoglycan

Angew Chem Int Ed Engl. 2024 Jan 29:e202319400.

 

1066. Zhong D, Jin K, Wang R, Chen B, Zhang J, Ren C, Chen X, Lu J, Zhou M.

Microalgae-Based Hydrogel for Inflammatory Bowel Disease and Its Associated Anxiety and Depression

Adv Mater. 2024 Jan 26:e2312275.

 

1065. Manoli I, Sysol JR, Head PE, Epping MW, Gavrilova O, Crocker MK, Sloan JL, Koutsoukos SA, Wang CX, Ktena YP, Mendelson S, Pass AR, Zerfas PM, Hoffmann VJ, Vernon HJ, Fletcher LA, Reynolds JC, Tsokos MG, Stratakis CA, Voss SD, Chen KY, Brown RJ, Hamosh A, Berry GT, Chen X, Yanovski JA, Venditti CP.

Lipodystrophy in methylmalonic acidemia associated with elevated FGF21 and abnormal methylmalonylation

JCI Insight. 2024 Jan 25:e174097.

 

1064. Yu H, Tiemuer A, Yao X, Zuo M, Wang HY, Liu Y, Chen X.

Mitochondria-specific near-infrared photoactivation of peroxynitrite upconversion luminescent nanogenerator for precision cancer gas therapy

Acta Pharm Sin B. 2024 Jan;14(1):378-391.

 

1063. Liu N, Wan Q, Wu X, Zhao T, Jakobsson V, Yuan H, Chen X, Zhang J, Zhang W.

A comparison of [18F]AlF- and 68Ga-labeled dual targeting heterodimer FAPI-RGD in malignant tumor: preclinical evaluation and pilot clinical PET/CT imaging

Eur J Nucl Med Mol Imaging. 2024 Jan 22. doi: 10.1007/s00259-023-06587-5.

 

1062. Nie S, Qin Y, Ou L, Chen X, Li L.

In Situ Reprogramming of Immune Cells Using Synthetic Nanomaterials

Adv Mater. 2024 Jan 17:e2310168.

 

1061. Zou J, Li Z, Zhu Y, Tao Y, You Q, Cao F, Wu Q, Wu M, Cheng J, Zhu J, Chen X

pH/GSH dual responsive nanosystem for nitric oxide generation enhanced type I photodynamic therapy

Bioactive Mater. 2024;34:414-421.

 

1060. Sun T, Wang H, Zhang X, Ling P, Xiao Y, Chen Q, Chen X

Ion Monitoring at Nanoscale Sites of Interorganelle Membrane Contact in Living Cells

Small Structures. https://doi.org/10.1002/sstr.202300350

 

1059. Zhang M, Kang F, Xing T, Wang J, Ma T, Li G, Quan Z, Yang W, Chen X, Wang J.

First-in-human validation of enzymolysis clearance strategy for decreasing renal radioactivity using modified [68Ga]Ga-HER2 Affibody

Eur J Nucl Med Mol Imaging. 2024 Jan 13. doi: 10.1007/s00259-023-06584-8.

 

1058. Liu J, Zhang Y, Yang B, Jia Y, Liu RT, Ding L, Shen Z, Chen X.

Synergistic Glutathione Depletion and STING Activation to Potentiate Dendritic Cell Maturation and Cancer Vaccine Efficacy

Angew Chem Int Ed Engl. 2024 Jan 9:e202318530.

 

1057. Baum RP, Fan X, Jakobsson V, Yu F, Schuchardt C, Chen X, Zhang J.

Long-term Nephrotoxicity after PRRT: Myth or Reality

Theranostics. 2024;14(2):451-459.

 

1056. Chen L, Zhang J, Chi C, Che W, Dong G, Wang J, Du Y, Wang R, Zhu Z, Tian J, Ji N, Chen X, Li D.

Lower-grade gliomas surgery guided by GRPR-targeting PET/NIR dual-modality image probe: a prospective and single-arm clinical trial

Theranostics. 2024;14(2):819-829.

 

1055. Wang Y, Yin Q, Yang D, Jin H, Yao Y, Song J, Liu C, Nie Y, Yin H, Wang W, Xu B, Xue L, Ji X, Chen X, Zhao H.

LCP1 knockdown in monocyte-derived macrophages: mitigating ischemic brain injury and shaping immune cell signaling and metabolism

Theranostics. 2024 Jan 1;14(1):159-175.

 

1054. Pijeira MSO, Nunes PSG, Chaviano SL, Diaz AMA, DaSilva JN, Ricci-Junior E, Alencar LMR, Chen X, Santos-Oliveira R.

Medicinal (Radio)Chemistry: Building Radiopharmaceuticals for the Future

Curr Med Chem. 2023 Aug 18. doi: 10.2174/0929867331666230818092634.

 

1053. Xu W, Cai J, Peng T, Meng T, Pang Y, Sun L, Wu H, Zhang J, Chen X, Chen H.

Fibroblast Activation Protein-Targeted PET/CT with 18F-Fibroblast Activation Protein Inhibitor-74 for Evaluation of Gastrointestinal Cancer: Comparison with 18F-FDG PET/CT

J Nucl Med. 2024;65(1):40-51.

 

1052. Zang J, Wang G, Zhao T, Liu H, Lin X, Yang Y, Shao Z, Wang C, Chen H, Chen Y, Zhu Z, Miao W, Chen X, Zhang J.

A phase 1 trial to determine the maximum tolerated dose and patient-specific dosimetry of [177Lu]Lu-LNC1003 in patients with metastatic castration-resistant prostate cancer

Eur J Nucl Med Mol Imaging. 2024;51(3):871-882.

 

1051. Feng Z, Zhang X, Zhou J, Li Q, Chu L, Di G, Xu Z, Chen Q, Wang M, Jiang X, Xia H, Chen X.

An in vitro-transcribed circular RNA targets the mitochondrial inner membrane cardiolipin to ablate EIF4G2+/PTBP1+ pan-adenocarcinoma

Nat Cancer. 2023 Oct 16. doi: 10.1038/s43018-023-00650-8.

 

1050. Lin R, Wang C, Chen S, Lin T, Cai H, Chen S, Yang Y, Zhang J, Xu F, Zhang J, Chen X, Zang J, Miao W.

[68Ga]Ga‑LNC1007 PET/CT in the evaluation of renal cell carcinoma: comparison with 2-[18F]FDG/[68Ga]Ga-PSMA PET/CT

Eur J Nucl Med Mol Imaging. 2024;51(2):535-547.

1049. Yu M, Ye Z, Liu S, Zhu Y, Niu X, Wang J, Ao R, Huang H, Cai H, Liu Y, Chen X, Lin L.

Redox-Active Ferrocene Quencher-Based Supramolecular Nanomedicine for NIR-II Fluorescence-Monitored Chemodynamic Therapy

Angew Chem Int Ed Engl. 2023 Dec 18:e202318155.

 

1048. Zhang P, Yao S, Tang Y, Wan S, Chen X, Ma L.

A Side-Effect-Free Interventional Therapy for Precisely Eliminating Unresectable Cancer Pain

ACS Nano. 2023 Dec 12;17(23):23535-23544.

 

1047. Zhang P, Yao S, Tang Y, Wan S, Chen X, Ma L.

A Side-Effect-Free Interventional Therapy for Precisely Eliminating Unresectable Cancer Pain

ACS Nano. 2023;17(23):23535-23544.

 

1046. Zhou QQ, Guo J, Wang Z, Li J, Chen M, Xu Q, Zhu L, Xu Q, Wang Q, Pan H, Pan J, Zhu Y, Song M, Liu X, Wang J, Zhang Z, Zhang L, Wang Y, Cai H, Chen X, Lu G.

Rapid visualization of PD-L1 expression level in glioblastoma immune microenvironment via machine learning cascade-based Raman histopathology

J Adv Res. 2023 Dec 8:S2090-1232(23)00377-6.

 

1045. Baum RP, Fan X, Jakobsson V, Schuchardt C, Chen X, Yu F, Zhang J.

Extended peptide receptor radionuclide therapy: evaluating nephrotoxicity and therapeutic effectiveness in neuroendocrine tumor patients receiving more than four treatment cycles

Eur J Nucl Med Mol Imaging. 2023 Dec 2. doi: 10.1007/s00259-023-06544-2.

 

1044. Yu X, Qi S, Cao F, Yang K, Li H, Peng K, Liu Z, Bai B, Buljan M, Chen X, Yu G.

Fabrication of An Immunostimulatory Supramolecular Nanomedicine for Potent Cancer Chemoimmunotherapy

JACS Au. 2023 Nov 7;3(11):3181-3193.

 

1043. Li Y, Guo Y, Zhang K, Zhu R, Chen X, Zhang Z, Yang W.

Cell Death Pathway Regulation by Functional Nanomedicines for Robust Antitumor Immunity

Adv Sci (Weinh). 2023 Nov 20:e2306580.

 

1042. Liu J, Zhan J, Zhang Y, Huang L, Yang J, Feng J, Ding L, Shen Z, Chen X.

Ultrathin Clay Nanoparticles-Mediated Mutual Reinforcement of Ferroptosis and Cancer Immunotherapy

Adv Mater. 2023 Nov 8:e2309562.

 

1041. Huang P, Deng H, Wang C, Zhou Y, Chen X.

Cellular Trafficking of Nanotechnology-Mediated mRNA Delivery

Adv Mater. 2023 Nov 6:e2307822.

 

1040. Song M, Li L, Liu J, Gao Y, Li M, Zhou L, Qin B, Xiang A, Sun X, Fan W, Lei Y, Chen X.

Peroxynitrite-Scavenging Organosilica Nanomedicines for Light-Controllable NO Release and Precision On-Demand Glaucoma Therapy

ACS Nano. 2023;17(21):20979-20990.

 

1039. Huang R, Zhou P, Chen B, Zhu Y, Chen X, Min Y.

Stimuli-Responsive Nanoadjuvant Rejuvenates Robust Immune Responses to Sensitize Cancer Immunotherapy

ACS Nano. 2023;17(21):21455-21469.

 

1038. Wang K, Zhang X, Ye H, Wang X, Fan Z, Lu Q, Li S, Zhao J, Zheng S, He Z, Ni Q, Chen X, Sun J.

Biomimetic nanovaccine-mediated multivalent IL-15 self-transpresentation (MIST) for potent and safe cancer immunotherapy

Nat Commun. 2023;14(1):6748.

 

1037. Chen Y, Zou T, Xin G, Liu X, Yang Y, Wei L, Zhang B, Yu P, Ren Y, Feng Y, Chen R, Cao F, Chen X, Cheng Y.

Oxygen-Independent Synchronized Ros Generation and Hypoxia Prodrug Activation with Z-Scheme Heterostructure Sonosensitizer

Adv Mater. 2023 Oct 19:e2307929.

 

1036. Li C, Chen X, Zhang J.

Comment on: "Development of a CLDN18.2-targeting immuno-PET probe for non-invasive imaging in gastrointestinal tumors"

J Pharm Anal. 2023 Sep;13(9):958-959.

 

1035. Fu H, Huang J, Zhao T, Wang H, Chen Y, Xu W, Pang Y, Guo W, Sun L, Wu H, Xu P, Su B, Zhang J, Chen X, Chen H.

Fibroblast Activation Protein-Targeted Radioligand Therapy with 177Lu-EB-FAPI for Metastatic Radioiodine Refractory Thyroid Cancer: First-in-Human, Dose-Escalation Study

Clin Cancer Res. 2023;29(23):4740-4750.

 

1034. Cao F, Jin L, Zhang C, Gao Y, Qian Z, Wen H, Yang S, Ye Z, Hong L, Yang H, Tong Z, Cheng L, Ding Y, Wang W, Yu G, Mao Z, Chen X.

Engineering Clinically Relevant Probiotics with Switchable "nano-promoter" and "nano-effector" for Precision Tumor Therapy

Adv Mater. 2023 Oct 3:e2304257.

 

1033. Guo S, Gu D, Yang Y, Tian J, Chen X.

Near-infrared photodynamic and photothermal co-therapy based on organic small molecular dyes

J Nanobiotechnology. 2023 Sep 27;21(1):348.

 

1032. Liu D, Liang S, Ma K, Meng QF, Li X, Wei J, Zhou M, Yun K, Pan Y, Rao L, Chen X, Wang Z.

Tumor Microenvironment-Responsive Nanoparticles Amplifying STING Signaling Pathway for Cancer Immunotherapy

Adv Mater. 2023 Sep 18:e2304845.

 

1031. Fan Q, Xiong W, Zhou H, Yang J, Feng J, Li Z, Wu L, Hu F, Duan X, Li B, Fan J, Xu Y, Chen X, Shen Z.

An and Logic Gate for Magnetic Resonance Imaging-Guided Ferroptosis Therapy of Tumors

Adv Mater. 2023 Sep 17:e2305932.

 

1030. Wu Q, Zhang Y, Jia G, Hou M, Jiang Y, Wei W, Liu P, Huang G, Zou J, Zhang J, Hai W, Zhang M, Li B, Chen X, Zhang C

A sequential dual-locked strategy with pH-responsive activation of photosensitizers and precise Cerenkov radiation delivery for cancer theranostics

Nano Today 2023; 52: 101984

 

1029. Zhang J, Zhao T, Jakobsson V, Chen X

Clinical translation of radiotheranostics for precision oncology

Nat Rev Bioeng 2023;1:612-4.

 

1028. You Q, Liang F, Wu G, Cao F, Liu J, He Z, Wang C, Zhu L, Chen X, Yang Y

The Landscape of Biomimetic Nanovesicles in Brain Diseases

Adv Mater. 2023 Sep 15:e2306583.

 

1027. Shi C, Zhang X, Liu X, Chen X, Zhou Z.

Theranostics on the immunoactivity of T cells

Clin Transl Med. 2023;13(9):e1421.

 

1026. Zang J, Lin R, Wen X, Wang C, Zhao T, Jakobsson V, Yang Y, Wu X, Guo Z, Chen X, Zhang J, Miao W.

A Head-to-Head Comparison of 68Ga-LNC1007 and 2-18F-FDG/68Ga-FAPI-02 PET/CT in Patients With Various Cancers

Clin Nucl Med. 2023;48(10):861-868.

 

1025. Ruan D, Zhao L, Cai J, Xu W, Sun L, Li J, Zhang J, Chen X, Chen H.

Evaluation of FAPI PET imaging in gastric cancer: a systematic review and meta-analysis

Theranostics. 2023;13(13):4694-4710.

 

1024. Tao Y, Jakobsson V, Chen X, Zhang J.

Exploiting Albumin as a Versatile Carrier for Cancer Theranostics

Acc Chem Res. 2023;56(18):2403-2415.

 

1023. Wang L, Li Q, Cao P, Zhang J, Wu D, Xu R, Zhang Y, Xu Y, Liang T, Chen W, Wang Z, Chen X

A biomimetic micro-robotic swimmer actuated by rotating magnetic field for targeted navigation and localized NIR-based prodrug activation to treat intestinal diseases

Device. 2023; 1: 100064

 

1022. Pijeira MSO, Nunes PSG, Chaviano SL, Diaz AMA, DaSilva JN, Ricci-Junior E, Alencar LMR, Chen X, Santos-Oliveira R.

Medicinal (Radio)Chemistry: Building Radiopharmaceuticals for the Future

Curr Med Chem. 2023 Aug 18. doi: 10.2174/0929867331666230818092634.

 

1021. Zheng C, Zhong Q, Yi K, Kong H, Cao F, Zhuo C, Xu Y, Shi R, Ju E, Song W, Tao Y, Chen X, Li M.

Anti-phagocytosis-blocking repolarization-resistant membrane-fusogenic liposome (ARMFUL) for adoptive cell immunotherapy

Sci Adv. 2023;9(32):eadh2413.

 

1020. Gong Y, Tong S, Li X, Chen X, Liu Y, Li N, Xu J, Xu R, Guo Y, Xiao F, Chen X, Chen W.

Intestinal Villi-Inspired Mathematically Base-Layer Engineered Microneedles (IMBEMs) for Effective Molecular Exchange during Biomarker Enrichment and Drug Deposition in Diversified Mucosa

ACS Nano. 2023;17(16):15696-15712.

 

1019. Hu X, Zhu C, Sun F, Chen Z, Zou J, Chen X, Yang Z.

J-Aggregation Strategy Toward Potentiated NIR-II Fluorescence Bioimaging of Molecular Fluorophores

Adv Mater. 2023 Aug 1:e2304848.

 

1018. Zhang Y, Wang L, Zhang C, Zhang J, Yuan L, Jin S, Zhou W, Guan X, Kang P, Zhang C, Tian J, Chen X, Li D, Jia W.

Preclinical assessment of IRDye800CW-labeled gastrin-releasing peptide receptor-targeting peptide for near infrared-II imaging of brain malignancies

Bioeng Transl Med. 2023;8(4):e10532.

 

1017. Xing B, Chen XS.

Preface in special theme: Functional inorganic nanomaterials for cutting-edge theranostic applications.

Adv Drug Deliv Rev. 2023;199:114991.

 

1016. Chong SY, Wang X, van Bloois L, Huang C, Syeda NS, Zhang S, Ting HJ, Nair V, Lin Y, Lou CKL, Benetti AA, Yu X, Lim NJY, Tan MS, Lim HY, Lim SY, Thiam CH, Looi WD, Zharkova O, Chew NWS, Ng CH, Bonney GK, Muthiah M, Chen X, Pastorin G, Richards AM, Angeli V, Storm G, Wang JW.

Injectable liposomal docosahexaenoic acid alleviates atherosclerosis progression and enhances plaque stability

J Control Release. 2023;360:344-364.

 

1015. You Q, Shao X, Wang J, Chen X.

Progress on Physical Field-Regulated Micro/Nanomotors for Cardiovascular and Cerebrovascular Disease Treatment

Small Methods. 2023:e2300426.

 

1014. Meng QF, Tai W, Tian M, Zhuang X, Pan Y, Lai J, Xu Y, Xu Z, Li M, Zhao G, Yu GT, Yu G, Chen R, Jin N, Li X, Cheng G, Chen X, Rao L.

Inhalation delivery of dexamethasone with iSEND nanoparticles attenuates the COVID-19 cytokine storm in mice and nonhuman primates

Sci Adv. 2023 Jun 16;9(24):eadg3277.

 

1013. Huang P, Wang C, Deng H, Zhou Y, Chen X.

Surface Engineering of Nanoparticles toward Cancer Theranostics

Acc Chem Res. 2023;56(13):1766-1779.

 

1012. Hu H, Hua SY, Lin X, Lu F, Zhang W, Zhou L, Cui J, Wang R, Xia J, Xu F, Chen X, Zhou M

Hybrid Biomimetic Membrane Coated Particles-Mediated Bacterial Ferroptosis for Acute MRSA Pneumonia

ACS Nano. 2023;17(12):11692-11712.

 

1011. Wang R, Jakobsson V, Wang J, Zhao T, Peng X, Li B, Xue J, Liang N, Zhu Z, Chen X, Zhang J.

Dual targeting PET tracer [68Ga]Ga-FAPI-RGD in patients with lung neoplasms: a pilot exploratory study

Theranostics. 2023 May 15;13(9):2979-2992.

 

1010. Zhang J, Schuchardt C, Chen X, Baum RP.

Rapid Tumor Washout of 177Lu-PSMA Radioligand in Renal Cell Carcinoma

Clin Nucl Med. 2023;48(8):732-734.

 

1009. Wang K, Li Y, Wang X, Zhang Z, Cao L, Fan X, Wan B, Liu F, Zhang X, He Z, Zhou Y, Wang D, Sun J, Chen X.

Gas therapy potentiates aggregation-induced emission luminogen-based photoimmunotherapy of poorly immunogenic tumors through cGAS-STING pathway activation

Nat Commun. 2023 May 23;14(1):2950.

 

1008. Zhu J, Zhang Y, Li Z, Bao X, Zhou Y, Ma B, Xie Y, Yan P, Wu Z, Zhang Q, Zou J, Chen X.

Tumor-microenvironment-responsive poly-prodrug encapsulated semiconducting polymer nanosystem for phototherapy-boosted chemotherapy

Mater Horiz. 2023;10(8):3014-3023.

 

1007. Gu W, An J, Li Y, Yang Y, Wang S, Shan H, Li S, Li H, Liu G, Li K, Yin Y, Mu J, Chen X.

Tuning the Organ Tropism of Polymersome for Spleen-Selective Nanovaccine Delivery to Boost Cancer Immunotherapy

Adv Mater. 2023 May 11:e2301686.

 

1006. Feng X, Wei L, Liu Y, Chen X, Tian R.

Orchestrated strategies for developing fluorophores for NIR-II imaging

Adv Healthc Mater. 2023 May 10:e2300537.

 

1005. Zhao L, Wen X, Xu W, Pang Y, Sun L, Wu X, Xu P, Zhang J, Guo Z, Lin Q, Chen X, Chen H.

Clinical Evaluation of 68Ga-FAPI-RGD for Imaging of Fibroblast Activation Protein and Integrin αvβ3 in Various Cancer Types

J Nucl Med. 2023;64(8):1210-1217.

 

1004. Cheng J, Zhu Y, Dai Y, Li L, Zhang M, Jin D, Liu M, Yu J, Yu W, Su D, Zou J, Chen X, Liu Y.

Gas-Mediated Tumor Energy Remodeling for Sensitizing Mild Photothermal Therapy

Angew Chem Int Ed Engl. 2023 May 3:e202304312. doi: 10.1002/anie.202304312.

 

1003. Wen X, Xu P, Zeng X, Liu J, Du C, Zeng X, Cheng X, Wang X, Liang Y, Zhao T, Yang H, Li H, Meng L, Fang J, Liu H, Zhou Z, Zhang J, Zhang X, Guo Z, Chen X

Development of [177Lu]Lu-LNC1003 for radioligand therapy of prostate cancer with a moderate level of PSMA expression

Eur J Nucl Med Mol Imaging. 2023;50(9):2846-2860.

