Xiaowan Huang

Research Fellow

E-mail: huangxiaowan@nus.edu.sg

Research Interest

Targeted protein degradation

Education Background

PhD, Biomedical Engineering, South China University of Technology, 2022

BSc, Pharmaceutical preparations, Zhengzhou University, 2017

1. Xiaowan Huang#; Ziyang Cao#; Jieying Qian#; Tao Ding; Yanxia Wu; Hao Zhang; Suqin Zhong; Xiaoli Wang; Xiaoguang Ren; Wang Zhang; Youcui Xu; Guangyu Yao; Xingwu Wang; Xianzhu Yang*; Longping Wen*; Yunjiao Zhang*. Nanoreceptors promote mutant p53 protein degradation by mimicking selective autophagy receptors, Nature Nanotechnology, 2024, 19(4):545-553.

2. Yunjiao Zhang#; Xiaowan Huang#; Liansheng Wang#; Cong Cao; Hao Zhang; Pengfei Wei; He Ding; Yang Song; Ziying Chen; Jieying Qian; Suqin Zhong; Zefeng Liu; Meimei Wang; Wenbin Zhang; Wenwei Jiang; Jie Zeng; Guangyu Yao*; Long-ping Wen*. Glutathionylation-dependent proteasomal degradation of wide-spectrum mutant p53 proteins by engineered zeolitic imidazolate framework-8, Biomaterials, 2021, 271: 120720.

3.   Zefeng Liu#; Xiaohan Hao#; Jieying Qian; Hao Zhang; Hui Bao; Qiong Yang; Weiguang Gu*; Xiaowan Huang*; Yunjiao Zhang*; Enzyme/pH Dual-Responsive Engineered Nanoparticles for Improved Tumor Immuno-Chemotherapy, ACS Applied Materials & Interfaces, 2024, 16(10):12951-12964.