Xue Dong

Visiting Scholar

Research interest

Engineered living materials for microbiota and immune modulation

Work Experience

2022-present, Xinqiao Hospital of Army Military Medical University, Research associate

E-mail: dongx1203@163.com

Education Background

Ph.D, Chemistry and Physics of Polymers, Wuhan University, 2017-2022

B.Sc. Chemistry, Lanzhou University, 2013-2017

Publications

Di-Wei Zheng#, Xue Dong#, Pei Pan, Ke-Wei Chen, Jin-Xuan Fan, Si-Xue Cheng and Xian-Zheng Zhang*. Phage-guided modulation of the gut microbiota of mouse models of colorectal cancer augments their responses to chemotherapy. Nature Biomedical Engineering 2019, 3, 717-728

Xue Dong, Pei Pan, Di-Wei Zheng, Peng Bao, Xuan Zeng, Xian-Zheng Zhang*. Bioinorganic hybrid bacteriophage for modulation of intestinal microbiota to remodel tumor-immune microenvironment against colorectal cancer. Science Advances 2020, 6, eaba1590

Xue Don, Wei Wu, Pei Pan and Xian-Zheng Zhang*. Engineered living materials for advanced diseases therapy. Advanced Materials 2023, 2304963

Xue Dong, Pei Pan, Qiu-Ling Zhang, Peng Bao, and Xian-Zheng Zhang*. Targeting DNA mismatch repair pathway by CRISPR nanosystem for boosting checkpoint blockade cancer immunotherapy. Nano Today 2022, 45, 101555

Xue Dong, Wei Wu, Cheng-Ling Zhang, Rui-Hao Huang, Qin Wen   and Xi Zhang. Virus-mimicking nanodrug active crossing of the blood–brain barrier via transcytosis against central nervous system leukemia. Nano Today 2024, 59, 102536.

Xue Dong, Pei Pan, Jing-Jie Ye, Qiu-Ling Zhang and Xian-Zheng Zhang*. Hybrid M13 bacteriophage-based vaccine platform for personalized cancer immunotherapy. Biomaterials 2022, 289, 121763-121763

Xue Dong, Pei Pan, Qiu-Ling Zhang, Jing-Jie Ye and Xian-Zheng Zhang*. Virus-enabled biomineralization and chemical crosslinking of bioactive hydrogel for synergetic cancer therapy. Nano Letters, 2023, 23 1219-1228

Pei Pan#, Xue Dong#, Ying Chen and Xian-Zheng Zhang*. Engineered bacteria for enhanced radiotherapy against breast carcinoma. ACS Nano 2022, 6, 801-812

Pei Pan#, Xue Dong#, Ying Chen and Xian-Zheng Zhang*, A heterogenic membrane-based biomimetic hybrid nanoplatform for combining radiotherapy and immunotherapy against breast cancer. Biomaterials 2022, 289, 121810

Research Grants:

National Natural Science Foundation of China (82300207, 2023-2026)，host

Science-Health Joint Medical Scientific Research Project of Chongqing (2023QNXM032, 2023-2024), host

Natural Science Foundation of Chongqing (CSTB2024NSCQ-MSX0654,2024-2027), host

New Chongqing Youth Innovative Talent Project (CSTB2024NSCQ-QCXMX0039), host

Subject Talent Construction Project of the Second Affiliated Hospital of Army Military Medical University (2023XKRC015, 2023-2026), host