 

1002. Mu Q, Yao K, Syeda MZ, Zhang M, Cheng Q, Zhang Y, Sun R, Lu Y, Zhang H, Luo Z, Huang H, Liu X, Luo C, Zhu X, Wu S, Cui L, Huang C, Chen X, Tang L.

Ligustrazine Nanoparticle Hitchhiking on Neutrophils for Enhanced Therapy of Cerebral Ischemia-Reperfusion Injury

Adv Sci (Weinh). 2023 Apr 20:e2301348.

 

1001. Jiang Y, Liu Q, Wang G, Zhang J, Zhu Z, Chen X.

Evaluation of Safety, Biodistribution, and Dosimetry of a Long-Acting Radiolabeled Somatostatin Analog 177Lu-DOTA-EB-TATE With and Without Amino Acid Infusion

Clin Nucl Med. 2023;48(6):e289-e293

 

1000. Li B, Zhao M, Lai W, Zhang X, Yang B, Chen X, Ni Q.

Activatable NIR-II Photothermal Lipid Nanoparticles for Improved Messenger RNA Delivery

Angew Chem Int Ed Engl. 2023 Apr 19:e202302676.

 

999. Yang W, Yi J, Zhu R, Guo Y, Zhang K, Cao Y, Li X, Zhang J, Zhang Z, Li Y, Chen X.

Transformable prodrug nanoplatform via tumor microenvironment modulation and immune checkpoint blockade potentiates immunogenic cell death mediated cancer immunotherapy

Theranostics. 2023;13(6):1906-1920.

 

998. Zhu Y, Liao Y, Zou J, Cheng J, Pan Y, Lin L, Chen X.

Engineering Single-Atom Nanozymes for Catalytic Biomedical Applications

Small. 2023 Apr 14:e2300750.

 

997. Tong L, Zhang S, Liu Q, Huang C, Hao H, Tan MS, Yu X, Lou CKL, Huang R, Zhang Z, Liu T, Gong P, Ng CH, Muthiah M, Pastorin G, Wacker MG, Chen X, Storm G, Lee CN, Zhang L, Yi H, Wang JW.

Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis

Sci Adv. 2023;9(15):eade5041.

 

996. Hua Y, Shao ZH, Zhai A, Zhang LJ, Wang ZY, Zhao G, Xie F, Liu JQ, Zhao X, Chen X, Zang SQ.

Water-Soluble Au25 Clusters with Single-Crystal Structure for Mitochondria-Targeting Radioimmunotherapy

ACS Nano. 2023;17(8):7837-7846.

 

995. Zhang X, Yang B, Ni Q, Chen X

Materials engineering strategies for cancer vaccine adjuvant development

Chem Soc Rev. 2023;52(9):2886-2910.

 

994. Cao F, Jin L, Gao Y, Ding Y, Wen H, Qian Z, Zhang C, Hong L, Yang H, Zhang J, Tong Z, Wang W, Chen X, Mao Z.

Artificial-enzymes-armed Bifidobacterium longum probiotics for alleviating intestinal inflammation and microbiota dysbiosis

Nat Nanotechnol. 2023;18(6):617-627.

 

993. Wang J, Ding H, Zhu Y, Liu Y, Yu M, Cai H, Ao R, Huang H, Gong P, Liao Y, Chen Z, Lin L, Chen X, Yang H.

Iron-siRNA Nanohybrids for Enhanced Chemodynamic Therapy via Ferritin Heavy Chain Downregulation

Angew Chem Int Ed Engl. 2023 Mar 23:e202302255.

 

992. Yang L, Lang Y, Wu H, Xiang K, Wang Y, Yu M, Liu Y, Yang B, He L, Lu G, Ni Q, Chen X, Zhang L.

Engineered Toll-like Receptor Nanoagonist Binding to Extracellular Matrix Elicits Safe and Robust Antitumor Immunity

ACS Nano. 2023;17(6):5340-5353.

 

991. Zeng F, Nijiati S, Liu Y, Yang Q, Liu X, Zhang Q, Chen S, Su A, Xiong H, Shi C, Cai C, Lin Z, Chen X, Zhou Z.

Ferroptosis MRI for early detection of anticancer drug-induced acute cardiac/kidney injuries

Sci Adv. 2023;9(10):eadd8539.

 

990. Liang S, Yao J, Liu D, Rao L, Chen X, Wang Z.

Harnessing Nanomaterials for Cancer Sonodynamic Immunotherapy

Adv Mater. 2023 Mar 7:e2211130.

 

989. Song Y, You Q, Chen X

Transition Metal-based Therapies for Inflammatory Diseases

Adv Mater. 2023 Mar 2:e2212102.

 

988. Zhao M, Zhuang H, Li B, Chen M, Chen X

In Situ Transformable Nanoplatforms with Supramolecular Cross-Linking Triggered Complementary Function for Enhanced Cancer Photodynamic Therapy

Adv Mater. 2023 Mar 1:e2209944.

 

987. Zeng F, Nijiati S, Tang L, Ye J, Zhou Z, Chen X

Ferroptosis Detection: From Approaches to Applications

Angew Chem Int Ed Engl. 2023 Feb 24:e202300379.

 

986. Feng Z, Jing Z, Li Q, Chu L, Jiang Y, Zhang X, Yan L, Liu Y, Jiang J, Xu P, Chen Q, Wang M, Yang H, Zhou G, Jiang X, Chen X, Xia H.

Exosomal STIMATE derived from type II alveolar epithelial cells controls metabolic reprogramming of tissue-resident alveolar macrophages

Theranostics. 2023;13(3):991-1009.

 

985. Jiang Z, He L, Yang Z, Qiu H, Chen X, Yu X, Li W

Ultra-wideband-responsive photon conversion through co-sensitization in lanthanide nanocrystals

Nat Commun. 2023;14(1):827.

 

984. Liu L, Pan Y, Zhao C, Huang P, Chen X, Rao L

Boosting Checkpoint Immunotherapy with Biomaterials

ACS Nano. 2023 Feb 28;17(4):3225-3258.

 

983. Liu Q, Kulkarni HR, Zhao T, Schuchardt C, Chen X, Zhu Z, Zhang J, Baum RP

Peptide Receptor Radionuclide Therapy in Patients With Advanced Progressive Medullary Thyroid Cancer: Efficacy, Safety, and Survival Predictors

Clin Nucl Med. 2023;48(3):221-227.

 

982. Zhao C, Pan Y, Yu G, Zhao XZ, Chen X, Rao L.

Vesicular Antibodies: Shedding Light on Antibody Therapeutics with Cell Membrane Nanotechnology

Adv Mater. 2023;35(12):e2207875.

 

981. Cheng J, Li L, Jin D, Dai Y, Zhu Y, Zou J, Liu M, Yu W, Yu J, Sun Y, Chen X, Liu Y.

Boosting Ferroptosis Therapy with Iridium Single-Atom Nanocatalyst in Ultralow Metal Content

Adv Mater. 2023 Jan 31:e2210037.

 

980. Zhu Y, Gong P, Wang J, Cheng J, Wang W, Cai H, Ao R, Huang H, Yu M, Lin L, Chen X.

Amplification of Lipid Peroxidation by Regulating Cell Membrane Unsaturation To Enhance Chemodynamic Therapy

Angew Chem Int Ed Engl. 2023;62(12):e202218407.

 

979. Zhao D, Huang X, Tian Y, Zou J, Wang F, Chen X

Fluorescence Imaging-Incorporated Transcriptome Study of Glutathione Depletion-Enhanced Ferroptosis Therapy via Targeting Gold Nanoclusters

ACS Appl Mater Interfaces. 2023 Feb 8;15(5):6385-6396.

 

978. Zhu Y, Wang W, Gong P, Zhao Y, Pan Y, Zou J, Ao R, Wang J, Cai H, Huang H, Yu M, Wang H, Lin L, Chen X, Wu Y.

Enhancing Catalytic Activity of a Nickel Single Atom Enzyme by Polynary Heteroatom Doping for Ferroptosis-Based Tumor Therapy

ACS Nano. 2023;17(3):3064-3076.

 

977. Cheng Q, Yang Z, Quan X, Ding Y, Li J, Wang Z, Zhao Y, Chen X, Wang R.

Tumor polyamines as guest cues attract host-functionalized liposomes for targeting and hunting via a bio-orthogonal supramolecular strategy.

Theranostics. 2023 Jan 1;13(2):611-620.

 

976. Feng Y, Ning X, Wang J, Wen Z, Cao F, You Q, Zou J, Zhou X, Sun T, Cao J, Chen X.

Mace-Like Plasmonic Au-Pd Heterostructures Boost Near-Infrared Photoimmunotherapy.

Adv Sci (Weinh). 2023 Jan 4:e2204842.

975. Shi M, Jakobsson V, Greifenstein L, Khong PL, Chen X, Baum RP, Zhang J.

Alpha-peptide receptor radionuclide therapy using actinium-225 labeled somatostatin receptor agonists and antagonists.

Front Med (Lausanne). 2022 Dec 7;9:1034315.

 

974. Shi C, Zhang Q, Yao Y, Zeng F, Du C, Nijiati S, Wen X, Zhang X, Yang H, Chen H, Guo Z, Zhang X, Gao J, Guo W, Chen X, Zhou Z.

Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics.

Nat Nanotechnol. 2023;18(1):86-97.

 

973. Li Z, Zou J, Chen X.

In Response to Precision Medicine: Current Subcellular Targeting Strategies for Cancer Therapy.

Adv Mater. 2022 Nov 29:e2209529.

 

972. Satalkar V, Benassi E, Mao Y, Pan X, Ran C, Chen X, Shao Y.

Computational Investigation of Substituent Effects on the Fluorescence Wavelengths of Oxyluciferin Analogs.

J Photochem Photobiol A Chem. 2022 Oct 1;431:114018.

 

971. Lu Y, Liang Z, Feng J, Huang L, Guo S, Yi P, Xiong W, Chen S, Yang S, Xu Y, Li Y, Chen X, Shen Z

Facile Synthesis of Weakly Ferromagnetic Organogadolinium Macrochelates-Based T1 -Weighted Magnetic Resonance Imaging Contrast Agents

Adv Sci (Weinh). 2022 Nov 15:e2205109. doi: 10.1002/advs.202205109.

 

970. He L, Zheng N, Wang Q, Du J, Wang S, Cao Z, Wang Z, Chen G, Mu J, Liu S, Chen X

Responsive Accumulation of Nanohybrids to Boost NIR-Phototheranostics for Specific Tumor Imaging and Glutathione Depletion-Enhanced Synergistic Therapy

Adv Sci (Weinh). 2022 Nov 14:e2205208. doi: 10.1002/advs.202205208.

 

969. Pan Y, Tang W, Fan W, Zhang J, Chen X

Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection

Chem Soc Rev. 2022 Nov 10. doi: 10.1039/d1cs01145f.

 

968. Wang G, Zang J, Jiang Y, Liu Q, Sui H, Wang R, Fan X, Zhang J, Zhu Z, Chen X

A single-arm, low-dose, prospective study of 177Lu-EB-PSMA radioligand therapy in patients with metastatic castration-resistant prostate cancer

J Nucl Med. 2022 Nov 3:jnumed.122.264857. doi: 10.2967/jnumed.122.264857.

 

967. Huang P, Jiang L, Pan H, Ding L, Zhou B, Zhao M, Zou J, Li B, Qi M, Deng H, Zhou Y, Chen X.

Integrated Polymeric mRNA Vaccine without Inflammation Side-Effects for Cellular Immunity Mediated Cancer Therapy

Adv Mater. 2022 Nov 3:e2207471. doi: 10.1002/adma.202207471.

 

966. Pan Y, Zhu Y, Xu C, Pan C, Shi Y, Zou J, Li Y, Hu X, Zhou B, Zhao C, Gao Q, Zhang J, Wu A, Chen X, Li J.

Biomimetic Yolk-Shell Nanocatalysts for Activatable Dual-Modal-Image-Guided Triple-Augmented Chemodynamic Therapy of Cancer

ACS Nano. 2022 Oct 31. doi: 10.1021/acsnano.2c08077.

 

965. Ye Y, He J, Wang H, Li W, Wang Q, Luo C, Tang X, Chen X, Jin X, Yao K, Zhou M.

Cell Wall Destruction and Internal Cascade Synergistic Antifungal Strategy for Fungal Keratitis

ACS Nano. 2022 Oct 24. doi: 10.1021/acsnano.2c07444.

 

964. Zang J, Wen X, Lin R, Zeng X, Wang C, Shi M, Zeng X, Zhang J, Wu X, Zhang X, Miao W, Xu P, Guo Z, Zhang J, Chen X

Synthesis, preclinical evaluation and radiation dosimetry of a dual targeting PET tracer [68Ga]Ga-FAPI-RGD

Theranostics. 2022;12(16):7180-7190.

 

963. Li M, Zheng X, Han T, Ma S, Wang Y, Sun B, Xu J, Wang X, Zhang S, Zhu S, Chen X.

Near-infrared-II ratiometric fluorescence probes for non-invasive detection and precise navigation surgery of metastatic sentinel lymph nodes

Theranostics. 2022;12(16):7191-7202.

 

962. Zhang L, Jiang Z, Yang X, Qian Y, Wang M, Wu S, Li L, Jia F, Wang Z, Hu Z, Zhao M, Tang X, Li G, Shang H, Chen X, Wang W.

Totipotent "All-in-one" Peptide Sequentially Blocks Immune Checkpoint and Reverses Immunosuppressive Tumor Microenvironment

Adv Mater. 2022 Oct 19:e2207330.

 

961. Zhang Y, Li J, Liu C, Zheng K, Zhang B, Zhou Y, Dai C, Fan S, Yao Y, Zhuang R, Guo D, Huang Z, Mao J, Liang J, Yang H, Wang L, Liu G, Chen X, Zhao Q.

Development of a multi-scene universal multiple wavelet-FFT algorithm (MW-FFTA) for denoising motion artifacts in OCT-angiography in vivo imaging

Opt Express. 2022;30(20):35854-35870.

 

960. Wen X, Zeng X, Liu J, Zhang Y, Shi C, Wu X, Zhuang R, Chen X, Zhang X, Guo Z.

Synergism of 64Cu-Labeled RGD with Anti-PD-L1 Immunotherapy for the Long-Acting Antitumor Effect

Bioconjug Chem. 2022 Oct 18. doi: 10.1021/acs.bioconjchem.2c00408.

 

959. Pang Y, Zhao L, Meng T, Xu W, Lin Q, Wu H, Zhang J, Chen X, Sun L, Chen H.

PET imaging of fibroblast activation protein in various types of cancers by using 68Ga-FAP-2286: Comparison with 18F-FDG and 68Ga-FAPI-46 in a single-center, prospective study

J Nucl Med. 2022 Sep 2:jnumed.122.264544.

 

958. Jiang Y, Liu Q, Wang G, Sui H, Wang R, Wang J, Zhang J, Zhu Z, Chen X.

Safety and efficacy of peptide receptor radionuclide therapy with 177Lu-DOTA-EB-TATE in patients with metastatic neuroendocrine tumors

Theranostics. 2022;12(15):6437-6445.

 

957. Zhao M, Zhuang H, Zhang H, Li B, Ming J, Chen X, Chen M.

A LRET Nanoplatform Consisting of Lanthanide and Amorphous Manganese Oxide for NIR-II Luminescence Lifetime Imaging of Tumor Redox Status

Angew Chem Int Ed Engl. 2022 Sep 29:e202209592. doi: 10.1002/anie.202209592.

 

956. Jiang Y, Liu Q, Wang G, Sui H, Wang R, Wang J, Zhang J, Zhu Z, Chen X.

Safety and efficacy of peptide receptor radionuclide therapy with 177Lu-DOTA-EB-TATE in patients with metastatic neuroendocrine tumors

Theranostics 2022; 12(15):6437-6445.

 

955. Wang X, Sun W, Shi H, Ma H, Niu G, Li Y, Zhi J, Yao X, Song Z, Chen L, Li S, Yang G, Zhou Z, He Y, Qu S, Wu M, Zhao Z, Yin C, Lin C, Gao J, Li Q, Zhen X, Li L, Chen X, Liu X, An Z, Chen H, Huang W.

Organic phosphorescent nanoscintillator for low-dose X-ray-induced photodynamic therapy.

Nat Commun. 2022;13(1):5091.

 

954. Shi C, Zhang Q, Zeng F, Du C, Nijiati S, Wen X, Yang H, Guo Z, Zhang X, Gao J, Chen X, Zhou Z

Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics

Nat Nanotechnol, in press.

 

953. Wang G, Zhou M, Zang J, Jiang Y, Chen X, Zhu Z, Chen X.

A pilot study of 68 Ga-PSMA-617 PET/CT imaging and 177Lu-EB-PSMA-617 radioligand therapy in patients with adenoid cystic carcinoma.

EJNMMI Res. 2022 Aug 19;12(1):52.

 

952. Wu J, Zhang X, Jia Z, Zhou X, Qi R, Ji H, Sun J, Sun C, Teng Z, Lu G, Chen X.

Combined 18F-FDG and 18F-Alfatide II PET May Predict Luminal B (HER2 Negative) Subtype and Nonluminal Subtype of Invasive Breast Cancer.

Mol Pharm. 2022;19(9):3405-3411.

 

951. Bhatia S, Chen X, Dobrovolskaia M, Lammers T

Cancer Nanomedicine

Nat Rev Cancer, 2022;22:550–556

 

950. Li B, Zhao M, Lin J, Huang P, Chen X

Management of fluorescent organic/inorganic nanohybrids for biomedical applications in the NIR-II region

Chem Soc Rev, 2022;51(18):7692-7714

 

949. Huang Q, Chen X, Meng Q-F, Yue L, Jiang W, Zhao X-Z, Rao L, Chen X, S chen

Microfluidics-Assisted Fluorescence Mapping of DNA Phosphorothioation

Anal Chem, 2022;94(29):10479-10486

 

948. Zhao C, Deng H, Chen X

Harnessing Immune Response Using Reactive Oxygen Species-Generating/Eliminating Inorganic Biomaterials for Disease Treatment

Adv Drug Deliv Rev, 2022;188:114456

 

947. Bai L, Hu Z, Han T, Wang Y, Xu J, Jiang G, Feng X, Sun B, Liu X, Tian R, Sun H, Zhang S, Chen X, Zhu S.

Super-stable cyanine@albumin fluorophore for enhanced NIR-II bioimaging

Theranostics. 2022;12(10):4536-4547

 

946. Pan W, Liu L, Rao L, Chen X

Nanomaterial-Mediated Ablation Therapy for Cancer Stem Cells

Matter, 2022;5:1367-1390.

 

945. Kang X, Wang Y, Cai XL, Hua Y, Shao ZH, Chen X, Zhao X, Zang SQ.

Chiral gold clusters functionalized two-dimensional nanoparticle films to regulate the adhesion and differentiation of stem cells

J Colloid Interface Sci. 2022;625:831-838.

 

944. Wang Z, Sun C, Yang K, Chen X, Wang R.

Cucurbituril-based Supramolecular Polymers for Biomedical Applications

Angew Chem Int Ed Engl. 2022;61(38):e202206763.

 

943. Huang P, Deng H, Zhou Y, Chen X

The Roles of Polymers in mRNA Delivery

Matter, 2022;5:1670-1699.

 

942. Wang Y, Hua Y, Shao ZH, Chen X, Zhao X, Zang SQ.

Levonorgestrel-protected Au8 and Au10 clusters with different antimicrobial abilities

J Mater Chem B. 2022;10(26):5028-5034.

 

941. Hua Y, Huang JH, Shao ZH, Luo XM, Wang ZY, Liu JQ, Zhao X, Chen X, Zang SQ.

Composition-Dependent Enzyme Mimicking Activity and Radiosensitizing Effect of Bimetallic Clusters to Modulate Tumor Hypoxia for Enhanced Cancer Therapy

Adv Mater. 2022:e2203734.

 

940. Wen X, Zeng X, Cheng X, Zeng X, Liu J, Zhang Y, Li Y, Chen H, Huang J, Guo Z, Chen X, Zhang X.

PD-L1-Targeted Radionuclide Therapy Combined with αPD-L1 Antibody Immunotherapy Synergistically Improves the Antitumor Effect

Mol Pharm. 2022;19(10):3612-3622.

 

939. Meng L, Fang J, Zhao L, Wang T, Yuan P, Zhao Z, Zhuang R, Lin Q, Chen H, Chen X, Zhang X, Guo Z.

Rational Design and Pharmacomodulation of Protein-Binding Theranostic Radioligands for Targeting the Fibroblast Activation Protein

J Med Chem. 2022;65(12):8245-8257.

 

938. Tian R, Feng X, Wei L, Dai D, Ma Y, Pan H, Ge S, Bai L, Ke C, Liu Y, Lang L, Zhu S, Sun H, Yu Y, Chen X.

A genetic engineering strategy for editing near-infrared-II fluorophores.

Nat Commun. 2022;13(1):2853.

 

937. Mu J, Li C, Shi Y, Liu G, Zou J, Zhang D, Jiang C, Wang X, He L, Huang P, Yin Y, Chen X

Protective Effect of Platinum Nano-antioxidant and Nitric Oxide Against Hepatic Ischemia-Reperfusion Injury

Nat Commun, 2022;13(1):2513

 

936. Zhang Z, Dalan R, Hu Z, Wang JW, Chew NW, Poh KK, Tan RS, Soong TW, Dai Y, Ye L, Chen X.

Reactive Oxygen Species Scavenging Nanomedicine for The Treatment of Ischemic Heart Disease

Adv Mater. 2022:e2202169.

 

935. Huang X, Zha F, Zou J, Li Y, Wang F, Chen X

Photoacoustic Imaging-Guided Synergistic Photothermal/Radiotherapy Using Plasmonic Bi/Bi2O3-x Nanoparticles

Adv Funct Mater, https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.202113353

 

934. Li Q, Xu R, Fan H, Xu J, Xu Y, Cao P, Zhang Y, Liang T, Zhang Y, Chen W, Wang Z, Wang L, Chen X

Smart Mushroom-Inspired Imprintable and Lightly Detachable (MILD) Microneedle Patterns for Effective COVID-19 Vaccination and Decentralized Information Storage

ACS Nano. 2022;16(5):7512–7524.

 

933. Liu C, Liu X, Xiang X, Pang X, Chen S, Zhang Y, Ren E, Zhang L, Liu X, Lv P, Wang X, Luo W, Xia N, Chen X, Liu G

A nanovaccine for antigen self-presentation and immunosuppression reversal as a personalized cancer immunotherapy strategy

Nat Nanotechnol. 2022;17(5):531-540.

 

932. Duan H, Ma T, Huang X, Gao B, Zheng L, Chen X, Xiong Y, Chen X

Avoiding the self-nucleation interference: a pH-regulated gold in situ growth strategy to enable ultrasensitive immunochromatographic diagnostics

Theranostics. 2022;12(6):2801-2810.

 

931. Zhang M, Ye J, Xie Z, Wang Y, Ma W, Kang F, Yang W, Wang J, Chen X

Combined Probe Strategy to Increase the Enzymatic Digestion Rate and Accelerate the Renal Radioactivity Clearance of Peptide Radiotracers

Mol Pharm. 2022;19(5):1548-1556.

 

930. Wen X, Shi C, Zeng X, Zhao L, Yao L, Liu Z, Feng L, Zhang D, Huang J, Li Y, Lin Q, Chen H, Zhuang R, Chen X, Zhang X, Guo Z.

A paradigm of cancer immunotherapy based on 2-[18F]FDG and anti-PD-L1 mAb combination to enhance the anti-tumor effect

Clin Cancer Res. 2022;28(13):2923-2937.

 

929. Li L, Chen X, Yu J, Yuan S.

Preliminary Clinical Application of RGD-Containing Peptides as PET Radiotracers for Imaging Tumors

Front Oncol. 2022;12:837952.

 

928. Lu Y, Feng J, Liang Z, Lu X, Guo S, Huang L, Xiong W, Chen S, Zhou H, Ma X, Xu Y, Qiu X, Wu A, Chen X, Shen Z.

A tumor microenvironment dual responsive contrast agent for contrary contrast-magnetic resonance imaging and specific chemotherapy of tumors

Nanoscale Horiz. 2022;7(4):403-413.

 

927. He P, Ren E, Chen B, Chen H, Cheng H, Gao X, Liang X, Liu H, Li J, Li B, Chen A, Chu C, Chen X, Mao J, Zhang Y, Liu G.

A super-stable homogeneous Lipiodol-hydrophilic chemodrug formulation for treatment of hepatocellular carcinoma

Theranostics. 2022;12(4):1769-1782.

 

926. Xue Y, Che J, Ji X, Li Y, Xie J, Chen X.

Recent advances in biomaterial-boosted adoptive cell therapy

Chem Soc Rev. 2022;51(5):1766-1794.

 

925. Li B, Liu H, He Y, Zhao M, Ge C, Younis MR, Huang P, Chen X, Lin J.

A "Self-Checking" pH/Viscosity-Activatable NIR-II Molecule for Real-Time Evaluation of Photothermal Therapy Efficacy

Angew Chem Int Ed Engl. 2022;61(16):e202200025.

 

924. Wu SY, Wu FG, Chen X.

Antibody-Incorporated Nanomedicines for Cancer Therapy

Adv Mater. 2022;34(24):e2109210.

 

923. Wu J, Tian J, Zhang Y, Ji H, Sun J, Wang X, Sun C, Wang L, Teng Z, Lu G, Zhu H, Chen X.

18F-Alfatide II for the evaluation of axillary lymph nodes in breast cancer patients: comparison with 18F-FDG

Eur J Nucl Med Mol Imaging. 2022;49(8):2869-2876.

 

922. Qiu Q, Huang Y, Zhang B, Huang D, Chen X, Fan Z, Lin J, Yang W, Wang K, Qu N, Li J, Li Z, Huang J, Li S, Zhang J, Liu G, Rui G, Chen X, Zhao Q

Noninvasive Dual-Modality Photoacoustic-Ultrasonic Imaging to Detect Mammalian Embryo Abnormalities after Prenatal Exposure to Methylmercury Chloride (MMC): A Mouse Study

Environ Health Perspect. 2022;130(2):27002.

 

921. Hou L, Gongu X, Zhang JH, Yang W, Chen X

Hybrid Membrane-Decorated Prussian Blue for Effective Cancer Immunotherapy via Tumor-Associated Macrophages Polarization and Hypoxia Relief

Adv Mater. 2022;34(14):e2200389.

 

920. Wu D, Yang K, Zhang Z, Feng Y, Rao L, Chen X, Yu G.

Metal-free bioorthogonal click chemistry in cancer theranostics

Chem Soc Rev. 2022;51(4):1336-1376.

 

919. Wen X, Xu P, Shi M, Liu J, Zeng X, Zhang Y, Shi C, Li J, Guo Z, Zhang X, Khong PL, Chen X.

Evans blue-modified radiolabeled fibroblast activation protein inhibitor as long-acting cancer therapeutics

Theranostics. 2022;12(1):422-433.

 

918. Li B, Lin J, Huang P, Chen X.

Near-infrared probes for luminescence lifetime imaging

Nanotheranostics. 2022;6(1):91-102.

 

917. Zeng F, Tang L, Zhang Q, Shi C, Huang Z, Nijiati S, Chen X, Zhou Z.

Coordinating the mechanism of actions of ferroptosis and photothermal effect for cancer theranostics

Angew Chem Int Ed Engl. 2022;61(13):e202112925.

 

916. Ma Y, Su Z, Zhou L, He L, Hou Z, Zou J, Cai Y, Chang D, Xie J, Zhu C, Fan W, Chen X, Ju S.

Biodegradable Metal-Organic Framework-Gated Organosilica for Tumor Microenvironment-Unlocked Glutathione Depletion-Enhanced Synergistic Therapy

Adv Mater. 2022;34(12):e2107560.

 

915. Schuchardt C, Zhang J, Kulkarni HR, Chen X, Mueller D, Baum RP.

Prostate-specific membrane antigen radioligand therapy using 177Lu-PSMA I&T and 177Lu-PSMA-617 in patients with metastatic castration-resistant prostate cancer: comparison of safety, biodistribution and dosimetry

J Nucl Med. 2022;63(8):1199-1207.

 

914. Mu J, Xiao M, Shi Y, Geng X, Li H, Yin Y, Chen X.

The Chemistry of Organic Contrast Agents in the NIR-II Window

Angew Chem Int Ed Engl. 2022;61(14):e202114722.

 

913. Zhao C, Pang X, Yang Z, Wang S, Deng H, Chen X.

Nanomaterials targeting tumor associated macrophages for cancer immunotherapy

J Control Release. 2022;341:272-284.

 

912. Cui C, Wang C, Fu Q, Song J, Zou J, Li L, Zhu J, Huang W, Li L, Yang Z, Chen X.

A generic self-assembly approach towards phototheranostics for NIR-II fluorescence imaging and phototherapy

Acta Biomater. 2022;140:601-609.

911. Hua Y, Wang Y, Kang X, Xu F, Han Z, Zhang C, Wang ZY, Liu JQ, Zhao X, Chen X, Zang SQ.

A multifunctional AIE gold cluster-based theranostic system: tumor-targeted imaging and Fenton reaction-assisted enhanced radiotherapy

J Nanobiotechnology. 2021;19(1):438.

 

910. Shi X, Zhang Y, Tian Y, Xu S, Ren E, Bai S, Chen X, Chu C, Xu Z, Liu G.

Multi-Responsive Bottlebrush-Like Unimolecules Self-Assembled Nano-Riceball for Synergistic Sono-Chemotherapy

Small Methods. 2021;5(3):e2000416.

 

909. Lin H, Zhou Y, Wang J, Wang H, Yao T, Chen H, Zheng H, Zhang Y, Ren E, Jiang L, Chu C, Chen X, Mao J, Wang F, Liu G.

Repurposing ICG enables MR/PA imaging signal amplification and iron depletion for iron-overload disorders

Sci Adv. 2021;7(51):eabl5862.

 

908. Jia R, Xu H, Wang C, Su L, Jing J, Xu S, Zhou Y, Sun W, Song J, Chen X, Chen H.

NIR-II emissive AIEgen photosensitizers enable ultrasensitive imaging-guided surgery and phototherapy to fully inhibit orthotopic hepatic tumors

J Nanobiotechnology. 2021;19(1):419.

 

907. Li J, Dai S, Qin R, Shi C, Ming J, Zeng X, Wen X, Zhuang R, Chen X, Guo Z, Zhang X.

Ligand Engineering of Titanium-Oxo Nanoclusters for Cerenkov Radiation-Reinforced Photo/Chemodynamic Tumor Therapy

ACS Appl Mater Interfaces. 2021;13(46):54727-54738.

 

906. Liu K, Kang B, Luo X, Yang Z, Sun C, Li A, Fan Y, Chen X, Gao J, Lin H.

Redox-Activated Contrast-Enhanced T1-Weighted Imaging Visualizes Glutathione-Mediated Biotransformation Dynamics in the Liver

ACS Nano. 2021;15:17831-17841.

 

905. Mo T, Liu X, Luo Y, Zhong L, Zhang Z, Li T, Gan L, Liu X, Li L, Wang H, Sun X, Fan D, Qian Z, Wu P, Chen X.

Aptamer-based biosensors and application in tumor theranostics

Cancer Sci. 2022;113:7-16.

 

904. Huang L, Feng J, Fan W, Tang W, Rong X, Liao W, Wei Z, Xu Y, Wu A, Chen X, Shen Z.

Intelligent Pore Switch of Hollow Mesoporous Organosilica Nanoparticles for High Contrast Magnetic Resonance Imaging and Tumor-Specific Chemotherapy

Nano Lett. 2021;21(22):9551-9559.

 

903. Yang K, Yang Z, Yu G, Nie Z, Wang R, Chen X.

Polyprodrug Nanomedicines: An Emerging Paradigm for Cancer Therapy

Adv Mater. 2022;34(6):e2107434.

 

902. Zhao L, Pang Y, Wang Y, Chen J, Zhuang Y, Zhang J, Zhao L, Sun L, Wu H, Chen X, Lin Q, Chen H.

Somatostatin receptor imaging with [68Ga]Ga-DOTATATE positron emission tomography/computed tomography (PET/CT) in patients with nasopharyngeal carcinoma

Eur J Nucl Med Mol Imaging. 2022;49(4):1360-1373.

 

901. Meng QF, Zhao Y, Dong C, Liu L, Pan Y, Lai J, Liu Z, Yu GT, Chen X, Rao L.

Genetically Programmable Fusion Cellular Vesicles for Cancer Immunotherapy

Angew Chem Int Ed Engl. 2021;60(50):26320-26326.

 

900. Chen W, Wang Z, Wang L, Chen X.

Smart Chemical Engineering-based Lightweight and Miniaturized Attachable Systems for Advanced Drug Delivery and Diagnostics

Adv Mater. 2022;34(6):e2106701.

 

899. Xu D, Lin X, Zeng X, Wen X, Li J, Li Y, Huang J, Chen X, Guo Z, Zhang X.

Radioiodinated 4-(p-Iodophenyl) Butanoic Acid-Modified Estradiol Derivative for ER Targeting SPECT Imaging

Anal Chem. 2021;93(41):13998-14006.

 

898. Lin X, He J, Li W, Qi Y, Hu H, Zhang D, Xu F, Chen X, Zhou M.

Lung-Targeting Lysostaphin Microspheres for Methicillin-Resistant Staphylococcus aureus Pneumonia Treatment and Prevention

ACS Nano. 2021;15(10):16625-16641.

 

897. Zhou Y, Fan S, Feng L, Huang X, Chen X.

Manipulating Intratumoral Fenton Chemistry for Enhanced Chemodynamic and Chemodynamic-Synergized Multimodal Therapy

Adv Mater. 2021;33(48):e2104223.

 

896. Zou J, Li L, Zhu J, Li X, Yang Z, Huang W, Chen X.

Singlet Oxygen "Afterglow" Therapy with NIR-II Fluorescent Molecules

Adv Mater. 2021;33(44):e2103627.

 

895. Zhang M, Ye J, Xie Z, Yan Y, Wang J, Chen X.

Optimization of Enzymolysis Clearance Strategy To Enhance Renal Clearance of Radioligands

Bioconjug Chem. 2021;32(9):2108-2116.

 

894. Fan W, Song M, Li L, Niu L, Chen Y, Han B, Sun X, Yang Z, Lei Y, Chen X.

Endogenous dual stimuli-activated NO generation in the conventional outflow pathway for precision glaucoma therapy

Biomaterials. 2021;277:121074.

 

893. Tong L, Hao H, Zhang Z, Lv Y, Liang X, Liu Q, Liu T, Gong P, Zhang L, Cao F, Pastorin G, Lee CN, Chen X, Wang JW, Yi H.

Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota

Theranostics. 2021;11(17):8570-8586.

 

892. Wang S, Ren WX, Hou JT, Won M, An J, Chen X, Shu J, Kim JS.

Fluorescence imaging of pathophysiological microenvironments.

Chem Soc Rev. 2021;50(16):8887-8902.

 

891. Zhou Z, Du C, Zhang Q, Yu G, Zhang F, Chen X.

Exquisite vesicular nanomedicine by paclitaxel mediated co-assembly with camptothecin prodrug. Angew Chem Int Ed Engl. 2021;60(38):21033-21039.

 

890. Jiang Z, He L, Yu X, Yang Z, Wu W, Wang X, Mao R, Cui D, Chen X, Li W.

Antiangiogenesis Combined with Inhibition of the Hypoxia Pathway Facilitates Low-Dose, X-ray-Induced Photodynamic Therapy

ACS Nano. 2021;15(7):11112-11125.

 

889. Huang D, Wang G, Mao J, Liu C, Fan Z, Zhang Y, Zhang B, Zhao Y, Dai C, He Y, Ma H, Liu G, Chen X, Zhao Q.

Intravital Whole-Process Monitoring Thermo-Chemotherapy Via 2D Silicon Nanoplatform: A Macro Guidance and Long-Term Microscopic Precise Imaging Strategy

Adv Sci (Weinh). 2021;8(16):e2101242.

 

888. Ding D, Feng Y, Qin R, Li S, Chen L, Jing J, Zhang C, Sun W, Li Y, Chen X, Chen H.

Mn3+-rich oxide/persistent luminescence nanoparticles achieve light-free generation of singlet oxygen and hydroxyl radicals for responsive imaging and tumor treatment

Theranostics. 2021;11(15):7439-7449.

 

887. Liu X, Wu W, Cui D, Chen X, Li W.

Functional Micro-/Nanomaterials for Multiplexed Biodetection

Adv Mater. 2021;33(30):e2004734.

 

886. Hou G, Jiang Y, Xu W, Zhu Z, Huo L, Chen X, Li F, Xu KF, Cheng W.

68Ga-NOTA-Evans Blue PET/CT findings in lymphangioleiomyomatosis compared with 99mTC-ASC lymphoscintigraphy: a prospective study.

Orphanet J Rare Dis. 2021;16(1):279

 

885. Ding C, Huang Y, Shen Z, Chen X

Synthesis and Bioapplications of Ag2S Quantum Dots with Near-Infrared Fluorescence

Adv Mater. 2021;33(32):e2007768.

 

884. Zhu X, Tang X, Lin H, Shi S, Xiong H, Zhou Q, Li A, Wang Q, Chen X, Gao J.

A Fluorinated Ionic Liquid-Based Activatable 19F MRI Platform Detects Biological Targets

Chem. 2020;6(5):1134-1148.

 

883. Yang K, Yue L, Yu G, Rao L, Tian R, Wei J, Yang Z, Sun C, Zhang X, Xu M, Yuan Z, Chen X, Wang R.

A hypoxia responsive nanoassembly for tumor specific oxygenation and enhanced sonodynamic therapy

Biomaterials. 2021;275:120822.

 

882. Yang K, Yang Z, Yue L, Yu G, Zhang X, Sun C, Wei J, Rao L, Chen X, Wang R.

Supramolecular Polymerization-Induced Nanoassemblies for Self-Augmented Cascade Chemotherapy and Chemodynamic Therapy of Tumour

Angew Chem Int Ed Engl. 2021;60(32):17570-17578.

 

881. Wang S, Yu G, Yang W, Wang Z, Jacobson O, Tian R, Deng H, Lin L, Chen X.

Photodynamic-Chemodynamic Cascade Reactions for Efficient Drug Delivery and Enhanced Combination Therapy

Adv Sci (Weinh). 2021;8(10):2002927.

 

880. Escudé Martinez de Castilla P, Tong L, Huang C, Marios Sofias A, Pastorin G, Chen X, Storm G, Schiffelers RM, Wang JW.

Extracellular vesicles as a drug delivery system: A systematic review of preclinical studies

Adv Drug Deliv Rev. 2021;175:113801.

 

879. Wang S, Tian R, Zhang X, Cheng G, Yu P, Chang J, Chen X.

Beyond Photo: Xdynamic Therapies in Fighting Cancer.

Adv Mater. 2021:e2007488.

 

878. Kim J, Kim JS, Min KH, Kim YH, Chen X

Bombesin-Tethered Reactive Oxygen Species (ROS)-Responsive Nanoparticles for Monomethyl Auristatin F (MMAF) Delivery

Bioengineering (Basel). 2021 Mar 29;8(4):43.

 

877. Meng QF, Tian R, Long H, Wu X, Lai J, Zharkova O, Wang JW, Chen X, Rao L.

Capturing Cytokines with Advanced Materials: A Potential Strategy to Tackle COVID-19 Cytokine Storm

Adv Mater. 2021 Apr 10:e2100012. doi: 10.1002/adma.202100012.

 

876. Chen T, Hou P, Zhang Y, Ao R, Su L, Jiang Y, Zhang Y, Cai H, Wang J, Chen Q, Song J, Lin L, Yang H, Chen X.

Singlet Oxygen Generation in Dark-Hypoxia by Catalytic Microenvironment-Tailored Nanoreactors for NIR-II Fluorescence-Monitored Chemodynamic Therapy

Angew Chem Int Ed Engl. 2021;60(27):15006-15012.

 

875. Guo Y, Sun Q, Wu FG, Dai Y, Chen X.

Polyphenol-Containing Nanoparticles: Synthesis, Properties, and Therapeutic Delivery

Adv Mater. 2021 Apr 19:e2007356.

 

874. He L, Mu J, Gang O, Chen X.

Rationally Programming Nanomaterials with DNA for Biomedical Applications

Adv Sci (Weinh). 2021 Feb 24;8(8):2003775.

 

873. Cheng Y, Jiao X, Wang Z, Jacobson O, Aronova MA, Ma Y, He L, Liu Y, Tang W, Deng L, Zou J, Yang Z, Zhang M, Wen Y, Fan W, Chen X

Biphasic synthesis of biodegradable urchin-like mesoporous organosilica nanoparticles for enhanced cellular internalization and precision cascaded therapy

Biomater Sci. 2021;9:2584-2597.

 

872. Ji Q, Hou J, Yong X, Gong G, Muddassir M, Tang T, Xie J, Fan W, Chen X

Targeted Dual Small Interfering Ribonucleic Acid Delivery via Non-Viral Polymeric Vectors for Pulmonary Fibrosis Therapy

Adv Mater. 2021:e2007798.

 

871. Zhou J, Rao L, Yu G, Cook TR, Chen X, Huang F.

Supramolecular cancer nanotheranostics.

Chem Soc Rev. 2021;50(4):2839-2891.

 

870. Yu X, Liu X, Yang K, Chen X, Li W.

Pnictogen Semimetal (Sb, Bi)-Based Nanomaterials for Cancer Imaging and Therapy: A Materials Perspective

ACS Nano. 2021;15(2):2038-2067.

 

869. Tang W, Yang Z, He L, Deng L, Fathi P, Zhu S, Li L, Shen B, Wang Z, Jacobson O, Song J, Zou J, Hu P, Wang M, Mu J, Cheng Y, Ma Y, Tang L, Fan W, Chen X

A hybrid semiconducting organosilica-based O2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy

Nat Commun. 2021;12(1):523.

 

868. Thakur S, Daley B, Millo C, Cochran C, Jacobson O, Lu H, Wang Z, Kiesewetter D, Chen X, Vasko V, Klubo-Gwiezdzinska J.

177Lu-DOTA-EB-TATE, a Radiolabeled Analogue of Somatostatin Receptor Type 2, for the Imaging and Treatment of Thyroid Cancer

Clin Cancer Res. 2021;27(5):1399-1409.

 

867. Fu Q, Li Z, Fu F, Chen X, Song J, Yang H.

Stimuli-Responsive Plasmonic Assemblies and Their Biomedical Applications.

Nano Today. 2021;36:101014.

 

866. Luo Y, Chen X

Imaging of Insulinoma by Targeting Glucagonlike Peptide-1 Receptor.

PET Clin. 2021 Feb 12:S1556-8598(20)30103-6.

865. He K, Chi C, Li D, Zhang J, Niu G, Lv F, Wang J, Che W, Zhang L, Ji N, Zhu Z, Tian J, Chen X.

Resection and survival data from a clinical trial of glioblastoma multiforme-specific IRDye800-BBN fluorescence-guided surgery.

Bioeng Transl Med. 2020;6(1):e10182.

 

864. Yu G, Jiang M, Huang F, Chen X

Supramolecular coordination complexes as diagnostic and therapeutic agents.

Curr Opin Chem Biol. 2020;61:19-31.

 

863. Jiang M, Mu J, Jacobson O, Wang Z, He L, Zhang F, Yang W, Lin Q, Zhou Z, Ma Y, Lin J, Qu J, Huang P, Chen X

Reactive Oxygen Species Activatable Heterodimeric Prodrug as Tumor-Selective Nanotheranostics.

ACS Nano. 2020; 14: 16875–16886

 

862. Novelli EM, Moon CH, Pham TA, Perkins LA, Little-Ihrig L, Tavakoli S, Mason NS, Lang L, Chen X, Laymon CM, Gladwin MT, Anderson CJ.

First report of 68Ga-PRGD2 PET/MRI molecular imaging of vaso-occlusion in a patient with sickle cell disease.

BJR Case Rep. 2020;6(4):20200024.

 

861. Zhang Y, Wang X, Chu C, Zhou Z, Chen B, Pang X, Lin G, Lin H, Guo Y, Ren E, Lv P, Shi Y, Zheng Q, Yan X, Chen X, Liu G.

Genetically engineered magnetic nanocages for cancer magneto-catalytic theranostics

Nat Commun. 2020;11(1):5421.

 

860. Yang W, Deng H, Zhu S, Lau J, Tian R, Wang S, Zhou Z, Yu G, Rao L, He L, Ma Y, Chen X

Size-Transformable Antigen-Presenting Cell Mimicking Nanovesicles for Effective Cancer Immunotherapy

Sci Adv, 2020;6(50):eabd1631.

 

859. Deng H, Yang W, Zhou Z, Tian R, Lin L, Ma Y, Song J, Chen X

Targeted Scavenging of Extracellular ROS Relieves Suppressive Immunogenic Cell Death

Nat Commun, 2020;11(1):4951.

 

858. Chen XS, Moon JJ, Cheon J.

New Opportunities in Cancer Immunotherapy and Theranostics.

Acc Chem Res. 2020;53(12):2763-2764.

 

857. Zhang X, Wang S, Cheng G, Yu P, Chang J, Chen X

Cascade Drug Release Strategy for Enhanced Anticancer Therapy

Matter, 2021; 4: 26-53

 

856. Rao L, Zhao S-K, Wen C, Tian R, Lin L, Cai B, Sun Y, Kang F, Yang Z, He L, Mu J, Meng Q-F, Yao G, Xie N, Chen X

Activating Macrophage-Mediated Cancer Immunotherapy by Genetically Edited Nanoparticles

Adv Mater, 2020;32:2004853

 

855. Rao L, Xia S, Xu W, Tian R, Yu G, Gu C, Pan P, Meng Q-F, Cai X, Qu D, Lu L, Xie Y, Jiang S, Chen X

Decoy nanoparticles protect against COVID-19 by concurrently adsorbing viruses and inflammatory cytokines

PNAS, 2020:202014352. [cover story, highlighted by the Scientist]

 

854. Chen W, Cai B, Cheng Z, Chen F, Wang Z, Wang L, Chen X

Reducing false negatives in COVID-19 testing by using microneedle-based oropharyngeal swabs

Matter, 2020;3(5):1589-1600. [Cover]

 

853. Liu Q, Zang J, Sui H, Ren J, Guo H, Wang H, Wang R, Jacobson O, Zhang J, Cheng Y, Zhu Z, Chen X.

Peptide Receptor Radionuclide Therapy of Late-stage Neuroendocrine Tumor Patients with Multiple Cycles of 177Lu-DOTA-EB-TATE

J Nucl Med. 2020 Aug 21:jnumed.120.248658. doi: 10.2967/jnumed.120.248658.

 

852. Zhao L, Chen H, Guo Z, Fu K, Yao L, Fu L, Guo W, Wen X, Jacobson O, Zhang X, Sun L, Wu H, Lin Q, Chen X.

Targeted radionuclide therapy in patient-derived xenografts using 177Lu-EB-RGD

Mol Cancer Ther. 2020; 19(10): 2034-2043.

 

851. Li L, Yang Z, Chen X.

Recent Advances in Stimuli-Responsive Platforms for Cancer Immunotherapy

Acc Chem Res. 2020; 53(10): 2044-2054.

 

850. Wu D, Wang S, Yu G, Chen X.

Cell Death Mediated by Pyroptosis Pathway with the Help of Nanotechnology: New Prospects for Cancer Therapy

Angew Chem Int Ed Engl. 2020 Sep 7. doi: 10.1002/anie.202010281.

 

849. Jiang Y, Wang Z, Duan W, Liu L, Si M, Chen X, Fang CJ

The critical size of gold nanoparticles for overcoming P-gp mediated multidrug resistance

Nanoscale. 2020;12(31):16451-16461.

 

848. Lin L, Wang S, Deng H, Yang W, Rao L, Tian R, Liu Y, Yu G, Zhou Z, Song J, Yang HH, Chen ZY, Chen X

Endogenous Labile Iron Pool-Mediated Free Radical Generation for Cancer Chemodynamic Therapy

J Am Chem Soc. 2020; 142(36): 15320-15330.

 

847. Rao L, Wu L, Liu Z, Tian R, Yu G, Zhou Z, Yang K, Xiong HG, Zhang A, Yu GT, Li A, Chen H, Sun ZJ, Fu YX, Chen X

Designer cell membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis

Nat Commun, 2020;11(1):4909.

 

846. Lin Q, Fathi P, Chen X

Nanoparticle delivery in vivo: a fresh look from an intravital imaging perspective

EBioMedicine, 2020;59:102958

 

845. Mu J, He L, Fan W, Tang W, Wang Z, Jiang C, Zhang D, Liu Y, Deng H, Zou J, Jacobson O, Qu J, Huang P, Chen X

Cascade Reactions Catalyzed by Planar Metal Organic Framework Hybrid Architecture for Combined Cancer Therapy

Small, 2020;e2004016.

 

844. Chu C, Yu J, Ren E, Ou S, Zhang Y, Wu Y, Wu H, Zhang Y, Zhu J, Dai Q, Wang X, Zhao Q, Li W, Liu Z, Chen X, Liu G

Multimodal Photoacoustic Imaging-Guided Regression of Corneal Neovascularization: A Non-Invasive and Safe Strategy

Adv Sci (Weinh). 2020;7(14):2000346. doi: 10.1002/advs.202000346.

 

843. He G, Huang P, Chen X

Theranostic multimodal gold nanoclusters

Nat Biomed Eng. 2020;4(7):668-669.

 

842. Tang L, Wang Z, Mu Q, Yu Z, Jacobson O, Li L, Yang W, Huang C, Kang F, Fan W, Ma Y, Wang S, Zhou Z, Chen X

Targeting Neutrophils for Enhanced Cancer Theranostics

Adv Mater, 2020; 32: 2002739

 

841. Liu W, Wu J, Ji X, Ma Y, Liu L, Zong X, Yang H, Dai J, Chen X, Xue W

Advanced biomimetic nanoreactor for specifically killing tumor cells through multi-enzyme cascade

Theranostics. 2020;10(14):6245-6260.

 

840. Wang S, Zhang F, Yu G, Wang Z, Jacobson O, Ma Y, Tian R, Deng H, Yang W, Chen ZY, Chen X

Zwitterionic-to-cationic charge conversion polyprodrug nanomedicine for enhanced drug delivery

Theranostics. 2020;10(15):6629-6637.

 

839. Zhou Z, Ni K, Deng H, Chen X

Dancing with reactive oxygen species generation and elimination in nanotheranostics for disease treatment

Adv Drug Deliv Rev. 2020; 158: 73-90.

 

838. Chen X, Chen M.

Critical reviews of immunotheranostics

Theranostics. 2020;10(16):7403-7405.

 

837. Xu MM, Jia TT, Li B, Ma W, Chen X, Zhao X, Zang SQ

Tuning the properties of atomically precise gold nanoclusters for biolabeling and drug delivery

Chem Commun (Camb). 2020; 56(62): 8766-8769.

 

836. Xia Y, Rao L, Yao H, Wang Z, Ning P, Chen X

Engineering macrophages for cancer immunotherapy and drug delivery

Adv Mater, 2020;32(40):e2002054.

 

835. Cheng Y, Jiao X, Fan W, Yang Z, Wen Y, Chen X

Controllable Synthesis of Versatile Mesoporous Organosilica Nanoparticles as Precision Cancer Theranostics

Biomaterials, 2020;256:120191

 

834. Lau J, Rousseau E, Kwon D, Lin K-S, Bernard F, Chen X

Insight into the Development of PET Radiopharmaceuticals for Oncology

Cancers, 2020;12(5):1312

 

833. Liu T, Xiao B, Xiang F, Tan J, Chen Z, Wu C, Mao Z, Luo G, Chen X, Deng J

Ultrasmall Copper-Based Nanoparticles for Reactive Oxygen Species Scavenging and Alleviation of Inflammation Related Diseases

Nat Commun, 2020;11(1):2788

 

832. Lin H, Li S, Wang J, Chu C, Zhang Y, Pang X, Lv P, Wang X, Zhao Q, Chen J, Chen H, Liu W, Chen X, Liu G

A single-step multi-level supramolecular system for cancer sonotheranostics

Nanoscale Horiz. 2019;4(1):190-195.

 

831. Zhang W, Chen T, Su L, Ge X, Chen X, Song J, Yang H

Quantum Dot-Based Sensitization System for Boosted Photon Absorption and Enhanced Second Near-Infrared Luminescence of Lanthanide-Doped Nanoparticle

Anal Chem, 2020; 92(8): 6094-6102.

 

830. Zhou Z, Deng H, Yang W, Wang Z, Lin L, Munasinghe J, Jacobson O, Liu Y, Tang L, Ni Q, Kang F, Liu Y, Niu G, Bai R, Qian C, Song J, Chen X

Early stratification of radiotherapy response by activatable inflammation magnetic resonance imaging

Nat Commun, 2020;11(1):3032  

 

829. Zang J, Liu Q, Sui H, Wang R, Jacobson O, Fan X, Zhu Z, Chen X

177Lu-EB-PSMA radioligand therapy with escalating doses in patients with metastatic castration-resistant prostate cancer

J Nucl Med, 2020; 61(12):1772-1778.

 

828. Sun W, Luo L, Feng Y, Qiu Y, Meng S, Chen X, Chen H

Gadolinium-Rose Bengal Coordinated Polymer Nanodots for MR/Fluorescence ImageGuided Radiation and Photodynamic Therapy

Adv Mater, 2020;32(23):e2000377.

 

827. Zhu R, Su L, Dai J, Li ZW, Bai S, Li Q, Chen X, Song J, Yang H

Biologically Responsive Plasmonic Assemblies for Second Near-Infrared Window Photoacoustic Imaging-Guided Concurrent Chem-Immunotherapy

ACS Nano, 2020; 14(4): 3991-4006.

 

826. Shao T, Chen Z, Belov V, Wang X, Rwema SH, Kumar V, Fu H, Deng X, Rong J, Yu Q, Lang L, Lin W, Josephson L, Samir AE, Chen X, Chung RT, Liang SH.

 [18F]- Alfatide PET imaging of integrin αvβ3 for the non-invasive quantification of liver fibrosis

J Hepatol. 2020;73(1):161-169.

 

825. Liu D, Zhou Z, Wang X, Deng H, Kang F, Zhang Y, Wang Z, Yang W, Rao L, Yang K, Yu G, Du J, Shen Z, Chen X

Yolk-shell nanovesicles endow glutathione-responsive concurrent drug release and T1 MRI activation for cancer theranostics

Biomaterials, 2020; 244: 119979

 

824. Zhao X, Zang S, Chen X

Stereospecific Interactions between Chiral Nanomaterials and Biological Systems

Chem Soc Rev, 2020; 49: 2481-2503

 

823. He L, Ni Q, Mu J, Fan W, Liu L, Wang Z, Li L, Tang W, Liu Y, Cheng Y, Tang L, Yang Z, Liu Y, Zou J, Yang W, Jacobson O, Zhang F, Huang P, Chen X

Solvent-assisted self-assembly of metal-organic framework-based biocatalyst for cascade reactions-driven photodynamic therapy

J Am Chem Soc, 2020; 142(14): 6822-6832.

 

822. Shi T, Sun W, Qin R, Li D, Feng Y, Chen L, Liu G, Chen X, Chen H

X-ray-Induced Persistent Luminescence Promotes Ultrasensitive Imaging and Effective Inhibition of Orthotopic Hepatic Tumors

Adv Funct Mater, 2020, 2001166  

 

821. Klubo-Gwiezdzinska J, Chen X.

Targeting Integrins with Radiolabeled RGD Analogs for Radiotheranostics of Metastatic Radioactive Iodine Non-Responsive Thyroid Cancer - New Avenues in Personalized Medicine

Thyroid. 2020; 30(4): 476-478.

 

820. Xie L, Pang X, Yan X, Lin H, Ye J, Cheng Y, Dai Q, Zhao Q, Zhang X, Liu G, Chen X

Photoacoustic Imaging-Trackable Magnetic Microswimmers for Pathogenic Bacterial Infection Treatment

ACS Nano, 2020; 14(3): 2880-2893.

 

819. Rao L, Tian R, Chen X

Cell Membrane Mimicking Nanodecoys Against Infectious Diseases

ACS Nano, 2020; 14(3): 2569-2574.

 

818. Luo L, Sun W, Feng Y, Qin R, Zhang J, Ding D, Shi T, Liu X, Chen X, Chen H

Conjugation of a Scintillator Complex and Gold Nanorods for Dual-Modal Image-Guided Photothermal and X-RayInduced Photodynamic Therapy of Tumors

ACS Appl Mater Interfaces, 2020; 12(11): 12591-12599.

 

817. Deng H, Zhou Z, Yang W, Lin L-S, Wang S, Niu G, Song J, Chen X

Endoplasmic Reticulum Targeting to Amplify Immunogenic Cell Death for Cancer Immunotherapy

Nano Lett, 2020; 20(3): 1928-1933.

 

816. Zhu X, Tang X, Lin H, Shi S, Xiong H, Zhou Q, Li A, Wang Q, Chen X, Gao J

A Fluorinated-Ionic-Liquid-Based Activatable 19F MRI Platform Enables Detection and Imaging of Biological Targets

Chem, 2020;6:1134-1148.

 

815. Hou G, Xu W, Jiang Y, Xu KF, Chen X, Li F, Cheng W

Lymphangioleiomyomatosis revealed by 68Ga-NOTA-Evans Blue PET/CT

Eur J Nucl Med Mol Imaging. 2020; 47(10): 2469-2470.

 

814. Shen Z, Liu T, Yang Z, Zhou Z, Tang W, Fan W, Liu Y, Mu J, Li L, Bregadze VI, Mandal SK, Druzina AA, Wei Z, Qiu X, Wu A, Chen X

Small-sized gadolinium oxide based nanoparticles for high-efficiency theranostics of orthotopic glioblastoma

Biomaterials. 2020;235:119783

 

813. Zou J, Zhu J, Yang Z, Li L, Fan W, He L, Tang W, Deng L, Mu J, Ma Y, Cheng Y, Huang W, Dong X, Chen X

A phototheranostics strategy to continuously deliver singlet oxygen in dark and hypoxic tumor microenvironment

Angew Chem Int Ed Engl. 2020; 59: 1-7.

 

812. Lin X, Song J, Chen X, Yang H.

Ultrasound Activated Sensitizers and Applications

Angew Chem Int Ed Engl. 2020; 59: 2-24

 

811. Li X, Lovell J, Yoon J, Chen X

Current clinical status and potential of photothermal and photodynamic cancer therapy

Nat Rev Clin Oncol, 2020; 17(11): 657-674.

 

810. Li L, Zou J, Dai Y, Fan W, Niu G, Yang Z, Chen X

Burst release of encapsulated annexin A5 in tumours boosts cytotoxic T-cell responses by blocking the phagocytosis of apoptotic cells

Nat Biomed Eng, 2020; 4: 1102-1116.

 

809. Tian R, Ma H, Zhu S, Lau J, Ma R, Liu Y, Lin L, Chandra S, Wang S, Niu G, Zhang M, Antaris AL, Hettie KS, Yang B, Liang Y, Chen X

Multiplexed NIR-II imaging for lymph node-invaded cancer detection and full-process light exposure surgery

Adv Mater, 2020;32:1907365

 

808. Shi Y, Wang J, Liu J, Lin G, Xie F, Pang X, Pei Y, Cheng Y, Zhang Y, Lin Z, Yin Z, Wang X, Niu G, Chen X, Liu G

Oxidative stress-driven DR5 upregulation restores TRAIL/Apo2L sensitivity induced by iron oxide nanoparticles in colorectal cancer

Biomaterials, 2020;233:119753

 

807. Tang X, Gong X, Li A, Lin H, Peng C, Zhang X, Chen X, Gao J.

Cascaded Multiresponsive Self-Assembled 19F MRI Nanoprobes with Redox-Triggered Activation and NIR-Induced Amplification

Nano Lett, 2020;20(1):363-371

 

806. Zang J, Liu Q, Sui H, Guo H, Peng L, Li F, Lang L, Jacobson O, Mao F, Zhu Z, Chen X

Combined 68Ga-NOTA-Evans Blue Lymphoscintigraphy and 68Ga-NOTA-RM26 PET/CT Evaluation of Sentinel Lymph Node Metastasis in Breast Cancer Patients

Bioconjug Chem, 2020; 31(2):396-403.

 

805. Yang W, Zhang F, Deng H, Lin L, Wang S, Kang F, Yu G, Lau J, Tian R, Zhang M, Wang Z, He L, Ma Y, Niu G, Hu S, Chen X

Smart Nanovesicle Mediated Immunogenic Cell Death Through Tumor Microenvironment Modulation for Effective Photodynamic-Immunotherapy

ACS Nano, 2020;14(1):620-631

 

804. Yu Q, Huang S, Wu Z, Zheng J, Chen X, Nie L.

Label-free Visualization of Early Cancer Hepatic Micrometastasis and Intraoperative Image-guided Surgery by Photoacoustic Imaging

J Nucl Med. 2020;61(7):1079-1085.

 

803. Ni Q, Zhang F, Liu Y, Wang Z, Yu G, Liang B, Niu G, Su T, Lu G, Zhu G, Zhang L, Chen X

A bi-adjuvant nanovaccine that potentiates immunogenicity of neoantigen for combination immunotherapy of colorectal cancer

Sci Adv, 2020;6:eaaw6071

 

802. Lin X, Liu S, Zhang X, Zhu R, Chen S, Chen X, Song J, Yang H.

Ultrasound Activated Vesicle of Janus Au-MnO Nanoparticles for Promoted Tumor Penetration and Sono-Chemodynamic Therapy of Orthotopic Liver Cancer

Angew Chem Int Ed Engl. 2020;59(4):1682-1688.

 

801. Sun W, Zhou Z, Pratx G, Chen X, Chen H

Nanoscintillator-mediated X-ray induced photodynamic therapy for deep-seated tumors: from concept to biomedical applications

Theranostics, 2020;10(3):1296-1318.

 

800. Hao L, Leng Y, Zeng L, Chen X, Chen J, Duan H, Huang X, Xiong Y, Chen X

Core–Shell Heterostructured Magnetic–Plasmonic Nanoassemblies with Highly Retained Magnetic–Plasmonic Activities for Ultrasensitive Bioanalysis in Complex Matrix

Adv Sci, 2020;7:1902433

 

799. Huang X, Zhou Y, Ding L, Yu G, Leng Y, Lai W, Xiong Y, Chen X

Supramolecular Recognition-Mediated Layer-by-Layer Self-Assembled Gold Nanoparticles for Customized Sensitivity in Paper-Based Strip Nanobiosensors

Small. 2019;15(51):1903861.

 

798. Sun C, Lin H, Gong X, Yang Z, Mo Y, Chen X, Gao J.

DOTA-Branched Organic Frameworks as Giant and Potent Metal Chelators

J Am Chem Soc. 2020;142(1):198-206.

 

797. Zhou Z, Shen Z, Chen X

Tale of Two Magnets: A New Design of Magnetic Targeting System

ACS Nano, 2020;14(1):7-11

 

796. Liu Q, Cheng Y, Zang J, Sui Hm Wang H, Jacobson O, Zhu Z, Chen X

Dose Escalation of an Evans Blue Modified Radiolabeled Somatostatin Analogue 177Lu-DOTA-EB-TATE in the Treatment of Metastatic Neuroendocrine Tumors

Eur J Nucl Med Mol Imaging.  2020;47(4):947-957

795. Sun W, Luo L, Feng Y, Cai Y, Zhuang Y, Xie R, Chen X, Chen H

Aggregation-Induced Emission Gold Clustoluminogens for Enhanced Low-Dose X-ray-Induced Photodynamic Therapy

Angew Chem Int Ed Engl, 2019; 58: 1-8

 

794. Huang D, Huang Y, Qiu Q, Wang K, Li Z, Yao Y, Liu G, Zhao Q, Chen X

Three-dimensional label-free imaging of mammalian yolk sac vascular remodeling with optical resolution photoacoustic microscopy

Photoacoustics, 2019;17:100152

 

793. Wu W, Wang X, Shen M, Li L, Yin Y, Shen L, Wang W, Cui D, Ni J, Chen X, Li W.

AIEgens Barcodes Combined with AIEgens Nanobeads for High-sensitivity Multiplexed Detection

Theranostics. 2019;9(24):7210-7221.

 

792. Yang Z, Dai Y, Shan L, Shen Z, Wang Z, Yung BC, Jacobson O, Liu Y, Tang W, Wang S, Lin L, Niu G, Huang P, Chen X

Tumour microenvironment-responsive semiconducting polymer-based self-assembly nanotheranostics

Nanoscale Horiz, 2019;4(2):426-433.

 

791. Li J, Shi Y, Zhang Z, Liu H, Lang L, Liu T, Chen X, Liu Z

A Metabolically Stable Boron-Derived Tyrosine Serves as a Theranostic Agent for Positron Emission Tomography Guided Boron Neutron Capture Therapy

Bioconjug Chem, 2019;30(11):2870-2878.

 

790. Li L, Yang Z, Fan W, He L, Cui C, Zou Z, Tang W, Jacobson O, Wang Z, Niu G, Hu S, Chen X

In situ polymerized hollow mesoporous organosilica biocatalysis nanoreactor for enhancing ROS-mediated anticancer therapy

Adv Funct Mater, 2019;1907716.  

 

789. Feng Y, Ding D, Sun W, Qiu Y, Luo L, Shi T, Meng S, Chen X, Chen H

Magnetic Manganese Oxide Sweetgum-ball Nanospheres with Large Mesopores Regulate Tumor Microenvironments for Enhanced Tumor Nanotheranostics

ACS Appl Mater Interfaces, 2019;11(41):37461-37470

 

788. Yang K, Liu Y, Wang Y, Ren Q, Guo H, Matson JB, Chen X, Nie Z.

Enzyme-induced in vivo assembly of gold nanoparticles for imaging-guided synergistic chemo-photothermal therapy of tumor

Biomaterials 2019;223:119460.

 

787. Chen H, Zhao L, Fu K, Lin Q, Wen X, Jacobson O, Sun L, Wu H, Zhang X, Guo Z, Lin Q, Chen X

Integrin αvβ3-targeted radionuclide therapy combined with immune checkpoint blockade immunotherapy synergistically enhances anti-tumor efficacy

Theranostics, 2019; 9(25):7948-7960.

 

786. Rao L, Yu GT, Meng QF, Bu LL, Zan M, Ding J, Li A, Xiao H, Sun ZJ, Liu W, Chen X

Cancer Cell Membrane-Coated Nanoparticles for Personalized Therapy in Patient-Derived Xenograft Models

Adv Funct Mater, 2019, 1905671

 

785. Xie J, Shen Z, Anraku Y, Kataoka K, Chen X

Nanomaterial-Based Blood-Brain-Barrier (BBB) Crossing Strategies

Biomaterials, 2019;224:119491.

 

784. Lin LS, Wang JF, Song J, Liu Y, Zhu G, Dai Y, Shen Z, Tian R, Song J, Wang Z, Tang W, Yu G, Zhou Z, Yang Z, Huang T, Niu G, Yang HH, Chen ZY, Chen X

Cooperation of endogenous and exogenous reactive oxygen species induced by zinc peroxide nanoparticles to enhance oxidative stress-based cancer therapy

Theranostics 2019; 9(24):7200-7209

 

783. Yang L, Zhou Z, Song J, Chen X

Anisotropic nanomaterials for shape-dependent physicochemical and biomedical applications

Chem Soc Rev, 2019;48(19):5140-5176

 

782. Wang J, Sang W, Yang Z, Shen Z, Wang Z, Jacobson O, Chen Y, Wang Y, Shao M, Niu Dai Y, Chen X

Polyphenol-based nanoplatform for MRI/PET dual-modality imaging guided effective combination chemotherapy

J Mater Chem B, 2019;7(37):5688-5694.

 

781. Yang Z, Fan W, Zou J, Tang W, Li L, He L, Shen Z, Wang Z, Jacobson O, Aronova MA, Rong P, Song J, Wang W, Chen X

Precision Cancer Theranostic Platform by In Situ Polymerization in Perylene Diimide-Hybridized Hollow Mesoporous Organosilica Nanoparticles

J Am Chem Soc, 2019;141(37):14687-14698.

 

780. Jacobson O, Wang Z, Yu G, Ma Y, Chen X, Kiesewetter DO

3-18F-fluoropropane-1-thiol and 18F-PEG4-1-thiol: Versatile prosthetic groups for radiolabeling maleimide functionalized peptides

Bioorg Med Chem. 2019;115041:115041.

 

779. Gao K, Tu W, Yu X, Ahmad F, Zhang X, Wu W, An X, Chen X, Li W

W-doped TiO2 nanoparticles with strong absorption in the NIR-II window for photoacoustic/CT dual-modal imaging and synergistic thermoradiotherapy of tumors

Theranostics. 2019;9(18):5214-5226.

 

778. Zhang Y, Chen X

Nanotechnology and nanomaterials based no-wash electrochemical biosensors: from design to application

Nanoscale, 2019; 11: 19105-19118

 

777. Mu J, He L, Huang P, Chen X

Engineering of Nanoscale Coordination Polymers with Biomolecules for Advanced Applications

Coord Chem Rev, 2019;399:213039.

 

776. Wang S, Yu G, Wang Z, Jacobson O, Li L-S, Yang W, Deng H, He Z, Liu Y, Chen Z-Y, Chen X

Enhanced Anti-Tumor Efficacy by Cascade of Reactive Oxygen Species Generation and Drug Release

Angew Chem Int Ed Engl, 2019;58(41):14758-14763

 

775. Ahmad F, Wang X, Jiang Z, Yu X, Liu X, Mao R, Chen X, Li W

Codoping enhanced radioluminescence of nanoscintillators for X-ray-activated synergistic cancer therapy and prognosis using metabolomics

ACS Nano, 2019;13(9):10419-10433

 

774. Wang C, Fan W, Zhang Z, Wen Y, Xiong L, Chen X

Advanced Nanotechnology Leading the Road of Multimodal Imaging-Guided Precision Surgical Therapy

Adv Mater, 2019;31:1904329

 

773. Huang W, Chen R, Peng Y, Duan F, Huang Y, Guo W, Chen X, Nie L.

In Vivo Quantitative Photoacoustic Diagnosis of Gastric and Intestinal Dysfunctions with a Broad pH-Responsive Sensor

ACS Nano. 2019;13(8):9561-9570.

 

772. Tang L, Yu F, Tang B, Yang Z, Fan W, Zhang M, Wang Z, Jacobson O, Zhou Z, Li L, Liu Y, Kieswetter DO, Tang W, He L, Ma Y, Niu G, Zhang X, Chen X

Tumor Microenvironment-Activated Ultrasensitive Nanoprobes for Specific Detection of Intratumoral Glutathione by Ratiometric Photoacoustic Imaging

ACS Appl Mater Interfaces, 2019;11(31):27558-27567.

 

771. Wu Y, Yuan M, Song J, Chen X, Yang H

Hydrogen Gas from Inflammation Treatment to Cancer Therapy

ACS Nano, 2019;13:8505-8511

 

770. Huang Y, Li M, Huang D, Qiu Q, Lin W, Liu J, Yang W, Yao Y, Yan G, Qu N, Tuchin VV, Fan S, Liu G, Zhao Q, Chen X

Depth-Resolved Enhanced Spectral-Domain OCT Imaging of Live Mammalian Embryos Using Gold Nanoparticles as Contrast Agent

Small, 2019;15(35):e1902346

 

769. Zhu S, Chen X

Fluorescence imaging overcoming the colour barrier

Nat Photonics, 2019;13:515-516.

 

768. Tian R, Zeng Q, Zhu S, Lau J, Chandra S, Ertsey R, Hettie K, Teraphongphom T, Hu Z, Niu G, Kiesewetter DO, Sun H, Zhang X, Antaris AL, Brooks BR, Chen X

Albumin chaperoned cyanine dye yields super bright NIR-II fluorophore with enhanced pharmacokinetics

Sci Adv, 2019;5:eaaw0672

 

767. Deng H, Lin L, Wang S, Yu G, Zhou Z, Liu Y, Niu G, Song J, Chen X

X-ray Controlled Bilayer Permeability of Bionic Nanocapsules Stabilized by Nucleobase Pairing Interactions for Pulsatile Drug Delivery

Adv Mater, 2019;31(37):e1903443.

 

766. Shen Z, Fan W, Yang Z, Liu Y, Bregadze VI, Mandal SK, Yung BC, Lin L, Liu T, Tang W, Shan L, Liu Y, Zhu S, Wang S, Yang W, Bryant LH, Nguyen DT, Wu A, Chen X

Exceedingly Small Gadolinium Oxide Nanoparticles with Remarkable Relaxivities for Magnetic Resonance Imaging of Tumors

Small, 2019;15(41):e1903422

 

765. Liu Y, Gong CS, Dai Y, Yang Z, Yu G, Liu Y, Zhang M, Lin L, Tang W, Zhou Z, Zhu G, Chen J, Jacobson O, Kiesewetter DO, Wang Z, Chen X

In situ polymerization on nanoscale metal-organic frameworks for enhanced physiological stability and stimulus-responsive intracellular drug delivery

Biomaterials, 2019;218:119365.  

 

764. Lin LS, Huang T, Song J, Ou XY, Wang Z, Deng H, Tian R, Liu Y, Wang JF, Liu Y, Yu G, Zhou Z, Wang S, Niu G, Yang HH, Chen X

Synthesis of Copper Peroxide Nanodots for H2O2 Self-Supplying Chemodynamic Therapy

J Am Chem Soc. 2019;141(25):9937-9945.

 

763. Pang X, Liu X, Cheng Y, Zhang C, Ren E, Liu C, Zhang Y, Zhu J, Chen X, Liu G

Sono-Immunotherapeutic Nanocapturer to Combat Multidrug-Resistant Bacterial Infections

Adv Mater. 2019, 1902530.

 

762. Jia TT, Yang G, Mo SJ, Wang ZY, Li BJ, Ma W, Guo YX, Chen X, Zhao X, Liu JQ, Zang SQ

Atomically Precise Gold-Levonorgestrel Nanocluster as a Radiosensitizer for Enhanced Cancer Therapy

ACS Nano. 2019;13(7):8320-8328.

 

761. Zhang J, Tian Y, Li D, Niu G, Lang L, Li F, Liu Y, Zhu Z, Chen X

68Ga-NOTA-Aca-BBN(7-14) PET imaging of GRPR in children with optic pathway glioma

Eur J Nucl Med Mol Imaging. 2019;46(10):2152-2162.

 

760. Wei R, Gong X, Lin H, Zhang K, Li A, Liu K, Shan H, Chen X, Gao J.

A Versatile Octapod-Shaped Hollow Porous Manganese(II) Oxide Nanoplatform for Real-Time Visualization of Cargo Delivery

Nano Lett. 2019;19(8):5394-5402.

 

759. Panwar N, Soehartono AM, Chan KK, Zeng S, Xu G, Qu J, Coquet P, Yong KT, Chen X

Nanocarbons for Biology and Medicine: Sensing, Imaging, and Drug Delivery

Chem Rev. 2019;119(16):9559-9656.

 

758. Sang W, Zhang Z, Dai Y, Chen X

Recent advances in nanomaterial-based synergistic combination cancer immunotherapy

Chem Soc Rev. 2019; 48: 3771-3810 (Back Cover)

 

757. Zhang M, Jacobson O, Kiesewetter DO, Ma Y, Wang Z, Lang L, Tang L, Kang F, Deng H, Yang W, Niu G, Wang J, Chen X

Improving the theranostic potential of exendin 4 by reducing the renal radioactivity through brush border membrane enzyme-mediated degradation

Bioconjug Chem. 2019;30(6):1745-1753.

 

756. Zhou Z, Bai Rm Wang Z, Bryant H, Lang L, Hellmut M, Munasinghe J, Tang L, Tang W, Tian R, Yu G, Ma Y, Niu G, Gao J, Chen X

An Albumin-Binding T1-T2 Dual-modal MRI Contrast Agents for Improved Sensitivity and Accuracy in Tumor Imaging

Bioconjug Chem. 2019; 30(6):1821-1829.

 

755. He Z, Huang X, Wang C, Li X, Liu Y, Zhou Z, Wang S, Zhang F, Wang Z, Jacobson O, Zhu JJ, Yu G, Dai Y, Chen X.

A Catalase-Like Metal-Organic Framework Nanohybrid for O2 -Evolving Synergistic Chemoradiotherapy.

Angew Chem Int Ed Engl. 2019; 58(26):8752-8756.

 

754. Tian R, Zhu S, Zeng Q, Lang L, Ma Y, Kiesewetter D, Liu Y, Fu X, Lau J, Zhu G, Jacobson O, Wang Z, Dai Y, Yu G, Brooks B, Liu G, Niu G, Chen X.

An albumin sandwich enhances in vivo circulation and stability of metabolically labile peptides.

Bioconjug Chem. 2019; 30(6):1711-1723.

 

753. Caisova V, Li L, Gupta G, Jochmanova I, Jha A, Uher O, Huynh TT, Miettinen M, Pang Y, Abunimer L, Niu G, Chen X, Ghayee HK, Taïeb D, Zhuang Z, Zenka J, Pacak K.

The Significant Reduction or Complete Eradication of Subcutaneous and Metastatic Lesions in a Pheochromocytoma Mouse Model after Immunotherapy Using Mannan-BAM, TLR Ligands, and Anti-CD40.

Cancers (Basel). 2019; 11(5): 654.

 

752. He L, Liu Y, Lau J, Fan W, Li Q, Zhang C, Huang P, Chen X

Recent progress in nanoscale metal-organic frameworks for drug release and cancer therapy.

Nanomedicine (Lond). 2019;14(10):1343-1365

 

751. Tang W, Fan W, Lau J, Deng L, Shen Z, Chen X

Emerging blood-brain-barrier-crossing nanotechnology for brain cancer theranostics.

Chem Soc Rev. 2019; 48(11): 2967-3014.

 

750. Chen X, Song J, Chen X, Yang H.

X-ray-activated nanosystems for theranostic applications

Chem Soc Rev. 2019; 48(11): 2967-3014.

 

749. Shan L, Gao G, Wang W, Tang W, Wang Z, Yang Z, Fan W, Zhu G, Zhai K, Jacobson O, Dai Y, Chen X

Self-assembled green tea polyphenol-based coordination nanomaterials to improve chemotherapy efficacy by inhibition of carbonyl reductase 1

Biomaterials, 2019; 210: 62-69.

 

748. Zhu S, Tian R, Antaris AL, Chen X, Dai H.

Near-Infrared-II Molecular Dyes for Cancer Imaging and Surgery

Adv Mater. 2019; 31: 1900321.

 

747. Yu G, Cen TY, He Z, Wang SP, Wang Z, Ying XW, Li S, Jacobson O, Wang S, Wang L, Lin L, Tian R, Zhou Z, Ni Q, Li X, Chen X

Porphyrin Nanocage-Embedded Single Molecular Nanoparticle as Cancer Nanotheranostics

Angew Chem Int Ed Engl. 2019; 58(26): 8799-8803.

 

746. Hou G, Hou B, Jiang Y, Zhu Z, Long X, Chen X, Cheng W

68Ga-NOTA-Evans Blue TOF PET/MR Lymphoscintigraphy Evaluation of the Severity of Lower Limb Lymphedema

Clin Nucl Med. 2019;44(6):439-445.

 

745. Liu Y, Yang Y, Sun Y, Song J, Rudawski NG, Chen X, Tan W

Ostwald ripening-mediated grafting of metal-organic frameworks on a single colloidal nanocrystal to form uniform and controllable MXF

J Am Chem Soc. 2019;141(18):7407-7413.

 

744. Tian R, Shen Z, Zhou Z, Munasinghe J, Zhang X, Jacobson O, Zhang M, Niu G, Pang D-W, Cui R, Zhu S, Chen X

Ultra-small quantum dots with broad-spectrum metal doping ability for trimodal molecular imaging

Adv Funct Mater, 2019; 1901671.  

 

743. Lv P, Liu X, Chen X, Liu C, Zhang Y, Chu C, Wang J, Wang X, Chen X, Liu G

Genetically Engineered Cell Membrane Nanovesicles for Oncolytic Adenovirus Delivery: A Versatile Platform for Cancer Virotherapy

Nano Lett. 2019;19(5):2993-3001.

 

742. Yang Z, Chen X

Semiconducting Perylene Diimide Nanostructure: Multifunctional Phototheranostic Nanoplatform

Acc Chem Res, 2019; 52(5): 1245-1254.

 

741. Wang S, Zhou Z, Wang Z, Liu Y, Jacobson O, Shen Z, Fu X, Chen ZY, Chen X

Gadolinium Metallofullerene-Based Activatable Contrast Agent for Tumor Signal Amplification and Monitoring of Drug Release

Small, 2019;15(16):1900691.

 

740. Chu C, Su M, Zhu J, Li D, Wang J, Chen X, Liu G

Metal-Organic Framework Nanoparticle-Based Biomineralization: A New Strategy toward Cancer Treatment      

Theranostics, 2019;9:3134-3149.  

 

739. Liu Y, Zhao Y, Chen X

Bioengineering of Metal-organic Frameworks for Nanomedicine

Theranostics, 2019;9:3122-3133.  

 

738. Yu G, Chen X

Host–Guest Chemistry in Supramolecular Theranostics

Theranostics 2019;9:3041-3074.

 

737. Li L, Yang Z, Zhu S, He L, Fan W, Tang W, Zou J, Shen Z, Zhang M, Tang L, Dai Y, Niu G, Hu S, Chen X

A Rationally Designed Semiconducting Polymer Brush for NIR-II Imaging-Guided Light-Triggered Remote Control of CRISPR/Cas9 Genome Editing

Adv Mater, 2019;31:1901187

 

736. Tian R, Ma H, Yang Q, Wan H, Zhu S, Chandra S, Sun H, Kiesewetter DO, Niu G, Liang Y, Chen X

Rational design of a super-contrast NIR-II fluorophore affords high-performance NIR-II molecular imaging guided microsurgery

Chem Sci. 2018;10(1):326-332.

 

735. Liu X, Liu C, Zheng Z, Chen S, Pang X, Xiang X, Tang J, Ren E, Chen Y, You M, Wang X, Chen X, Luo W, Liu G, Xia N

Vesicular Antibodies: A Bioactive Multifunctional Combination Platform for Targeted Therapeutic Delivery and Cancer Immunotherapy

Adv Mater. 2019;31:1808294.

 

734. Yu G, Zhu B, Shao L. Zhou J, Saha ML, Shi B, Zhang Z, Hong T, Li S, Chen X, Stang PJ

Host−guest complexation-mediated codelivery of anticancer drug and photosensitizer for cancer photochemotherapy

PNAS, 2019; 116: 6618-6623

 

733. Wang S, Wang Z, Yu G, Zhou Z, Jacobson O, Liu Y, Ma Y, Zhang F, Chen ZY, Chen X

Tumor-Specific Drug Release and Reactive Oxygen Species Generation for Cancer Chemo/Chemodynamic Combination Therapy

Adv Sci (Weinh). 2019;6(5):1801986.

 

732. Xia Y, Xu C, Zhang X, Ning P, Wang Z, Tian J, Chen X

Liposome-based probes for molecular imaging: from basic research to the bedside

Nanoscale. 2019;11(13):5822-5838.

 

731. Tang W, Fan W, Zhang W, Yang Z, Li L, Wang Z, Chiang Y-L, Liu Y, Deng L, He L, Shen Z, Jacobson O, Aronova MA, Jin A, Xie J, Chen X

Wet/Sono-Chemical Synthesis of Enzymatic Two-Dimensional MnO2 Nanosheets for Synergistic Catalysis-Enhanced Phototheranostics

Adv Mater, 2019;31:1900401

 

730. Sun W, Shi T, Luo J, Chen X, Lv P, Lv Y, Zhang Y, Zhu J, Liu G, Chen X, Chen H

Monodisperse and uniform mesoporous silicate nanosensitizers achieve low-dose X-ray induced deep-penetrating photodynamic therapy

Adv Mater, 2019;31:1808024

 

729. Yang W, Zhou Z, Lau J, Hu S, Chen X

Functional T Cell Activation by Smart Nanosystems for Effective Cancer Immunotherapy

Nano Today, 2019;27:28-47.

 

728. Liu Y, Gong CS, Dai Y, Wang Z, Yang Z, Yu G, Liu Y, Zhang M, Lin L, Tang W, Zhou Z, Zhu G, Chen J, Jacobson O, Kiesewetter DO, Chen X

Core-shell metal-organic frameworks with fluorescence switch to trigger an enhanced photodynamic therapy

Theranostics, 2019; 9(10): 2791-2799.

 

727. Wang J, Zang J, Wang H, Liu Q, Li F, Lin Y, Huo L, Jacobson O, Niu G, Fan X, Zhu Z, Chen X

Pretherapeutic 68Ga-PSMA-617 PET May Indicate the Dosimetry of 177Lu-PSMA-617 and 177Lu-EB-PSMA-617 in Main Organs and Tumor Lesions

Clin Nucl Med. 2019; 44(6):431-438.

 

726. Yang W, Zhu G, Wang S, Yu G, Yang Z, Lin L, Zhou Z, Liu Y, Dai Y, Zhang F, Shen Z, Liu Y, He Z, Lau J, Niu G, Kiesewetter DO, Hu S, Chen X

In Situ Dendritic Cell Vaccine for Effective Cancer Immunotherapy

ACS Nano, 2019;13(3):3083-3094.

 

725. Shan L, Fan W, Wang W, Tang W, Yang Z, Wang Z, Liu Y, Shen Z, Dai Y, Cheng S, Jacobson O, Zhai K, Hu J, Ma Y, Kiesewetter DO, Gao G, Chen X

Organosilica-Based Hollow Mesoporous Bilirubin Nanoparticles for Antioxidation-Activated Self-Protection and Tumor-Specific Deoxygenation-Driven Synergistic Therapy

ACS Nano, 2019;13:8903-8916.

 

724. Yu X, Liu X, Wu W, Yang K, Mao R, Ahmad F, Chen X, Li W

CT/MRI-Guided Synergistic Radiotherapy and X-ray Inducible Photodynamic Therapy Using Tb-Doped Gd-W-Nanoscintillators

Angew Chem Int Ed Engl. 2019;58(7):2017-2022.

 

723. Zhou Z, Yang L, Gao J, Chen X

Structure-Relaxivity Relationships of Magnetic Nanoparticles for Magnetic Resonance Imaging

Adv Mater. 2019;31:1804567.

 

722. Song J, Lin L, Yang Z, Zhu R, Zhou Z, Li Z-W, Wang F, Chen J, Yang H, Chen X

Self-Assembled Responsive Bilayered Vesicles with Adjustable Oxidative Stress for Enhanced Cancer Imaging and Therapy

J Am Chem Soc, 2019; 141: 8158-8170.

 

721. Fan W, Lu N, Shen Z, Tang W, Shen B, Cui Z, Shan L, Yang Z, Wang Z, Jacobson O, Zhou Z, Liu Y, Hu P, Yang W, Song J, Zhang Y, Zhang L, Khashab NM, Aronova MA, Lu G, Chen X

Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy

Nat Comm, 2019;10:1241.  

 

720. Pang X, Xiao Q, Cheng Y, Ren E, Lian L, Zhang Y, Gao H, Wang X, Leung W, Chen X, Liu G, Xu C.

Bacteria-Responsive Nanoliposomes as Smart Sonotheranostics for Multidrug Resistant Bacterial Infections

ACS Nano. 2019;13(2):2427-2438.

 

719. Li S, Liu R, Jiang X, Qiu Y, Song X, Huang G, Fu N, Lin L, Song J, Chen X, Yang H

Near-Infrared Light Triggered Sulfur Dioxide Gas Therapy of Cancer

ACS Nano, 2019;13(2):2103-2113.

 

718. Tang L, Yang Z, Zhou Z, Ma Y, Kiesewetter DO, Wang Z, Fan W, Zhu S, Zhang M, Tian R, Lang L, Niu G, Zhang X, Chen X

A logic-gated modular nanovesicle enables programmable drug release for on-demand chemotherapy

Theranostics, 2019; 9(5):1358-1368

 

717. Lau J, Jacobson O, Niu G, Lin KS, Benard F, Chen X

Bench to Bedside: Albumin Binders for Improved Cancer

Bioconjug Chem, 2019;30:487-502.

 

716. Jacobson Weiss O, Chen X

Reply to: Different radionuclides in DOTA-EB-TATE effect different uptake in somatostatin receptor positive HEK293 cells

J Nucl Med. 2019;60:436-437.

 

715. Yu X, Liu X, Wu W, Yang K, Mao R, Chen X, Li W

Computed Tomography and Magnetic Resonance Imaging-Guided Synergistic Radiotherapy and X-ray Inducible Photodynamic Therapy Using Tb-Doped Gadolinium Tungstate Nanoscintillators.

Angew Chem Int Ed Engl. 2019;58(7):2017-2022.

 

714. Deng H, Dong A, Song J, Chen X

Injectable Thermosensitive Hydrogel Systems Based on Functional PEG/PCL Block Polymer for Local Drug Delivery

J Control Release, 2019;297:60-70.

 

713. Wang S, Yu G, Ma Y, Yang Z, Liu Y, Wang J, Chen X

Ratiometric Photoacoustic Nanoprobe for Bioimaging of Cu2+

ACS Appl Mater Interfaces, 2019;11:1917-1923.

 

712. He L, Liu Y, Lau J, Fan W, Li Q, Zhang C, Huang P, Chen X

Recent progress in nanoscale metal-organic frameworks for drug release and cancer therapy

Nanomedicine, 2019;14(10):1343-1365

 

711. Yang Z, Song J, Tang W, Fan W, Dai Y, Shen Z, Lin L, Cheng S, Liu Y, Niu G, Rong P, Wang W, Chen X

Stimuli-responsive nanotheranostics for real-time monitoring drug release by photoacoustic imaging

Theranostics, 2019; 9(2): 526-536

 

710 Ni Q, Pham NB, Meng WS, Zhu G, Chen X

Advances in Immunotherapy of Type I Diabetes

Adv Drug Deliv Rev, 2019;139:83-91.

 

709. Fan W, Tang W, Lau J, Shen Z, Xie J, Shi J, Chen X

Breaking the depth dependence by nanotechnology-enhanced X-ray-excited deep theranostics

Adv Mater, 2019;31:1806381

 

708. Chu C, Ren E, Zhang Y, Yu J, Lin H, Pang X, Zhang Y, Liu H, Qin Z, Cheng Y, Wang X, Li W, Kong X, Chen X, Liu G

Zinc(II)-dipicolylamine Coordination Nanotheranostics: Toward Synergistic Nanomedicine by Combined Photo/gene Therapy

Angew Chem Int Ed Engl. 2019;58(1):269-272.

 

707. Liu Y, Bhattarai P, Dai Z, Chen X

Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer

Chem Soc Rev. 2019;48(7):2053-2108.

716. He Z, Dai Y, Li X, Guo D, Liu Y, Huang X, Jiang J, Wang S, Zhu G, Zhang F, Lin L, Zhu JJ, Yu G, Chen X

Hybrid Nanomedicine Fabricated from PhotosensitizerTerminated Metal–Organic Framework Nanoparticles for Photodynamic Therapy and Hypoxia-Activated Cascade Chemotherapy

Small, 2018;15(4):e1804131

 

705. Tian BP, Li F, Li R, Hu X, Lai TW, Lu J, Zhao Y, Du Y, Liang Z, Zhu C, Shao W, Li W, Chen ZH, Sun X, Chen X, Ying S, Ling D, Shen H.

Nanoformulated ABT-199 to effectively target Bcl-2 at mitochondrial membrane alleviates airway inflammation by inducing apoptosis

Biomaterials. 2018;192:429-439.

 

704. Wang S, Wang Z, Yu G, Zhou Z, Jacobson O, Liu Y, Ma Y, Zhang F, Chen ZY, Chen X

Tumor-Specific Drug Release and Reactive Oxygen Species Generation for Cancer Chemo/Chemodynamic Combination Therapy

Adv Sci, 2018;1801986.

 

703. Tang W, Fan W, Wang Z, Zhang W, Zhou S, Liu Y, Yang Z, Shao E, Zhang G, Jacobson O, Shan L, Tian R, Cheng S, Lin L, Dai Y, Shen Z, Niu G, Xie J, Chen X

Acidity/Reducibility Dual-Responsive Hollow Mesoporous Organosilica Nanoplatforms for Tumor-Specific Self-Assembly and Synergistic Therapy

ACS Nano. 2018;12(12):12269–12283.

 

702. Zhang P, Wang J, Chen H, Zhao L, Chen B, Chu C, Liu H, Qin Z, Liu J, Tan Y, Chen X, Liu G

Tumor Microenvironment-Responsive Ultrasmall Nanodrug Generators with Enhanced Tumor Delivery and Penetration

J Am Chem Soc. 2018;140(44):14980-14989.

 

701. Shen Z, Liu T, Li Y, Lau J, Yang Z, Fan W, Zhou Z, Shi C, Ke C, Bregadze VI, Mandal SK, Liu Y, Li Z, Xue T, Zhu G, Munasinghe J, Niu G, Wu A, Chen X

Fenton-Reaction-Acceleratable Magnetic Nanoparticles for Ferroptosis Therapy of Orthotopic Brain Tumors

ACS Nano. 2018;12(11):11355-11365.

 

700. Zhou Z, Yang L, Gao J, Chen X

Structure-Relaxivity Relationships of Magnetic Nanoparticles for Magnetic Resonance Imaging

Adv Mater, 2018, 1804567

 

699. Fu Q, Zhu R, Song J, Yang H, Chen X

Photoacoustic Imaging: Contrast Agents and their Biomedical Applications

Adv Mater, 2018, 1805875

 

698. Shi C, Liu T, Guo Z, Zhuang R, Zhang X, Chen X

Reprogramming Tumor-Associated Macrophages by Nanoparticle-based Reactive Oxygen Species Photogeneration

Nano Lett. 2018;18(11):7330-7342

 

697. He C, Jiang S, Yao H, Zhang L, Yang C, Jiang S, Ruan F, Zhan D, Liu G, Lin Z, Lin Y, Chen X

High-content analysis for mitophagy response to nanoparticles: A potential sensitive biomarker for nanosafety assessment

Nanomedicine. 2018; 15(1):59-69.

 

696. Niu G, Wang G, Lang L, Jacobson O, Ma Y, Kiesewetter DO, Zhang S, Chen X

Anti-Diabetic Effect of Abextide, a Long-Acting Exendin-4 Analogue in Cynomolgus Monkeys

Adv Healthc Mater, 2018,1800686.

 

695. Wang S, Yu G, Wang Z, Jacobson O, Tian R, Lin LS, Zhang F, Wang J, Chen X

Hierarchical Tumor Microenvironment-Responsive Nanomedicine for Programmed Delivery

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Adv Mater, 2018;30:e1803926

 

694. Yang Z, Fan W, Tang W, Shen Z, Dai Y, Song J, Wang Z, Liu Y, Lin L, Shan L, Liu Y, Jacobson O, Rong P, Wang W, Chen X

Hybrid of Near-Infrared Semiconducting Polymer Brush and pH/GSH-responsive Polyoxometalate Cluster for Enhanced Tumor-Specific Phototheranostics

Angew Chem Int Ed Engl, 2018;57(43):14101-14105

 

693. Yu G, Yu S, Lal Saha M, Zhou J, Cook TR, Yung BC, Chen J, Mao Z, Zhang F, Zhou Z Liu Y, Shao L, Wang S, Gao C, Huang F, Stang PJ, Chen X

A discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy

Nat Commun, 2018;9(1):4335

 

692. Zhu G, Chen X

Aptamer-based targeted therapy

Adv Drug Deliv Rev, 2018;134:65-78

 

691. Li D, Zhang J, Ji N, Zhao X, Zheng K, Qiao Z, Li F, Lang L, Iagaru A, Niu G, Zhu Z, Chen X

Combined 68Ga-NOTA-PRGD2 and 18F-FDG PET/CT Can Discriminate Uncommon Meningioma Mimicking High-Grade Glioma

Clin Nucl Med. 2018;43(9):648-654.

 

690. Liu X, Yuan L, Zhang L, Mu Y, Li X, Liu C, Lv P, Zhang Y, Cheng T, Yuan Q, Xia N, Chen X, Liu G

Bioinspired Artificial Nanodecoys for Hepatitis B Virus

Angew Chem Int Ed Engl. 2018;57(38):12499-12503.

 

689. Lim K, Ropchan J, Kiesewetter DO, Chen X, Huang Y

Automated radiosynthesis of [18F]FBEM, a sulfhydryl site specific labeling agent for peptides and proteins

Appl Radiat Isot. 2018;140:294-299.

 

688. Wang Z, Tian R, Niu G, Ma Y, Lang L, Szajek L, Kiesewetter DO, Jacobson O, Chen X

Single Low-Dose Injection of Evans Blue Modified PSMA-617 Radioligand Therapy Eliminates Prostate-Specific Membrane Antigen Positive Tumors

Bioconjug Chem. 2018;29(9):3213-3221.

 

687. Cheng S, Jaocobson O, Zhu Z, Chen Z, Liang SH, Tian R, Yang Z, Niu G, Zhu X, Chen X

PET Imaging of EGFR Expression Using an 18F-labeled RNA Aptamer

Eur J Nucl Med Mol Imaging, 2018;46(4):948-956.

 

686. Zang J, Fan X, Wang H, Liu Q, Wang J, Li H, Li F, Jacobson O, Niu G, Zhu Z, Chen X

First-in-Human Study of 177Lu-EB-PSMA-617 in Patients with Metastatic Castration-Resistant Prostate Cancer

Eur J Nucl Med Mol Imaging, 2019;46(1):148-158.

 

685. Wang S, Zhou Z, Yu G, Lu N, Liu Y, Dai Y, Fu X, Wang J, Chen X

Gadolinium Metallofullerene-Polypyrrole Nanoparticles for Activatable Dual-Modal Imaging Guided Photothermal Therapy

ACS Appl Mater Interfaces, 2018;10(34):28382-28389.

 

685. Zhu S, Yung BC, Chandra S, Niu G, Antaris AL, Chen X

Near-Infrared-II (NIR-II) Bioimaging via Off-Peak NIR-I Fluorescence Emission

Theranostics 2018; 8(15):4141-4151.

 

684. Liu Y, Yang Z, Huang X, Yu G, Wang S, Zhou Z, Shen Z, Fan W, Liu Y, Davisson M, Kalish H, Niu G, Nie Z, Chen X

Glutathione-Responsive Self-Assembled Magnetic Gold Nanowreath for Enhanced Tumor Imaging and Imaging-Guided Photothermal Therapy

ACS Nano, 2018;12(8):8129-8137.

 

683. He S, Li C, Zhang Q, Ding J, Liang XJ, Chen X, Xiao H, Chen X, Zhou D, Huang Y

Tailoring Platinum(IV) Amphiphiles for Self-Targeting All-in-One Assemblies as Precise Multimodal Theranostic Nanomedicine

ACS Nano, 2018;12(7):7272-7281.

 

682. Bandara N, Jacobson O, Mpoy C, Chen X, Rogers BE

Novel Structural Modification Based on Evans Blue Dye to Improve Pharmacokinetics of a Somastostatin-Receptor-Based Theranostic Agent

Bioconjug Chem 2018; 29(7): 2448-2454.

 

681. Huang X, Liu Y, Barr J, Song J, He Z, Wang Y, Nie Z, Xiong Y, Chen X

Controllable self-assembled plasmonic vesicle-based three-dimensional SERS platform for picomolar detection of hydrophobic contaminants

Nanoscale. 2018;10(27):13202-13211.

 

680. Yu G, Zhao X, Zhou J, Mao Z, Huang X, Wang Z, Hua Bm Liu Y, Zhang F, He Z, Jacobson O, Gao C, Wang W, Yu C, Zhu X, Huang F, Chen X

Supramolecular Polymer-Based Nanomedicine: High Therapeutic Performance and Negligible Long-Term Immunotoxicity

J Am Chem Soc, 2018;140(25):8005-8019.

 

679. Chen H, Qiu Y, Ding D, Wang GD, Huang W, Liu G, Xie J, Chen X

Gadolinium-encapsulated graphene carbon nanotheranostics for imaging-guided photodynamic therapy

Adv Mater, 2018;30:1802748

 

678. Zhu S, Hu Z, Tian R, Yung BC, Yang Q, Zhao S, Kiesewetter DO, Niu G, Sun H, Antaris AL, Chen X

Repurposing cyanine NIR-I dyes for near-infrared-II (NIR-II) bioimaging

Adv Mater, 2018;30:1802546

 

677. Zang J, Mao F, Zhang J, Wang H, Liu Q, Jacobson O, Chen X, Zhu Z

68Ga-NOTA-RM26 PET/CT in the Evaluation of Breast Cancer: A Pilot Prospective Study

Clin Nucl Med, 2018;43(9):663-669.

 

676. Wang Z, Jacobson O, Tian R, Mease RC, Kiesewetter DO, Niu G, Pomper MG, Chen X

Radioligand Therapy of Prostate Cancer with a Long-lasting PSMA Targeting Agent 90Y-DOTA-EB-MCG

Bioconjug Chem, 2018;29(7):2309-2315

 

675. Shen Z, Song J, Zhou Z, Yung BC, Aronova MA, Li Y, Dai Y, Fan W, Liu Y, Li Z, Ruan H, Leapman RD, Lin L, Niu G, Chen X, Wu A

Dotted Core-Shell Nanoparticles for T1-Weighted MRI of Tumors

Adv Mater, 2018;30:1803163

 

674. Thompson SJ, Pitcher MH, Stone LS, Tarum F, Niu G, Chen X, Kiesewetter DO, Schweinhardt P, Bushnell MC.

Chronic neuropathic pain reduces opioid receptor availability with associated anhedonia in rat

Pain. 2018;159(9):1856-1866.

 

673. Lin G, Zhang Y, Zhu C, Chu C, Shi Y, Pang X, Ren E, Wu Y, Mi P, Xia H, Chen X, Liu G

Photo-excitable Hybrid Nanocomposites for Image-guided Photo/TRAIL Synergistic Cancer Therapy

Biomaterials, 2018;176:60-70.

 

672. Mu J, Lin J, Huang P, Chen X

Enzyme-Responsive Nanomaterials for Theranostics

Chem Soc Rev, 2018;47(15):5554-5573.

 

671. Zhou Z, Chan A, Wang Z, Huang X, Yu G, Jacobson O, Wang S, Liu Y, Shan L, Dai Y, Shen Z, Lin L, Chen W, Chen X

Synchronous Chemoradiation Nanovesicles by X-ray Triggered Cascade of Drug Release

Angew Chem Int Ed Engl, 2018;57(28):8463-8467.

 

670. Jung S, Chen X

Quantum Dot-Dye Conjugates for Biosensing/Imaging and Therapy

Adv Healthc Mater, 2018;7:1800252

 

669. Huang X, He Z, Guo D, Liu Y, Song J, Yung BC, Lin L, Yu G, Zhu JJ, Xiong Y, Chen X

“Three-in-one” Nanohybrids as Synergistic Nanoquenchers to Enhance No-Wash Fluorescence Biosensors for Ratiometric Detection of Cancer Biomarkers

Theranostics, 2018;8:3461-3473.

 

668. Wang H, Cheng Y, Zhang J, Zang J, Li H Liu Q, Wang J, Jacobson O, Li F, Zhu Z, Chen X

Response to Single Low-dose 177Lu-DOTA-EB-TATE Treatment in Patients with Advanced Neuroendocrine Neoplasm: A Prospective Pilot Study

Theranostics, 2018;8:3308-3316

 

667. Wang X, Gao S, Qin Z, Tian R, Wang G, Zhang X, Zhu L, Chen X

Evans Blue Derivative Functionalized Gold Nanorods for Photothermal Therapy Enhanced Tumor Chemotherapy

ACS Appl Mater Interfaces, 2018;10(17):15140-15149.

 

666. Zhang J, Wang H, Jacobson Weiss O, Cheng Y, Niu G, Li F, Bai C, Zhu Z, Chen X

Safety, Pharmacokinetics and Dosimetry of a Long-Acting Radiolabeled Somatostatin Analogue 177Lu-DOTA-EB-TATE in Patients with Advanced Metastatic Neuroendocrine Tumors.

J Nucl Med. 2018 Apr 13. pii: jnumed.118.209841. doi: 10.2967/jnumed.118.209841.

 

665. Li L, Hu S, Chen X

Non-viral delivery systems for CRISPR/Cas9-based genome editing: challenges and opportunities

Biomaterials, 2018;171:207-218.

 

664. Tang L, Peng C, Tang B, Li Z, Wang X, Li J, Gao F, Huang L, Xu D, Zhang P, Zhuang R, Sun X, Chen X, Zhang X

Radioiodinated Small Molecule Tyrosine Kinase Inhibitor for HER2 Selective SPECT Imaging

J Nucl Med, 2018; 59(9):1386-1391.

 

663. Liu H, Chu C, Liu Y, Pang X, Wu Y, Zhou Z, Zhang P, Zhang W, Liu G, Chen X

Novel intrapolymerization doped manganese-eumelanin coordination nanocomposites with ultrahigh relaxivity and their application in cancer theranostics

Adv Sci, 2018;5(7):1800032.

 

662. Watson DC, Yung BC, Bergamaschi C, Chowdhury B, Bear J, Stellas D, Morales-Kastresana A, Jones JC, Felber BK, Chen X, Pavlakis GN.

Scalable, cGMP-compatible purification of extracellular vesicles carrying bioactive human heterodimeric IL-15/lactadherin complexes

J Extracell Vesicles. 2018;7(1):1442088.

 

661. Huang X, Song J, Yung BC, Huang X, Xiong Y, Chen X

Ratiometric optical nanoprobes enable accurate molecular detection and imaging

Chem Soc Rev, 2018; 47(8):2873-2920.

 

660. Yang K, Liu Y, Liu Y, Zhang Q, Kong C, Yi C, Zhou Z, Wang Z, Zhang G, Zhang Y, Khashab N, Chen X, Nie Z

Cooperative Assembly of Magneto-nanovesicles with Tunable Wall Thickness and Permeability for MRI-guided Drug Delivery

J Am Chem Soc, 2018;140(13):4666-4677.

 

659. Yang Z, Dai Ym Yin C, Fan Q, Zhang W, Song J, Yu G, Tang W, Fan W, Yung BC, Li J, Li X, Li X, Tang Y, Huang W, Song J, Chen X

Activatable Semiconducting Theranostics: Simultaneous Generation and Ratiometric Photoacoustic Imaging of Reactive Oxygen Species In Vivo

Adv Mater, 2018;30:1707509

 

658. Wu J, Wang S, Zhang X, Teng Z, Tian J, Sun C, Wang X, Wang J, Zhu H, Yung BC, Niu G, Lu G, Chen X

18F-Alfatide II PET/CT for Identification of Breast Cancer: A Preliminary Clinical Study

J Nucl Med, doi: 10.2967/jnumed.118.208637

 

657. Zhang F, Ni Q, Jacobson O, Cheng S, Liao A, Wang Z, He Z, Yu G, Song J, Ma Y, Niu G, Zhang L, Zhu G, Chen X

Polymeric Nanoparticles with Glutathione-Sensitive Heterodimeric Multifunctional Prodrug for Combined Photodynamic Therapy and Chemotherapy

Angew Chem Int Ed Engl, 2018;57:7066 –7070

 

656. Yoon YI, Pang X, Jung S, Zhang G, Kong M, Liu G, Chen X

Smart Gold Nanoparticle-Stabilized Ultrasound Microbubbles as Cancer Theranostics

J Mater Chem B, 2018,6, 3235-3239

 

655. Tang L, Sun X, Liu N, Zhou Z, Yu F, Zhang X, Sun X, Chen X

Radiolabeled Angiogenesis-Targeting Croconaine Nanoparticles for Trimodality Imaging Guided Photothermal Therapy of Glioma

ACS Appl Nano Mater, 2018;1(4):1741–1749.

 

654. Lin LS, Song J, Song l, Ke K, Liu Y, Zhou Z, Shen Z, Li J, Yang Z, Tang W, Niu G, Yang HH, Chen X

Simultaneous Fenton-Like Ion Delivery and Glutathione Depletion by MnO2-Based Nanoagent Enhances Chemodynamic Therapy

Angew Chem Int Ed Engl, 2018;57:4902–4906

 

653. Fan W, Yung BC, Chen X

Stimuli-Responsive NO Release for On-Demand Gas-Sensitized Synergistic Cancer Therapy

Angew Chem Int Ed Engl, 2018;57:2–14

 

652. Yu G, Yang J, Fu X, Wang Z, Shao L, Mao Z, Liu Y, Yang Z, Zhang F, Fan W, Song J, Zhou Z, Gao C, Huang F, Chen X

Supramolecular Hybrid Material Constructed from Graphene Oxide and Pillar[6]arene-Based Host–Guest Complex as a Ultrasound and Photoacoustic Signal Nanoamplifier

Mater Horiz, 2018;5:429-435

 

651. Li D, Zhang J, Chi C, Xiao X, Wang J, Lang L, Ali I, Niu G, Zhang L, Tian J, Ji N, Zhu Z, Chen X

First-in-human study of PET and optical dual-modality image-guided surgery in glioblastoma using 68Ga-IRDye800CW-BBN

Theranostics, 2018; 8(9):2508-2520.

 

650. Tang W, Yang Z, Wang S, Wang Z, Song J, Yu G, Fan W, Dai Y, Wang J, Shan L, Niu G, Fan Q, Chen X

Organic Semiconducting Photoacoustic Nanodroplets for Laser-Activatable Ultrasound Imaging and Combinational Cancer Therapy

ACS Nano, 2018;12(3):2610-2622.

 

649. Niu G, Chen X

When radionuclides meet nanoparticles

Nat Nanotechnol, 2018;13(5):359-360.

 

648. Shan L, Zhou X, Zhang F, Dai Y, Zhu G, Yung BC, Fan W, Zhai K, Jacobson O, Kiesewetter DO, Ma Y, Gao G, Chen X

A paclitaxel prodrug with bifunctional folate and albumin binding moieties for both passive and active targeted cancer therapy

Theranostics, 2018; 8(7):2018-2030

 

647. Chen W, Yung BC, Qian Z, Chen X

Improving long-term subcutaneous drug delivery by regulating material-bioenvironment interaction

Adv Drug Deliv Rev. 2018;127:20-34.

 

646. Zhang P, Zhuang R, Wang X, Su X, Chen X, Zhang X

Highly efficient and stable strain-release radioiodination for thiol chemoselective bioconjugation

Bioconjug Chem, 2018;29(2):467-472.

 

645. Zhang D, Zhuang R, Guo Z, Gao M, Huang L, You L, Zhang P, Li J, Su X, Wu H, Chen X, Zhang X

Desmin and Vimentin Mediated Hepatic Stellate Cells Targeting Radiotracer 99mTc-GlcNAc-PEI for Liver Fibrosis Imaging with SPECT

Theranostics, 2018; 8(5): 1340-1349.

 

644. Dai Y, Cheng S, Wang Z, Zhang R, Yang Z, Wang J, Yung BC, Wang Z, Jacobson O, Xu C, Ni Q, Yu G, Zhou Z, Chen X

Hypochlorous Acid Promoted Platinum Drug Chemotherapy by Myeloperoxidase Encapsulated Therapeutic Metal Phenolic Nanoparticles

ACS Nano, 2018; 12 (1):455–463.

 

643. Lu N, Fan W, Yi X, Wang S, Wang Z, Tian R, Jacobson O, Liu Y, Yung BC, Zhang G, Teng Z, Yang K, Zhang M, Niu G, Lu G, Chen X

Biodegradable Hollow Mesoporous Organosilica Nanotheranostics for Mild Hyperthermia-Induced

Bubble-Enhanced Oxygen-Sensitized Radiotherapy

ACS Nano, 2018; 12 (2): 1580–1591

 

642. Yang X, Liu Z, Zhang H, Li Z, Munasinghe JP, Niu G, Teng G, Chen X

Preclinical evaluation of an 18F-trifluoroborate methionine derivative for glioma imaging

Eur J Nucl Med Mol Imaging. 2018; 45(4):585-592.

 

641. Yu G, Yung BC, Zhou Z, Chen X

Artificial Molecular Machines in Nanotheranostics

ACS Nano, 2018; 12 (1): 7–12

 

640. Jadvar H, Chen X, Cai W, Mahmood U.

Radiotheranostics in Cancer Diagnosis and Management

Radiology, 2018;286(2):388-400.

 

639. Zhang J, Mao F, Niu G, Peng L, Lang L, Li F, Ying H, Wu H, Pan B, Zhu Z, Chen X

68Ga-BBN-RGD PET/CT for GRPR and Integrin αvβ3 Imaging in Patients with Breast Cancer

Theranostics, 2018;8(4):1121-1130.

 

638. Yu G, Yang Z, Fu X, Yung BC, Yang J, Mao Z, Shao L, Hua B, Liu Y, Zhang F, Fan Q, Wang S, Jacobson O, Jin A, Gao C, Tang X, Huang F, Chen X

Polyrotaxane Based Supramolecular Theranostics

Nat Comm, 2018; 9(1):766.

 

637. Lin L, Song J, Yang H-H, Chen X

Yolk-Shell Nanostructures: Design, Synthesis, and Biomedical Applications

Adv Mater, 2018;30:1704639

 

636. Shen Z, Song J, Zhou Z, Wu A, Chen X

Emerging Strategies of Cancer Therapy Based on Ferroptosis

Adv Mater, 2018;30:1704007

 

635. Miao T, Wang J, Zeng Y, Liu G, Chen X

Polysaccharide-based Controlled Release Systems for Therapeutics Delivery and Tissue Engineering: from Bench to Bedside

Adv Sci, 2018;5(4):1700513.

 

634. Tian R, Jacobson O, Niu G, Kiesewetter DO, Wang Z, Zhu G, Ma Y, Liu G, Chen X

Evans Blue Attachment Enhances Somatostatin Receptor Subtype-2 Imaging and Radiotherapy

Theranostics, 2018; 8(3): 735-745.

 

633. Zhang P, Qin Z, Zhang L, Hua S, Guo Z, Chu C, Lin H, Zhang Y, Li W, Zhang X, Liu G, Chen X

Genetically Engineered Liposome-like Nanovesicles as Active Targeted Transport Platform

Adv Mater, 2018;30:1705350

 

632. Wang Z, Dai Y, Wang Z, Jacobson O, Zhang F, Yung BC, Zhang P, Gao H, Niu G, Liu G, Chen X

Metal Ion Assisted Interface Re-engineering of Ferritin Protein Nanocage for Enhanced Biofunctions and Cancer Therapy

Nanoscale, 2018;10(3):1135-1144.

 

631. Zhang J, Niu G, Fan X, Lang L, Hou G, Chen L, Wu H, Zhu Z, Li F, Chen X

Positron Emission Tomography Using a GRPR Antagonist 68Ga-RM26 in Healthy Volunteers and Prostate Cancer Patients

J Nucl Med. 2018;59:922-928

 

630. Ni Q, Zhang F, Zhang Y, Zhu G, Wang Z, Teng Z, Wang C, Niu G, Lu G, Zhang L, Chen X

In situ shRNA synthesis on drug-loaded DNA-polylactide nanoparticles for the treatment of multidrug resistant breast cancer  

Adv Mater, 2018;30:1705737

 

629. Li X, Yu S, Lee D, Kim G, Lee B, Cho Y, Zheng B-Y, Ke M-R, Huang J-D, Nam KT, Chen X, Yoon J

A facile supramolecular approach to nucleic acid-driven activatable nanotheranostics that overcome drawbacks of photodynamic therapy

ACS Nano, 2018; 12 (1): 681–688.

 

628. Cheng S, Lang L, Wang Z, Jacobson O, Yung B, Zhu G, Gu D, Ma Y, Zhu X, Niu G, Chen X

PET of Prostate Cancer with Ga-68 Labeled GRPR Agonist BBN7-14 and Antagonist RM26

Bioconjug Chem, 2018;29(2):410-419.  

 

627. Dai Y, Yang Z, Cheng S, Wang Z, Zhang R, Zhu G, Wang Z, Yung BC, Tian R, Jacobson O, Xu C, Ni Q, Song J, Sun X, Niu G, Chen X

Toxic Reactive Oxygen Species Enhanced Synergistic Combination Therapy by Self-Assembled Metal-phenolic Network Nanoparticles

Adv Mater, 2018;30:1704877

 

626. Wu H, Li F, Wang S, Lu J, Li J, Du Y, Sun X, Chen X, Gao J, Ling D.

Ceria nanocrystals decorated mesoporous silica nanoparticle based ROS-scavenging tissue adhesive for highly efficient regenerative wound healing

Biomaterials. 2018;151:66-77.

625. Wang Z, Gao H, Zhang Y, Liu G, Niu G, Chen X

Functional ferritin nanoparticles for biomedical applications

Front Chem Sci Eng, 2017;11(4):633-646.

 

624. Wu D, Li Y, Yang J, Shen J, Zhou J, Zhao R, Hu Q, Yu G, Tang G, Chen X

Supramolecular Nanomedicine Constructed from Cucurbit[8]uril-Based Amphiphilic Brush Copolymer for Cancer Therapy

ACS Appl Mater Interf, 2017;9 (51):44392–44401

 

623. Guo H, Cheng J, Wang J, Huang P, Liu Y, Jia Z, Chen X, Sui K, Li T, Nie Z.

Reprogrammable ultra-fast shape-transformation of macroporous composite hydrogel sheets

J Mater Chem B Mater Biol Med. 2017;5(16):2883-2887.

 

622. Zhang F, Khan S, Li R, Smolen JA, Zhang S, Zhu G, Su L, Jahnke AA, Elsabahy M, Chen X, Wooley KL

Design and development of multifunctional polyphosphoester-based nanoparticles for ultrahigh paclitaxel dual loading

Nanoscale. 2017;9(41):15773-15777.

 

621. Zhu G, Lynn GM, Jacobson O, Chen K, Liu Y, Zhang H, Ma Y, Zhang F, Tian R, Ni Q, Cheng S, Wang Z, Lu N, Yung BC, Wang Z, Lang L, Fu X, Jin A, Weiss ID, Vishwasrao H, Niu G, Shroff H, Klinman DM, Seder RA, Chen X

Albumin/Vaccine Nanocomplexes That Assemble In Vivo for Combination Cancer Immunotherapy

Nat Comm, 2017;8:1954.  

 

620. Yu G, Zhang M, Saha ML, Mao Z, Chen J, Yao Y, Zhou Z, Liu Y, Gao C, Chen X, Stang PJ

Antitumor Activity of a Unique Polymer That Incorporates a Fluorescent Self-Assembled Metallacycle

J Am Chem Soc, 2017;139(44):15940-15949.

 

619. Yu X, Gao D, Gao L, Lai J, Zhang C, Zhao Y, Zhong L, Jia B, Wang F, Chen X, Liu Z.

Inhibiting Metastasis and Preventing Tumor Relapse by Triggering Host Immunity with Tumor-Targeted Photodynamic Therapy Using Photosensitizer-Loaded Functional Nanographenes

ACS Nano. 2017;11(10):10147-10158.

 

618. Liu Y, Wang Z, Liu Y, Zhu G, Weiss OJ, Fu X, Bai R, Lin X, Lu N, Yang X, Fan W, Song J, Wang Z, Yu G, Zhang F, Kalish H, Niu G, Nie Z, Chen X

2D Gold Nanorings Enhance Tumor Uptake and Suppress Nanoparticle-Mononuclear Phagocyte System Interaction

ACS Nano, 2017;11(10):10539-10548.

 

617. Wu H, Li F, Wang S, Lu J, Li J, Du Y, Sun X, Chen X, Gao J, Ling D

Ceria nanocrystals decorated mesoporous silica nanoparticle based ROS-scavenging tissue adhesive for highly efficient regenerative wound healing

Biomaterials, 2017;151:66-77.

 

616. Zhu G, Mei L, Vishwasrao HD, Jacobson O, Wang Z, Liu Y, Yung BC, Fu X, Jin A, Niu G, Wang Q, Zhang F, Shroff H, Chen X

Intertwining DNA-RNA nanocapsules loaded with tumor neoantigens as synergistic nanovaccines for personalized cancer immunotherapy

Nat Comm, 2017;8:1482.

 

615. Chen W, Tian R, Xu C, Yung BC, Wang G, Liu Y, Zhang F, Zhou Z, Fu L, Chen X

Microneedle-array patches loaded with dual mineralized protein/peptide particles for type 2 diabetes therapy

Nat Comm, 2017;8:1777.

 

614. Min KH, Kim Y-H, Wang Z, Kim J, Kim JS, Kim SH, Kim K, Kwon IC, Kiesewetter DO, Chen X

Engineered Zn(II)-Dipicolylamine-Gold Nanorod Provides Effective Prostate Cancer Treatment by Combining siRNA Delivery and Photothermal Therapy

Theranostics, 2017;7(17):4240-4254.

 

613. Yu X, Yang K, Chen X, Li W

Black hollow silicon oxide nanoparticles as highly efficient photothermal agents in the second near-infrared window for in vivo cancer therapy

Biomaterials. 2017;143:120-129.

 

612. Shen Z, Chen T, Ma X, Ren W, Zhou Z, Zhu G, Liu Y, Song J, Li Z, Ruan H, Fan W, Lin L, Munasinghe J, Chen X, Wu A

Multifunctional Theranostic Nanoparticles Based on Exceedingly Small Magnetic Iron Oxide Nanoparticles for T1-Weighted Magnetic Resonance Imaging and Chemotherapy

ACS Nano, 2017;11(11):10992-11004.

 

611. Zhang F, Zhu G, Jacobson O, Liu Y, Chen K, Yu G, Ni Q, Fan J, Yang Z, Xu F, Fu X, Wang Z, Ma Y, Niu G, Zhao X, Chen X

Transformative Nanomedicine of an Amphiphilic Camptothecin Prodrug for Long Circulation and High Tumor Uptake in Cancer Therapy

ACS Nano, 2017;11(9):8838-8848.

 

610. Fan W, Yung B, Huang P, Chen X

Nanotechnology for multimodal synergistic cancer therapy

Chem Rev, 2017;117(22):13566-13638.

 

609. Li Y, Liu G, Ma J, Lin J, Lin H, Su G, Chen D, Ye S, Chen X, Zhu X, Hou Z.

Chemotherapeutic drug-photothermal agent co-self-assembling nanoparticles for near-infrared fluorescence and photoacoustic dual-modal imaging-guided chemo-photothermal synergistic therapy

J Control Release. 2017;258:95-107.

 

608. Wang J, Tao W, Chen X, Farokhzad OC, Liu G

Emerging advances in nanotheranostics with intelligent bioresponsive systems

Theranostics, 2017; 7(16):3915-3919.

 

607. Zhang X, Wang B, Zhao N, Tian Z, Dai Y, Nie Y, Tian J, Wang Z, Chen X

Improved Tumor Targeting and Longer Retention Time of NIR Fluorescent Probes Using Bioorthogonal Chemistry

Theranostics, 2017; 7(15):3794-3802.

 

606. Cui H, Chen X

Peptides and Peptide Conjugates in Medicine.

Adv Drug Deliv Rev. 2017 Feb;110-111:1-2.

 

605. Zhou Z, Bai R, Munasinghe J, Shen Z, Nie L, Chen X

T1-T2 Dual-Modal Magnetic Resonance Imaging: From Molecular Basis to Contrast Agents

ACS Nano, 2017;11(6):5227-5232.

 

604. Huang X, Chisholm J, Zhuang J, Xiao Y, Duncan G, Chen X, Suk JS, Hanes J

Protein Nanocages that Penetrate Airway Mucus and Tumor Tissue

PNAS, 2017;114(32):E6595-E6602.

 

603. Song J, Yang X, Yang Z, Lin L, Liu Y, Zhou Z, Shen Z, Yu G, Dai Y, Jacobson O, Munasinghe J, Teng G, Chen X

Rational Design of Branched Nanoporous Gold Nanoshells with Enhanced Physico-optical Properties for Optical Imaging and Cancer Therapy

ACS Nano, 2017;11(6):6102-6113.  

 

602. Wang S, Lin J, Wang Z, Zhou Z, Bai R, Lu N, Liu Y, Fu X, Jacobson O, Fan W, Qu J, Chen S, Wang T, Huang P, Chen X

Core-Satellite Polydopamine-Gadolinium Metallofullerene Nanotheranostics for Multimodal Imaging Guided Synergistic Cancer Therapy

Adv Mater, 2017; 29:1701013

 

601. Song J, Wu B, Zhou Z, Zhu G, Liu Y, Yang Z, Lin L, Yu G, Zhang F, Zhang G, Duan H, Stucky GD, Chen X

Double-Layered Plasmonic-Magnetic Vesicles by Self-Assembly of Janus Amphiphilic Au–Fe3O4 Nanoparticles

Angew Chem Int Ed Engl, 2017; 56:8110 –8114

 

600. Huang X, Liu Y, Yung B, Xiong Y, Chen X

Nanotechnology-Enhanced No-Wash Biosensors for In Vitro Diagnostics of Cancer

ACS Nano, 2017;11(6):5238-5292.

 

599. Yoon YI, Tang W, Chen X

Ultrasound-Mediated Diagnosis and Therapy

Small Methods, 2017;1:1700173

 

598. Fan W, Lu N, Xu C, Liu Y, Lin J, Wang S, Shen Z, Yang Z, Qu J, Wang T, Chen S, Huang P, Chen X

Enhanced Afterglow Performance of Persistent Luminescence Implants for Efficient Repeatable

Photodynamic Therapy

ACS Nano, 2017;11(6):5864-5872.  

 

597. Chen Y, Zhang L, LJ, Zhang P, Chen X, Xie M

Molecular Imaging of Acute Cardiac Transplant Rejection: Animal Experiments and Prospects

Transplantation, 2017;101(9):1977-1986.

 

596. Zhang R, Gao S, Wang Z, Han D, Liu L, Ma Q, Tan W, Tian J, Chen X

Multifunctional Molecular Beacon Micells for Intracellular mRNA Imaging and Synergistic Therapy in Multidrug-Resistant Cancer Cells

Adv Funct Mater, 2017;27:1701027 (Front Cover)

 

595. Jaobson O, Chen H, Niu G, Kiesewetter DO, Li Q, Yang G, Xu L, Dall’Acqua W, Tsui P, Peng L, Chen X

PET-guided evaluation and optimization of internalized antibody-drug conjugates targeting erythropoietin producing hepatoma A2 receptor

J Nucl Med, 2017;58(11):1838-1844.

 

594. Chen H, Tong X, Lang L, Jacobson O, Yung BC, Yang X, Bai R, Kiesewetter DO, Ma Y, Wu H, Niu G, Chen X

Quantification of Tumor Vascular Permeability and Blood Volume by Positron Emission Tomography

Theranostics, 2017; 7(9):2363-2376.

 

593. Chen W, Wang G, Yung BC, Qian Z, Chen X

Long-acting release formulation of exendin-4 based on biomimetic mineralization for type 2 diabetes

therapy

ACS Nano, 2017; 11(5):5062-5069.

 

592. Dai Y, Sun X, Chen X

Nanoparticle design strategies for enhanced anticancer therapy by exploiting tumour microenvironment

Chem Soc Rev, 2017;46(12):3830-3852.

 

591. Yang Z, Song J, Chen J, Wang F, Lin L, Liu Y, Zhang F, Yu G, Zhou Z, Fan W, Huang W, Fan Q, Chen X

Self-Assembly of Semiconducting-Plasmonic Gold Nanoparticles with Enhanced Optical Property for Photoacoustic Imaging and Photothermal Therapy

Theranostics, 2017;7(8):2177-2185.

 

590. Zhang J, Yang C, Zhang R, Chen R, Zhang Z, Zhang W, Peng S-H, Chen X, Liu G, Hsu C-S, Lee C-S

Biocompatible D–A Semiconducting Polymer Nanoparticle with Light-Harvesting Unit for Highly Effective Photoacoustic Imaging Guided Photothermal Therapy

Adv Funct Mater, 2017;27:1605094 (Inside Back Cover)

 

589. Yu X, Li A, Zhao C, Yang K, Chen X, Li W

Ultra-small Semimetal Nanoparticles of Bismuth for Dual-Modal CT/Photoacoustic Imaging and

Synergistic Thermoradiotherapy

ACS Nano, 2017; 11(4):3990-4001.

 

588. Zhou Z, Song J, Tian R, Yang Z, Yu G, Lin L, Zhang G, Fan W, Zhang F, Niu G, Nie L, Chen X

Activatable Singlet Oxygen Generation from Lipid Hydroperoxide Nanoparticles for Cancer Therapy

Angew Chem Int Ed Engl, 2017;56(23):6492-6496.

 

587. Yang Z, Tian R, Wu J, Fan Q, Yung BC, Niu G, Jacobson O, Wang Z, Liu G, Yu G, Huang W, Song J, Chen X

Impact of Semiconducting Perylene Diimide Nanoparticle Size on Lymph Node Mapping and Cancer Imaging

ACS Nano, 2017;11(4):4247-4255.

 

586. Chu C, Lin H, Liu H, Wang X, Wang J, Zhang P, Gao H, Huang C, Zeng Y, Tan Y, Liu G, Chen X

Tumor microenvironment-triggered supramolecular system as in situ nanotheranostic generator for enhanced cancer phototherapy

Adv Mater, 2017;29:1605928.

 

585. Chen H, Zhang W, Zhu G, Xie J, Chen X

Rethinking Cancer Nanotheranostics

Nat Rev Mater, 2017;2:17024

 

584. Lin LS, Yang X, Zhou Z, Yang Z, Jacobson O, Liu Y, Yang A, Niu G, Song J, Yang HH, Chen X

Yolk-Shell Nanostructure: An Ideal Architecture to Achieve Harmonious Integration of Magnetic-Plasmonic Hybrid Theranostic Platform

Adv Mater. 2017;29:1606681

 

583. Tang L, Zhang F, Yu F, Sun W, Song M, Chen X, Zhang X, Sun X

Croconaine nanoparticles with enhanced tumor accumulation for multimodality cancer theranostics

Biomaterials. 2017;129:28-36.

 

582. Guo H, Cheng J, Wang J, Huang P, Liu Y, Jia Z, Chen X, Sui K, Li T, Nie Z

Reprogrammable ultra-fast shape-transformation of macroporous composited hydrogel sheets

J Mater Chem B, 2017;5:2883-2887.

 

581. Xia Y, Zhang R, Wang Z, Tian J, Chen X

Recent Advances in High-Performance fluorescent and bioluminescent RNA Imaging Probes

Chem Soc Rev, 2017;46;2824-2843.

 

580. Shen Z, Wu A, Chen X

Current Detection Technologies of Circulating Tumor Cells

Chem Soc Rev, 2017;46:2038-2056 (Inside Front Cover)

 

579. Zhu G, Zhang F, Ni Q, Niu G, Chen X

Efficient Nanovaccine Delivery in Cancer Immunotherapy

ACS Nano. 2017;11(3):2387-2392.

 

578. Zhou Z, Tian R, Wang Z, Yang Z, Liu Y, Liu G, Wang R, Gao J, Song J, Nie L, Chen X

Artificial local magnetic field inhomogeneity enhances T2 relaxivity

Nat Comm, 2017;8: 15468

 

577. Lu N, Huang P, Fan W, Wang Z, Liu Y, Wang S, Zhang G, Hu J, Niu G, Leapman RD, Lu G, Chen X

Tri-Stimuli-Responsive Biodegradable Theranostics for Mild Hyperthermia Enhanced Chemotherapy

Biomaterials, 2017;126:39-48.

 

576. Li X, Kim J, Yoon J, Chen X

Cancer-Associated, Stimuli-Driven, Turn on Theranostics for Multimodal Imaging Guided Therapy

Adv Mater, 2017;29:1606857

 

575. Pelaz B, …Chen X, …Parak WJ

Diverse Applications of Nanomedicine

ACS Nano, 2017;11(3):2313-2381.

 

574. Liu D, Chen X.

An Ultrasensitive Biosensing Platform Employing Acetylcholinesterase and Gold Nanoparticles

Methods Mol Biol, 2017;1530:307-316.

 

573. Zhu G, Zhang H, Jacobson O, Wang Z, Chen H, Yang X, Niu G, Chen X

Combinatory screening of DNA aptamers for molecular imaging of HER2 in cancer

Bioconjugate Chem, 2017;28:1068-1075.

 

572. Zhang J, Zhang J, Li W, Chen R, Zhang Z, Zhang W, Tang Y, Chen X, Liu G, Lee CS

Degradable Hollow Mesoporous Silicon/Carbon Nanoparticles for Photoacoustic Imaging-Guided Highly Effective Chemo-Thermal Tumor Therapy in Vitro and in Vivo

Theranostics, 2017; 7(12):3007-3020.

 

571. Kim Y-H, Min KH, Wang Z, Kim J, Jacobson O, Huang P, Zhu G, Liu Y, Yung B, Niu G, Chen X

Development of sialic acid-coated nanoparticles for targeting cancer and efficient evasion of the immune system

Theranostics, 2017;7(4):962-973.

 

570. Wang RH, Bai J, Deng J, Fang CJ, Chen X

TAT-modified gold nanoparticle carrier with enhanced anticancer activity and size effect on

overcoming multidrug resistance

ACS Appl Mater Interfaces, 2017;9(7):5828-5837.

 

569. Liu Y, Wang S, Ma Y, Lin J, Wang HY, Gu Y, Chen X, Huang P

Ratiometric Photoacoustic Molecular Imaging for Methylmercury Detection in Living Subjects

Adv Mater, 2017 Feb 22. doi: 10.1002/adma.201606129.

 

568. Cai W, Gao H, Chu C, Wang X, Wang J, Zhang P, Lin G, Liu G, Chen X

Engineering phototheranostic nanoscale metal-organic frameworks for multi-modal imaging-guided cancer therapy

ACS Appl Mater Interfaces, 2017; 9(3): 2040-2051.

 

567. Li H, Zhang D, Gao M, Huang L, Tang L, Li Z, Chen X, Zhang X

Highly Specific C-C Bond Cleavage Induced FRET Fluorescence for in vivo Biological Nitric Oxide Imaging

Chem Sci, 2017; 8: 2199-2203

 

566. Fan W, Lu N, Huang P, Liu Y, Yang Z, Wang S, Yu G, Liu Y, Hu J, He Q, Qu J, Wang T, Chen X

Glucose-Responsive Sequential Generation of H2O2 and NO for Synergistic Cancer Starving-Like/Gas Therapy

Angew Chem Int Ed Engl, 2017;56(5):1229-1233. (Back cover)

 

565. Wang Z, Yan X, Sun X, Jacobson O, Sun W, Tong X, Xia Y, Ling D, Chen X

Improved Tumor Uptake by Optimizing Liposome Based RES Blockade Strategy

Theranostics, 2017; 7(2): 319-328.

 

564. Song J, Niu G, Chen X

Amphiphilic Polymer-Guided Plasmonic Assemblies and Their Biomedical Applications

Bioconjugate Chem, 2017; 28(1): 105–114

 

563. Shen Z, Wu A, Chen X

Iron Oxide Nanoparticles-based Contrast Agents for Magnetic Resonance Imaging

Mol Pharm, 2017;14(5):1352-1364.

 

562. Yang X, Wang Z, Zhang F, Zhu G, Song J, Teng G, Niu G, Chen X

Mapping Sentinel Lymph Node Metastasis by Dual-probe Optical Imaging

Theranostics, 2017; 7(1):153-163.

 

561. Kim J, Yung BC, Kim WJ, Chen X

Combination of nitric oxide and drug delivery systems: tools for overcoming drug resistance in chemotherapy

J Control Release, DOI: 10.1016/j.jconrel.2016.12.026.

 

560. Chen H, Jacobson O, Niu G, Weiss ID, Kiesewetter DO, Liu Y, Ma Y, Wu H, Chen

X

Novel molecular “add-on” based on Evans Blue confers superior pharmacokinetics and transforms drugs

to theranostic agents

J Nucl Med, 2017;58(4):590-597.

 

559. Xu C, Yang X, Fu X, Niu G, Hu S, Ali I, Chen X

Converting Red Blood Cells to Efficient Microreactors for Blood Detoxification

Adv Mater, 2016 Nov 28. doi: 10.1002/adma.201603673.

 

558. Zhang J, Niu G, Lang L, Li F, Fan X, Yan X, Yao S, Yan W, Huo L, Chen L, Li Z, Zhu Z, Chen X

Clinical translation of a dual integrin αvβ3 and GRPR targeting PET radiotracer 68Ga-NOTA-BBN-RGD

J Nucl Med. 2017;58(2):228-234. (Cover feature)

557. Yu G, Cook TR, Li Y, Yan X, Wu D, Shao L Shen J, Tang G, Huang F, Chen X, Stang PJ

A tetraphenylethene-based highly emissive metallacage as a component of theranostic supramolecular nanoparticles

PNAS, 2016;113(48):13720-13725.

 

556. Chu C, Ge S, Zhang J, Lin H, Liu G, Chen X

Enzyme-free colorimetric determination of EV71 virus using a 3D-MnO2-PEG nanoflower and 4-MBA-MA-AgNPs

Nanoscale. 2016;8(36):16168-16171.

 

555. Li A, Li X, Yu X, Li W, Zhao R, An X, Cui D, Chen X, Li W.

Synergistic thermoradiotherapy based on PEGylated Cu3BiS3 ternary semiconductor nanorods with strong absorption in the second near-infrared window

Biomaterials. 2016;112:164-175.

 

554. Wang Z, Zhang F, Wang Z, Fu X, Jin A, Yung BC, Fan J, Yang X, Niu G, Chen X

Hierarchical Assembly of Bioactive Amphiphilic Molecule Pairs into Supramolecular Nanofibril Self-Supportive Scaffolds for Stem Cell Differentiation

J Am Chem Soc, 2016;138(45):15027-15034.

 

553. Zhou Z, Song J, Nie L, Chen X

Reactive Oxygen Species Generating Systems Meeting Challenges of Photodynamic Cancer Therapy

Chem Soc Rev, 2016;45(23):6597-6626.

 

552. Jacobson O, Kiesewetter DO, Chen X

Albumin-Binding Evans Blue Derivatives for Diagnostic Imaging and Production of Long-Acting Therapeutics

Bioconjug Chem, 2016;27(10):2239–2247

 

551. Song J, Hu H, Wu K, Chen X

New Generation of Gold Nanoshell-Coated Esophageal Stent: Preparation and Biomedical Applications

ACS Appl Mater Interfaces, 2016;8 (41):27523–27529

 

550. Sun X, Yang L, Yan X, Sun Y, Zhao D, Ji Y, Wang K, Chen X, Shen B

DCE-MRI-Derived Parameters in Evaluating Abraxane-Induced Early Vascular Response and the Effectiveness of Its Synergistic Interaction with Cisplatin

PLoS One. 2016;11(9):e0162601.

 

549. Yu G, Zhao R, Wu D, Zhang F, Shao L, Zhou J, Yang J, Tang G, Chen X, Huang F

Pillar[5]arene-based amphiphilic supramolecular brush copolymers: fabrication, controllable

self-assembly and application in self-imaging targeted drug delivery

Polymer Chem, 2016;7:6178-6188.

 

548. Liu Y, Yang X, Huang Z, Huang P, Zhang Y, Deng L, Wang Z, Zhou Z, Liu Y, Kalish H, Khachab NM, Chen X, Nie Z

Magneto-Plasmonic Janus Vesicles for Magnetic Field-Enhanced Photoacoustic and Magnetic Resonance Imaging of Tumor

Angew Chem Int Ed Engl, 2016;55(49):15297-15300.

 

547. Zhang P, Zhuang R, Guo Z, Su X, Chen X, Zhang X

A Highly Efficient Approach to Copper-Mediated Radioiodination Approach using Using Aryl Boronic Acids

Chem Eur J, 2016;22(47):16783-16786.

 

546. Zhu C, Yang C, Wang Y, Lin G, Yang Y, Wang X, Zhu J, Chen X, Lu X, Liu G, Xia H.

CCCCC pentadentate chelates with planar Möbius aromaticity and unique properties.

Sci Adv, 2016 Aug 26;2(8):e1601031.

 

545. Fan W, Huang P, Chen X

Overcoming the Achilles’ heel of photodynamic therapy

Chem Soc Rev, 2016;45(23):6488-6519.

 

544. Tong X, Wang Z, Sun X, Song J, Jacobson O, Niu G, Kiesewetter DO, Chen X

Size dependent kinetics of gold nanorods in EPR mediated tumor delivery

Theranostics, 2016; 6(12): 2039-2051.

 

543. Wang S, Lin J, Wang T, Chen X, Huang P

Recent Advances in Photoacoustic Imaging for Deep-Tissue Biomedical Applications

Theranostics, 2016;6(13):2394-2413.

 

542. Fan J, He Q, Liu Y, Zhang F, Yang X, Wang Z, Lu N, Fan W, Lin L, Niu G, He N, Song J, Chen X

Light-Responsive Biodegradable Nanomedicine Overcomes Multidrug Resistance via NO-Enhanced Chemosensitization

ACS Appl Mater Interfaces. 2016 Jun 8;8(22):13804-11.

 

541. Sun X, Li Y, Liu T, Li Z, Zhang X, Chen X

Peptide-based imaging agents for cancer detection

Adv Drug Deliv Rev. 2016 Jun 18. pii: S0169-409X(16)30191-0.

 

540. Lin J, Zhang MG, Tang Y, Wen B, Hu H, Song J, Liu Y, Huang P, Chen X.

Temporal-spatially transformed synthesis and formation mechanism of gold bellflowers

Nanoscale, 2016 Apr 14;8(14):7430-4. (Front Cover)

 

539. Venugopalan A, Lee MJ, Niu G, Medina-Echeverz J, Tomita Y, Lizak MJ, Cultraro CM, Simpson RM, Chen X, Trepel JB, Guha U

EGFR-targeted therapy results in dramatic early lung tumor regression accompanied by imaging response and immune infiltration in EGFR mutant transgenic mouse models

Oncotarget. 2016;7(34):54137-54156.

 

538. Watson DC, Bayik D, Srivatsan A, Bergamaschi C, Valentin A, Niu G, Bear J, Monninger M, Sun M, Morales-Kastresana A, Jones JC, Felber BK, Chen X, Gursel I, Pavlakis GN

Efficient production and enhanced tumor delivery of engineered extracellular vesicles

Biomaterials. 2016 Jul 6;105:195-205.

 

537. Song J, Wang F, Yang X, Huang P, Nie L, Lin L, Niu G, Chen J, Chen X

Gold Nanoparticle Coated Carbon Nanotube Ring with Enhanced Raman Scattering and Photothermal Conversion Property for Theranostic Applications

J Am Chem Soc, 2016 Jun 8;138(22):7005-15.

 

536. Huang P, Lin J, Chen X

Graphene-Based Nanomaterials in Bioimaging

Adv Drug Deliv Rev, 2016;105(Pt B):242-254.

 

535. Liao HS, Lin J, Liu Y, Gao Y, Horkay F, Huang P, Jin A, Chen X

Self-assembly mechanisms of nanofibers from peptide amphiphiles in solution and on substrate surfaces

Nanoscale, 2016 Aug 4;8(31):14814-20.

 

534. Tong X, Srivatsan A, Jacobson O, Wang Y, Wang Z, Yang X, Niu G, Kiesewetter DO, Zheng H, Chen X

Monitoring Tumor Hypoxia Using 18F-FMISO PET and Pharmacokinetics Modeling after Photodynamic Therapy

Sci Rep, 2016 Aug 22;6:31551.

 

533. Wang S, Huang P, Chen X

Hierarchical Targeting Strategy for Enhanced Tumor Tissue Accumulation/Retention and Cellular Internalization

Adv Mater, 2016 Sep;28(34):7340-64.

 

532. Liu Y, Wang Z, Zhang H, Lang L, Ma Y, He Q, Lu N, Huang P, Liu Y, Gao S, Ma Q, Kiesewetter DO, Chen X

A Photothermally Responsive Nanoprobe for Bioimaging Based on the Edman Degradation

Nanoscale, 2016;8(20):10553-7.

 

531. Huang X, Zhan S, Xu H, Meng X, Xiong Y, Chen X

Ultrasensitive Fluorescence Immunoassay for the Detection of Ochratoxin A Using Catalase-Mediated Fluorescence Quenching of CdTe QDs

Nanoscale, 2016 Apr 28;8(17):9390-7.

 

530. Song J, Huang P, Chen X

Preparation of Plasmonic Vesicles from Amphiphilic Gold Nanocrystals Grafted with Polymer Brushes

Nat Protoc, 2016;11(11):2287-2299.

 

529. Zhang W, Wu P, Li F, Tong G, Chen X, Zhu Z

Potential Applications of Using 68Ga-Evans Blue PET/CT in the Evaluation of Lymphatic Disorder

Clin Nucl Med, 2016;41:302-308.

 

528. Wang Z, Huang P, Jacobson O, Wang Z, Liu Y, Lin L, Lin J, Lu N, Zhang H, Tian R, Niu G, Liu G, Chen X

Biomineralization-Inspired Synthesis of Copper Sulfide-Ferritin Nanocages as Cancer Theranostics

ACS Nano, 2016;10(3):3453-60.

 

527. Wang S, Huang P, Chen X

Programmed Specific Targeting in Nanomedicine

ACS Nano, 2016;10(3):2991-4.

 

526. Huang P, Wang M, Hu H, Yang X, Wen B, Wang Z, Song J, Zhang G, Niu G, Wang T, Huang P, Chen X

Multimodal Imaging Guided Cancer Phototherapy by Versatile Biomimetic Theranostics with UV and γ Irradiation Protection

Adv Mater, 2016 May;28(17):3273-9.

 

525. Liu Y, Nie L, Chen X

Photoacoustic molecular imaging: from multiscale biomedical applications towards early-stage theranostics

Trends Biotechnol, 2016;34:420-33.

 

524. Zhu G, Liu Y, Yang X, Kim Y-H, Zhang H, Jia R, Liao H-S, Jin A, Lin J, Aronova M, Leapman R, Nie Z, Niu G, Chen X

DNA-inorganic hybrid nanovaccine for cancer immunotherapy

Nanoscale, 2016;8:6684-6692

 

523. Liu Z, Chen X

Simple bioconjugate chemistry serves great clinical advances: Albumin as a versatile platform for diagnosis and precision therapy

Chem Soc Rev, 2016;45(5):1432-56.

 

522. Chen H, Song M, Tang J, Hu G, Xu S, Guo Z, Li N, Cui J, Zhang X, Chen X, Wang L.

Ultrahigh 19F Loaded Cu1.75S Nanoprobes for Simultaneous 19F Magnetic Resonance Imaging and Photothermal Therapy

ACS Nano, 2016;10(1):1355-62.

 

521. Xu C, Hu S, Chen X

Artificial cells: from basic science to applications

Mater Today, 2016;19(9):516-532.

 

520. Yan X, Niu G, Wang Z, Yang X, Kiesewetter DO, Jacobson O, Shen B, Chen X

[18F]NOTA-T140 Peptide for Noninvasive Visualization of CXCR4 Expression

Mol Imaging Biol, 2016;18(1):135-42.

 

519. Luo Y, Pan Q, Yao S, Zhang J, Yu M, Wu W, Xue H, Kiesewetter DO, Zhu Z, Li F, Zhao Y, Chen X

Glucagon-like peptide-1 receptor PET/CT with 68Ga-NOTA-exendin 4 for the localization of insulinoma: a prospective cohort study

J Nucl Med, 2016 May;57(5):715-20.

 

518. Luo Y, Li N, Kiesewetter DO, Chen X, Li F

68Ga-NOTA-exendin-4 PET/CT in localization of an occult insulinoma and appearance of coexisting esophageal carcinoma

Clin Nucl Med, 2016;41:341-343

 

517. Liu Y, Wang G, Zhang H, Ma Y, Lang L, Jacobson O, Kiesewetter DO, Zhu L, Gao S, Ma Q, Chen X

A Stable Evans Blue Derived Exendin-4 peptide for Type 2 Diabetes Treatment

Bioconjug Chem, 2016;27(1):54-8.

 

516. Lin L, Yang X, Niu G, Song J, Yang H-H, Chen X

Dual-enhanced photothermal conversion property of reduced graphene oxide-coated gold superparticles for light-triggered acoustic and thermal theranostics

Nanoscale, 2016; 8: 2116-2122

 

515. Chen H, Wang G, Lang L, Jacobson O, Kiesewetter DO, Liu Y, Ma Y, Zhang X, Wu H, Zhu L, Niu G, Chen X

Chemical conjugation of Evans blue derivative: a strategy to develop long-acting therapeutics through albumin binding

Theranostics, 2016; 6(2):243-253.

 

514. Xia Y, Tian J, Chen X

Effect of Surface Properties on Liposomal siRNA Delivery

Biomaterials, 2016;79:56-68. 

 

513. Song M, Liu T, Shi C, Zhang X, Chen X

Bioconjugated Manganese Dioxide Nanoparticles Enhance Chemotherapy Response by Priming Tumor-Associated Macrophages toward M1-like Phenotype and Attenuating Tumor Hypoxia

ACS Nano, 2016;10(1):633-47.

 

512. Ai X, Ho CJH, Aw J, Attia ABE, Wang X, Wang Y, Chen H, Gao M, Chen X, Yeow EKL, Liu G, Olivio M, Xing B

In vivo Covalent Cross-linking of Photon-converted Rare-earth Nanostructures for Tumor Localization and Theranostics

Nat Comm, 2016;7:10432.

 

511. Wang J, Mi P, Lin G, Wang Y, Liu G, Chen X

Molecular Imaging Guided Delivery of RNAi Therapeutics for Cancer

Adv Drug Deliv Rev, 2016 Sep 1;104:44-60.

 

510. Niu G, Chen X

RGD PET: From Lesion Detection to Therapy Response Monitoring

J Nucl Med, 2016 Apr;57(4):501-2.

 

509. Guo S, Lv L, Shen Y, Hu Z, He Q, Chen X

A nanoparticulate pre-chemosensitizer for efficacious chemotherapy of multidrug resistant breast cancer

Sci Rep, 2016;6:21459.

 

508. Wang Y, Su T, Chen J, Ma S, Zhang X, Li X, Chen Y, Cao L, Yang B, Liu G, Cao J, Chen X, Chen Y, Cao F

In vivo MR and Fluorescence Dual-modality Imaging of Atherosclerosis Characteristics in Mice Using Profilin-1 Targeted Magnetic Nanoparticles

Theranostics, 2016; 6(2):272-286.

 

507. Zhang J, Li D, Lang L, Zhu Z, Wang L, Wu P, Niu G, Li F, Chen X

68Ga-NOTA-Aca-BBN(7-14) PET/CT in Healthy Volunteers and Glioma Patients

J Nucl Med, 2016 Jan;57(1):9-14.

 

506. Chen H, Niu G, Wu H, Chen X

Clinical Application of Radiolabeled RGD Peptides for PET Imaging of Integrin αvβ3

Theranostics, 2016; 6(1): 78-92

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